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The map label for this gene is iorA [H]

Identifier: 86749400

GI number: 86749400

Start: 2628922

End: 2629386

Strand: Direct

Name: iorA [H]

Synonym: RPB_2280

Alternate gene names: 86749400

Gene position: 2628922-2629386 (Clockwise)

Preceding gene: 86749399

Following gene: 86749401

Centisome position: 49.31

GC content: 66.02

Gene sequence:

>465_bases
ATGGCCGCGTACGCACTCAAGATCAACGGACGCACTCACACCGTCGATGTCGATCCCGACACCCCGCTGCTGTGGGCAAT
CCGCGACGGCGCCGGACTGATGGGAACTAAGTACGGCTGCGGCGTCGCGCAATGCGGCGCCTGCACGGTTTTCGTCGACG
GCAATACGGTGCGCTCGTGTTCGCTGCCGGTGTCGGCGGTGGGAACCAGCGAAGTCACGACGATCGAAGGCCTTCGCGGC
AGGGAAGGCGCTGCGGTGCAGCAGGCCTGGGTGGCGCTGGACGTGCCGCAATGCGGCTATTGCCAGTCCGGCCAGGTGAT
GAGCGCGACCTCCTTGCTGTCGAAAAATCCGAAGCCGACCGATCGGGACATCGATCTGGCGATGACCGGCAACATCTGCC
GCTGCGCCACCTACGTGCGGATCCGCGCCGCGATCCACCAGGCCGCCAAGTCGCTGGAGGGCTGA

Upstream 100 bases:

>100_bases
GTGTAAACACATACGTTGGATTGCCCGGACGCAAAATCTTGTGATTGTCGTTGCGAGCTATTCTTATGTATGATCTCCGT
CATATCAAACGGGGGTCGAC

Downstream 100 bases:

>100_bases
GCATGACCATTCATGACACGAAGCTGTCGCGCCGTTCGCTGCTGAAGGCCGGCGCCGGCCTCGTCATCGGCGCCTATGTC
GTTCGCGGCGGCAAGGCGTT

Product: (2Fe-2S)-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MAAYALKINGRTHTVDVDPDTPLLWAIRDGAGLMGTKYGCGVAQCGACTVFVDGNTVRSCSLPVSAVGTSEVTTIEGLRG
REGAAVQQAWVALDVPQCGYCQSGQVMSATSLLSKNPKPTDRDIDLAMTGNICRCATYVRIRAAIHQAAKSLEG

Sequences:

>Translated_154_residues
MAAYALKINGRTHTVDVDPDTPLLWAIRDGAGLMGTKYGCGVAQCGACTVFVDGNTVRSCSLPVSAVGTSEVTTIEGLRG
REGAAVQQAWVALDVPQCGYCQSGQVMSATSLLSKNPKPTDRDIDLAMTGNICRCATYVRIRAAIHQAAKSLEG
>Mature_153_residues
AAYALKINGRTHTVDVDPDTPLLWAIRDGAGLMGTKYGCGVAQCGACTVFVDGNTVRSCSLPVSAVGTSEVTTIEGLRGR
EGAAVQQAWVALDVPQCGYCQSGQVMSATSLLSKNPKPTDRDIDLAMTGNICRCATYVRIRAAIHQAAKSLEG

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=144, Percent_Identity=36.8055555555556, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1786480, Length=165, Percent_Identity=40.6060606060606, Blast_Score=110, Evalue=4e-26,
Organism=Escherichia coli, GI1789232, Length=137, Percent_Identity=39.4160583941606, Blast_Score=91, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17540638, Length=159, Percent_Identity=37.7358490566038, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17539860, Length=153, Percent_Identity=33.9869281045752, Blast_Score=90, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI32566215, Length=153, Percent_Identity=33.9869281045752, Blast_Score=90, Evalue=4e-19,
Organism=Drosophila melanogaster, GI17737937, Length=144, Percent_Identity=37.5, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24647193, Length=160, Percent_Identity=35.625, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24647201, Length=152, Percent_Identity=33.5526315789474, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24647199, Length=154, Percent_Identity=34.4155844155844, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 16136; Mature: 16004

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
5.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAYALKINGRTHTVDVDPDTPLLWAIRDGAGLMGTKYGCGVAQCGACTVFVDGNTVRSC
CCEEEEEECCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCEEEEC
SLPVSAVGTSEVTTIEGLRGREGAAVQQAWVALDVPQCGYCQSGQVMSATSLLSKNPKPT
CCCEEECCCCCEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCCCEEHHHHHHHCCCCCC
DRDIDLAMTGNICRCATYVRIRAAIHQAAKSLEG
CCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AAYALKINGRTHTVDVDPDTPLLWAIRDGAGLMGTKYGCGVAQCGACTVFVDGNTVRSC
CEEEEEECCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCEEEEC
SLPVSAVGTSEVTTIEGLRGREGAAVQQAWVALDVPQCGYCQSGQVMSATSLLSKNPKPT
CCCEEECCCCCEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCCCEEHHHHHHHCCCCCC
DRDIDLAMTGNICRCATYVRIRAAIHQAAKSLEG
CCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]