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The map label for this gene is putA [H]

Identifier: 87198728

GI number: 87198728

Start: 743286

End: 746729

Strand: Reverse

Name: putA [H]

Synonym: Saro_0704

Alternate gene names: 87198728

Gene position: 746729-743286 (Counterclockwise)

Preceding gene: 87198730

Following gene: 87198727

Centisome position: 20.97

GC content: 68.35

Gene sequence:

>3444_bases
ATGACCCAGACCGCGCCCTTCGCCGCATTCGCGCCCCGCCATTCCGTGCCCTCCGACCTGCGCCGGGCGATTACCGCCGC
CACCCGCCGCGCGGAACGCGAGTGCATGGTCATGCTCCTGCCGGAAGCAACCTTGCCACAGGCAACCCGGGCTTCGGCAC
AGGCGCTGGCACGCAAGCTGGTCGAGGCCCTGCGCGCCAAGCCGCGCGGGAACGGGGTGGAGCAACTCGTGCAGGAGTAT
GCCCTCTCGACGCACGAAGGCGTCGCCCTGATGTGTCTTGCCGAGGCGTTGTTGCGCATTCCCGATAACGATACGCGCGA
CGATCTCATCCGCGACAAGATCGCGGGAGGCGACTGGCTGGCGCACCTCGGCGGCGACCGTTCGCTCTTCGTCAACGCCG
CGACGTGGGGCCTCGTCGTCACCGGGAAGCTTGCCTCCAGCGTCGACGACACCGGCCTTGGCGCGGCCCTCACCCGCCTC
ATCGCCCGTGCGGGCGAACCTGTCATCCGCCGCGGCGTCGACCTCGCCATGCGCATGATGGGCGAACAGTTCGTCACCGG
CGAGACCATCGACGAGGCGCTGAAGCGCGCCCGTCCGCTCGAGGATCGTGGCTTCCGCTACAGCTATGACATGCTGGGCG
AGGCGGCCATGACTGCAAGCGACGCCGCCCGCTACCATGCAGATTACCAGGCCGCCATCCACGCAATCGGCAAGGCCGCC
GCACGTCGCGGCGTCTACGAAGGCCCCGGCATCTCGATCAAGCTCTCCGCGCTGCACCCGCGTTACGCGCGCGCGCAGCA
GGACCGCGTGTTCGCCGAACTCCTGCCCCGTCTCAAGGCGCTGGCTTATCTCGCGTTGCGCTACGACATCGGCCTCAACA
TCGATGCCGAAGAGGCCGACCGCCTCGAACTCTCGCTCGACCTGCTCGAAGAGCTGGCGATGGACCCGGAGCTTGCAGGC
TGGAACGGACTGGGCTTCGTCGTCCAGGCCTACGGCAAGCGCTGCCCCTTCGTAATCGACTGGATTGTCGATCTTGCCCG
CAGGTCGGGCCGCAGGATCATGGTCCGCCTCGTCAAGGGCGCCTATTGGGACGCAGAGATCAAGCGTGCGCAGGTCGACG
GGCAGTCCGGCTTCCCGGTCTACACCCGCAAGGCCCACACCGATGTCGCCTATATCGCCTGTGCCCGCCGGCTGCTCGCC
GCGACCGACGTCGTGTTCCCCCAGTTCGCCACCCACAACGCCCAGACACTCGCCACCATCCACGAGATGGCAGGCCCGGA
CTTTGCTGTTGGCCGTTACGAGTTCCAGTGCCTCCACGGCATGGGCGAACCGCTCTATGACGAGGTTGTCGGCAAGGACA
AGCTGGACCGCCCCTGCCGCATCTACGCGCCGGTCGGCACGCACGAAACGCTGCTGGCCTACCTCGTCCGCCGCTTGCTG
GAAAACGGCGCGAACTCTTCATTCGTCAACCGCATCGCCAACCCGGACGTGCCGGTCGATGAAATCGTTGCCGATCCCGT
GGCGCAGGTTGCCGCTGATGCCGATCCCGGCGCGCCCCATCCCCTGATCGCCCTTCCCGCCGCGCTTTATCCCGACCGCC
GCAACAGCAGCGGTCTCGACCTTGCGGACGAAAGCACCCTCGCCGCCCTCACGGACCGATTCCAGGCGATTTCCGCCCAT
TCGCGTCACGCCCACCCGTCCGCCGACCTGCCCCACGTCAATCCGCGCCCGGTTCTGAATCCGGCGAACCACAGGGATGT
AGTTGGCCACGTCAGCGAGGCCGCACCAGCGGCTGCTGGCATGGCAGCCAGCCTCGCCGCAGCCTCGCGCTGGAGCGCGA
CGCCCGTAGCCGCCCGCGCCATGATCCTGGAACGCGCGGCAGACGCCATGCAGGCGGCTATGCCCGAACTCATCGCGCTG
ATCGTGCGCGAGGCTGGAAAGTCCGTGTCCAACGCCATTGCCGAAGTGCGCGAGGCTGTGGATTTCCTGCGCTATTACGC
CAGCCAGGCGCCTGCCATGTCCGGTTCGCGGCCTCTCGGGGTCGCCTTGTGCATCAGCCCGTGGAACTTCCCCCTCGCCA
TCTTCACCGGCCAGGTGGCGGCCGCGCTCATGGCGGGCAACCCGGTCCTCGCCAAGCCTGCCGAAGAAACGCCGCTCATT
GCCTCTGAAGCCGTGCGCATCCTCCATGAAGCGGGCGTACCCGACGATGCCCTCGTATTCCTGCCGGGAGACGGCGCCAT
CGGAGCCGCACTGGTCGCTGCGCCGGAAATCGCCGCCGTGCTTTTCACCGGATCGACGGAAGTCGGCCGTTTGATCCAGC
GCCAGCTCGCCACCCGGCTTTCCGCGGAGGGCCGCCCGATCCCTCTGATTGCCGAAACCGGCGGCCAGAACGCGATGATC
GTCGACAGTTCCGCGCTTGCCGAACAGGTCGTGGCCGATGTGATCGCATCTGCCTTCGACAGCGCGGGCCAACGCTGTTC
GGCCCTGCGCGTCCTGTGCCTCCAGGAGGACGTTGCGGATCACGTCCTCGCCATGCTGCGCGGCGCGCTGGCGGAACTCA
CGGTCGGTCCGACCGACCGCCTCAGCGCCGACATTGGCCCCGTCATCGCCGCCGAGGCGCGCGAAGCGATCGAGGCGCAC
GTCGCCCGCATGGAAGCTGCCGGTTGCCCAGTCCACCGCCTGCCGCTCGGCACCGCCACCAACGAGGGCACTTTCGTTGC
CCCGACGATCATCGAACTGTCCGCCCCCGATCTCCTCACGCGCGAGGTCTTCGGGCCGGTCCTCCACGTCATCCGCTTCC
GCCGAGCCGACATGGACGCCATGGTCGAGCGCATCAATGCCTGGGGCTATGGCCTGACCTTCGGCCTCCACACCCGCCTC
GACGAGACGGTCGCCCGCGTTACGGCGAAGGCCCATGCTGGCAACATCTACGTCAACCGGAACGTCATTGGCGCGGTGGT
CGGCGTCCAGCCGTTCGGCGGCCACGGCCTGTCCGGCACGGGCCCGAAAGCAGGCGGCCCGCTTTACCTGCGCCGCCTTG
TCGCCAGCGCCCCTGCCGCACCCGCACTGGAGTTGACTGAGCGCGAACTGCCTGGCCCCGTCGGCGAACGCAACATCTAC
GCCCTGCGCCCCGTAGGCCGGGTCCTTGTCGCCGCCCAGTCGCCAGAGCGCCTTGCCGCCCTCACCAGCCGCGTCGAACG
GCTCGGCGGCACACCCATCGCGGCCGACGATGGCTGGCAGGCGCAAGGCCCCTTCGCCCGCGCCCTTGTCGAAGGCGACG
CGGCGTTCATCCTCTCTTTCCAGCAGGCCGTGGCGGCCCTCGACGGGCCCATCGCACCTGTCCTTGCCTCTGCGGACGAC
GACACGATGCTGGTGGCCGAGGTGTCGCTCTCGATCAACACCACCGCCGCTGGCGGCAACGCCAGCCTGATGGCCATGGC
CTGA

Upstream 100 bases:

>100_bases
CGGACTTTAGACCTTTGACTGGCCAATCAAAAGACATTTCACCTCACCGGGGGCGCCGGATAGGTCGGAACGCCTTGCAT
CTGGATGATATGATCGCGCC

Downstream 100 bases:

>100_bases
TGCCGTTTCACTTGCGCCGGTTGCCCGCATTCCTCCCAATTGTTAGGCTGCCAAACGGAAGAGGAATGACACATGACTGG
CAGTACACGTGATTTCACAG

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1147; Mature: 1146

Protein sequence:

>1147_residues
MTQTAPFAAFAPRHSVPSDLRRAITAATRRAERECMVMLLPEATLPQATRASAQALARKLVEALRAKPRGNGVEQLVQEY
ALSTHEGVALMCLAEALLRIPDNDTRDDLIRDKIAGGDWLAHLGGDRSLFVNAATWGLVVTGKLASSVDDTGLGAALTRL
IARAGEPVIRRGVDLAMRMMGEQFVTGETIDEALKRARPLEDRGFRYSYDMLGEAAMTASDAARYHADYQAAIHAIGKAA
ARRGVYEGPGISIKLSALHPRYARAQQDRVFAELLPRLKALAYLALRYDIGLNIDAEEADRLELSLDLLEELAMDPELAG
WNGLGFVVQAYGKRCPFVIDWIVDLARRSGRRIMVRLVKGAYWDAEIKRAQVDGQSGFPVYTRKAHTDVAYIACARRLLA
ATDVVFPQFATHNAQTLATIHEMAGPDFAVGRYEFQCLHGMGEPLYDEVVGKDKLDRPCRIYAPVGTHETLLAYLVRRLL
ENGANSSFVNRIANPDVPVDEIVADPVAQVAADADPGAPHPLIALPAALYPDRRNSSGLDLADESTLAALTDRFQAISAH
SRHAHPSADLPHVNPRPVLNPANHRDVVGHVSEAAPAAAGMAASLAAASRWSATPVAARAMILERAADAMQAAMPELIAL
IVREAGKSVSNAIAEVREAVDFLRYYASQAPAMSGSRPLGVALCISPWNFPLAIFTGQVAAALMAGNPVLAKPAEETPLI
ASEAVRILHEAGVPDDALVFLPGDGAIGAALVAAPEIAAVLFTGSTEVGRLIQRQLATRLSAEGRPIPLIAETGGQNAMI
VDSSALAEQVVADVIASAFDSAGQRCSALRVLCLQEDVADHVLAMLRGALAELTVGPTDRLSADIGPVIAAEAREAIEAH
VARMEAAGCPVHRLPLGTATNEGTFVAPTIIELSAPDLLTREVFGPVLHVIRFRRADMDAMVERINAWGYGLTFGLHTRL
DETVARVTAKAHAGNIYVNRNVIGAVVGVQPFGGHGLSGTGPKAGGPLYLRRLVASAPAAPALELTERELPGPVGERNIY
ALRPVGRVLVAAQSPERLAALTSRVERLGGTPIAADDGWQAQGPFARALVEGDAAFILSFQQAVAALDGPIAPVLASADD
DTMLVAEVSLSINTTAAGGNASLMAMA

Sequences:

>Translated_1147_residues
MTQTAPFAAFAPRHSVPSDLRRAITAATRRAERECMVMLLPEATLPQATRASAQALARKLVEALRAKPRGNGVEQLVQEY
ALSTHEGVALMCLAEALLRIPDNDTRDDLIRDKIAGGDWLAHLGGDRSLFVNAATWGLVVTGKLASSVDDTGLGAALTRL
IARAGEPVIRRGVDLAMRMMGEQFVTGETIDEALKRARPLEDRGFRYSYDMLGEAAMTASDAARYHADYQAAIHAIGKAA
ARRGVYEGPGISIKLSALHPRYARAQQDRVFAELLPRLKALAYLALRYDIGLNIDAEEADRLELSLDLLEELAMDPELAG
WNGLGFVVQAYGKRCPFVIDWIVDLARRSGRRIMVRLVKGAYWDAEIKRAQVDGQSGFPVYTRKAHTDVAYIACARRLLA
ATDVVFPQFATHNAQTLATIHEMAGPDFAVGRYEFQCLHGMGEPLYDEVVGKDKLDRPCRIYAPVGTHETLLAYLVRRLL
ENGANSSFVNRIANPDVPVDEIVADPVAQVAADADPGAPHPLIALPAALYPDRRNSSGLDLADESTLAALTDRFQAISAH
SRHAHPSADLPHVNPRPVLNPANHRDVVGHVSEAAPAAAGMAASLAAASRWSATPVAARAMILERAADAMQAAMPELIAL
IVREAGKSVSNAIAEVREAVDFLRYYASQAPAMSGSRPLGVALCISPWNFPLAIFTGQVAAALMAGNPVLAKPAEETPLI
ASEAVRILHEAGVPDDALVFLPGDGAIGAALVAAPEIAAVLFTGSTEVGRLIQRQLATRLSAEGRPIPLIAETGGQNAMI
VDSSALAEQVVADVIASAFDSAGQRCSALRVLCLQEDVADHVLAMLRGALAELTVGPTDRLSADIGPVIAAEAREAIEAH
VARMEAAGCPVHRLPLGTATNEGTFVAPTIIELSAPDLLTREVFGPVLHVIRFRRADMDAMVERINAWGYGLTFGLHTRL
DETVARVTAKAHAGNIYVNRNVIGAVVGVQPFGGHGLSGTGPKAGGPLYLRRLVASAPAAPALELTERELPGPVGERNIY
ALRPVGRVLVAAQSPERLAALTSRVERLGGTPIAADDGWQAQGPFARALVEGDAAFILSFQQAVAALDGPIAPVLASADD
DTMLVAEVSLSINTTAAGGNASLMAMA
>Mature_1146_residues
TQTAPFAAFAPRHSVPSDLRRAITAATRRAERECMVMLLPEATLPQATRASAQALARKLVEALRAKPRGNGVEQLVQEYA
LSTHEGVALMCLAEALLRIPDNDTRDDLIRDKIAGGDWLAHLGGDRSLFVNAATWGLVVTGKLASSVDDTGLGAALTRLI
ARAGEPVIRRGVDLAMRMMGEQFVTGETIDEALKRARPLEDRGFRYSYDMLGEAAMTASDAARYHADYQAAIHAIGKAAA
RRGVYEGPGISIKLSALHPRYARAQQDRVFAELLPRLKALAYLALRYDIGLNIDAEEADRLELSLDLLEELAMDPELAGW
NGLGFVVQAYGKRCPFVIDWIVDLARRSGRRIMVRLVKGAYWDAEIKRAQVDGQSGFPVYTRKAHTDVAYIACARRLLAA
TDVVFPQFATHNAQTLATIHEMAGPDFAVGRYEFQCLHGMGEPLYDEVVGKDKLDRPCRIYAPVGTHETLLAYLVRRLLE
NGANSSFVNRIANPDVPVDEIVADPVAQVAADADPGAPHPLIALPAALYPDRRNSSGLDLADESTLAALTDRFQAISAHS
RHAHPSADLPHVNPRPVLNPANHRDVVGHVSEAAPAAAGMAASLAAASRWSATPVAARAMILERAADAMQAAMPELIALI
VREAGKSVSNAIAEVREAVDFLRYYASQAPAMSGSRPLGVALCISPWNFPLAIFTGQVAAALMAGNPVLAKPAEETPLIA
SEAVRILHEAGVPDDALVFLPGDGAIGAALVAAPEIAAVLFTGSTEVGRLIQRQLATRLSAEGRPIPLIAETGGQNAMIV
DSSALAEQVVADVIASAFDSAGQRCSALRVLCLQEDVADHVLAMLRGALAELTVGPTDRLSADIGPVIAAEAREAIEAHV
ARMEAAGCPVHRLPLGTATNEGTFVAPTIIELSAPDLLTREVFGPVLHVIRFRRADMDAMVERINAWGYGLTFGLHTRLD
ETVARVTAKAHAGNIYVNRNVIGAVVGVQPFGGHGLSGTGPKAGGPLYLRRLVASAPAAPALELTERELPGPVGERNIYA
LRPVGRVLVAAQSPERLAALTSRVERLGGTPIAADDGWQAQGPFARALVEGDAAFILSFQQAVAALDGPIAPVLASADDD
TMLVAEVSLSINTTAAGGNASLMAMA

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source, and also functions as a transcriptional repressor of its own gene [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI238859541, Length=466, Percent_Identity=31.1158798283262, Blast_Score=180, Evalue=6e-45,
Organism=Homo sapiens, GI25777736, Length=466, Percent_Identity=31.3304721030043, Blast_Score=180, Evalue=7e-45,
Organism=Homo sapiens, GI25777734, Length=466, Percent_Identity=31.3304721030043, Blast_Score=180, Evalue=7e-45,
Organism=Homo sapiens, GI21361176, Length=458, Percent_Identity=28.6026200873362, Blast_Score=160, Evalue=7e-39,
Organism=Homo sapiens, GI25777724, Length=463, Percent_Identity=30.0215982721382, Blast_Score=157, Evalue=6e-38,
Organism=Homo sapiens, GI153266822, Length=457, Percent_Identity=26.2582056892779, Blast_Score=155, Evalue=2e-37,
Organism=Homo sapiens, GI21614513, Length=423, Percent_Identity=29.0780141843972, Blast_Score=155, Evalue=3e-37,
Organism=Homo sapiens, GI25777730, Length=453, Percent_Identity=29.5805739514349, Blast_Score=154, Evalue=7e-37,
Organism=Homo sapiens, GI25777732, Length=454, Percent_Identity=29.0748898678414, Blast_Score=151, Evalue=4e-36,
Organism=Homo sapiens, GI12007648, Length=429, Percent_Identity=29.3706293706294, Blast_Score=149, Evalue=2e-35,
Organism=Homo sapiens, GI25777728, Length=416, Percent_Identity=29.3269230769231, Blast_Score=147, Evalue=7e-35,
Organism=Homo sapiens, GI238814322, Length=422, Percent_Identity=27.7251184834123, Blast_Score=146, Evalue=1e-34,
Organism=Homo sapiens, GI115387104, Length=423, Percent_Identity=28.3687943262411, Blast_Score=140, Evalue=6e-33,
Organism=Homo sapiens, GI4507229, Length=431, Percent_Identity=28.3062645011601, Blast_Score=140, Evalue=7e-33,
Organism=Homo sapiens, GI11095441, Length=427, Percent_Identity=27.4004683840749, Blast_Score=136, Evalue=1e-31,
Organism=Homo sapiens, GI25777721, Length=444, Percent_Identity=27.4774774774775, Blast_Score=132, Evalue=3e-30,
Organism=Homo sapiens, GI188035924, Length=449, Percent_Identity=26.2806236080178, Blast_Score=129, Evalue=2e-29,
Organism=Homo sapiens, GI310128103, Length=434, Percent_Identity=26.7281105990783, Blast_Score=127, Evalue=5e-29,
Organism=Homo sapiens, GI310128093, Length=424, Percent_Identity=26.1792452830189, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI25952152, Length=422, Percent_Identity=27.7251184834123, Blast_Score=120, Evalue=1e-26,
Organism=Homo sapiens, GI25777726, Length=464, Percent_Identity=26.7241379310345, Blast_Score=118, Evalue=4e-26,
Organism=Homo sapiens, GI310128091, Length=399, Percent_Identity=26.5664160401003, Blast_Score=112, Evalue=2e-24,
Organism=Homo sapiens, GI206597441, Length=421, Percent_Identity=24.7030878859857, Blast_Score=110, Evalue=9e-24,
Organism=Homo sapiens, GI206597439, Length=421, Percent_Identity=24.7030878859857, Blast_Score=110, Evalue=9e-24,
Organism=Homo sapiens, GI22907049, Length=421, Percent_Identity=24.7030878859857, Blast_Score=110, Evalue=9e-24,
Organism=Homo sapiens, GI4502043, Length=341, Percent_Identity=25.8064516129032, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI238814371, Length=341, Percent_Identity=25.8064516129032, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI71773324, Length=341, Percent_Identity=25.8064516129032, Blast_Score=100, Evalue=7e-21,
Organism=Homo sapiens, GI4557303, Length=403, Percent_Identity=21.5880893300248, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI73466520, Length=403, Percent_Identity=21.5880893300248, Blast_Score=99, Evalue=3e-20,
Organism=Homo sapiens, GI310128087, Length=243, Percent_Identity=28.3950617283951, Blast_Score=91, Evalue=5e-18,
Organism=Homo sapiens, GI73695881, Length=345, Percent_Identity=24.3478260869565, Blast_Score=91, Evalue=9e-18,
Organism=Homo sapiens, GI73695879, Length=345, Percent_Identity=24.3478260869565, Blast_Score=91, Evalue=9e-18,
Organism=Homo sapiens, GI310128089, Length=353, Percent_Identity=26.0623229461756, Blast_Score=88, Evalue=6e-17,
Organism=Homo sapiens, GI301500698, Length=272, Percent_Identity=29.0441176470588, Blast_Score=85, Evalue=3e-16,
Organism=Homo sapiens, GI310128095, Length=317, Percent_Identity=26.1829652996845, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI310128097, Length=254, Percent_Identity=27.9527559055118, Blast_Score=75, Evalue=4e-13,
Organism=Homo sapiens, GI310128101, Length=189, Percent_Identity=26.4550264550265, Blast_Score=70, Evalue=2e-11,
Organism=Homo sapiens, GI310128099, Length=189, Percent_Identity=26.4550264550265, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI1787250, Length=1243, Percent_Identity=55.7522123893805, Blast_Score=1291, Evalue=0.0,
Organism=Escherichia coli, GI87081896, Length=460, Percent_Identity=31.304347826087, Blast_Score=167, Evalue=3e-42,
Organism=Escherichia coli, GI1788042, Length=437, Percent_Identity=32.7231121281465, Blast_Score=164, Evalue=4e-41,
Organism=Escherichia coli, GI1789015, Length=461, Percent_Identity=30.8026030368764, Blast_Score=161, Evalue=3e-40,
Organism=Escherichia coli, GI1787684, Length=464, Percent_Identity=28.8793103448276, Blast_Score=145, Evalue=2e-35,
Organism=Escherichia coli, GI1786504, Length=459, Percent_Identity=28.9760348583878, Blast_Score=145, Evalue=2e-35,
Organism=Escherichia coli, GI1787558, Length=411, Percent_Identity=30.4136253041363, Blast_Score=140, Evalue=3e-34,
Organism=Escherichia coli, GI1787715, Length=450, Percent_Identity=30.2222222222222, Blast_Score=137, Evalue=4e-33,
Organism=Escherichia coli, GI87081926, Length=422, Percent_Identity=29.3838862559242, Blast_Score=123, Evalue=7e-29,
Organism=Escherichia coli, GI87082295, Length=419, Percent_Identity=29.1169451073986, Blast_Score=123, Evalue=7e-29,
Organism=Escherichia coli, GI1787653, Length=258, Percent_Identity=25.5813953488372, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17534447, Length=481, Percent_Identity=31.8087318087318, Blast_Score=177, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI115534176, Length=484, Percent_Identity=28.9256198347107, Blast_Score=166, Evalue=9e-41,
Organism=Caenorhabditis elegans, GI115532534, Length=413, Percent_Identity=32.2033898305085, Blast_Score=160, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI25144435, Length=455, Percent_Identity=30.3296703296703, Blast_Score=155, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI25143874, Length=419, Percent_Identity=27.9236276849642, Blast_Score=151, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI25143876, Length=420, Percent_Identity=28.0952380952381, Blast_Score=151, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI32564736, Length=411, Percent_Identity=30.9002433090024, Blast_Score=147, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI133930964, Length=423, Percent_Identity=28.1323877068558, Blast_Score=142, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17562198, Length=459, Percent_Identity=29.6296296296296, Blast_Score=141, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI32564151, Length=414, Percent_Identity=30.1932367149758, Blast_Score=135, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17534119, Length=457, Percent_Identity=27.5711159737418, Blast_Score=133, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI17551164, Length=425, Percent_Identity=28, Blast_Score=125, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71995606, Length=447, Percent_Identity=28.4116331096197, Blast_Score=121, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71986308, Length=426, Percent_Identity=27.4647887323944, Blast_Score=119, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI71995613, Length=404, Percent_Identity=27.7227722772277, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71990744, Length=296, Percent_Identity=30.7432432432432, Blast_Score=103, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI25146391, Length=332, Percent_Identity=25.3012048192771, Blast_Score=91, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI32566756, Length=332, Percent_Identity=25.3012048192771, Blast_Score=90, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI25146394, Length=332, Percent_Identity=25.3012048192771, Blast_Score=90, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17564084, Length=334, Percent_Identity=25.748502994012, Blast_Score=89, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6321826, Length=537, Percent_Identity=29.0502793296089, Blast_Score=182, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6320917, Length=457, Percent_Identity=30.4157549234136, Blast_Score=165, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6324950, Length=448, Percent_Identity=27.2321428571429, Blast_Score=151, Evalue=5e-37,
Organism=Saccharomyces cerevisiae, GI6325196, Length=459, Percent_Identity=28.1045751633987, Blast_Score=150, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6323822, Length=475, Percent_Identity=28.4210526315789, Blast_Score=142, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6323821, Length=479, Percent_Identity=29.2275574112735, Blast_Score=139, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6319478, Length=412, Percent_Identity=28.1553398058252, Blast_Score=134, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6321828, Length=436, Percent_Identity=25.6880733944954, Blast_Score=92, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6323757, Length=325, Percent_Identity=25.2307692307692, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI281362580, Length=451, Percent_Identity=31.7073170731707, Blast_Score=176, Evalue=6e-44,
Organism=Drosophila melanogaster, GI62472918, Length=451, Percent_Identity=31.7073170731707, Blast_Score=176, Evalue=6e-44,
Organism=Drosophila melanogaster, GI62472926, Length=451, Percent_Identity=31.7073170731707, Blast_Score=176, Evalue=6e-44,
Organism=Drosophila melanogaster, GI62472936, Length=451, Percent_Identity=31.7073170731707, Blast_Score=176, Evalue=6e-44,
Organism=Drosophila melanogaster, GI21356737, Length=451, Percent_Identity=31.7073170731707, Blast_Score=176, Evalue=6e-44,
Organism=Drosophila melanogaster, GI24668425, Length=432, Percent_Identity=29.6296296296296, Blast_Score=176, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24668417, Length=432, Percent_Identity=29.6296296296296, Blast_Score=176, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24668413, Length=432, Percent_Identity=29.6296296296296, Blast_Score=176, Evalue=1e-43,
Organism=Drosophila melanogaster, GI20129399, Length=423, Percent_Identity=30.2600472813239, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24650465, Length=451, Percent_Identity=28.159645232816, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24666674, Length=429, Percent_Identity=27.2727272727273, Blast_Score=145, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24585660, Length=462, Percent_Identity=26.8398268398268, Blast_Score=143, Evalue=7e-34,
Organism=Drosophila melanogaster, GI28571802, Length=527, Percent_Identity=25.8064516129032, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI28571800, Length=527, Percent_Identity=25.8064516129032, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI28571806, Length=527, Percent_Identity=25.8064516129032, Blast_Score=135, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28571798, Length=527, Percent_Identity=25.8064516129032, Blast_Score=135, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28571796, Length=527, Percent_Identity=25.8064516129032, Blast_Score=135, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28571794, Length=527, Percent_Identity=25.8064516129032, Blast_Score=135, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28574525, Length=459, Percent_Identity=25.2723311546841, Blast_Score=119, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24638878, Length=425, Percent_Identity=26.8235294117647, Blast_Score=110, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24638876, Length=425, Percent_Identity=26.8235294117647, Blast_Score=110, Evalue=8e-24,
Organism=Drosophila melanogaster, GI281360301, Length=334, Percent_Identity=26.9461077844311, Blast_Score=97, Evalue=6e-20,
Organism=Drosophila melanogaster, GI281360299, Length=334, Percent_Identity=26.9461077844311, Blast_Score=97, Evalue=7e-20,
Organism=Drosophila melanogaster, GI281360297, Length=334, Percent_Identity=26.9461077844311, Blast_Score=97, Evalue=7e-20,
Organism=Drosophila melanogaster, GI281360295, Length=334, Percent_Identity=26.9461077844311, Blast_Score=97, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24586250, Length=334, Percent_Identity=26.9461077844311, Blast_Score=97, Evalue=7e-20,
Organism=Drosophila melanogaster, GI281360303, Length=334, Percent_Identity=26.3473053892216, Blast_Score=96, Evalue=2e-19,
Organism=Drosophila melanogaster, GI45552499, Length=334, Percent_Identity=26.3473053892216, Blast_Score=96, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 121812; Mature: 121681

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTAPFAAFAPRHSVPSDLRRAITAATRRAERECMVMLLPEATLPQATRASAQALARKL
CCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHH
VEALRAKPRGNGVEQLVQEYALSTHEGVALMCLAEALLRIPDNDTRDDLIRDKIAGGDWL
HHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHH
AHLGGDRSLFVNAATWGLVVTGKLASSVDDTGLGAALTRLIARAGEPVIRRGVDLAMRMM
HHCCCCCEEEEEEEEECEEEECHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHH
GEQFVTGETIDEALKRARPLEDRGFRYSYDMLGEAAMTASDAARYHADYQAAIHAIGKAA
HHHHCCCHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARRGVYEGPGISIKLSALHPRYARAQQDRVFAELLPRLKALAYLALRYDIGLNIDAEEAD
HHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHH
RLELSLDLLEELAMDPELAGWNGLGFVVQAYGKRCPFVIDWIVDLARRSGRRIMVRLVKG
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEHHHHHC
AYWDAEIKRAQVDGQSGFPVYTRKAHTDVAYIACARRLLAATDVVFPQFATHNAQTLATI
CCCCHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHH
HEMAGPDFAVGRYEFQCLHGMGEPLYDEVVGKDKLDRPCRIYAPVGTHETLLAYLVRRLL
HHHCCCCEECCCHHHHHHHCCCCHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHH
ENGANSSFVNRIANPDVPVDEIVADPVAQVAADADPGAPHPLIALPAALYPDRRNSSGLD
HCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEECCHHHCCCCCCCCCCC
LADESTLAALTDRFQAISAHSRHAHPSADLPHVNPRPVLNPANHRDVVGHVSEAAPAAAG
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCHHHHH
MAASLAAASRWSATPVAARAMILERAADAMQAAMPELIALIVREAGKSVSNAIAEVREAV
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
DFLRYYASQAPAMSGSRPLGVALCISPWNFPLAIFTGQVAAALMAGNPVLAKPAEETPLI
HHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEECCCCCCCCH
ASEAVRILHEAGVPDDALVFLPGDGAIGAALVAAPEIAAVLFTGSTEVGRLIQRQLATRL
HHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHH
SAEGRPIPLIAETGGQNAMIVDSSALAEQVVADVIASAFDSAGQRCSALRVLCLQEDVAD
CCCCCCEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HVLAMLRGALAELTVGPTDRLSADIGPVIAAEAREAIEAHVARMEAAGCPVHRLPLGTAT
HHHHHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCC
NEGTFVAPTIIELSAPDLLTREVFGPVLHVIRFRRADMDAMVERINAWGYGLTFGLHTRL
CCCCEEECEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEHHHHHH
DETVARVTAKAHAGNIYVNRNVIGAVVGVQPFGGHGLSGTGPKAGGPLYLRRLVASAPAA
HHHHHHHHHHHCCCEEEEECCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCC
PALELTERELPGPVGERNIYALRPVGRVLVAAQSPERLAALTSRVERLGGTPIAADDGWQ
CCHHHHHHHCCCCCCCCCEEEECCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCC
AQGPFARALVEGDAAFILSFQQAVAALDGPIAPVLASADDDTMLVAEVSLSINTTAAGGN
CCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHEECCCCCEEEEEEEEEEEEEECCCCC
ASLMAMA
CEEEEEC
>Mature Secondary Structure 
TQTAPFAAFAPRHSVPSDLRRAITAATRRAERECMVMLLPEATLPQATRASAQALARKL
CCCCCCHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHH
VEALRAKPRGNGVEQLVQEYALSTHEGVALMCLAEALLRIPDNDTRDDLIRDKIAGGDWL
HHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHH
AHLGGDRSLFVNAATWGLVVTGKLASSVDDTGLGAALTRLIARAGEPVIRRGVDLAMRMM
HHCCCCCEEEEEEEEECEEEECHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHH
GEQFVTGETIDEALKRARPLEDRGFRYSYDMLGEAAMTASDAARYHADYQAAIHAIGKAA
HHHHCCCHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARRGVYEGPGISIKLSALHPRYARAQQDRVFAELLPRLKALAYLALRYDIGLNIDAEEAD
HHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHH
RLELSLDLLEELAMDPELAGWNGLGFVVQAYGKRCPFVIDWIVDLARRSGRRIMVRLVKG
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEHHHHHC
AYWDAEIKRAQVDGQSGFPVYTRKAHTDVAYIACARRLLAATDVVFPQFATHNAQTLATI
CCCCHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHH
HEMAGPDFAVGRYEFQCLHGMGEPLYDEVVGKDKLDRPCRIYAPVGTHETLLAYLVRRLL
HHHCCCCEECCCHHHHHHHCCCCHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHH
ENGANSSFVNRIANPDVPVDEIVADPVAQVAADADPGAPHPLIALPAALYPDRRNSSGLD
HCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEECCHHHCCCCCCCCCCC
LADESTLAALTDRFQAISAHSRHAHPSADLPHVNPRPVLNPANHRDVVGHVSEAAPAAAG
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCHHHHH
MAASLAAASRWSATPVAARAMILERAADAMQAAMPELIALIVREAGKSVSNAIAEVREAV
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
DFLRYYASQAPAMSGSRPLGVALCISPWNFPLAIFTGQVAAALMAGNPVLAKPAEETPLI
HHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEECCCCCCCCH
ASEAVRILHEAGVPDDALVFLPGDGAIGAALVAAPEIAAVLFTGSTEVGRLIQRQLATRL
HHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHH
SAEGRPIPLIAETGGQNAMIVDSSALAEQVVADVIASAFDSAGQRCSALRVLCLQEDVAD
CCCCCCEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HVLAMLRGALAELTVGPTDRLSADIGPVIAAEAREAIEAHVARMEAAGCPVHRLPLGTAT
HHHHHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCC
NEGTFVAPTIIELSAPDLLTREVFGPVLHVIRFRRADMDAMVERINAWGYGLTFGLHTRL
CCCCEEECEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEHHHHHH
DETVARVTAKAHAGNIYVNRNVIGAVVGVQPFGGHGLSGTGPKAGGPLYLRRLVASAPAA
HHHHHHHHHHHCCCEEEEECCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCC
PALELTERELPGPVGERNIYALRPVGRVLVAAQSPERLAALTSRVERLGGTPIAADDGWQ
CCHHHHHHHCCCCCCCCCEEEECCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCC
AQGPFARALVEGDAAFILSFQQAVAALDGPIAPVLASADDDTMLVAEVSLSINTTAAGGN
CCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHEECCCCCEEEEEEEEEEEEEECCCCC
ASLMAMA
CEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9004223; 10715000 [H]