Click here to switch to the map view.

The map label for this gene is gap3 [H]

Identifier: 86748765

GI number: 86748765

Start: 1871951

End: 1872994

Strand: Direct

Name: gap3 [H]

Synonym: RPB_1642

Alternate gene names: 86748765

Gene position: 1871951-1872994 (Clockwise)

Preceding gene: 86748764

Following gene: 86748766

Centisome position: 35.11

GC content: 63.89

Gene sequence:

>1044_bases
ATGAAGGTCGGCATCAACGGCATGGGCCGGATCGGACGATTGGCGCTGCGCGCGGCACTCGGCGGAATTCGGCGACCTGA
CAACGATCCGCGCGGGGACAACCGCCTGGACGTCGTCCATGTCAACGAACTCAAGGGTGGCATCGCCGCCACCGCTCATC
TGCTCGAATTCGATAGCGTGCACGGGCGCTGGCACCAGCCGATCGCGGTGGAATCCGACCGCGTGATAGCGCTCGGCACC
CAGCGGATCGGTTTCAGCGAGCACGCTGCGCCCGCTGACGTCGCATGGGGCGATCTCGGATGCGATGTGGTGTTGGAATG
CACCGGGAAGTTCCTCACGCCCGCTCAGTTGCAAGGCTATTTCGACCGCGGTGTGAAACGGGTGATCGTCGCCGCACCGG
TCAAGGACGAGGCCGCCCTCAACATCGTGGTCGGCGTCAACGACAAGCTCTACGAGCCGCAGCGGCACCGGCTGCTGACA
GCGGCCTCCTGCACCACCAATTGCCTCGCGCCGGTGGTGAAGGTGATCCACGAATCGATCGGAATCCGGCACGGCCAGAT
CACGACCATTCATGACCCGACCAACACCAACGTGGTGGTCGATGCGCCGCACAAGGATCTGCGTCGCGCACGCTCTGCGA
TGCTGTCGCTGCAGCCGACCACGACGGGCAGTGCCACCGCGATCGCATTGATCTATCCCGAGTTGAAAGGGAAGCTGAAC
GGCCACGCGGTCCGCGCGCCCGTTCTGAATGCCAGCCTGACCGATTGTGTGTTCGAACTGAACCGGCCGACCTCGGTCGA
GGAGGTCAACGCCCTGTTCAAATCGGCGTCGGAGGGCGTGCTGGCGGGCATTCTCGGCTATGAGACACGACCGCTGGTGT
CGGCCGACTACACCAATGATTCCCGCAGTTCGATCGTCGATGCGCTGAGCACCATGGTGACCGACGAGACGTTGCTGAAG
GTCTATGCCTGGTACGACAACGAGGTCGGCTATGCCTGCCGGATGGTCGACCTCGCCGCCATCGTGCAACGCGCGGGCGT
CTGA

Upstream 100 bases:

>100_bases
TTCACCAGCCTGCCGTTCGAGTCGCTCGACCGAATGGCGGTGAAGGCCCGCCTCGATGAAATCGGCGACACCAACCTCGT
CAAGCCCTGAAGGAACTCCC

Downstream 100 bases:

>100_bases
CCATGGTCCGCAACTACGTCATCGTCACGGCCTCCTATTGGGGCTTCACGCTGGTCGACGGCGCGTTGCGGATGCTGGTG
CTATTTCACTTCTTCCGACT

Product: glyceraldehyde-3-phosphate dehydrogenase, type I

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MKVGINGMGRIGRLALRAALGGIRRPDNDPRGDNRLDVVHVNELKGGIAATAHLLEFDSVHGRWHQPIAVESDRVIALGT
QRIGFSEHAAPADVAWGDLGCDVVLECTGKFLTPAQLQGYFDRGVKRVIVAAPVKDEAALNIVVGVNDKLYEPQRHRLLT
AASCTTNCLAPVVKVIHESIGIRHGQITTIHDPTNTNVVVDAPHKDLRRARSAMLSLQPTTTGSATAIALIYPELKGKLN
GHAVRAPVLNASLTDCVFELNRPTSVEEVNALFKSASEGVLAGILGYETRPLVSADYTNDSRSSIVDALSTMVTDETLLK
VYAWYDNEVGYACRMVDLAAIVQRAGV

Sequences:

>Translated_347_residues
MKVGINGMGRIGRLALRAALGGIRRPDNDPRGDNRLDVVHVNELKGGIAATAHLLEFDSVHGRWHQPIAVESDRVIALGT
QRIGFSEHAAPADVAWGDLGCDVVLECTGKFLTPAQLQGYFDRGVKRVIVAAPVKDEAALNIVVGVNDKLYEPQRHRLLT
AASCTTNCLAPVVKVIHESIGIRHGQITTIHDPTNTNVVVDAPHKDLRRARSAMLSLQPTTTGSATAIALIYPELKGKLN
GHAVRAPVLNASLTDCVFELNRPTSVEEVNALFKSASEGVLAGILGYETRPLVSADYTNDSRSSIVDALSTMVTDETLLK
VYAWYDNEVGYACRMVDLAAIVQRAGV
>Mature_347_residues
MKVGINGMGRIGRLALRAALGGIRRPDNDPRGDNRLDVVHVNELKGGIAATAHLLEFDSVHGRWHQPIAVESDRVIALGT
QRIGFSEHAAPADVAWGDLGCDVVLECTGKFLTPAQLQGYFDRGVKRVIVAAPVKDEAALNIVVGVNDKLYEPQRHRLLT
AASCTTNCLAPVVKVIHESIGIRHGQITTIHDPTNTNVVVDAPHKDLRRARSAMLSLQPTTTGSATAIALIYPELKGKLN
GHAVRAPVLNASLTDCVFELNRPTSVEEVNALFKSASEGVLAGILGYETRPLVSADYTNDSRSSIVDALSTMVTDETLLK
VYAWYDNEVGYACRMVDLAAIVQRAGV

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=341, Percent_Identity=38.7096774193548, Blast_Score=249, Evalue=4e-66,
Organism=Homo sapiens, GI7657116, Length=339, Percent_Identity=36.5781710914454, Blast_Score=223, Evalue=2e-58,
Organism=Escherichia coli, GI1788079, Length=345, Percent_Identity=37.6811594202899, Blast_Score=238, Evalue=5e-64,
Organism=Escherichia coli, GI1789295, Length=337, Percent_Identity=36.4985163204748, Blast_Score=224, Evalue=8e-60,
Organism=Caenorhabditis elegans, GI17568413, Length=348, Percent_Identity=38.5057471264368, Blast_Score=238, Evalue=4e-63,
Organism=Caenorhabditis elegans, GI32566163, Length=348, Percent_Identity=38.5057471264368, Blast_Score=238, Evalue=4e-63,
Organism=Caenorhabditis elegans, GI17534677, Length=352, Percent_Identity=38.0681818181818, Blast_Score=234, Evalue=4e-62,
Organism=Caenorhabditis elegans, GI17534679, Length=352, Percent_Identity=37.7840909090909, Blast_Score=233, Evalue=9e-62,
Organism=Saccharomyces cerevisiae, GI6321631, Length=346, Percent_Identity=38.150289017341, Blast_Score=243, Evalue=3e-65,
Organism=Saccharomyces cerevisiae, GI6322468, Length=346, Percent_Identity=38.150289017341, Blast_Score=243, Evalue=4e-65,
Organism=Saccharomyces cerevisiae, GI6322409, Length=346, Percent_Identity=37.8612716763006, Blast_Score=242, Evalue=5e-65,
Organism=Drosophila melanogaster, GI19922412, Length=342, Percent_Identity=36.8421052631579, Blast_Score=244, Evalue=8e-65,
Organism=Drosophila melanogaster, GI17933600, Length=343, Percent_Identity=38.4839650145773, Blast_Score=234, Evalue=5e-62,
Organism=Drosophila melanogaster, GI18110149, Length=343, Percent_Identity=38.4839650145773, Blast_Score=234, Evalue=5e-62,
Organism=Drosophila melanogaster, GI85725000, Length=343, Percent_Identity=38.7755102040816, Blast_Score=234, Evalue=9e-62,
Organism=Drosophila melanogaster, GI22023983, Length=343, Percent_Identity=38.7755102040816, Blast_Score=234, Evalue=9e-62,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 37366; Mature: 37366

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVGINGMGRIGRLALRAALGGIRRPDNDPRGDNRLDVVHVNELKGGIAATAHLLEFDSV
CEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEHHHCCCHHHHHHHHHHHCC
HGRWHQPIAVESDRVIALGTQRIGFSEHAAPADVAWGDLGCDVVLECTGKFLTPAQLQGY
CCCCCCCEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHH
FDRGVKRVIVAAPVKDEAALNIVVGVNDKLYEPQRHRLLTAASCTTNCLAPVVKVIHESI
HHCCCEEEEEECCCCCCCEEEEEEECCCCCCCCHHHHEEEEHHHHHHHHHHHHHHHHHHH
GIRHGQITTIHDPTNTNVVVDAPHKDLRRARSAMLSLQPTTTGSATAIALIYPELKGKLN
CCCCCEEEEEECCCCCCEEEECCHHHHHHHHHHHEEECCCCCCCCEEEEEEEECCCCCCC
GHAVRAPVLNASLTDCVFELNRPTSVEEVNALFKSASEGVLAGILGYETRPLVSADYTND
CCEEECCCCCCHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEHHHCCCCCCCEEECCCCC
SRSSIVDALSTMVTDETLLKVYAWYDNEVGYACRMVDLAAIVQRAGV
HHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKVGINGMGRIGRLALRAALGGIRRPDNDPRGDNRLDVVHVNELKGGIAATAHLLEFDSV
CEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEHHHCCCHHHHHHHHHHHCC
HGRWHQPIAVESDRVIALGTQRIGFSEHAAPADVAWGDLGCDVVLECTGKFLTPAQLQGY
CCCCCCCEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHH
FDRGVKRVIVAAPVKDEAALNIVVGVNDKLYEPQRHRLLTAASCTTNCLAPVVKVIHESI
HHCCCEEEEEECCCCCCCEEEEEEECCCCCCCCHHHHEEEEHHHHHHHHHHHHHHHHHHH
GIRHGQITTIHDPTNTNVVVDAPHKDLRRARSAMLSLQPTTTGSATAIALIYPELKGKLN
CCCCCEEEEEECCCCCCEEEECCHHHHHHHHHHHEEECCCCCCCCEEEEEEEECCCCCCC
GHAVRAPVLNASLTDCVFELNRPTSVEEVNALFKSASEGVLAGILGYETRPLVSADYTND
CCEEECCCCCCHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEHHHCCCCCCCEEECCCCC
SRSSIVDALSTMVTDETLLKVYAWYDNEVGYACRMVDLAAIVQRAGV
HHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8378350 [H]