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The map label for this gene is xanB [H]

Identifier: 86748649

GI number: 86748649

Start: 1716461

End: 1717873

Strand: Reverse

Name: xanB [H]

Synonym: RPB_1524

Alternate gene names: 86748649

Gene position: 1717873-1716461 (Counterclockwise)

Preceding gene: 86748654

Following gene: 86748648

Centisome position: 32.22

GC content: 62.35

Gene sequence:

>1413_bases
ATGACCAAGAAGATCACCCCCCTTATCATGTGTGGCGGGGCCGGAACACGATTGTGGCCGGCTTCCCGCGAGGTCCGCCC
CAAGCAATTCCTACCGTTGTTCGGACCACGTTCGACCTTTCAGGATACCCTGCTCAGGGTAGCCGATTCGACCTTGTTCG
GACGACCGATTGTGATCACCAGCGTGGCCTATCGGTTCATGGTTCGCGAGCAGCTCGCGGAGCTCGGCCTCGACGCCGAT
GTCCTGCTCGAACCTTCGCGGCGGGATTCCGGCCCGGCAATCGCCGCGGGCGCCGTGTTCGCGCAGCAGCAAGACACCGA
CGCGGTCGTCCTGGCGCTCGCCGCAGATCACGTCGTTCGCGACAACCCGGCATTCGTCGAGGCTTGCCGCAAGGGTCTTT
CGGCGGCCAATTCCGGGCGGATTGTCACTTTCGGCGTGAACCCCGATCGTGCCGCGACGGAATACGGCTATATCAGCGCA
GGCGACGCGATCGCCGACGATGTCCGCGCCGTGGAGAGATTCGTCGAAAAGCCGGACGCCGCGACGGCGGCCGACTATTT
CCGGCTCGGCTATCTCTGGAACAGCGGAAACTTCATGTTTCGCGCGGACATCCTGCTCGACGAGTATCGCAACCTCGACG
CCGAAAGCGTGCAGACGATTTCCGACGCAGTATCCTTGGCGGGACAGGATCTCGGCTTCGTCACGCTCGAACCGGATGCG
TTCGGCAAGGCCAAATCGATCTCGATCGACTACGCCGTGATGGAGAAGACCAAGCTCGCTGCGGTCGTCCCGGTGTCGTG
CGGCTGGTCCGACGTCGGCTCCTGGCACGCGGTGTGGGAACTGTCGCAGAAGGACGAGAGCGGTAACGCCGCGCAAGGCA
CGGCCGTGTTCGAGGACTGCCGCAACTGCAACGTTTCGACAGACGGCACGCTGGTGGCGCTCGAAGGCGTCGATGATCTG
GTCGTCGTGGCGACGCAGGACGCCGTTCTGGTTTCTCGTCAAAAGGACGCGAACGGGCTCAAGCGGCTGGTCGCGAAGCT
CAGGACGGTCGCCCCCGAAGTGACCGATCACCACCTCAAGGTCCACCGTCCTTGGGGATCGTACCAGTCGCTCGACAACG
GCGATCGTCACCAGGTCAAACGCATCATCGTCAAGGCTGGAGAACGCTTGTCGTTGCAGAAGCACCACCATCGTTCCGAG
CACTGGATCGTGGTGCGCGGCGCGGCGCTGGTGACGATCAACGACAGCTTCAAGACTATTCACGAAAACGAATCGATCTA
CATCCCGATCGGCGCAACCCACCGGCTGGAGAACCCCGGCAAGATTCCGCTGGAGCTGATCGAAGTCCAGACCGGCAGCT
ATCTCGGCGAGGACGACATCGTCAGAATCGAAGACGACTATCAACGCGCCTGA

Upstream 100 bases:

>100_bases
GCATGCCCCCATTCGATCAATCAAATAGGGAGGACGCACCCGATTGAGTTTGCCTTGCCTATTCGCAGTTGCTATTCAGG
GTCGCCTCAGGAATGGGACG

Downstream 100 bases:

>100_bases
TCCGAGAGCACCGGACGGGCGCAGGCGCCGACGATGGCGCCTCGCCGCGCTATCGCAGCCGGCGAGCCAAATCCGCGAAG
CTCAGAGATCTTTCATGTTT

Product: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase

Products: NA

Alternate protein names: Mannose-6-phosphate isomerase; Phosphohexomutase; Phosphomannose isomerase; PMI; Mannose-1-phosphate guanylyl transferase; GDP-mannose pyrophosphorylase; GMP; GMPP [H]

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MTKKITPLIMCGGAGTRLWPASREVRPKQFLPLFGPRSTFQDTLLRVADSTLFGRPIVITSVAYRFMVREQLAELGLDAD
VLLEPSRRDSGPAIAAGAVFAQQQDTDAVVLALAADHVVRDNPAFVEACRKGLSAANSGRIVTFGVNPDRAATEYGYISA
GDAIADDVRAVERFVEKPDAATAADYFRLGYLWNSGNFMFRADILLDEYRNLDAESVQTISDAVSLAGQDLGFVTLEPDA
FGKAKSISIDYAVMEKTKLAAVVPVSCGWSDVGSWHAVWELSQKDESGNAAQGTAVFEDCRNCNVSTDGTLVALEGVDDL
VVVATQDAVLVSRQKDANGLKRLVAKLRTVAPEVTDHHLKVHRPWGSYQSLDNGDRHQVKRIIVKAGERLSLQKHHHRSE
HWIVVRGAALVTINDSFKTIHENESIYIPIGATHRLENPGKIPLELIEVQTGSYLGEDDIVRIEDDYQRA

Sequences:

>Translated_470_residues
MTKKITPLIMCGGAGTRLWPASREVRPKQFLPLFGPRSTFQDTLLRVADSTLFGRPIVITSVAYRFMVREQLAELGLDAD
VLLEPSRRDSGPAIAAGAVFAQQQDTDAVVLALAADHVVRDNPAFVEACRKGLSAANSGRIVTFGVNPDRAATEYGYISA
GDAIADDVRAVERFVEKPDAATAADYFRLGYLWNSGNFMFRADILLDEYRNLDAESVQTISDAVSLAGQDLGFVTLEPDA
FGKAKSISIDYAVMEKTKLAAVVPVSCGWSDVGSWHAVWELSQKDESGNAAQGTAVFEDCRNCNVSTDGTLVALEGVDDL
VVVATQDAVLVSRQKDANGLKRLVAKLRTVAPEVTDHHLKVHRPWGSYQSLDNGDRHQVKRIIVKAGERLSLQKHHHRSE
HWIVVRGAALVTINDSFKTIHENESIYIPIGATHRLENPGKIPLELIEVQTGSYLGEDDIVRIEDDYQRA
>Mature_469_residues
TKKITPLIMCGGAGTRLWPASREVRPKQFLPLFGPRSTFQDTLLRVADSTLFGRPIVITSVAYRFMVREQLAELGLDADV
LLEPSRRDSGPAIAAGAVFAQQQDTDAVVLALAADHVVRDNPAFVEACRKGLSAANSGRIVTFGVNPDRAATEYGYISAG
DAIADDVRAVERFVEKPDAATAADYFRLGYLWNSGNFMFRADILLDEYRNLDAESVQTISDAVSLAGQDLGFVTLEPDAF
GKAKSISIDYAVMEKTKLAAVVPVSCGWSDVGSWHAVWELSQKDESGNAAQGTAVFEDCRNCNVSTDGTLVALEGVDDLV
VVATQDAVLVSRQKDANGLKRLVAKLRTVAPEVTDHHLKVHRPWGSYQSLDNGDRHQVKRIIVKAGERLSLQKHHHRSEH
WIVVRGAALVTINDSFKTIHENESIYIPIGATHRLENPGKIPLELIEVQTGSYLGEDDIVRIEDDYQRA

Specific function: Involved in xanthan production [H]

COG id: COG0836

COG function: function code M; Mannose-1-phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788362, Length=474, Percent_Identity=46.6244725738397, Blast_Score=402, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR006375
- InterPro:   IPR001538
- InterPro:   IPR005835
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01050 MannoseP_isomer; PF00483 NTP_transferase [H]

EC number: =5.3.1.8; =2.7.7.13 [H]

Molecular weight: Translated: 51494; Mature: 51362

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKITPLIMCGGAGTRLWPASREVRPKQFLPLFGPRSTFQDTLLRVADSTLFGRPIVIT
CCCCCCEEEEECCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHH
SVAYRFMVREQLAELGLDADVLLEPSRRDSGPAIAAGAVFAQQQDTDAVVLALAADHVVR
HHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEEEHHEEECCCCCCEEEEEEEHHHHCC
DNPAFVEACRKGLSAANSGRIVTFGVNPDRAATEYGYISAGDAIADDVRAVERFVEKPDA
CCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCC
ATAADYFRLGYLWNSGNFMFRADILLDEYRNLDAESVQTISDAVSLAGQDLGFVTLEPDA
CHHHHHEEEEEEECCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCCC
FGKAKSISIDYAVMEKTKLAAVVPVSCGWSDVGSWHAVWELSQKDESGNAAQGTAVFEDC
CCCCEEEEEEHEECCCCEEEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHH
RNCNVSTDGTLVALEGVDDLVVVATQDAVLVSRQKDANGLKRLVAKLRTVAPEVTDHHLK
HCCCCCCCCCEEEECCCCCEEEEEECCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEE
VHRPWGSYQSLDNGDRHQVKRIIVKAGERLSLQKHHHRSEHWIVVRGAALVTINDSFKTI
EECCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHCCCCCCEEEEECEEEEEECCCCCEE
HENESIYIPIGATHRLENPGKIPLELIEVQTGSYLGEDDIVRIEDDYQRA
ECCCEEEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEECCCCCCC
>Mature Secondary Structure 
TKKITPLIMCGGAGTRLWPASREVRPKQFLPLFGPRSTFQDTLLRVADSTLFGRPIVIT
CCCCCEEEEECCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHH
SVAYRFMVREQLAELGLDADVLLEPSRRDSGPAIAAGAVFAQQQDTDAVVLALAADHVVR
HHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEEEHHEEECCCCCCEEEEEEEHHHHCC
DNPAFVEACRKGLSAANSGRIVTFGVNPDRAATEYGYISAGDAIADDVRAVERFVEKPDA
CCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCC
ATAADYFRLGYLWNSGNFMFRADILLDEYRNLDAESVQTISDAVSLAGQDLGFVTLEPDA
CHHHHHEEEEEEECCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCCC
FGKAKSISIDYAVMEKTKLAAVVPVSCGWSDVGSWHAVWELSQKDESGNAAQGTAVFEDC
CCCCEEEEEEHEECCCCEEEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHH
RNCNVSTDGTLVALEGVDDLVVVATQDAVLVSRQKDANGLKRLVAKLRTVAPEVTDHHLK
HCCCCCCCCCEEEECCCCCEEEEEECCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEE
VHRPWGSYQSLDNGDRHQVKRIIVKAGERLSLQKHHHRSEHWIVVRGAALVTINDSFKTI
EECCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHCCCCCCEEEEECEEEEEECCCCCEE
HENESIYIPIGATHRLENPGKIPLELIEVQTGSYLGEDDIVRIEDDYQRA
ECCCEEEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370280; 11589581 [H]