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The map label for this gene is thiL [H]

Identifier: 86749757

GI number: 86749757

Start: 3019636

End: 3020607

Strand: Direct

Name: thiL [H]

Synonym: RPB_2640

Alternate gene names: 86749757

Gene position: 3019636-3020607 (Clockwise)

Preceding gene: 86749756

Following gene: 86749758

Centisome position: 56.64

GC content: 69.55

Gene sequence:

>972_bases
ATGCCCTCCGGTGAAGACGATCTGATTGCCCGCTACTTCAAGCCGCTTGCGACCGATCCGGGCGCGCTGGGGCTGGTCGA
CGACGCGGCGGTGCTGGCGGCGTCGCGCGACGATCTGGTGCTGACCACCGACGCCATCGTCGAGGGCGTGCATTACCTGC
CCGGCGATCCGCCCCGGGCCATCGCCCGCAAGGCGCTGCGGGTGAACCTGTCCGACCTCGCCGCCAAGGGGGCGACGCCC
GCGGGGTTCCTGCTGACGCTGGCGCTGCGCAGCGCCGACGAGCGCTTCCTGGCGCCGTTCGCACAGGCGCTCGGCGAGGA
TGCCGCCCTTTTCGATTGTCCGCTGCTCGGCGGCGATACGGTGTCCACCCCGGGGCCGATGATGATTTCGATCACCGCCA
TCGGCCGGGTGCCGCCGGGTCGCATGGTGCGGCGCAACACGCTTTGTGCCGGGGACCGGATCCTCGTCACCGGCACGATC
GGCGACTCGGCACTCGGCCTCGACCTGCTGCAGGGCGCGAATGCCGACATCTCCGACGAGCATCGCGCCTTTCTGATCGA
CCGCTATCGCGTGCCGCAGCCGCGTTTGGCCTTGGCGCAAGCCATACGTGACCATGCCGGCGCGGCGATGGACGTGTCCG
ACGGGCTGGCAGGCGATCTCGCCAAGATGTGCGCCGCCTCCGGCGTCACCGCGATCCTCGACGCTGCGGCCGTCCCGCTC
TCCGCTGCGGCGCAGGCGATGATCTCGGGCGAGCCGGCGAAGCTGGCCCGCGTGCTCGGGGGCGGTGACGACTATGAGCT
GCTTTGCGGCGTTGCAGCACAGCAGCTCGACCCGTTTCTTGCTGCAGCGCAGCGAATAGGGGTTTCGGTCAGCGTCATCG
GCTCCGCCGAAGCCGGAACCGGAGCGCCGCGATGGCGCGACGCCGAGCATCGTGACATCGCGCTGTCAGGGCTGTCATAC
AGTCATTTCTAG

Upstream 100 bases:

>100_bases
CGTCGCCCCTCACCCCAACCCTCTCCCCGCAAGAGCGGGGCGAGGGAGCGCGCCGTGCCGCGAGGCGACCATCGCGGCAC
AACGTCGAGGTTATTAGTGC

Downstream 100 bases:

>100_bases
CGATTAGTCGCAGGTATTCCGGCGCAAGGGATGCGTCTGGAATTCGCCCAAGGCCGCGGGAAAAGCCGCGCTTAGTCCCT
TCGCAGCGATTGCGGAGCAC

Product: thiamine-monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MPSGEDDLIARYFKPLATDPGALGLVDDAAVLAASRDDLVLTTDAIVEGVHYLPGDPPRAIARKALRVNLSDLAAKGATP
AGFLLTLALRSADERFLAPFAQALGEDAALFDCPLLGGDTVSTPGPMMISITAIGRVPPGRMVRRNTLCAGDRILVTGTI
GDSALGLDLLQGANADISDEHRAFLIDRYRVPQPRLALAQAIRDHAGAAMDVSDGLAGDLAKMCAASGVTAILDAAAVPL
SAAAQAMISGEPAKLARVLGGGDDYELLCGVAAQQLDPFLAAAQRIGVSVSVIGSAEAGTGAPRWRDAEHRDIALSGLSY
SHF

Sequences:

>Translated_323_residues
MPSGEDDLIARYFKPLATDPGALGLVDDAAVLAASRDDLVLTTDAIVEGVHYLPGDPPRAIARKALRVNLSDLAAKGATP
AGFLLTLALRSADERFLAPFAQALGEDAALFDCPLLGGDTVSTPGPMMISITAIGRVPPGRMVRRNTLCAGDRILVTGTI
GDSALGLDLLQGANADISDEHRAFLIDRYRVPQPRLALAQAIRDHAGAAMDVSDGLAGDLAKMCAASGVTAILDAAAVPL
SAAAQAMISGEPAKLARVLGGGDDYELLCGVAAQQLDPFLAAAQRIGVSVSVIGSAEAGTGAPRWRDAEHRDIALSGLSY
SHF
>Mature_322_residues
PSGEDDLIARYFKPLATDPGALGLVDDAAVLAASRDDLVLTTDAIVEGVHYLPGDPPRAIARKALRVNLSDLAAKGATPA
GFLLTLALRSADERFLAPFAQALGEDAALFDCPLLGGDTVSTPGPMMISITAIGRVPPGRMVRRNTLCAGDRILVTGTIG
DSALGLDLLQGANADISDEHRAFLIDRYRVPQPRLALAQAIRDHAGAAMDVSDGLAGDLAKMCAASGVTAILDAAAVPLS
AAAQAMISGEPAKLARVLGGGDDYELLCGVAAQQLDPFLAAAQRIGVSVSVIGSAEAGTGAPRWRDAEHRDIALSGLSYS
HF

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=328, Percent_Identity=40.2439024390244, Blast_Score=174, Evalue=8e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 33282; Mature: 33151

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSGEDDLIARYFKPLATDPGALGLVDDAAVLAASRDDLVLTTDAIVEGVHYLPGDPPRA
CCCCHHHHHHHHHHHHCCCCCCEEECCCHHHEEECCCCEEEEHHHHHCCHHCCCCCCHHH
IARKALRVNLSDLAAKGATPAGFLLTLALRSADERFLAPFAQALGEDAALFDCPLLGGDT
HHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEECCCCCCCC
VSTPGPMMISITAIGRVPPGRMVRRNTLCAGDRILVTGTIGDSALGLDLLQGANADISDE
CCCCCCEEEEEEEECCCCCCHHHHCCCCCCCCEEEEEECCCCCHHHHHHHCCCCCCCCCC
HRAFLIDRYRVPQPRLALAQAIRDHAGAAMDVSDGLAGDLAKMCAASGVTAILDAAAVPL
CCEEEEECCCCCCHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHCCHHHHHHHHHCCH
SAAAQAMISGEPAKLARVLGGGDDYELLCGVAAQQLDPFLAAAQRIGVSVSVIGSAEAGT
HHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCC
GAPRWRDAEHRDIALSGLSYSHF
CCCCCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
PSGEDDLIARYFKPLATDPGALGLVDDAAVLAASRDDLVLTTDAIVEGVHYLPGDPPRA
CCCHHHHHHHHHHHHCCCCCCEEECCCHHHEEECCCCEEEEHHHHHCCHHCCCCCCHHH
IARKALRVNLSDLAAKGATPAGFLLTLALRSADERFLAPFAQALGEDAALFDCPLLGGDT
HHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEECCCCCCCC
VSTPGPMMISITAIGRVPPGRMVRRNTLCAGDRILVTGTIGDSALGLDLLQGANADISDE
CCCCCCEEEEEEEECCCCCCHHHHCCCCCCCCEEEEEECCCCCHHHHHHHCCCCCCCCCC
HRAFLIDRYRVPQPRLALAQAIRDHAGAAMDVSDGLAGDLAKMCAASGVTAILDAAAVPL
CCEEEEECCCCCCHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHCCHHHHHHHHHCCH
SAAAQAMISGEPAKLARVLGGGDDYELLCGVAAQQLDPFLAAAQRIGVSVSVIGSAEAGT
HHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCC
GAPRWRDAEHRDIALSGLSYSHF
CCCCCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]