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The map label for this gene is paaK [H]

Identifier: 86750744

GI number: 86750744

Start: 4170631

End: 4171965

Strand: Reverse

Name: paaK [H]

Synonym: RPB_3634

Alternate gene names: 86750744

Gene position: 4171965-4170631 (Counterclockwise)

Preceding gene: 86750745

Following gene: 86750738

Centisome position: 78.25

GC content: 64.64

Gene sequence:

>1335_bases
ATGGCCGCGAGCATCCATCAATTGCGGGCACCTTCCGGCTACAGCGCCGAGCTCGACGAAGCCGAGCGCGCCTCCCGCGA
CGCGATCGTCTCGCTGCAGACCGAACGCCTGGCCTGGACGCTGACGCATGCCTACGACAACGTCCCCCACTACAGGAATG
CGTTCGACCGAGCCGGTGTGCATCCGCAGGACTTCCGCGACCTCGCCGATCTGGCGAAATTTCCATTCACGTCGAAGACA
GACCTGCGCGACAACTACCCGTTCAGCATGTTCGCGGTGCCACGCGAGCAACTGGTCCGCGTCCACGCGTCGTCGGGTAC
CACCGGCAAGCCGATCGTGGTCGGCTACACGCTGAAGGACATCGACACCTGGGCCACGGTGATGGCGCGTTCGCTGCGCG
CCGCCGGCGCACGCCGCGGCATGATCATTCACAATTCCTACGGCTACGGCCTGTTCACCGGCGGGCTCGGCGCGCACTAC
GGCGGCGAGAAGCTCGGCTGCACCGTGGTGCCGGTCTCCGGCGGCATGACCGAGCGGCAGGTACAACTGATCAACGATTT
CAGGCCCGATGTGATCACCGTGACGCCGAGCTACATGCTGGCGATCCTCGACGAATTCAAACGGCAGGGACTCGACCCGC
GGCAATCGTCGTTGAAATACGGCGTGTTCGGCGCCGAGCCCTGGACCAACGCGATGCGTGCCGAGATCGAGCAGGCGTTC
GACATGGACGCGACCGACATCTACGGGCTGTCCGAAGTGATCGGCCCGGGCGTCGCGCAGGAATGCGTCGAGACCAAGGA
CGGCTTGCACGTCTGGGAGGATCACTTCCTGCCCGAGGTCATCGATCCTGTCACCGGCGCAGTGCTGCCCGATGGCGAGA
AGGGCGAGCTGGTGTTCACCTCGCTGACCAAGGAAGCCTTCCCGGTGATCCGTTATCGCACCCGTGATCTGACCCGGCTG
ATGCCGGGCACGGCTCGGCCCGGGATGCGACGGATGGAAAAGATCACCGGCCGCTCCGACGACATGATCATCCTGCGAGG
TGTCAACGTGTTCCCGACCCAGATCGAGGAAGTGTTGCTCGGGACCGATTGGTGCGGTGGCCATTTCATCATCGAACTGA
CGCGCGAGGGACGGATGGACGAGATGACCGTGCTTGCCGAAGCGCGGACGGAGAGTTGGGACGGCGCCGGCCTGGTACCG
CACGCCGAACGCGTTGCGGCCTACATCAAGAACACCATCGGCATCTCGACGACGATCAAAGTCGTGCCGCCCGACACGCT
GGAGCGTTCGCTCGGCAAGGCCAGGCGGGTGATCGACAAGCGCCCGAAGTCGTGA

Upstream 100 bases:

>100_bases
CCGGAATCGTGATCGCCGAATTCCGTGGCCATTCGCGGTCGATCGGCGGAACGCTGGTGCCGCTGCAACAACCCGATCAA
CGCTGAGAGAGGATAGAGCG

Downstream 100 bases:

>100_bases
GGCGGCCATTGCTGACTGCAGACTGCTGAACGAGGCGGGCGCGAGTGTCCCGGCTGACCGCACGTGGCGACATCACTCCG
CCGCGCGGGTGACGATCTTC

Product: phenylacetate-CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MAASIHQLRAPSGYSAELDEAERASRDAIVSLQTERLAWTLTHAYDNVPHYRNAFDRAGVHPQDFRDLADLAKFPFTSKT
DLRDNYPFSMFAVPREQLVRVHASSGTTGKPIVVGYTLKDIDTWATVMARSLRAAGARRGMIIHNSYGYGLFTGGLGAHY
GGEKLGCTVVPVSGGMTERQVQLINDFRPDVITVTPSYMLAILDEFKRQGLDPRQSSLKYGVFGAEPWTNAMRAEIEQAF
DMDATDIYGLSEVIGPGVAQECVETKDGLHVWEDHFLPEVIDPVTGAVLPDGEKGELVFTSLTKEAFPVIRYRTRDLTRL
MPGTARPGMRRMEKITGRSDDMIILRGVNVFPTQIEEVLLGTDWCGGHFIIELTREGRMDEMTVLAEARTESWDGAGLVP
HAERVAAYIKNTIGISTTIKVVPPDTLERSLGKARRVIDKRPKS

Sequences:

>Translated_444_residues
MAASIHQLRAPSGYSAELDEAERASRDAIVSLQTERLAWTLTHAYDNVPHYRNAFDRAGVHPQDFRDLADLAKFPFTSKT
DLRDNYPFSMFAVPREQLVRVHASSGTTGKPIVVGYTLKDIDTWATVMARSLRAAGARRGMIIHNSYGYGLFTGGLGAHY
GGEKLGCTVVPVSGGMTERQVQLINDFRPDVITVTPSYMLAILDEFKRQGLDPRQSSLKYGVFGAEPWTNAMRAEIEQAF
DMDATDIYGLSEVIGPGVAQECVETKDGLHVWEDHFLPEVIDPVTGAVLPDGEKGELVFTSLTKEAFPVIRYRTRDLTRL
MPGTARPGMRRMEKITGRSDDMIILRGVNVFPTQIEEVLLGTDWCGGHFIIELTREGRMDEMTVLAEARTESWDGAGLVP
HAERVAAYIKNTIGISTTIKVVPPDTLERSLGKARRVIDKRPKS
>Mature_443_residues
AASIHQLRAPSGYSAELDEAERASRDAIVSLQTERLAWTLTHAYDNVPHYRNAFDRAGVHPQDFRDLADLAKFPFTSKTD
LRDNYPFSMFAVPREQLVRVHASSGTTGKPIVVGYTLKDIDTWATVMARSLRAAGARRGMIIHNSYGYGLFTGGLGAHYG
GEKLGCTVVPVSGGMTERQVQLINDFRPDVITVTPSYMLAILDEFKRQGLDPRQSSLKYGVFGAEPWTNAMRAEIEQAFD
MDATDIYGLSEVIGPGVAQECVETKDGLHVWEDHFLPEVIDPVTGAVLPDGEKGELVFTSLTKEAFPVIRYRTRDLTRLM
PGTARPGMRRMEKITGRSDDMIILRGVNVFPTQIEEVLLGTDWCGGHFIIELTREGRMDEMTVLAEARTESWDGAGLVPH
AERVAAYIKNTIGISTTIKVVPPDTLERSLGKARRVIDKRPKS

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=434, Percent_Identity=59.4470046082949, Blast_Score=521, Evalue=1e-149,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 49230; Mature: 49098

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAASIHQLRAPSGYSAELDEAERASRDAIVSLQTERLAWTLTHAYDNVPHYRNAFDRAGV
CCCCCHHHCCCCCCCCCCHHHHHHCCCCEEEEEHHHEEEEEEHHHCCCCHHHHHHHHCCC
HPQDFRDLADLAKFPFTSKTDLRDNYPFSMFAVPREQLVRVHASSGTTGKPIVVGYTLKD
CHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCHHHHEEEECCCCCCCCCEEEEEEHHH
IDTWATVMARSLRAAGARRGMIIHNSYGYGLFTGGLGAHYGGEKLGCTVVPVSGGMTERQ
HHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECCCCCCCCCCCCCEEEEECCCCCCHHH
VQLINDFRPDVITVTPSYMLAILDEFKRQGLDPRQSSLKYGVFGAEPWTNAMRAEIEQAF
HHHHHCCCCCEEEECHHHHHHHHHHHHHCCCCCCHHCCEECCCCCCCHHHHHHHHHHHHH
DMDATDIYGLSEVIGPGVAQECVETKDGLHVWEDHFLPEVIDPVTGAVLPDGEKGELVFT
CCCCHHHCCHHHHHCCCHHHHHHHCCCCCCHHHHHCCHHHHHHHCCCCCCCCCCCCEEEE
SLTKEAFPVIRYRTRDLTRLMPGTARPGMRRMEKITGRSDDMIILRGVNVFPTQIEEVLL
EHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHH
GTDWCGGHFIIELTREGRMDEMTVLAEARTESWDGAGLVPHAERVAAYIKNTIGISTTIK
CCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEE
VVPPDTLERSLGKARRVIDKRPKS
EECCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AASIHQLRAPSGYSAELDEAERASRDAIVSLQTERLAWTLTHAYDNVPHYRNAFDRAGV
CCCCHHHCCCCCCCCCCHHHHHHCCCCEEEEEHHHEEEEEEHHHCCCCHHHHHHHHCCC
HPQDFRDLADLAKFPFTSKTDLRDNYPFSMFAVPREQLVRVHASSGTTGKPIVVGYTLKD
CHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCHHHHEEEECCCCCCCCCEEEEEEHHH
IDTWATVMARSLRAAGARRGMIIHNSYGYGLFTGGLGAHYGGEKLGCTVVPVSGGMTERQ
HHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECCCCCCCCCCCCCEEEEECCCCCCHHH
VQLINDFRPDVITVTPSYMLAILDEFKRQGLDPRQSSLKYGVFGAEPWTNAMRAEIEQAF
HHHHHCCCCCEEEECHHHHHHHHHHHHHCCCCCCHHCCEECCCCCCCHHHHHHHHHHHHH
DMDATDIYGLSEVIGPGVAQECVETKDGLHVWEDHFLPEVIDPVTGAVLPDGEKGELVFT
CCCCHHHCCHHHHHCCCHHHHHHHCCCCCCHHHHHCCHHHHHHHCCCCCCCCCCCCEEEE
SLTKEAFPVIRYRTRDLTRLMPGTARPGMRRMEKITGRSDDMIILRGVNVFPTQIEEVLL
EHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHH
GTDWCGGHFIIELTREGRMDEMTVLAEARTESWDGAGLVPHAERVAAYIKNTIGISTTIK
CCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEE
VVPPDTLERSLGKARRVIDKRPKS
EECCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]