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The map label for this gene is iorB [H]

Identifier: 86749401

GI number: 86749401

Start: 2629389

End: 2631557

Strand: Direct

Name: iorB [H]

Synonym: RPB_2281

Alternate gene names: 86749401

Gene position: 2629389-2631557 (Clockwise)

Preceding gene: 86749400

Following gene: 86749402

Centisome position: 49.32

GC content: 67.08

Gene sequence:

>2169_bases
ATGACCATTCATGACACGAAGCTGTCGCGCCGTTCGCTGCTGAAGGCCGGCGCCGGCCTCGTCATCGGCGCCTATGTCGT
TCGCGGCGGCAAGGCGTTTGCGCAGTCGCCCGCCCCGAGCGCCCCGAACATCGCGCCCAACACCTTTCTGATCATCGGCG
CCGACGACACGGTCACCGTGCTGTGCAAGGGCATCGAGTTCGGGCAGGGCCCGTTCACCGGCATGGCGACGCTGGTCGCC
GAGGAACTCGACGCCGACTGGTCGCAGATGCGGGCCGATCATGCGCCGTCGAACCCGGCGCTCTACAAGAACCTGGCGTT
CGGTGTGCAGGGCACCGGCGGCTCGACGCAGATGGCGAATTCCTACATCCAGATGCGTCAGGTCGGCGCCGCCGCCCGCG
AGATGCTGGTGGGCGCCGCCGCCGAGTCCTGGAAGGTGCCGGCCTCCGAGATCACCGTCGACAAGGGCGTGATCCGTCAT
GCCTCCGGCAAGCAGGGCCGGTTCGGCGAATTCGCCGAGCAGGCGATGCTGCGCCCGGTGCCGAGCGCGCCGAAGCTGAA
GGATCCGTCGCAGTTCAGGCTGATCGGCAAGGAAGGCGTGGTGAAGCGGCTCGACAGCGCCGCCAAATCCGACGGCAGCG
CGCTGTTCACCATGGATATCCACGGGCCCGACATGCTGACCGTGCTGATCGCGCGGTCGCCGAAATTCGGCGGCGCGGTG
AGGTCGTTCGATGCGACCAAGGCCAAGGCGGTCGCCGGTGTGGTCGATATCAAGCAGGTGCCGACCGGCGTGGCTGTCTA
TGCCAAGGGGTTCTGGCCGGCCAAGACTGCGCGCGAGCTGCTGCAGATCGAGTGGGACAACAGCAAGGCCGAGACCCGCG
GCACCACGGAAATCCTGACCGAGTTCCGCGCGCTGGCGAAGACGCCGGGCAAGGTGGTGACGCAGCACGGTGACGTCGAC
GGCAGCTTCGCCAAAGGCGGGCAGGTGATCGAGGCGGAGTACGTGTTTCCGTATCTCGCCCACGCCGCGATGGAGCCGCT
GAACGGTTATCTCAAATGGGACGGCGACACTGCCACCGCCAAATATGGCTGCCAGTTCCCGACGCCCGATCACGCCGCGA
TCGCCCAGGTGCTCGGCCTCGGCATGGACAAGGTGAAGATCGACACGATCCTCGCCGGCGGCAGCTTCGGCCGCCGCGCG
CAGCAGACGACGCATCAGGCCATCGAACTCGCCGAGGTCGCCAAGGCGATCGGACCCGGCAAGGCATTGAAGCTGGTGTG
GACCCGCGAGGACGACATGCGGGGCGGCTATTATCGGCCGTTCGGCGTGCACCGGATGCGCGGCGTGGTGCGCGACGGCA
GGATCGAGGGCTGGACCGACACCATCGTGGGCCAGTCCATCATGAAAGGCTCGCCGTTCGAAGCGATGACCTTCAAGGAC
GGCATGGACGCCACCGCTTATGAGGGCTCCAACGAGCCGCCCTACGAGATCGCCAATTTCCGCTGCGACCTTCACCAGGT
CGATCTCGGCGTGCCGGTGCTGTGGTGGCGGTCGGTCGGCCACACCCATACCGGCTATGCGGTCGAAGCCTTTGTCGACG
AGTTGCTGACGGCGACCGGGCAGGATCCGGTCGAGGGCCGGCTGGCCTTGATGGGCAATCGCAAGCCGCGCCACGCCGGC
GTGCTCAAAGCGGTCGCCGAATTGTCGAACTGGAAGGGCGCCAAGCCGGAGGCCGGCCGCGCTCGCGGCGTCGCGGTGGT
GGAGAGCTTCAACACCTTCGTGGCGCAAGTGGTCGAACTGTCGATGAGCGCCGATGGGCCGGTGGTGCACAAAGTGTGGT
GCGCGGTGGATTGCGGCGTCCCGGTCAACCCGGACATCATCCGCGCCCAGATGGAGGGCGGCATCGGCTTCGCGCTCGGC
CACATCCTCTATGCGCAGCAGCCGATTGAAGCCGGCGCGCCGGTGTCCGGCAATTTCGACACCTATCGCTCGCTGCGGAT
CAACGAGATGCCGCAGATCGAGGTGACGATCATTCCCTCGACCGAAAAGCCGACCGGTGTCGGCGAGCCGGGCGTGCCGC
CGCTCGGCCCGGCCGTCGCCAACGCCATGGCGAAACTGGGTCTGCCCCGTCCGCGGAAATTGCCGATCGTGCCGGGAGCC
AACGCATGA

Upstream 100 bases:

>100_bases
ACATCGATCTGGCGATGACCGGCAACATCTGCCGCTGCGCCACCTACGTGCGGATCCGCGCCGCGATCCACCAGGCCGCC
AAGTCGCTGGAGGGCTGAGC

Downstream 100 bases:

>100_bases
GCCGGCTCCGTCATCTTGTACTGGCCGGTGCCGCCGGCATCCTGGCGGCGTGTGTGCTGACGATCGCCGGCCCCGTGCTG
CAGGGCGAGGCCGACGCCGC

Product: twin-arginine translocation pathway signal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 722; Mature: 721

Protein sequence:

>722_residues
MTIHDTKLSRRSLLKAGAGLVIGAYVVRGGKAFAQSPAPSAPNIAPNTFLIIGADDTVTVLCKGIEFGQGPFTGMATLVA
EELDADWSQMRADHAPSNPALYKNLAFGVQGTGGSTQMANSYIQMRQVGAAAREMLVGAAAESWKVPASEITVDKGVIRH
ASGKQGRFGEFAEQAMLRPVPSAPKLKDPSQFRLIGKEGVVKRLDSAAKSDGSALFTMDIHGPDMLTVLIARSPKFGGAV
RSFDATKAKAVAGVVDIKQVPTGVAVYAKGFWPAKTARELLQIEWDNSKAETRGTTEILTEFRALAKTPGKVVTQHGDVD
GSFAKGGQVIEAEYVFPYLAHAAMEPLNGYLKWDGDTATAKYGCQFPTPDHAAIAQVLGLGMDKVKIDTILAGGSFGRRA
QQTTHQAIELAEVAKAIGPGKALKLVWTREDDMRGGYYRPFGVHRMRGVVRDGRIEGWTDTIVGQSIMKGSPFEAMTFKD
GMDATAYEGSNEPPYEIANFRCDLHQVDLGVPVLWWRSVGHTHTGYAVEAFVDELLTATGQDPVEGRLALMGNRKPRHAG
VLKAVAELSNWKGAKPEAGRARGVAVVESFNTFVAQVVELSMSADGPVVHKVWCAVDCGVPVNPDIIRAQMEGGIGFALG
HILYAQQPIEAGAPVSGNFDTYRSLRINEMPQIEVTIIPSTEKPTGVGEPGVPPLGPAVANAMAKLGLPRPRKLPIVPGA
NA

Sequences:

>Translated_722_residues
MTIHDTKLSRRSLLKAGAGLVIGAYVVRGGKAFAQSPAPSAPNIAPNTFLIIGADDTVTVLCKGIEFGQGPFTGMATLVA
EELDADWSQMRADHAPSNPALYKNLAFGVQGTGGSTQMANSYIQMRQVGAAAREMLVGAAAESWKVPASEITVDKGVIRH
ASGKQGRFGEFAEQAMLRPVPSAPKLKDPSQFRLIGKEGVVKRLDSAAKSDGSALFTMDIHGPDMLTVLIARSPKFGGAV
RSFDATKAKAVAGVVDIKQVPTGVAVYAKGFWPAKTARELLQIEWDNSKAETRGTTEILTEFRALAKTPGKVVTQHGDVD
GSFAKGGQVIEAEYVFPYLAHAAMEPLNGYLKWDGDTATAKYGCQFPTPDHAAIAQVLGLGMDKVKIDTILAGGSFGRRA
QQTTHQAIELAEVAKAIGPGKALKLVWTREDDMRGGYYRPFGVHRMRGVVRDGRIEGWTDTIVGQSIMKGSPFEAMTFKD
GMDATAYEGSNEPPYEIANFRCDLHQVDLGVPVLWWRSVGHTHTGYAVEAFVDELLTATGQDPVEGRLALMGNRKPRHAG
VLKAVAELSNWKGAKPEAGRARGVAVVESFNTFVAQVVELSMSADGPVVHKVWCAVDCGVPVNPDIIRAQMEGGIGFALG
HILYAQQPIEAGAPVSGNFDTYRSLRINEMPQIEVTIIPSTEKPTGVGEPGVPPLGPAVANAMAKLGLPRPRKLPIVPGA
NA
>Mature_721_residues
TIHDTKLSRRSLLKAGAGLVIGAYVVRGGKAFAQSPAPSAPNIAPNTFLIIGADDTVTVLCKGIEFGQGPFTGMATLVAE
ELDADWSQMRADHAPSNPALYKNLAFGVQGTGGSTQMANSYIQMRQVGAAAREMLVGAAAESWKVPASEITVDKGVIRHA
SGKQGRFGEFAEQAMLRPVPSAPKLKDPSQFRLIGKEGVVKRLDSAAKSDGSALFTMDIHGPDMLTVLIARSPKFGGAVR
SFDATKAKAVAGVVDIKQVPTGVAVYAKGFWPAKTARELLQIEWDNSKAETRGTTEILTEFRALAKTPGKVVTQHGDVDG
SFAKGGQVIEAEYVFPYLAHAAMEPLNGYLKWDGDTATAKYGCQFPTPDHAAIAQVLGLGMDKVKIDTILAGGSFGRRAQ
QTTHQAIELAEVAKAIGPGKALKLVWTREDDMRGGYYRPFGVHRMRGVVRDGRIEGWTDTIVGQSIMKGSPFEAMTFKDG
MDATAYEGSNEPPYEIANFRCDLHQVDLGVPVLWWRSVGHTHTGYAVEAFVDELLTATGQDPVEGRLALMGNRKPRHAGV
LKAVAELSNWKGAKPEAGRARGVAVVESFNTFVAQVVELSMSADGPVVHKVWCAVDCGVPVNPDIIRAQMEGGIGFALGH
ILYAQQPIEAGAPVSGNFDTYRSLRINEMPQIEVTIIPSTEKPTGVGEPGVPPLGPAVANAMAKLGLPRPRKLPIVPGAN
A

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012368
- InterPro:   IPR006311 [H]

Pfam domain/function: PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 76965; Mature: 76834

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIHDTKLSRRSLLKAGAGLVIGAYVVRGGKAFAQSPAPSAPNIAPNTFLIIGADDTVTV
CCCCCCHHHHHHHHHCCCCCEEEHHHHCCCHHHCCCCCCCCCCCCCCEEEEEECCCCEEE
LCKGIEFGQGPFTGMATLVAEELDADWSQMRADHAPSNPALYKNLAFGVQGTGGSTQMAN
EEECCCCCCCCCHHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHEEEEECCCCCCHHHHH
SYIQMRQVGAAAREMLVGAAAESWKVPASEITVDKGVIRHASGKQGRFGEFAEQAMLRPV
HHHHHHHHHHHHHHHHHHHCHHCCCCCHHHEEECHHHHCCCCCCCCCCHHHHHHHHHCCC
PSAPKLKDPSQFRLIGKEGVVKRLDSAAKSDGSALFTMDIHGPDMLTVLIARSPKFGGAV
CCCCCCCCCCCEEEECHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEECCCCCCCCH
RSFDATKAKAVAGVVDIKQVPTGVAVYAKGFWPAKTARELLQIEWDNSKAETRGTTEILT
HCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHEEEEECCCCCCCCCHHHHHH
EFRALAKTPGKVVTQHGDVDGSFAKGGQVIEAEYVFPYLAHAAMEPLNGYLKWDGDTATA
HHHHHHCCCCCEEEECCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCEEEECCCCCCE
KYGCQFPTPDHAAIAQVLGLGMDKVKIDTILAGGSFGRRAQQTTHQAIELAEVAKAIGPG
EECCCCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCC
KALKLVWTREDDMRGGYYRPFGVHRMRGVVRDGRIEGWTDTIVGQSIMKGSPFEAMTFKD
CEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEECC
GMDATAYEGSNEPPYEIANFRCDLHQVDLGVPVLWWRSVGHTHTGYAVEAFVDELLTATG
CCCCCCCCCCCCCCHHHHHEEECEEEECCCCCEEEHHCCCCCCCCHHHHHHHHHHHHHCC
QDPVEGRLALMGNRKPRHAGVLKAVAELSNWKGAKPEAGRARGVAVVESFNTFVAQVVEL
CCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
SMSADGPVVHKVWCAVDCGVPVNPDIIRAQMEGGIGFALGHILYAQQPIEAGAPVSGNFD
HCCCCCCEEEEEEEEEECCCCCCHHHEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCH
TYRSLRINEMPQIEVTIIPSTEKPTGVGEPGVPPLGPAVANAMAKLGLPRPRKLPIVPGA
HHHEEEECCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCC
NA
CC
>Mature Secondary Structure 
TIHDTKLSRRSLLKAGAGLVIGAYVVRGGKAFAQSPAPSAPNIAPNTFLIIGADDTVTV
CCCCCHHHHHHHHHCCCCCEEEHHHHCCCHHHCCCCCCCCCCCCCCEEEEEECCCCEEE
LCKGIEFGQGPFTGMATLVAEELDADWSQMRADHAPSNPALYKNLAFGVQGTGGSTQMAN
EEECCCCCCCCCHHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHEEEEECCCCCCHHHHH
SYIQMRQVGAAAREMLVGAAAESWKVPASEITVDKGVIRHASGKQGRFGEFAEQAMLRPV
HHHHHHHHHHHHHHHHHHHCHHCCCCCHHHEEECHHHHCCCCCCCCCCHHHHHHHHHCCC
PSAPKLKDPSQFRLIGKEGVVKRLDSAAKSDGSALFTMDIHGPDMLTVLIARSPKFGGAV
CCCCCCCCCCCEEEECHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEECCCCCCCCH
RSFDATKAKAVAGVVDIKQVPTGVAVYAKGFWPAKTARELLQIEWDNSKAETRGTTEILT
HCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHEEEEECCCCCCCCCHHHHHH
EFRALAKTPGKVVTQHGDVDGSFAKGGQVIEAEYVFPYLAHAAMEPLNGYLKWDGDTATA
HHHHHHCCCCCEEEECCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCEEEECCCCCCE
KYGCQFPTPDHAAIAQVLGLGMDKVKIDTILAGGSFGRRAQQTTHQAIELAEVAKAIGPG
EECCCCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCC
KALKLVWTREDDMRGGYYRPFGVHRMRGVVRDGRIEGWTDTIVGQSIMKGSPFEAMTFKD
CEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEECC
GMDATAYEGSNEPPYEIANFRCDLHQVDLGVPVLWWRSVGHTHTGYAVEAFVDELLTATG
CCCCCCCCCCCCCCHHHHHEEECEEEECCCCCEEEHHCCCCCCCCHHHHHHHHHHHHHCC
QDPVEGRLALMGNRKPRHAGVLKAVAELSNWKGAKPEAGRARGVAVVESFNTFVAQVVEL
CCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
SMSADGPVVHKVWCAVDCGVPVNPDIIRAQMEGGIGFALGHILYAQQPIEAGAPVSGNFD
HCCCCCCEEEEEEEEEECCCCCCHHHEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCH
TYRSLRINEMPQIEVTIIPSTEKPTGVGEPGVPPLGPAVANAMAKLGLPRPRKLPIVPGA
HHHEEEECCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCC
NA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]