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The map label for this gene is guaD [H]

Identifier: 86749931

GI number: 86749931

Start: 3207575

End: 3208105

Strand: Reverse

Name: guaD [H]

Synonym: RPB_2814

Alternate gene names: 86749931

Gene position: 3208105-3207575 (Counterclockwise)

Preceding gene: 86749932

Following gene: 86749928

Centisome position: 60.17

GC content: 65.35

Gene sequence:

>531_bases
ATGTTGCCGGCCGGCGCGACGGTTGCGGAGGCCAAGGCGGCGGCGCCTGCTGCGATCACCGAACAGGATCGCCAGCACAT
GACCCAGGCGATCGCACTGATGCGCAAGGCCGGCGTGGTCGAAAAGACCGGCGGCGCGTTCGGGGCCGTGATCGTGCGCG
ATGGCGAAGTGCTCGCGGCGACAGGCAACAGCGTGCTGCGCGACAACGACCCGTCGGCGCACGCCGAAGTCAATGCGATC
CGCGCCGCGTGCAAGAAGGTCGGCGCGCCGAACCTGCGCGGCGCGACCATGTACACGAGCTGCGAGTGTTGCCCGATGTG
CTACGCGACAGCCTATTGGGCGCGGCTCGACCGGATCTTCTTCGCGGCGTCCTGGACCGACTATGCCGATCTGTTCGACG
ATTCAAACATCGGCGCCGACATGAAGAATCCCTACGCCAAGCGCAAAGTTCGAATCGCTCAGATGATGCGGAGCGATGCG
CAGAAGGTTTGGCAGGAATTCCGCACGCTGCCCGATCGCGCGCGTTACTGA

Upstream 100 bases:

>100_bases
GATCCAAGCTGCGTCGTCGCTCGACACGTTGTTCGCATCAGCGACCGTCGTCCACCGCCGGAATTTCCTCACAACCGGCG
CTGCGGCATTCGGCGCTGCG

Downstream 100 bases:

>100_bases
AGCTGCGCTCGGGGGGCGTCCGGGCGAGGGCCACAAAGCAAAACGGCGAACCGCCTGGGCGGTTCGCCGTTCCTTCTGAA
GACCTTCAGGCGATCAGCCG

Product: twin-arginine translocation pathway signal

Products: NA

Alternate protein names: GDEase; Guanase; Guanine aminase; Guanine aminohydrolase; GAH [H]

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MLPAGATVAEAKAAAPAAITEQDRQHMTQAIALMRKAGVVEKTGGAFGAVIVRDGEVLAATGNSVLRDNDPSAHAEVNAI
RAACKKVGAPNLRGATMYTSCECCPMCYATAYWARLDRIFFAASWTDYADLFDDSNIGADMKNPYAKRKVRIAQMMRSDA
QKVWQEFRTLPDRARY

Sequences:

>Translated_176_residues
MLPAGATVAEAKAAAPAAITEQDRQHMTQAIALMRKAGVVEKTGGAFGAVIVRDGEVLAATGNSVLRDNDPSAHAEVNAI
RAACKKVGAPNLRGATMYTSCECCPMCYATAYWARLDRIFFAASWTDYADLFDDSNIGADMKNPYAKRKVRIAQMMRSDA
QKVWQEFRTLPDRARY
>Mature_176_residues
MLPAGATVAEAKAAAPAAITEQDRQHMTQAIALMRKAGVVEKTGGAFGAVIVRDGEVLAATGNSVLRDNDPSAHAEVNAI
RAACKKVGAPNLRGATMYTSCECCPMCYATAYWARLDRIFFAASWTDYADLFDDSNIGADMKNPYAKRKVRIAQMMRSDA
QKVWQEFRTLPDRARY

Specific function: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17554608, Length=142, Percent_Identity=38.7323943661972, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17555996, Length=168, Percent_Identity=33.9285714285714, Blast_Score=101, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.3 [H]

Molecular weight: Translated: 19198; Mature: 19198

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPAGATVAEAKAAAPAAITEQDRQHMTQAIALMRKAGVVEKTGGAFGAVIVRDGEVLAA
CCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCEEEEE
TGNSVLRDNDPSAHAEVNAIRAACKKVGAPNLRGATMYTSCECCPMCYATAYWARLDRIF
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHH
FAASWTDYADLFDDSNIGADMKNPYAKRKVRIAQMMRSDAQKVWQEFRTLPDRARY
HHCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLPAGATVAEAKAAAPAAITEQDRQHMTQAIALMRKAGVVEKTGGAFGAVIVRDGEVLAA
CCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCEEEEE
TGNSVLRDNDPSAHAEVNAIRAACKKVGAPNLRGATMYTSCECCPMCYATAYWARLDRIF
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHH
FAASWTDYADLFDDSNIGADMKNPYAKRKVRIAQMMRSDAQKVWQEFRTLPDRARY
HHCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 11101664 [H]