BacMap

Definition	Novosphingobium aromaticivorans DSM 12444 chromosome, complete genome.
Accession	NC_007794
Length	3,561,584

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The map label for this gene is ligD [H]

Identifier: 87198727

GI number: 87198727

Start: 742296

End: 743213

Strand: Reverse

Name: ligD [H]

Synonym: Saro_0703

Alternate gene names: 87198727

Gene position: 743213-742296 (Counterclockwise)

Preceding gene: 87198728

Following gene: 87198725

Centisome position: 20.87

GC content: 65.36

Gene sequence:

>918_bases
ATGACTGGCAGTACACGTGATTTCACAGGCAAGACCGCGTTCATTACCGGCGGCGTCAACGGCATAGGCTTCGGCATTGC
GCGGGCTTTCGCGCTCGCGGGCATGGATCTCATCCTCACCTACCGCAAGGACGAGGACCGCGACGACGCCGCCCGTTGGC
TGGCTGACAACGGCCTTGCCCCCGCCCGCTTCGTCCGTCTCGACGTGACCGACCGCGCCCGGTTCGCGCAAGTCGCCGCC
GAAGTTGGAAAGGTCCACGTTCTCGTCAACAACGCAGGCGTCAGCGTCTTCGGTCCCACCGACGAGGCCAGCTATGACGA
CTACGACTGGATCATGGGGGTGAACTTCGGTGGCGTGGTCAACGGCCTCGTCTCCTTCCTGCCGGGCATGAAGGCCCATG
GCGAGGGTGGCCACGTGGTAAACGTCGCCTCGATGGCGGCCTACCTTTCGGGGCCACAGGCAGGCATCTACACCGCCAGC
AAGTTCGCGGTGCGCGGCCTGACAGAATGCCTGCGCTACAACCTCGCCCCGCACGGCATCGGCGTTTCCCTGATGTGCCC
CGGCCTGACCCGCACCAACGCCTGGACCAGCGCGCTCAAGCGCCCGGACAGTTTCGCCGAATCGGGCTTCAAGCCCGCAG
ACGCCACCGAGCTGGAACAGTTCGGCACCGCATTCGAGCTGGGCATGGACCCGTTTGAGGTCGGGCAAAAGACGCTCGCC
GGCATGATCGAGAACCGTGGCCTCATCCTGACCCACGGCGAATTCGCCGACGACTTCGAGGAGATCTATCGCACGTCGCT
CGCGGCACTACCGCAGGAGGTTATCCCCGAGGGGCGCCTGCACATCGAAGCCTTGCGCCGCGCGGCCAACAAGGCGGCAG
CAGAAGGGCAGCAGATCGGCCTTGCCGACCTCACCTGA

Upstream 100 bases:

>100_bases
CAACGCCAGCCTGATGGCCATGGCCTGATGCCGTTTCACTTGCGCCGGTTGCCCGCATTCCTCCCAATTGTTAGGCTGCC
AAACGGAAGAGGAATGACAC

Downstream 100 bases:

>100_bases
CGCACCACAGAAAAAGGGGGCACCGGGTGCTGTGCCCGGCGCCCCCCGATAGGGTCATGCGTCTCATCCTGCAGCAACAA
CTCGGCCGTTGCCGCGCGGG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MTGSTRDFTGKTAFITGGVNGIGFGIARAFALAGMDLILTYRKDEDRDDAARWLADNGLAPARFVRLDVTDRARFAQVAA
EVGKVHVLVNNAGVSVFGPTDEASYDDYDWIMGVNFGGVVNGLVSFLPGMKAHGEGGHVVNVASMAAYLSGPQAGIYTAS
KFAVRGLTECLRYNLAPHGIGVSLMCPGLTRTNAWTSALKRPDSFAESGFKPADATELEQFGTAFELGMDPFEVGQKTLA
GMIENRGLILTHGEFADDFEEIYRTSLAALPQEVIPEGRLHIEALRRAANKAAAEGQQIGLADLT

Sequences:

>Translated_305_residues
MTGSTRDFTGKTAFITGGVNGIGFGIARAFALAGMDLILTYRKDEDRDDAARWLADNGLAPARFVRLDVTDRARFAQVAA
EVGKVHVLVNNAGVSVFGPTDEASYDDYDWIMGVNFGGVVNGLVSFLPGMKAHGEGGHVVNVASMAAYLSGPQAGIYTAS
KFAVRGLTECLRYNLAPHGIGVSLMCPGLTRTNAWTSALKRPDSFAESGFKPADATELEQFGTAFELGMDPFEVGQKTLA
GMIENRGLILTHGEFADDFEEIYRTSLAALPQEVIPEGRLHIEALRRAANKAAAEGQQIGLADLT
>Mature_304_residues
TGSTRDFTGKTAFITGGVNGIGFGIARAFALAGMDLILTYRKDEDRDDAARWLADNGLAPARFVRLDVTDRARFAQVAAE
VGKVHVLVNNAGVSVFGPTDEASYDDYDWIMGVNFGGVVNGLVSFLPGMKAHGEGGHVVNVASMAAYLSGPQAGIYTASK
FAVRGLTECLRYNLAPHGIGVSLMCPGLTRTNAWTSALKRPDSFAESGFKPADATELEQFGTAFELGMDPFEVGQKTLAG
MIENRGLILTHGEFADDFEEIYRTSLAALPQEVIPEGRLHIEALRRAANKAAAEGQQIGLADLT

Specific function: Catalyzes the C alpha dehydrogenation of arylglycerol- beta-aryl ether (C alpha alcohol type) (compound IV) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=198, Percent_Identity=33.3333333333333, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI20149619, Length=237, Percent_Identity=29.535864978903, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI5031737, Length=190, Percent_Identity=35.2631578947368, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=35.2631578947368, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI7706318, Length=195, Percent_Identity=31.7948717948718, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI44680136, Length=188, Percent_Identity=30.3191489361702, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI44680133, Length=188, Percent_Identity=30.3191489361702, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI17738292, Length=188, Percent_Identity=30.3191489361702, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI223718074, Length=197, Percent_Identity=34.010152284264, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI40548397, Length=195, Percent_Identity=35.8974358974359, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI214010158, Length=195, Percent_Identity=35.8974358974359, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI214010156, Length=195, Percent_Identity=35.8974358974359, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI22758144, Length=195, Percent_Identity=35.8974358974359, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI126723191, Length=206, Percent_Identity=31.0679611650485, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI31542939, Length=207, Percent_Identity=29.4685990338164, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI157739938, Length=239, Percent_Identity=28.0334728033473, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI7705925, Length=186, Percent_Identity=28.494623655914, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI4758504, Length=224, Percent_Identity=28.125, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI66933014, Length=164, Percent_Identity=28.6585365853659, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI7657478, Length=185, Percent_Identity=32.972972972973, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI126723750, Length=202, Percent_Identity=27.2277227722772, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI142976729, Length=284, Percent_Identity=27.4647887323944, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI4503817, Length=228, Percent_Identity=25.4385964912281, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI224922801, Length=170, Percent_Identity=30, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI87082100, Length=238, Percent_Identity=33.6134453781513, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788459, Length=226, Percent_Identity=29.646017699115, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI2367365, Length=189, Percent_Identity=34.9206349206349, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786812, Length=234, Percent_Identity=29.9145299145299, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1789208, Length=194, Percent_Identity=30.9278350515464, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787820, Length=238, Percent_Identity=30.672268907563, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786701, Length=185, Percent_Identity=32.4324324324324, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1790717, Length=203, Percent_Identity=30.5418719211823, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787335, Length=194, Percent_Identity=28.8659793814433, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082160, Length=202, Percent_Identity=25.2475247524752, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=190, Percent_Identity=32.6315789473684, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=214, Percent_Identity=31.3084112149533, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=224, Percent_Identity=27.6785714285714, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17561402, Length=198, Percent_Identity=28.7878787878788, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=283, Percent_Identity=27.5618374558304, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17560676, Length=202, Percent_Identity=27.2277227722772, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17567345, Length=195, Percent_Identity=30.7692307692308, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=199, Percent_Identity=29.1457286432161, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=207, Percent_Identity=30.4347826086957, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=200, Percent_Identity=31.5, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI115534660, Length=198, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17557780, Length=137, Percent_Identity=34.3065693430657, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17538182, Length=211, Percent_Identity=30.3317535545024, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=214, Percent_Identity=28.5046728971963, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=209, Percent_Identity=29.1866028708134, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=197, Percent_Identity=27.9187817258883, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=200, Percent_Identity=30, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=204, Percent_Identity=31.3725490196078, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17507613, Length=197, Percent_Identity=28.9340101522843, Blast_Score=64, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=195, Percent_Identity=29.7435897435897, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=192, Percent_Identity=30.7291666666667, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356301, Length=200, Percent_Identity=30.5, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21358495, Length=252, Percent_Identity=26.984126984127, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21355319, Length=247, Percent_Identity=29.1497975708502, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21355631, Length=174, Percent_Identity=31.6091954022989, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24644339, Length=191, Percent_Identity=31.413612565445, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24640442, Length=221, Percent_Identity=29.8642533936652, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI28571526, Length=191, Percent_Identity=29.3193717277487, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21357041, Length=190, Percent_Identity=29.4736842105263, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24643142, Length=189, Percent_Identity=31.2169312169312, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24665247, Length=208, Percent_Identity=26.4423076923077, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI161076933, Length=190, Percent_Identity=30.5263157894737, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24584748, Length=190, Percent_Identity=30.5263157894737, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221331216, Length=201, Percent_Identity=27.363184079602, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24665243, Length=208, Percent_Identity=26.9230769230769, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221331218, Length=201, Percent_Identity=27.8606965174129, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI23397609, Length=189, Percent_Identity=30.6878306878307, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28574402, Length=197, Percent_Identity=28.9340101522843, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24584744, Length=197, Percent_Identity=28.9340101522843, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24584752, Length=200, Percent_Identity=26.5, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24663911, Length=205, Percent_Identity=29.7560975609756, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24581726, Length=219, Percent_Identity=29.6803652968037, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI116007236, Length=194, Percent_Identity=28.3505154639175, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 32538; Mature: 32407

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGSTRDFTGKTAFITGGVNGIGFGIARAFALAGMDLILTYRKDEDRDDAARWLADNGLA
CCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHCCCCC
PARFVRLDVTDRARFAQVAAEVGKVHVLVNNAGVSVFGPTDEASYDDYDWIMGVNFGGVV
CEEEEEEECCHHHHHHHHHHHHCEEEEEEECCCEEEECCCCCCCCCCCCEEEECCHHHHH
NGLVSFLPGMKAHGEGGHVVNVASMAAYLSGPQAGIYTASKFAVRGLTECLRYNLAPHGI
HHHHHHCCCCCCCCCCCCEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
GVSLMCPGLTRTNAWTSALKRPDSFAESGFKPADATELEQFGTAFELGMDPFEVGQKTLA
CEEEECCCCCCCHHHHHHHCCCHHHHHCCCCCCCHHHHHHHCCHHHCCCCHHHHHHHHHH
GMIENRGLILTHGEFADDFEEIYRTSLAALPQEVIPEGRLHIEALRRAANKAAAEGQQIG
HHHHCCCEEEECCCHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHCCCCCC
LADLT
CCCCC
>Mature Secondary Structure 
TGSTRDFTGKTAFITGGVNGIGFGIARAFALAGMDLILTYRKDEDRDDAARWLADNGLA
CCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHCCCCC
PARFVRLDVTDRARFAQVAAEVGKVHVLVNNAGVSVFGPTDEASYDDYDWIMGVNFGGVV
CEEEEEEECCHHHHHHHHHHHHCEEEEEEECCCEEEECCCCCCCCCCCCEEEECCHHHHH
NGLVSFLPGMKAHGEGGHVVNVASMAAYLSGPQAGIYTASKFAVRGLTECLRYNLAPHGI
HHHHHHCCCCCCCCCCCCEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
GVSLMCPGLTRTNAWTSALKRPDSFAESGFKPADATELEQFGTAFELGMDPFEVGQKTLA
CEEEECCCCCCCHHHHHHHCCCHHHHHCCCCCCCHHHHHHHCCHHHCCCCHHHHHHHHHH
GMIENRGLILTHGEFADDFEEIYRTSLAALPQEVIPEGRLHIEALRRAANKAAAEGQQIG
HHHHCCCEEEECCCHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHCCCCCC
LADLT
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1744051; 8495726; 7764263 [H]