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The map label for this gene is tolQ [H]

Identifier: 86748932

GI number: 86748932

Start: 2069116

End: 2069829

Strand: Direct

Name: tolQ [H]

Synonym: RPB_1809

Alternate gene names: 86748932

Gene position: 2069116-2069829 (Clockwise)

Preceding gene: 86748931

Following gene: 86748933

Centisome position: 38.81

GC content: 64.43

Gene sequence:

>714_bases
ATGAACCCGGCCGACGTGACTCAGTCAGCCATGCCGCTGGTGTCCGCCGACATGTCGCTGATCGGACTGTTCTGGCAGGC
CCACTGGATCGTCAAATCGGTGATGCTGGGACTGATCGGCTGCTCGGTCTGGGTCTGGGCGATCGCGATCGACAAGCTGA
TCCTCTATTCCCGCACCAAGCGCGCGATGGACCGCTTCGAGCAGGCGTTCTGGTCCGGCGAGTCGATCGACGATTTGTAC
CGCACCCTGTCGGCCAAGCCGACGCATTCGATGGCGGCCTGCTTCGTCGCGGCGATGCGCGAGTGGAAGCGGTCGTTCGA
AAGCCATTCGCGCTCCTTCGCCGGCCTGCAGATGCGGATCGAGAAGGTGATGAACGTCTCGATCGCGCGCGAAGTCGAAC
GGCTGGAGCGACGGCTGCTGGTGCTGGCGACGGTCGGCTCCGCCGGTCCGTTCGTCGGCCTGTTCGGCACCGTCTGGGGC
ATCATGTCGAGCTTCCAGTCGATCGCCGCGTCCAAGAACACCTCCCTGGCGGTGGTCGCCCCCGGCATCGCCGAGGCGCT
GTTCGCCACTGCCATCGGCCTGATCGCCGCAATTCCGGCGACAATTTTCTATAACAAGTTCACGTCCGAGGTGAACCGCC
AGACCCAGCGGCTGGAGGGTTTCGCGGACGAGTTCTCGGCCATCCTGTCGCGGCAGATCGACGAGCGCGCATGA

Upstream 100 bases:

>100_bases
GGCGGCAGCGCTTCTTGCCAGAACGGCGCATGGCTGCGGGGAACCGGGGCCGGCGCCAGATCGGCTCCCGCCGCACCCCT
TGCGTGAGAGGATAATCGAC

Downstream 100 bases:

>100_bases
GCCGGATGAAGGTGAGCGCAAGGTGAGTCCCAGACCATGTCGATGAACCTAGCGGCAGGCGGCGGAGGCGGCGGCAGACG
TCGCCGGGGCAAGCGCCCGG

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MNPADVTQSAMPLVSADMSLIGLFWQAHWIVKSVMLGLIGCSVWVWAIAIDKLILYSRTKRAMDRFEQAFWSGESIDDLY
RTLSAKPTHSMAACFVAAMREWKRSFESHSRSFAGLQMRIEKVMNVSIAREVERLERRLLVLATVGSAGPFVGLFGTVWG
IMSSFQSIAASKNTSLAVVAPGIAEALFATAIGLIAAIPATIFYNKFTSEVNRQTQRLEGFADEFSAILSRQIDERA

Sequences:

>Translated_237_residues
MNPADVTQSAMPLVSADMSLIGLFWQAHWIVKSVMLGLIGCSVWVWAIAIDKLILYSRTKRAMDRFEQAFWSGESIDDLY
RTLSAKPTHSMAACFVAAMREWKRSFESHSRSFAGLQMRIEKVMNVSIAREVERLERRLLVLATVGSAGPFVGLFGTVWG
IMSSFQSIAASKNTSLAVVAPGIAEALFATAIGLIAAIPATIFYNKFTSEVNRQTQRLEGFADEFSAILSRQIDERA
>Mature_237_residues
MNPADVTQSAMPLVSADMSLIGLFWQAHWIVKSVMLGLIGCSVWVWAIAIDKLILYSRTKRAMDRFEQAFWSGESIDDLY
RTLSAKPTHSMAACFVAAMREWKRSFESHSRSFAGLQMRIEKVMNVSIAREVERLERRLLVLATVGSAGPFVGLFGTVWG
IMSSFQSIAASKNTSLAVVAPGIAEALFATAIGLIAAIPATIFYNKFTSEVNRQTQRLEGFADEFSAILSRQIDERA

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=218, Percent_Identity=41.2844036697248, Blast_Score=159, Evalue=1e-40,
Organism=Escherichia coli, GI1789381, Length=227, Percent_Identity=37.4449339207048, Blast_Score=133, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014163 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 26236; Mature: 26236

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPADVTQSAMPLVSADMSLIGLFWQAHWIVKSVMLGLIGCSVWVWAIAIDKLILYSRTK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAMDRFEQAFWSGESIDDLYRTLSAKPTHSMAACFVAAMREWKRSFESHSRSFAGLQMRI
HHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKVMNVSIAREVERLERRLLVLATVGSAGPFVGLFGTVWGIMSSFQSIAASKNTSLAVVA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
PGIAEALFATAIGLIAAIPATIFYNKFTSEVNRQTQRLEGFADEFSAILSRQIDERA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNPADVTQSAMPLVSADMSLIGLFWQAHWIVKSVMLGLIGCSVWVWAIAIDKLILYSRTK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAMDRFEQAFWSGESIDDLYRTLSAKPTHSMAACFVAAMREWKRSFESHSRSFAGLQMRI
HHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKVMNVSIAREVERLERRLLVLATVGSAGPFVGLFGTVWGIMSSFQSIAASKNTSLAVVA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
PGIAEALFATAIGLIAAIPATIFYNKFTSEVNRQTQRLEGFADEFSAILSRQIDERA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8955385; 10984043 [H]