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The map label for this gene is yngJ [H]

Identifier: 86749380

GI number: 86749380

Start: 2607970

End: 2609202

Strand: Direct

Name: yngJ [H]

Synonym: RPB_2260

Alternate gene names: 86749380

Gene position: 2607970-2609202 (Clockwise)

Preceding gene: 86749378

Following gene: 86749381

Centisome position: 48.91

GC content: 63.91

Gene sequence:

>1233_bases
ATGGATTTCACGATGTCCGATCGCCAGCGCGAATGGCTGGACCGCGTCACCGCCTTCATGAACACGCATGTCCGGCCGGC
GGTGCCGATCTACAAGCAGCAGGATGCCGAGGGCGACCGCTGGAAGGTGATTCCGATCCTCGAGGATCTGAAGAAGAAGG
CCAAGGCCGAGGGCCTGTGGAACATGTTCATGCCGCCGTCGTCGCACGAAGACGACGAATTCCGCGGCGCCGGCCTCACC
AATCTCGAATACGCGCTGCTGTCCGAGCAGATGGGCCATATCAGCTGGGCCTCCGAGGTGTTCAACTGCTCGGCGCCCGA
CACCGGCAACATGGAAGTGCTGATGCGCTACGGCTCCAAGGAGCACAAGCGGCAGTGGCTGCGTCCCCTGATGGACGGCG
AGATCCGTTCGGCATTTCTGATGACCGAACCCGCCGTGGCGTCGTCGGACGCCACCAACATCGAGACCCGGATCGAGCGC
GACGGTGATCACTACGTCATCAACGGCCGCAAATGGTGGTCGTCGGGCGTCGGCGATCCGCGCTGCAAGATCGCGATCGT
GATGGGCAAGACCGATCCGAACGCGGCCAAGCATCAGGCGCAGTCGCAGATCCTGGTGCCGCTCGATACCCCCGGCATCA
CCATCGAAAAGATGCTGCCGGTGTTCGGCTTCGACGACGCGCCGCACGGCCACGGCCAGGTGCTGCTCAAGGATGTCCGC
GTGCCGGTGTCGAACCTGCTGCTCGGCGAAGGCCGCGGTTTCGAAATCGCGCAGGGCCGTCTCGGTCCGGGCCGGATTCA
TCACTGCATGCGCACCATCGGCAAGGCCGAAGAGGCGTTGGAGAAGATGGTGCGGCGGCTGCAGTCGCGCACCGCCTTCG
GCAAGAAGATCATCGAATACTCGATCTGGGAACAGCGCATCGCCGAGGCGCGGACCGACATCGAGATGACCCGGCTGCTG
TGCCTCAAGGCCGCCGACATGATGGACAAGGTCGGCAACAAGACCGCCCAGCTCGAGATCGCGATGATCAAGGTTGCGGC
GCCGAACATGGCGCTGAAGATCATCGACAACGCGATCCAAGCGTTCGGCGGCGGCGGTGTCTCCGATGAAGCCGGCCTGG
CCAAGGATTACGCCAACATCCGCACGCTTCGGCTCGCGGACGGCCCGGACGAGGTGCACAACCGCGCCATTGCCCGGCTC
GAGATGAAGAAATACGCCAACGCGGCGCACTGA

Upstream 100 bases:

>100_bases
CCGCAGCGCGCAACGCAGAATAGGCTTGCGGAGGCGGAGCGGTGGGGAGACAGTGCCGGCAACCCGTCGGCCGAACAGGG
AAAACAGTGAGGATCGCCTG

Downstream 100 bases:

>100_bases
CCGCGCAGGCCGCATAAAAACATCATCGCCGGACTTGATCCGGCGATCCATCTCTTGAAAAGATGGATACCCGGGTCAAG
CCCGGGTATGACTGTTTCTG

Product: Acyl-CoA dehydrogenase-like

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MDFTMSDRQREWLDRVTAFMNTHVRPAVPIYKQQDAEGDRWKVIPILEDLKKKAKAEGLWNMFMPPSSHEDDEFRGAGLT
NLEYALLSEQMGHISWASEVFNCSAPDTGNMEVLMRYGSKEHKRQWLRPLMDGEIRSAFLMTEPAVASSDATNIETRIER
DGDHYVINGRKWWSSGVGDPRCKIAIVMGKTDPNAAKHQAQSQILVPLDTPGITIEKMLPVFGFDDAPHGHGQVLLKDVR
VPVSNLLLGEGRGFEIAQGRLGPGRIHHCMRTIGKAEEALEKMVRRLQSRTAFGKKIIEYSIWEQRIAEARTDIEMTRLL
CLKAADMMDKVGNKTAQLEIAMIKVAAPNMALKIIDNAIQAFGGGGVSDEAGLAKDYANIRTLRLADGPDEVHNRAIARL
EMKKYANAAH

Sequences:

>Translated_410_residues
MDFTMSDRQREWLDRVTAFMNTHVRPAVPIYKQQDAEGDRWKVIPILEDLKKKAKAEGLWNMFMPPSSHEDDEFRGAGLT
NLEYALLSEQMGHISWASEVFNCSAPDTGNMEVLMRYGSKEHKRQWLRPLMDGEIRSAFLMTEPAVASSDATNIETRIER
DGDHYVINGRKWWSSGVGDPRCKIAIVMGKTDPNAAKHQAQSQILVPLDTPGITIEKMLPVFGFDDAPHGHGQVLLKDVR
VPVSNLLLGEGRGFEIAQGRLGPGRIHHCMRTIGKAEEALEKMVRRLQSRTAFGKKIIEYSIWEQRIAEARTDIEMTRLL
CLKAADMMDKVGNKTAQLEIAMIKVAAPNMALKIIDNAIQAFGGGGVSDEAGLAKDYANIRTLRLADGPDEVHNRAIARL
EMKKYANAAH
>Mature_410_residues
MDFTMSDRQREWLDRVTAFMNTHVRPAVPIYKQQDAEGDRWKVIPILEDLKKKAKAEGLWNMFMPPSSHEDDEFRGAGLT
NLEYALLSEQMGHISWASEVFNCSAPDTGNMEVLMRYGSKEHKRQWLRPLMDGEIRSAFLMTEPAVASSDATNIETRIER
DGDHYVINGRKWWSSGVGDPRCKIAIVMGKTDPNAAKHQAQSQILVPLDTPGITIEKMLPVFGFDDAPHGHGQVLLKDVR
VPVSNLLLGEGRGFEIAQGRLGPGRIHHCMRTIGKAEEALEKMVRRLQSRTAFGKKIIEYSIWEQRIAEARTDIEMTRLL
CLKAADMMDKVGNKTAQLEIAMIKVAAPNMALKIIDNAIQAFGGGGVSDEAGLAKDYANIRTLRLADGPDEVHNRAIARL
EMKKYANAAH

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI211971008, Length=400, Percent_Identity=55.5, Blast_Score=457, Evalue=1e-129,
Organism=Homo sapiens, GI48976061, Length=400, Percent_Identity=55.5, Blast_Score=457, Evalue=1e-129,
Organism=Homo sapiens, GI38505218, Length=410, Percent_Identity=53.4146341463415, Blast_Score=432, Evalue=1e-121,
Organism=Homo sapiens, GI4557233, Length=377, Percent_Identity=30.2387267904509, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI4557231, Length=414, Percent_Identity=25.6038647342995, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI187960098, Length=414, Percent_Identity=25.6038647342995, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI4501859, Length=332, Percent_Identity=26.8072289156627, Blast_Score=126, Evalue=5e-29,
Organism=Homo sapiens, GI226958412, Length=398, Percent_Identity=25.1256281407035, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI226958414, Length=330, Percent_Identity=26.3636363636364, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI7656849, Length=366, Percent_Identity=26.5027322404372, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI76496475, Length=393, Percent_Identity=27.2264631043257, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI21361497, Length=406, Percent_Identity=24.8768472906404, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI4557235, Length=393, Percent_Identity=27.2264631043257, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI4501857, Length=316, Percent_Identity=26.2658227848101, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI4503943, Length=328, Percent_Identity=23.1707317073171, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI7669494, Length=309, Percent_Identity=23.6245954692557, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI87081958, Length=315, Percent_Identity=26.984126984127, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786223, Length=406, Percent_Identity=22.9064039408867, Blast_Score=79, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17562446, Length=403, Percent_Identity=50.6203473945409, Blast_Score=392, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI17534899, Length=409, Percent_Identity=27.3838630806846, Blast_Score=138, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI71985184, Length=404, Percent_Identity=27.4752475247525, Blast_Score=131, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI17569725, Length=415, Percent_Identity=26.5060240963855, Blast_Score=131, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI17570075, Length=413, Percent_Identity=24.6973365617433, Blast_Score=121, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI17506239, Length=402, Percent_Identity=26.1194029850746, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17533517, Length=329, Percent_Identity=27.6595744680851, Blast_Score=118, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17505929, Length=337, Percent_Identity=26.7062314540059, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17551932, Length=330, Percent_Identity=25.4545454545455, Blast_Score=111, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17538396, Length=360, Percent_Identity=25.2777777777778, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17508101, Length=338, Percent_Identity=25.4437869822485, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71985192, Length=351, Percent_Identity=26.2108262108262, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71990804, Length=259, Percent_Identity=28.957528957529, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI32563615, Length=234, Percent_Identity=26.0683760683761, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71982178, Length=306, Percent_Identity=24.8366013071895, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17534353, Length=289, Percent_Identity=24.5674740484429, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21356377, Length=336, Percent_Identity=30.6547619047619, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24660351, Length=399, Percent_Identity=27.0676691729323, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24646207, Length=333, Percent_Identity=30.03003003003, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24666513, Length=336, Percent_Identity=27.3809523809524, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI281363737, Length=336, Percent_Identity=28.2738095238095, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21355753, Length=401, Percent_Identity=23.9401496259352, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI19920834, Length=327, Percent_Identity=23.8532110091743, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 45887; Mature: 45887

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS00073 ACYL_COA_DH_2 ; PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFTMSDRQREWLDRVTAFMNTHVRPAVPIYKQQDAEGDRWKVIPILEDLKKKAKAEGLW
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCC
NMFMPPSSHEDDEFRGAGLTNLEYALLSEQMGHISWASEVFNCSAPDTGNMEVLMRYGSK
EECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHHEECCCH
EHKRQWLRPLMDGEIRSAFLMTEPAVASSDATNIETRIERDGDHYVINGRKWWSSGVGDP
HHHHHHHHHHHCCHHHHEEEEECCCCCCCCCCCCHHHEECCCCEEEECCCCHHCCCCCCC
RCKIAIVMGKTDPNAAKHQAQSQILVPLDTPGITIEKMLPVFGFDDAPHGHGQVLLKDVR
CEEEEEEEECCCCCHHHHHHHCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCCEEEEHHH
VPVSNLLLGEGRGFEIAQGRLGPGRIHHCMRTIGKAEEALEKMVRRLQSRTAFGKKIIEY
CCHHHHEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIWEQRIAEARTDIEMTRLLCLKAADMMDKVGNKTAQLEIAMIKVAAPNMALKIIDNAIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCHHHHHHHHHHH
AFGGGGVSDEAGLAKDYANIRTLRLADGPDEVHNRAIARLEMKKYANAAH
HHCCCCCCCCCHHHHHHHCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDFTMSDRQREWLDRVTAFMNTHVRPAVPIYKQQDAEGDRWKVIPILEDLKKKAKAEGLW
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCC
NMFMPPSSHEDDEFRGAGLTNLEYALLSEQMGHISWASEVFNCSAPDTGNMEVLMRYGSK
EECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHHEECCCH
EHKRQWLRPLMDGEIRSAFLMTEPAVASSDATNIETRIERDGDHYVINGRKWWSSGVGDP
HHHHHHHHHHHCCHHHHEEEEECCCCCCCCCCCCHHHEECCCCEEEECCCCHHCCCCCCC
RCKIAIVMGKTDPNAAKHQAQSQILVPLDTPGITIEKMLPVFGFDDAPHGHGQVLLKDVR
CEEEEEEEECCCCCHHHHHHHCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCCEEEEHHH
VPVSNLLLGEGRGFEIAQGRLGPGRIHHCMRTIGKAEEALEKMVRRLQSRTAFGKKIIEY
CCHHHHEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIWEQRIAEARTDIEMTRLLCLKAADMMDKVGNKTAQLEIAMIKVAAPNMALKIIDNAIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCHHHHHHHHHHH
AFGGGGVSDEAGLAKDYANIRTLRLADGPDEVHNRAIARLEMKKYANAAH
HHCCCCCCCCCHHHHHHHCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]