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The map label for this gene is yngJ [H]

Identifier: 86750711

GI number: 86750711

Start: 4133224

End: 4134498

Strand: Reverse

Name: yngJ [H]

Synonym: RPB_3601

Alternate gene names: 86750711

Gene position: 4134498-4133224 (Counterclockwise)

Preceding gene: 86750713

Following gene: 86750708

Centisome position: 77.55

GC content: 62.75

Gene sequence:

>1275_bases
TTGGATTTTTCCCTGCCGCCGGATCTGGTCGCCTATCTCGCCGAGCTCGATCGCTTCATCGACGCCAAGATCAAGCCGCT
GGAACAGGCGGACGACAACATCCGCTTCTTCGATCATCGCCGCGAATGGGCGCGCACCGATTTCGAGGGCGGCGGACTGC
CGCGGCACGACTGGGAAGAGCTGCTGCGCAAGGCGAAGAACATCGCCGATGACGCCGGGCATCTGCGCTTCGCGATTCCG
AAGCGCTATGGCGGGCAGGACGGCACGAATTTGTGGATGGCGGTGATCCGCGAGCACTTCGCCGCCAAGGGCCTCGGCCT
GCACAATGATCTGCAGAACGAGCATTCGATCGTCGGCAATTTCCCGATCGTCAAGATGCTCGACCTCTACGGCCGCGACG
ATCAGAAGGCGATGATCGACGGCTCGATCACCGGAAAATATCGCATCACGTTTGGTCTGACGGAGCCCGATCACGGCTCG
GATGCGACGCATATGGAAACGCGTGCGGTCGAGGCGGTGCGCGACGGCAAGAAGGGCTGGGTGATCAACGGCGAGAAGAT
GTGGACGACCGGCATGCACGTCGCCACGCATTGCGCGCTGTTCGCCCGCACCACCGGCCAAGACGGCGACGCCCGCGGCA
TCACCTGCTTTCTGGTGCCGGCCGATGCGCCCGGCGTCAAGGTCGAGGAATATCTCTGGACCTTCAACATGCCGACCGAT
CATCCGCGGGTGAGCTTCACCGACGTCTTCGTCACCGAAGACGCGTTGTTCGGCGAGGTCGGCCGCGGCCTGTCGCTGGC
GCAATGCTTCGTGCACGAGAACCGCATTCGCCAGGCGGCGAGTTCGCTGGGTGCTGCGGTGTTCTGCATCAATGAAAGCG
TCAAATACGCGCGGGAGCGAAAACCGTTCGGCGAGGAACTGGCGCGCAACCAGGCGATCCAGTTTCCGCTGGTCGAACTC
GCCACCCAGGCCGAAATGCTGCGCCTCTTGATCCGCAAGACCGCGTGGGAGATGGATCAGATGACCCAGGCGCAGGTCGA
GCACACGCTGTCCGACAAGGTGTCGATGTGCAACTACTGGGCGAACCGGCTGTGCGGCCAGGCCGCCGATCGCGCGATCC
AGGTCCACGGCGGCATCGGCTATTCGCGGCACAAGCCGTTCGAACACATCTATCGCCACCACCGCCGCTATCGCATCACC
GAAGGCAGCGAGGAAATCCAGATGCGCAAGGTCGCGGGATTCCTGTTCGGCTATATGGGTGTGAACAAGAGGTGA

Upstream 100 bases:

>100_bases
AATTGGTGCGGCTGAAGCGCGCTTGACTTGTCGTTCGCGGCGCATGTTAATCACTCGCTTAACAAGATCAACAACAACAC
GAACACCGTGGGAGCACGCC

Downstream 100 bases:

>100_bases
TCTCATCAGTGCCCCGGACGCGCTGCGGCATGCCATGCCGCGGCGCAGATCCGGGGTCCCGGTGAGTGGTGCGCAGCCAG
ACCGGGGTCCCGCATCTGCG

Product: Acyl-CoA dehydrogenase-like

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MDFSLPPDLVAYLAELDRFIDAKIKPLEQADDNIRFFDHRREWARTDFEGGGLPRHDWEELLRKAKNIADDAGHLRFAIP
KRYGGQDGTNLWMAVIREHFAAKGLGLHNDLQNEHSIVGNFPIVKMLDLYGRDDQKAMIDGSITGKYRITFGLTEPDHGS
DATHMETRAVEAVRDGKKGWVINGEKMWTTGMHVATHCALFARTTGQDGDARGITCFLVPADAPGVKVEEYLWTFNMPTD
HPRVSFTDVFVTEDALFGEVGRGLSLAQCFVHENRIRQAASSLGAAVFCINESVKYARERKPFGEELARNQAIQFPLVEL
ATQAEMLRLLIRKTAWEMDQMTQAQVEHTLSDKVSMCNYWANRLCGQAADRAIQVHGGIGYSRHKPFEHIYRHHRRYRIT
EGSEEIQMRKVAGFLFGYMGVNKR

Sequences:

>Translated_424_residues
MDFSLPPDLVAYLAELDRFIDAKIKPLEQADDNIRFFDHRREWARTDFEGGGLPRHDWEELLRKAKNIADDAGHLRFAIP
KRYGGQDGTNLWMAVIREHFAAKGLGLHNDLQNEHSIVGNFPIVKMLDLYGRDDQKAMIDGSITGKYRITFGLTEPDHGS
DATHMETRAVEAVRDGKKGWVINGEKMWTTGMHVATHCALFARTTGQDGDARGITCFLVPADAPGVKVEEYLWTFNMPTD
HPRVSFTDVFVTEDALFGEVGRGLSLAQCFVHENRIRQAASSLGAAVFCINESVKYARERKPFGEELARNQAIQFPLVEL
ATQAEMLRLLIRKTAWEMDQMTQAQVEHTLSDKVSMCNYWANRLCGQAADRAIQVHGGIGYSRHKPFEHIYRHHRRYRIT
EGSEEIQMRKVAGFLFGYMGVNKR
>Mature_424_residues
MDFSLPPDLVAYLAELDRFIDAKIKPLEQADDNIRFFDHRREWARTDFEGGGLPRHDWEELLRKAKNIADDAGHLRFAIP
KRYGGQDGTNLWMAVIREHFAAKGLGLHNDLQNEHSIVGNFPIVKMLDLYGRDDQKAMIDGSITGKYRITFGLTEPDHGS
DATHMETRAVEAVRDGKKGWVINGEKMWTTGMHVATHCALFARTTGQDGDARGITCFLVPADAPGVKVEEYLWTFNMPTD
HPRVSFTDVFVTEDALFGEVGRGLSLAQCFVHENRIRQAASSLGAAVFCINESVKYARERKPFGEELARNQAIQFPLVEL
ATQAEMLRLLIRKTAWEMDQMTQAQVEHTLSDKVSMCNYWANRLCGQAADRAIQVHGGIGYSRHKPFEHIYRHHRRYRIT
EGSEEIQMRKVAGFLFGYMGVNKR

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI187960098, Length=362, Percent_Identity=31.2154696132597, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI4557231, Length=362, Percent_Identity=31.2154696132597, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI4557233, Length=348, Percent_Identity=30.7471264367816, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI4501859, Length=348, Percent_Identity=29.0229885057471, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI21361497, Length=411, Percent_Identity=27.7372262773723, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI7656849, Length=290, Percent_Identity=30, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI38505218, Length=302, Percent_Identity=28.1456953642384, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI4501857, Length=385, Percent_Identity=26.2337662337662, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI211971008, Length=296, Percent_Identity=27.027027027027, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI48976061, Length=296, Percent_Identity=27.027027027027, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI76496475, Length=411, Percent_Identity=25.7907542579075, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI4557235, Length=411, Percent_Identity=25.7907542579075, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI226958412, Length=407, Percent_Identity=22.6044226044226, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI226958414, Length=371, Percent_Identity=23.4501347708895, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI7669494, Length=293, Percent_Identity=27.9863481228669, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI4503943, Length=278, Percent_Identity=28.4172661870504, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI1786223, Length=344, Percent_Identity=26.7441860465116, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI87081958, Length=420, Percent_Identity=25.952380952381, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17569725, Length=382, Percent_Identity=30.1047120418848, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17534899, Length=365, Percent_Identity=30.1369863013699, Blast_Score=141, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI17570075, Length=428, Percent_Identity=27.1028037383178, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17508101, Length=347, Percent_Identity=28.5302593659942, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17506239, Length=350, Percent_Identity=26, Blast_Score=118, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17533517, Length=287, Percent_Identity=30.6620209059233, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71985184, Length=340, Percent_Identity=28.5294117647059, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17505929, Length=342, Percent_Identity=29.2397660818713, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17551932, Length=271, Percent_Identity=29.1512915129151, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17538396, Length=408, Percent_Identity=24.0196078431373, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71990804, Length=266, Percent_Identity=27.4436090225564, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17562446, Length=298, Percent_Identity=26.510067114094, Blast_Score=88, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI32563615, Length=242, Percent_Identity=28.099173553719, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71985192, Length=300, Percent_Identity=27, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17534353, Length=267, Percent_Identity=26.2172284644195, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71982178, Length=252, Percent_Identity=26.1904761904762, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24660351, Length=336, Percent_Identity=33.0357142857143, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24666513, Length=422, Percent_Identity=28.1990521327014, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI24646207, Length=277, Percent_Identity=31.0469314079422, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21356377, Length=381, Percent_Identity=28.0839895013123, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI281363737, Length=417, Percent_Identity=26.1390887290168, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI21355753, Length=341, Percent_Identity=25.8064516129032, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI19920834, Length=204, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 48171; Mature: 48171

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFSLPPDLVAYLAELDRFIDAKIKPLEQADDNIRFFDHRREWARTDFEGGGLPRHDWEE
CCCCCCHHHHHHHHHHHHHHHCCCCCHHHCCCCCEEHHHHHHHHCCCCCCCCCCHHHHHH
LLRKAKNIADDAGHLRFAIPKRYGGQDGTNLWMAVIREHFAAKGLGLHNDLQNEHSIVGN
HHHHHHHCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHCCCCCCEECC
FPIVKMLDLYGRDDQKAMIDGSITGKYRITFGLTEPDHGSDATHMETRAVEAVRDGKKGW
CHHHHHHHHHCCCCCCEEECCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCE
VINGEKMWTTGMHVATHCALFARTTGQDGDARGITCFLVPADAPGVKVEEYLWTFNMPTD
EECCCEEEECHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCHHHEEEEECCCCC
HPRVSFTDVFVTEDALFGEVGRGLSLAQCFVHENRIRQAASSLGAAVFCINESVKYARER
CCCEEEEEEEEECHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCEEEEEECHHHHHHHHC
KPFGEELARNQAIQFPLVELATQAEMLRLLIRKTAWEMDQMTQAQVEHTLSDKVSMCNYW
CCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANRLCGQAADRAIQVHGGIGYSRHKPFEHIYRHHRRYRITEGSEEIQMRKVAGFLFGYMG
HHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHCEEECCCHHHHHHHHHHHHHHHHHC
VNKR
CCCC
>Mature Secondary Structure
MDFSLPPDLVAYLAELDRFIDAKIKPLEQADDNIRFFDHRREWARTDFEGGGLPRHDWEE
CCCCCCHHHHHHHHHHHHHHHCCCCCHHHCCCCCEEHHHHHHHHCCCCCCCCCCHHHHHH
LLRKAKNIADDAGHLRFAIPKRYGGQDGTNLWMAVIREHFAAKGLGLHNDLQNEHSIVGN
HHHHHHHCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHCCCCCCEECC
FPIVKMLDLYGRDDQKAMIDGSITGKYRITFGLTEPDHGSDATHMETRAVEAVRDGKKGW
CHHHHHHHHHCCCCCCEEECCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCE
VINGEKMWTTGMHVATHCALFARTTGQDGDARGITCFLVPADAPGVKVEEYLWTFNMPTD
EECCCEEEECHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCHHHEEEEECCCCC
HPRVSFTDVFVTEDALFGEVGRGLSLAQCFVHENRIRQAASSLGAAVFCINESVKYARER
CCCEEEEEEEEECHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCEEEEEECHHHHHHHHC
KPFGEELARNQAIQFPLVELATQAEMLRLLIRKTAWEMDQMTQAQVEHTLSDKVSMCNYW
CCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANRLCGQAADRAIQVHGGIGYSRHKPFEHIYRHHRRYRITEGSEEIQMRKVAGFLFGYMG
HHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHCEEECCCHHHHHHHHHHHHHHHHHC
VNKR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]