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The map label for this gene is cbbT [H]

Identifier: 86751564

GI number: 86751564

Start: 5056019

End: 5058007

Strand: Direct

Name: cbbT [H]

Synonym: RPB_4466

Alternate gene names: 86751564

Gene position: 5056019-5058007 (Clockwise)

Preceding gene: 86751561

Following gene: 86751565

Centisome position: 94.83

GC content: 67.72

Gene sequence:

>1989_bases
ATGGCGAAGGTCGATCATTCCCGTATGGCGAACGCAATCCGGGCGCTGGCGATGGACGCGGTCGAGAAGGCCAAATCCGG
CCACCCCGGCCTGCCGATGGGCGCCGCCGACGTCGCCACAGTGCTGTTCACCGAGTTCCTGAAATTCGACGCCGCCGATG
CGCACTGGCCGGATCGCGACCGCTTCATCCTGTCCGCCGGCCACGGCTCGATGCTGCTCTATGCGCTGTTGTACCTCACC
GGTAATTCCGAGCTGACGCTCGACCAGATCAAGGCGTTCCGCCAGCTCGACTCCAAGACGCCCGGGCACCCGGAGAACTG
CATCACAGATTCGGTTGAAACCACCACCGGCCCGCTCGGCCAGGGCGTGGCGTCGTCGGTCGGCACCGCGCTGGCGGAGC
GTCTGCTCGCCGCCGAATTCGGCGAGATCGTCGATCACACCACCTACGTGCTGTGCTCGGACGGCGATCTGATGGAAGGC
GTGAGCCACGAGGCGATCGCGCTGGCCGGCCATCTCAGGCTGTCGAAGCTGATCTTCCTCTACGACGACAACGGCATCTC
GATCGACGGCCCGCTGACGCTGACCGACAATGTCGATCAGGTCGCGCGCTTCCAGGCGCATGGCTGGAATGCGATGCGGA
TCGACGGCCACGATCACAAGGCGATCGCCGAGGCGATCAAGGCCGCGAAAGCCTCCGACCGGCCGACCATGATCGCCTGC
AAGACCACGATCGGCTTCGGCGCCCCCACCCGGGCCGGGACCTCCAAGGCGCATGGCGAGCCGCTCGGCGCCGAAGAACT
GGCCGGCGCCAAGAAGGCGCTGGGCTGGGACTACGGCCCGTTCGAAATTCCGGACGACGTGCTCTCCGCTTGGCGCGCGG
TCGGCGCCAAGGGCGCCAAGGCCCACGCGGAATGGCAGTCGAAGTTCGACGCGATGGACAAGGAGCTGCGCGCCGAATTC
CAGCGCCGGGTGATCGACCGCAAGCGGCCGGCGGCGCTCGACGGCGCGATCCGCAAGCTCAAGGACAGGCTCGTCGCGGA
GCCGCAGACCATCGCCACCCGCAAGGCCAGCGAGCTGGCGCTGGAGGCCATCGTCGAGGTGGTGCCGGAAATGCTGCTCG
GCTCGGCGGACCTGACGCCGTCCAACAACACCCGCACCAAACACGCGAAAGACGTCACCCCGGACGACTTCTCGGGTCGC
TACATCCATTACGGCATCCGCGAAATGGGCATGGCGGCGGCGATGAACGGTATCGCGATGCATGGCGGTTTCGCGCCGGC
CGGCGGCACCTTCATGTGCTTCGCCGACTACGCCCGCCCGTCGATGCGGATCGCGGCGCTGTCGCATGTCCCGGTGGTCT
ACATCATGACCCATGATTCGATCGGGCTCGGCGAAGACGGCCCGACGCATCAGCCGGTCGAGCACCTCGCTTCGCTGCGG
GCGATGCCCAATATGCGGGTGTTCCGCCCGGCCGACCCGGTCGAGACCGCCGAATGCTGGCAGCTCGCGCTGGAGAACAC
CAAGGGCCCGACGGTGCTGGCGCTGTCGCGGCAGAATCTGACGCCGGTGCGCACCAGCAAATCCGACGACAACCGCTGCG
CCCGGGGCGCCTATGAGCTGATCGCCGCCGACGGCAAGGCTCAGGTGACGATCTTCGCCACCGGCTCCGAGGTCGAGATC
GCGGTCGCGGCGCACAAGCTGCTCGCCGCCAAGGGCATCGCTGCGCGCGTGGTGTCGGTGCCGTCGCTGGATCTCTTGCT
GCAGCAGGACGACGCCACCCGCAAGGCGATCATCGGCGACGCCCCGGTCAAGGTCGCGGTCGAGGCCGCGGTGCGGTTCG
GCTGGGACGCGGTGATCGGCCCGGAGGGCGGCTTCATCGGCATGTCGAGCTTCGGCGCCAGCGCGCCCGCGAAGGATCTG
TACAAGCATTTCGGAATTACCGCCGAGGCGGTCGCAGAGGCTGCGGCAAGCCGTCTCGGCGGCAAGTAA

Upstream 100 bases:

>100_bases
CCGGTACTCTCGGCCTTATCGCATGTCTGGCTGAGCCGGACCGACAGCGCGTTCCGGCTCGCGGAACGCCGGCAAACACA
CGATTTCAGGTGGTTACATC

Downstream 100 bases:

>100_bases
GGCTTTGATCTGAATCATGAACGAGCGGATTGCAACCGCTCGGTATTCAGGGCATGAAACCGCACAAGTACGGGGGTCGC
CCCGTCGCAACAATTGAAAA

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 662; Mature: 661

Protein sequence:

>662_residues
MAKVDHSRMANAIRALAMDAVEKAKSGHPGLPMGAADVATVLFTEFLKFDAADAHWPDRDRFILSAGHGSMLLYALLYLT
GNSELTLDQIKAFRQLDSKTPGHPENCITDSVETTTGPLGQGVASSVGTALAERLLAAEFGEIVDHTTYVLCSDGDLMEG
VSHEAIALAGHLRLSKLIFLYDDNGISIDGPLTLTDNVDQVARFQAHGWNAMRIDGHDHKAIAEAIKAAKASDRPTMIAC
KTTIGFGAPTRAGTSKAHGEPLGAEELAGAKKALGWDYGPFEIPDDVLSAWRAVGAKGAKAHAEWQSKFDAMDKELRAEF
QRRVIDRKRPAALDGAIRKLKDRLVAEPQTIATRKASELALEAIVEVVPEMLLGSADLTPSNNTRTKHAKDVTPDDFSGR
YIHYGIREMGMAAAMNGIAMHGGFAPAGGTFMCFADYARPSMRIAALSHVPVVYIMTHDSIGLGEDGPTHQPVEHLASLR
AMPNMRVFRPADPVETAECWQLALENTKGPTVLALSRQNLTPVRTSKSDDNRCARGAYELIAADGKAQVTIFATGSEVEI
AVAAHKLLAAKGIAARVVSVPSLDLLLQQDDATRKAIIGDAPVKVAVEAAVRFGWDAVIGPEGGFIGMSSFGASAPAKDL
YKHFGITAEAVAEAAASRLGGK

Sequences:

>Translated_662_residues
MAKVDHSRMANAIRALAMDAVEKAKSGHPGLPMGAADVATVLFTEFLKFDAADAHWPDRDRFILSAGHGSMLLYALLYLT
GNSELTLDQIKAFRQLDSKTPGHPENCITDSVETTTGPLGQGVASSVGTALAERLLAAEFGEIVDHTTYVLCSDGDLMEG
VSHEAIALAGHLRLSKLIFLYDDNGISIDGPLTLTDNVDQVARFQAHGWNAMRIDGHDHKAIAEAIKAAKASDRPTMIAC
KTTIGFGAPTRAGTSKAHGEPLGAEELAGAKKALGWDYGPFEIPDDVLSAWRAVGAKGAKAHAEWQSKFDAMDKELRAEF
QRRVIDRKRPAALDGAIRKLKDRLVAEPQTIATRKASELALEAIVEVVPEMLLGSADLTPSNNTRTKHAKDVTPDDFSGR
YIHYGIREMGMAAAMNGIAMHGGFAPAGGTFMCFADYARPSMRIAALSHVPVVYIMTHDSIGLGEDGPTHQPVEHLASLR
AMPNMRVFRPADPVETAECWQLALENTKGPTVLALSRQNLTPVRTSKSDDNRCARGAYELIAADGKAQVTIFATGSEVEI
AVAAHKLLAAKGIAARVVSVPSLDLLLQQDDATRKAIIGDAPVKVAVEAAVRFGWDAVIGPEGGFIGMSSFGASAPAKDL
YKHFGITAEAVAEAAASRLGGK
>Mature_661_residues
AKVDHSRMANAIRALAMDAVEKAKSGHPGLPMGAADVATVLFTEFLKFDAADAHWPDRDRFILSAGHGSMLLYALLYLTG
NSELTLDQIKAFRQLDSKTPGHPENCITDSVETTTGPLGQGVASSVGTALAERLLAAEFGEIVDHTTYVLCSDGDLMEGV
SHEAIALAGHLRLSKLIFLYDDNGISIDGPLTLTDNVDQVARFQAHGWNAMRIDGHDHKAIAEAIKAAKASDRPTMIACK
TTIGFGAPTRAGTSKAHGEPLGAEELAGAKKALGWDYGPFEIPDDVLSAWRAVGAKGAKAHAEWQSKFDAMDKELRAEFQ
RRVIDRKRPAALDGAIRKLKDRLVAEPQTIATRKASELALEAIVEVVPEMLLGSADLTPSNNTRTKHAKDVTPDDFSGRY
IHYGIREMGMAAAMNGIAMHGGFAPAGGTFMCFADYARPSMRIAALSHVPVVYIMTHDSIGLGEDGPTHQPVEHLASLRA
MPNMRVFRPADPVETAECWQLALENTKGPTVLALSRQNLTPVRTSKSDDNRCARGAYELIAADGKAQVTIFATGSEVEIA
VAAHKLLAAKGIAARVVSVPSLDLLLQQDDATRKAIIGDAPVKVAVEAAVRFGWDAVIGPEGGFIGMSSFGASAPAKDLY
KHFGITAEAVAEAAASRLGGK

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=658, Percent_Identity=27.9635258358663, Blast_Score=182, Evalue=9e-46,
Organism=Homo sapiens, GI4507521, Length=658, Percent_Identity=27.9635258358663, Blast_Score=182, Evalue=9e-46,
Organism=Homo sapiens, GI133778974, Length=577, Percent_Identity=26.8630849220104, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI225637459, Length=677, Percent_Identity=23.781388478582, Blast_Score=133, Evalue=6e-31,
Organism=Homo sapiens, GI225637461, Length=649, Percent_Identity=23.5747303543914, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI225637463, Length=646, Percent_Identity=23.6842105263158, Blast_Score=120, Evalue=5e-27,
Organism=Escherichia coli, GI48994911, Length=662, Percent_Identity=50.7552870090634, Blast_Score=640, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=664, Percent_Identity=51.355421686747, Blast_Score=628, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539652, Length=579, Percent_Identity=26.7702936096718, Blast_Score=159, Evalue=5e-39,
Organism=Saccharomyces cerevisiae, GI6325331, Length=663, Percent_Identity=42.0814479638009, Blast_Score=478, Evalue=1e-135,
Organism=Saccharomyces cerevisiae, GI6319593, Length=663, Percent_Identity=41.025641025641, Blast_Score=468, Evalue=1e-132,
Organism=Drosophila melanogaster, GI45551847, Length=576, Percent_Identity=27.9513888888889, Blast_Score=175, Evalue=1e-43,
Organism=Drosophila melanogaster, GI45550715, Length=576, Percent_Identity=27.9513888888889, Blast_Score=175, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24666278, Length=596, Percent_Identity=26.1744966442953, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24645119, Length=541, Percent_Identity=27.9112754158965, Blast_Score=157, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 70521; Mature: 70390

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVDHSRMANAIRALAMDAVEKAKSGHPGLPMGAADVATVLFTEFLKFDAADAHWPDRD
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
RFILSAGHGSMLLYALLYLTGNSELTLDQIKAFRQLDSKTPGHPENCITDSVETTTGPLG
CEEEECCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCC
QGVASSVGTALAERLLAAEFGEIVDHTTYVLCSDGDLMEGVSHEAIALAGHLRLSKLIFL
CHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHCCCCCHHHHHHHEEEEEEEEE
YDDNGISIDGPLTLTDNVDQVARFQAHGWNAMRIDGHDHKAIAEAIKAAKASDRPTMIAC
ECCCCEEECCCEEECCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCCEEEEE
KTTIGFGAPTRAGTSKAHGEPLGAEELAGAKKALGWDYGPFEIPDDVLSAWRAVGAKGAK
EEECCCCCCCCCCCCCCCCCCCCHHHHHCHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCH
AHAEWQSKFDAMDKELRAEFQRRVIDRKRPAALDGAIRKLKDRLVAEPQTIATRKASELA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LEAIVEVVPEMLLGSADLTPSNNTRTKHAKDVTPDDFSGRYIHYGIREMGMAAAMNGIAM
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHCCEEE
HGGFAPAGGTFMCFADYARPSMRIAALSHVPVVYIMTHDSIGLGEDGPTHQPVEHLASLR
CCCCCCCCCCEEEEECCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHH
AMPNMRVFRPADPVETAECWQLALENTKGPTVLALSRQNLTPVRTSKSDDNRCARGAYEL
CCCCCEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHH
IAADGKAQVTIFATGSEVEIAVAAHKLLAAKGIAARVVSVPSLDLLLQQDDATRKAIIGD
EECCCCEEEEEEECCCCEEEHHHHHHHHHHCCHHHHHCCCCCCEEEEECCCCCHHHEECC
APVKVAVEAAVRFGWDAVIGPEGGFIGMSSFGASAPAKDLYKHFGITAEAVAEAAASRLG
CCHHHHHHHHHHCCCCEEECCCCCEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHCC
GK
CC
>Mature Secondary Structure 
AKVDHSRMANAIRALAMDAVEKAKSGHPGLPMGAADVATVLFTEFLKFDAADAHWPDRD
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
RFILSAGHGSMLLYALLYLTGNSELTLDQIKAFRQLDSKTPGHPENCITDSVETTTGPLG
CEEEECCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCC
QGVASSVGTALAERLLAAEFGEIVDHTTYVLCSDGDLMEGVSHEAIALAGHLRLSKLIFL
CHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHCCCCCHHHHHHHEEEEEEEEE
YDDNGISIDGPLTLTDNVDQVARFQAHGWNAMRIDGHDHKAIAEAIKAAKASDRPTMIAC
ECCCCEEECCCEEECCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCCEEEEE
KTTIGFGAPTRAGTSKAHGEPLGAEELAGAKKALGWDYGPFEIPDDVLSAWRAVGAKGAK
EEECCCCCCCCCCCCCCCCCCCCHHHHHCHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCH
AHAEWQSKFDAMDKELRAEFQRRVIDRKRPAALDGAIRKLKDRLVAEPQTIATRKASELA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LEAIVEVVPEMLLGSADLTPSNNTRTKHAKDVTPDDFSGRYIHYGIREMGMAAAMNGIAM
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHCCEEE
HGGFAPAGGTFMCFADYARPSMRIAALSHVPVVYIMTHDSIGLGEDGPTHQPVEHLASLR
CCCCCCCCCCEEEEECCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHH
AMPNMRVFRPADPVETAECWQLALENTKGPTVLALSRQNLTPVRTSKSDDNRCARGAYEL
CCCCCEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHH
IAADGKAQVTIFATGSEVEIAVAAHKLLAAKGIAARVVSVPSLDLLLQQDDATRKAIIGD
EECCCCEEEEEEECCCCEEEHHHHHHHHHHCCHHHHHCCCCCCEEEEECCCCCHHHEECC
APVKVAVEAAVRFGWDAVIGPEGGFIGMSSFGASAPAKDLYKHFGITAEAVAEAAASRLG
CCHHHHHHHHHHCCCCEEECCCCCEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHCC
GK
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7928974 [H]