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The map label for this gene is aatC [H]

Identifier: 86750084

GI number: 86750084

Start: 3378739

End: 3379959

Strand: Reverse

Name: aatC [H]

Synonym: RPB_2967

Alternate gene names: 86750084

Gene position: 3379959-3378739 (Counterclockwise)

Preceding gene: 86750085

Following gene: 86750083

Centisome position: 63.39

GC content: 66.91

Gene sequence:

>1221_bases
ATGGAAGAATTTTACCGCATCCGCCGCCTGCCGCCTTACGTGTTCGAACAGGTCAACCGGGCCAAGGCGGCCGCGCGGAA
TGCCGGGGCCGACATCATCGACATGGGGATGGGCAACCCGGACCTGCCGGCGCCGCCGCACGTGCTGGAGAAGCTCAAGG
AGACGCTCGGCAAGCCGCGCACCGACCGCTATTCCGCCTCGCGCGGCATCACCGGGCTGCGCAAGGCCCAGGCGGCCTAT
TACGACCGCCGGTTCGGGGTGAAGCTGAATCCCGACACCCAGGTGGTCGCCACGCTCGGCTCCAAGGAAGGCTTCGCCAA
CGTCGCCCAGGCGATCACCGCGCCAGGCGACGTCGTGCTGTGCCCGAATCCGAGCTACCCGATCCACGCCTTCGGCTTCC
TGATGGCCGGCGGCGTGATCCGCTCGGTGCCGTCCGAGCCGACCCCGGAATTCTTCGCCGCGGCCGAGCGCGCCATCATC
CATTCGATCCCGAAGCCGATCGCGCTGATCGCCTGCTATCCGTCGAATCCGACCGCCTATGTGGCCAGCCTCGATTTCTA
CAAGGATCTGGTGGCGTTCGCGAAGAAGCACGAGATCATGATCCTGTCGGATCTGGCCTATGCCGAAGTCTATTTCGACG
ATGCCAACCCGCCGCCGTCGGTGCTGCAGGTGCCGGGCGCGATGGACGTCACCGTCGAGTTCACCTCGATGTCGAAGACG
TTCTCGATGGCCGGCTGGCGGATGGGCTTTGCGGTCGGCAACGAGCGCATCATCGCCGCCCTGGCGCGGGTGAAGTCGTA
TCTCGATTACGGTGCGTTCACGCCGGTGCAGGTCGCCGCCACCGCGGCGCTGAACGGCCCGGACGATTGTATCCGCGAGA
TGCGCGAGACCTACAAGAAGCGCCGCGACGCGCTGGTCGAGAGCTTCGGCCGGGCCGGCTGGGAGATCCCGCCGCCGTCG
GCCTCGATGTTCGCCTGGGCGCCGCTGCCGCCGGCATTTCGCGAGATCGGCAGCATGCAGTTCGCCACCCTGATGGTGGA
GAAATCCGGCGTCGTGGTGTCGCCCGGCGTCGCCTTCGGCGAGCACGGCGAAGGCTATGTTCGCATCGCCATGGTGGAAA
ACGAGCAGCGCATCCGCCAGGCGGCGCGCGGCGTCCGGCGCTTCCTTGAAAGCGGCGTCGAAACGTTGCACAACGTGGTG
CCTCTCGCCACCCGGCGATAG

Upstream 100 bases:

>100_bases
CCGCAAAATCGTGCCAATGGGAGCGTTTCTGCGCCTGAATCGGATTCCCCTCCGATCAAGAACGCGGTAACGATCCAGCC
GCACCCCGGAGTCGAGAACC

Downstream 100 bases:

>100_bases
GCACGGTCGCCGAGGGCCTGCGCGGCCTTCGGCGCAGGTGCTTTGGTTTCTGGCCAGTCCGTTCGGGGCCGTCTCCGGTC
CTTTCCGTCTCAACTCTTCC

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MEEFYRIRRLPPYVFEQVNRAKAAARNAGADIIDMGMGNPDLPAPPHVLEKLKETLGKPRTDRYSASRGITGLRKAQAAY
YDRRFGVKLNPDTQVVATLGSKEGFANVAQAITAPGDVVLCPNPSYPIHAFGFLMAGGVIRSVPSEPTPEFFAAAERAII
HSIPKPIALIACYPSNPTAYVASLDFYKDLVAFAKKHEIMILSDLAYAEVYFDDANPPPSVLQVPGAMDVTVEFTSMSKT
FSMAGWRMGFAVGNERIIAALARVKSYLDYGAFTPVQVAATAALNGPDDCIREMRETYKKRRDALVESFGRAGWEIPPPS
ASMFAWAPLPPAFREIGSMQFATLMVEKSGVVVSPGVAFGEHGEGYVRIAMVENEQRIRQAARGVRRFLESGVETLHNVV
PLATRR

Sequences:

>Translated_406_residues
MEEFYRIRRLPPYVFEQVNRAKAAARNAGADIIDMGMGNPDLPAPPHVLEKLKETLGKPRTDRYSASRGITGLRKAQAAY
YDRRFGVKLNPDTQVVATLGSKEGFANVAQAITAPGDVVLCPNPSYPIHAFGFLMAGGVIRSVPSEPTPEFFAAAERAII
HSIPKPIALIACYPSNPTAYVASLDFYKDLVAFAKKHEIMILSDLAYAEVYFDDANPPPSVLQVPGAMDVTVEFTSMSKT
FSMAGWRMGFAVGNERIIAALARVKSYLDYGAFTPVQVAATAALNGPDDCIREMRETYKKRRDALVESFGRAGWEIPPPS
ASMFAWAPLPPAFREIGSMQFATLMVEKSGVVVSPGVAFGEHGEGYVRIAMVENEQRIRQAARGVRRFLESGVETLHNVV
PLATRR
>Mature_406_residues
MEEFYRIRRLPPYVFEQVNRAKAAARNAGADIIDMGMGNPDLPAPPHVLEKLKETLGKPRTDRYSASRGITGLRKAQAAY
YDRRFGVKLNPDTQVVATLGSKEGFANVAQAITAPGDVVLCPNPSYPIHAFGFLMAGGVIRSVPSEPTPEFFAAAERAII
HSIPKPIALIACYPSNPTAYVASLDFYKDLVAFAKKHEIMILSDLAYAEVYFDDANPPPSVLQVPGAMDVTVEFTSMSKT
FSMAGWRMGFAVGNERIIAALARVKSYLDYGAFTPVQVAATAALNGPDDCIREMRETYKKRRDALVESFGRAGWEIPPPS
ASMFAWAPLPPAFREIGSMQFATLMVEKSGVVVSPGVAFGEHGEGYVRIAMVENEQRIRQAARGVRRFLESGVETLHNVV
PLATRR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=391, Percent_Identity=22.2506393861893, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI169881279, Length=391, Percent_Identity=22.2506393861893, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI56713256, Length=390, Percent_Identity=21.025641025641, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI56713254, Length=390, Percent_Identity=21.2820512820513, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI169881281, Length=243, Percent_Identity=22.2222222222222, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1788722, Length=383, Percent_Identity=49.6083550913838, Blast_Score=407, Evalue=1e-115,
Organism=Escherichia coli, GI1786816, Length=358, Percent_Identity=25.1396648044693, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1788627, Length=267, Percent_Identity=25.8426966292135, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1787710, Length=309, Percent_Identity=23.9482200647249, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71994472, Length=268, Percent_Identity=26.865671641791, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71994476, Length=268, Percent_Identity=26.865671641791, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17567369, Length=424, Percent_Identity=21.4622641509434, Blast_Score=84, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6322401, Length=391, Percent_Identity=22.2506393861893, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI28573069, Length=390, Percent_Identity=24.8717948717949, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24646114, Length=390, Percent_Identity=24.8717948717949, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28573067, Length=390, Percent_Identity=24.8717948717949, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28573065, Length=390, Percent_Identity=24.8717948717949, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 44436; Mature: 44436

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEFYRIRRLPPYVFEQVNRAKAAARNAGADIIDMGMGNPDLPAPPHVLEKLKETLGKPR
CCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHHCCCC
TDRYSASRGITGLRKAQAAYYDRRFGVKLNPDTQVVATLGSKEGFANVAQAITAPGDVVL
CCCHHHHCCCCHHHHHHHHHHHHHCCCEECCCCEEEEECCCCCHHHHHHHHHCCCCCEEE
CPNPSYPIHAFGFLMAGGVIRSVPSEPTPEFFAAAERAIIHSIPKPIALIACYPSNPTAY
CCCCCCCHHHHHHHHHCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEE
VASLDFYKDLVAFAKKHEIMILSDLAYAEVYFDDANPPPSVLQVPGAMDVTVEFTSMSKT
EEEHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCCCCCEECCCCEEEEEEEECHHHH
FSMAGWRMGFAVGNERIIAALARVKSYLDYGAFTPVQVAATAALNGPDDCIREMRETYKK
HHHCCCEEEHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHH
RRDALVESFGRAGWEIPPPSASMFAWAPLPPAFREIGSMQFATLMVEKSGVVVSPGVAFG
HHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHHHHHCCCCEEEEEEECCCEEECCCCCCC
EHGEGYVRIAMVENEQRIRQAARGVRRFLESGVETLHNVVPLATRR
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEEFYRIRRLPPYVFEQVNRAKAAARNAGADIIDMGMGNPDLPAPPHVLEKLKETLGKPR
CCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHHCCCC
TDRYSASRGITGLRKAQAAYYDRRFGVKLNPDTQVVATLGSKEGFANVAQAITAPGDVVL
CCCHHHHCCCCHHHHHHHHHHHHHCCCEECCCCEEEEECCCCCHHHHHHHHHCCCCCEEE
CPNPSYPIHAFGFLMAGGVIRSVPSEPTPEFFAAAERAIIHSIPKPIALIACYPSNPTAY
CCCCCCCHHHHHHHHHCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEE
VASLDFYKDLVAFAKKHEIMILSDLAYAEVYFDDANPPPSVLQVPGAMDVTVEFTSMSKT
EEEHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCCCCCEECCCCEEEEEEEECHHHH
FSMAGWRMGFAVGNERIIAALARVKSYLDYGAFTPVQVAATAALNGPDDCIREMRETYKK
HHHCCCEEEHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHH
RRDALVESFGRAGWEIPPPSASMFAWAPLPPAFREIGSMQFATLMVEKSGVVVSPGVAFG
HHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHHHHHCCCCEEEEEEECCCEEECCCCCCC
EHGEGYVRIAMVENEQRIRQAARGVRRFLESGVETLHNVVPLATRR
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430; 9734305 [H]