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The map label for this gene is mcpA [H]

Identifier: 86750078

GI number: 86750078

Start: 3370786

End: 3372477

Strand: Reverse

Name: mcpA [H]

Synonym: RPB_2961

Alternate gene names: 86750078

Gene position: 3372477-3370786 (Counterclockwise)

Preceding gene: 86750079

Following gene: 86750072

Centisome position: 63.25

GC content: 64.36

Gene sequence:

>1692_bases
ATGTGGAAAGCCCTGCTGAATATCAGAACGTCCTACAAGCTCGCCATCATCTTCACACTTCTCGGTCTCGTCGCGATCGC
GTCCAACGTGGTCATCGCCCGAAACCTGTCGGTTCTCGAACAGAACAACGAGCGGACGACGCACACCTACAAGGTCATCG
ACCGCGCCAAGGCGATCGTCGCCGCGATGGTCGATGGTGAAACCGGCGTGCGTGGATTTCTGGTGAGCGGCGACGACAAA
TTCCTCGAGCCGTATCGAAACTCGGACAAGGCCTTGAAGACGGCGTGGAGCGAGATCAAGACTCTGACTTCGGACAATCC
TGCGCAGCAGAAGCGGCTCGACCAGATCGATGCAGCGGCCTCCGAATGGCGGCAGAAGGTCGCCGAGCGTGAAATTGCTC
TGATGAAGAATCCGCAGACGGTCAATGAAGCGCGCGGCCTCGAAGCTTCGGGCGCCGGCAAGGCGACGATGGATGCGATC
CGCTCGCTGGTCGACGAGATCGTCAAGGCCGAGGCCTCGCTGCTGACGGTGCGTGCCGAAGCTGCGGCGGCTGCGGCGTC
GTCGTCGTTCACGGCGATCATTGCGAGCGGCGTGGCCATGGTCGTGCTGATTGTTCTCGGCCTGCTGTTTCTCGGCCGCG
TCGTCACCCGCGGCATCGTCGACATGACCTCCGCGATGGGAAAACTGGCGCAGAACGATCTGACGGTCGATATTCCGCAC
GCCGACCGGCGCGACGAGATCGGCAAGATGGCGATGGCGGTTCAGGTGTTCAAGGACAACGCCATCCGCGTCCGCCAGCT
CGAGGCCGAGCAGCAGGAAAGCGACCGGATCCGCGCCGAGCAGCGCAAGGCGGAAATGAACAAGCTCGCTTCGGGCTTCG
AAGCGGCCGTCGGCGAGATCGTCGGCACGGTGTCATCGGCCTCCACCGAGCTCGAGGCATCCGCACAAACGCTGACGTCG
TCGGCGGAGCGCGCCCAGCATCTCAGCTCCACCGTCGCTGCAGCTTCCGAAGAAGCCTCCGCCAACGTCCAGTCGGTGGC
TTCGGCGACCGAAGAGCTCAGCTCGTCGATCAGCGAGATCAGCCGGCAGGTTCAGGAGTCGGCGCGAATCGCGGTCGATG
CGGTCAATCAGACGCGCAGCACCAACGAGCGGGTGAGCGAATTGTCCAAGGCCGCGGCGCGGATCGGCGACATCATCGAA
CTGATCAATACGATCGCCGGCCAGACCAATCTGCTGGCGCTCAACGCCACCATCGAGGCGGCCCGTGCCGGCGAGGCGGG
GCGTGGCTTCGCTGTCGTCGCGTCCGAGGTCAAGGCGCTGGCGGAACAGACGGCCAAGGCCACCGGGGAGATCAGCCAGC
AGATCTCCGGCATCCAGTCGGCGACCGGCGAGTCGGTCGACGCGATCAAGCAGGTCAGCATCACCATCGAGCGGCTGTCC
GAGATCGCCTCCACGATCGCCGCGGCGGTCGAGGAGCAGGGCGCCGCGACGCAGGAGATTTCGCGCAACGTGCAGCAGGC
CGCGCACGGCACGCAGCAGGTTTCGTCCAACGTCATCGACGTCCAGCGCGGCGCCACGGAGACCGGTTCGGCCTCATCTC
AGGTGTTGTCGTCGGCACAATTGCTGGCGAAGGACAGCGCCCGGCTGAAGCTGGAAGTGTCGAAATTCGTCGACACGGTG
AGGGCCGCCTGA

Upstream 100 bases:

>100_bases
GTCGTGCGTCTGTGTCCCCAACTCACGCCGGACGTCCCCTCCGGCTGGGCCCGCCTCGTCAAAACCCGCCTTCTTGGCCA
TCGTGAAAGATCGTCCCCCT

Downstream 100 bases:

>100_bases
GCGCTCGGCCGACACCGGCAAGTCATTCAACGAACACGTCGCCGGACGCGAGTCCGGCGACGTCTTCTTGACGAGCCGGG
CCGGCGCGAACCTACGTACA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 563; Mature: 563

Protein sequence:

>563_residues
MWKALLNIRTSYKLAIIFTLLGLVAIASNVVIARNLSVLEQNNERTTHTYKVIDRAKAIVAAMVDGETGVRGFLVSGDDK
FLEPYRNSDKALKTAWSEIKTLTSDNPAQQKRLDQIDAAASEWRQKVAEREIALMKNPQTVNEARGLEASGAGKATMDAI
RSLVDEIVKAEASLLTVRAEAAAAAASSSFTAIIASGVAMVVLIVLGLLFLGRVVTRGIVDMTSAMGKLAQNDLTVDIPH
ADRRDEIGKMAMAVQVFKDNAIRVRQLEAEQQESDRIRAEQRKAEMNKLASGFEAAVGEIVGTVSSASTELEASAQTLTS
SAERAQHLSSTVAAASEEASANVQSVASATEELSSSISEISRQVQESARIAVDAVNQTRSTNERVSELSKAAARIGDIIE
LINTIAGQTNLLALNATIEAARAGEAGRGFAVVASEVKALAEQTAKATGEISQQISGIQSATGESVDAIKQVSITIERLS
EIASTIAAAVEEQGAATQEISRNVQQAAHGTQQVSSNVIDVQRGATETGSASSQVLSSAQLLAKDSARLKLEVSKFVDTV
RAA

Sequences:

>Translated_563_residues
MWKALLNIRTSYKLAIIFTLLGLVAIASNVVIARNLSVLEQNNERTTHTYKVIDRAKAIVAAMVDGETGVRGFLVSGDDK
FLEPYRNSDKALKTAWSEIKTLTSDNPAQQKRLDQIDAAASEWRQKVAEREIALMKNPQTVNEARGLEASGAGKATMDAI
RSLVDEIVKAEASLLTVRAEAAAAAASSSFTAIIASGVAMVVLIVLGLLFLGRVVTRGIVDMTSAMGKLAQNDLTVDIPH
ADRRDEIGKMAMAVQVFKDNAIRVRQLEAEQQESDRIRAEQRKAEMNKLASGFEAAVGEIVGTVSSASTELEASAQTLTS
SAERAQHLSSTVAAASEEASANVQSVASATEELSSSISEISRQVQESARIAVDAVNQTRSTNERVSELSKAAARIGDIIE
LINTIAGQTNLLALNATIEAARAGEAGRGFAVVASEVKALAEQTAKATGEISQQISGIQSATGESVDAIKQVSITIERLS
EIASTIAAAVEEQGAATQEISRNVQQAAHGTQQVSSNVIDVQRGATETGSASSQVLSSAQLLAKDSARLKLEVSKFVDTV
RAA
>Mature_563_residues
MWKALLNIRTSYKLAIIFTLLGLVAIASNVVIARNLSVLEQNNERTTHTYKVIDRAKAIVAAMVDGETGVRGFLVSGDDK
FLEPYRNSDKALKTAWSEIKTLTSDNPAQQKRLDQIDAAASEWRQKVAEREIALMKNPQTVNEARGLEASGAGKATMDAI
RSLVDEIVKAEASLLTVRAEAAAAAASSSFTAIIASGVAMVVLIVLGLLFLGRVVTRGIVDMTSAMGKLAQNDLTVDIPH
ADRRDEIGKMAMAVQVFKDNAIRVRQLEAEQQESDRIRAEQRKAEMNKLASGFEAAVGEIVGTVSSASTELEASAQTLTS
SAERAQHLSSTVAAASEEASANVQSVASATEELSSSISEISRQVQESARIAVDAVNQTRSTNERVSELSKAAARIGDIIE
LINTIAGQTNLLALNATIEAARAGEAGRGFAVVASEVKALAEQTAKATGEISQQISGIQSATGESVDAIKQVSITIERLS
EIASTIAAAVEEQGAATQEISRNVQQAAHGTQQVSSNVIDVQRGATETGSASSQVLSSAQLLAKDSARLKLEVSKFVDTV
RAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=340, Percent_Identity=27.6470588235294, Blast_Score=100, Evalue=5e-22,
Organism=Escherichia coli, GI2367378, Length=252, Percent_Identity=30.952380952381, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1788194, Length=204, Percent_Identity=33.3333333333333, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1788195, Length=211, Percent_Identity=33.6492890995261, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789453, Length=248, Percent_Identity=31.0483870967742, Blast_Score=79, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 59542; Mature: 59542

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWKALLNIRTSYKLAIIFTLLGLVAIASNVVIARNLSVLEQNNERTTHTYKVIDRAKAIV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHH
AAMVDGETGVRGFLVSGDDKFLEPYRNSDKALKTAWSEIKTLTSDNPAQQKRLDQIDAAA
HHHHCCCCCCCEEEECCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
SEWRQKVAEREIALMKNPQTVNEARGLEASGAGKATMDAIRSLVDEIVKAEASLLTVRAE
HHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAAAAASSSFTAIIASGVAMVVLIVLGLLFLGRVVTRGIVDMTSAMGKLAQNDLTVDIPH
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCC
ADRRDEIGKMAMAVQVFKDNAIRVRQLEAEQQESDRIRAEQRKAEMNKLASGFEAAVGEI
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGTVSSASTELEASAQTLTSSAERAQHLSSTVAAASEEASANVQSVASATEELSSSISEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRQVQESARIAVDAVNQTRSTNERVSELSKAAARIGDIIELINTIAGQTNLLALNATIEA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHH
ARAGEAGRGFAVVASEVKALAEQTAKATGEISQQISGIQSATGESVDAIKQVSITIERLS
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
EIASTIAAAVEEQGAATQEISRNVQQAAHGTQQVSSNVIDVQRGATETGSASSQVLSSAQ
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHH
LLAKDSARLKLEVSKFVDTVRAA
HHHCCCCCEEEEHHHHHHHHHCC
>Mature Secondary Structure
MWKALLNIRTSYKLAIIFTLLGLVAIASNVVIARNLSVLEQNNERTTHTYKVIDRAKAIV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHH
AAMVDGETGVRGFLVSGDDKFLEPYRNSDKALKTAWSEIKTLTSDNPAQQKRLDQIDAAA
HHHHCCCCCCCEEEECCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
SEWRQKVAEREIALMKNPQTVNEARGLEASGAGKATMDAIRSLVDEIVKAEASLLTVRAE
HHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAAAAASSSFTAIIASGVAMVVLIVLGLLFLGRVVTRGIVDMTSAMGKLAQNDLTVDIPH
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCC
ADRRDEIGKMAMAVQVFKDNAIRVRQLEAEQQESDRIRAEQRKAEMNKLASGFEAAVGEI
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGTVSSASTELEASAQTLTSSAERAQHLSSTVAAASEEASANVQSVASATEELSSSISEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRQVQESARIAVDAVNQTRSTNERVSELSKAAARIGDIIELINTIAGQTNLLALNATIEA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHH
ARAGEAGRGFAVVASEVKALAEQTAKATGEISQQISGIQSATGESVDAIKQVSITIERLS
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
EIASTIAAAVEEQGAATQEISRNVQQAAHGTQQVSSNVIDVQRGATETGSASSQVLSSAQ
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHH
LLAKDSARLKLEVSKFVDTVRAA
HHHCCCCCEEEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]