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The map label for this gene is gap [H]

Identifier: 86751565

GI number: 86751565

Start: 5058132

End: 5059139

Strand: Direct

Name: gap [H]

Synonym: RPB_4467

Alternate gene names: 86751565

Gene position: 5058132-5059139 (Clockwise)

Preceding gene: 86751564

Following gene: 86751566

Centisome position: 94.87

GC content: 64.68

Gene sequence:

>1008_bases
ATGGCAGTCCGGGTCGCGATCAATGGGTTTGGCCGTATCGGCCGCAACGTGCTGCGGGCGATCTACGAATCCGGCCGTAA
GGACATCGAGGTCGTCGCGATCAACGATCTCGGCCCGGTCGAGACCAACGCCCATCTGCTCCGCTTCGACTCCGTGCACG
GCCGCTTCCCGTTCGAGGTCAAGGTCGACGGCGACACCATCGACATCGGCCGCGGCAAGATCAAGGTCACGGCGATCAAG
GACCCGTCGGCGCTGCCCTATAAGGACGTCGGCGTCGACATCGCGATGGAATGCACCGGCATCTTCACCGCGCGCGACAA
GGCCGCGACGCTGCTGACCGCCGGCGCCAAGCGCGTGCTGGTCTCGGCGCCGTCGGACGGCGCCGATGCGACCATCGTCT
ATGGCGTCAACCACGAGACCCTCTCGAAGGACCACATGGTGGTGTCGAACGGCTCGTGCACGACCAACTGCCTCGCCCCG
GTCGCCAAGGTGCTGAACGACACCGTCGGCATCGAGACCGGCTTCATGACCACCATCCACGCCTACACCGGCGACCAGCC
GACGCTGGATACGATGCACAAGGATCTGTATCGCGGCCGCGCCGCGGCGATGTCGATGATCCCGACCTCGACCGGCGCCG
CCAAGGCGATCGGCCTGGTGCTGCCCGAACTGAAGGGCAAGCTCGACGGCGTCGCGATCCGCGTGCCGACCCCGAACGTC
TCGGTGGTCGACCTCAAGATCATCGCCAAGCGCGCCACCACCAAGGAAGAGATCAACGAGGCGATGAAGCGCGCCGCCGA
TCAGGAGCTCAAGGGCATCCTCGGCTACACCTTCGCGCCCAACGTCTCGATCGACTTCAACCACGATCCGCATTCGTCGA
CCTTCCACATGGACCAGACCAAGGTGCAGAACGGCACGCTGGTGCGGGTGATGTCCTGGTACGACAACGAATGGGGCTTC
TCGAACCGCATGGCCGATACGGCTGTCGCGATGAGCAAGCTGATCTGA

Upstream 100 bases:

>100_bases
GCGGATTGCAACCGCTCGGTATTCAGGGCATGAAACCGCACAAGTACGGGGGTCGCCCCGTCGCAACAATTGAAAATCAC
GAGCAGCGAGGAGAATTTGG

Downstream 100 bases:

>100_bases
GTTACTTGTCCCGGGCGCAGCGCAGCACGACGTGATGCGCTGCTGAACCGGGACCGTATCGTTTGTGGCGGTCCCGGCTC
AGCGGTGCACCGCTTCGCGC

Product: glyceraldehyde-3-phosphate dehydrogenase, type I

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MAVRVAINGFGRIGRNVLRAIYESGRKDIEVVAINDLGPVETNAHLLRFDSVHGRFPFEVKVDGDTIDIGRGKIKVTAIK
DPSALPYKDVGVDIAMECTGIFTARDKAATLLTAGAKRVLVSAPSDGADATIVYGVNHETLSKDHMVVSNGSCTTNCLAP
VAKVLNDTVGIETGFMTTIHAYTGDQPTLDTMHKDLYRGRAAAMSMIPTSTGAAKAIGLVLPELKGKLDGVAIRVPTPNV
SVVDLKIIAKRATTKEEINEAMKRAADQELKGILGYTFAPNVSIDFNHDPHSSTFHMDQTKVQNGTLVRVMSWYDNEWGF
SNRMADTAVAMSKLI

Sequences:

>Translated_335_residues
MAVRVAINGFGRIGRNVLRAIYESGRKDIEVVAINDLGPVETNAHLLRFDSVHGRFPFEVKVDGDTIDIGRGKIKVTAIK
DPSALPYKDVGVDIAMECTGIFTARDKAATLLTAGAKRVLVSAPSDGADATIVYGVNHETLSKDHMVVSNGSCTTNCLAP
VAKVLNDTVGIETGFMTTIHAYTGDQPTLDTMHKDLYRGRAAAMSMIPTSTGAAKAIGLVLPELKGKLDGVAIRVPTPNV
SVVDLKIIAKRATTKEEINEAMKRAADQELKGILGYTFAPNVSIDFNHDPHSSTFHMDQTKVQNGTLVRVMSWYDNEWGF
SNRMADTAVAMSKLI
>Mature_334_residues
AVRVAINGFGRIGRNVLRAIYESGRKDIEVVAINDLGPVETNAHLLRFDSVHGRFPFEVKVDGDTIDIGRGKIKVTAIKD
PSALPYKDVGVDIAMECTGIFTARDKAATLLTAGAKRVLVSAPSDGADATIVYGVNHETLSKDHMVVSNGSCTTNCLAPV
AKVLNDTVGIETGFMTTIHAYTGDQPTLDTMHKDLYRGRAAAMSMIPTSTGAAKAIGLVLPELKGKLDGVAIRVPTPNVS
VVDLKIIAKRATTKEEINEAMKRAADQELKGILGYTFAPNVSIDFNHDPHSSTFHMDQTKVQNGTLVRVMSWYDNEWGFS
NRMADTAVAMSKLI

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=333, Percent_Identity=48.048048048048, Blast_Score=292, Evalue=4e-79,
Organism=Homo sapiens, GI7657116, Length=326, Percent_Identity=45.398773006135, Blast_Score=264, Evalue=7e-71,
Organism=Escherichia coli, GI1789295, Length=334, Percent_Identity=47.6047904191617, Blast_Score=337, Evalue=5e-94,
Organism=Escherichia coli, GI1788079, Length=335, Percent_Identity=50.4477611940299, Blast_Score=307, Evalue=7e-85,
Organism=Caenorhabditis elegans, GI17534677, Length=332, Percent_Identity=50.3012048192771, Blast_Score=297, Evalue=5e-81,
Organism=Caenorhabditis elegans, GI17534679, Length=332, Percent_Identity=50, Blast_Score=296, Evalue=7e-81,
Organism=Caenorhabditis elegans, GI32566163, Length=332, Percent_Identity=48.1927710843374, Blast_Score=278, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI17568413, Length=332, Percent_Identity=48.1927710843374, Blast_Score=278, Evalue=2e-75,
Organism=Saccharomyces cerevisiae, GI6321631, Length=328, Percent_Identity=50, Blast_Score=297, Evalue=2e-81,
Organism=Saccharomyces cerevisiae, GI6322468, Length=328, Percent_Identity=49.390243902439, Blast_Score=296, Evalue=4e-81,
Organism=Saccharomyces cerevisiae, GI6322409, Length=328, Percent_Identity=48.780487804878, Blast_Score=295, Evalue=5e-81,
Organism=Drosophila melanogaster, GI85725000, Length=326, Percent_Identity=49.3865030674847, Blast_Score=286, Evalue=1e-77,
Organism=Drosophila melanogaster, GI22023983, Length=326, Percent_Identity=49.3865030674847, Blast_Score=286, Evalue=1e-77,
Organism=Drosophila melanogaster, GI17933600, Length=326, Percent_Identity=49.3865030674847, Blast_Score=286, Evalue=1e-77,
Organism=Drosophila melanogaster, GI18110149, Length=326, Percent_Identity=49.3865030674847, Blast_Score=286, Evalue=1e-77,
Organism=Drosophila melanogaster, GI19922412, Length=326, Percent_Identity=44.7852760736196, Blast_Score=261, Evalue=6e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36116; Mature: 35985

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVRVAINGFGRIGRNVLRAIYESGRKDIEVVAINDLGPVETNAHLLRFDSVHGRFPFEV
CEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCCCEEE
KVDGDTIDIGRGKIKVTAIKDPSALPYKDVGVDIAMECTGIFTARDKAATLLTAGAKRVL
EECCCEEEECCCEEEEEEECCCCCCCHHHCCEEEEEEEEEEEEECCCHHHEEECCCCEEE
VSAPSDGADATIVYGVNHETLSKDHMVVSNGSCTTNCLAPVAKVLNDTVGIETGFMTTIH
EECCCCCCCEEEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEE
AYTGDQPTLDTMHKDLYRGRAAAMSMIPTSTGAAKAIGLVLPELKGKLDGVAIRVPTPNV
EECCCCCCHHHHHHHHHHCHHHHHEECCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCC
SVVDLKIIAKRATTKEEINEAMKRAADQELKGILGYTFAPNVSIDFNHDPHSSTFHMDQT
EEEEEEEEEHHCCCHHHHHHHHHHHHHHHHHHHCCEEECCCEEEECCCCCCCCEEECCHH
KVQNGTLVRVMSWYDNEWGFSNRMADTAVAMSKLI
CCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
AVRVAINGFGRIGRNVLRAIYESGRKDIEVVAINDLGPVETNAHLLRFDSVHGRFPFEV
EEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCCCEEE
KVDGDTIDIGRGKIKVTAIKDPSALPYKDVGVDIAMECTGIFTARDKAATLLTAGAKRVL
EECCCEEEECCCEEEEEEECCCCCCCHHHCCEEEEEEEEEEEEECCCHHHEEECCCCEEE
VSAPSDGADATIVYGVNHETLSKDHMVVSNGSCTTNCLAPVAKVLNDTVGIETGFMTTIH
EECCCCCCCEEEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEE
AYTGDQPTLDTMHKDLYRGRAAAMSMIPTSTGAAKAIGLVLPELKGKLDGVAIRVPTPNV
EECCCCCCHHHHHHHHHHCHHHHHEECCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCC
SVVDLKIIAKRATTKEEINEAMKRAADQELKGILGYTFAPNVSIDFNHDPHSSTFHMDQT
EEEEEEEEEHHCCCHHHHHHHHHHHHHHHHHHHCCEEECCCEEEECCCCCCCCEEECCHH
KVQNGTLVRVMSWYDNEWGFSNRMADTAVAMSKLI
CCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7928974 [H]