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The map label for this gene is pntAB [H]

Identifier: 86748561

GI number: 86748561

Start: 1625086

End: 1625409

Strand: Direct

Name: pntAB [H]

Synonym: RPB_1436

Alternate gene names: 86748561

Gene position: 1625086-1625409 (Clockwise)

Preceding gene: 86748560

Following gene: 86748562

Centisome position: 30.48

GC content: 62.04

Gene sequence:

>324_bases
ATGGAGCATGTCGTGCAGGCCGTCGATCCGTTCGTGTTTCGGCTGTCGATTTTCGTTCTGGCCGTGTTCGTCGGCTATTT
CGTGGTGTGGGCGGTGACGCCCGCGCTGCACACCCCGCTGATGTCGGTGACCAACGCGATCTCCTCGGTGATCGTGGTCG
GCGCGTTGCTGGCGGTCGGCGTGTCGCTGGTCGGCAGCGACAACGGTCCGCTGTGGGCGCGTGGCTTCGGCTTCGTCGCG
CTGATCTTCGCGTGTATCAACATCTTCGGCGGTTTCCTTGTCACCCAGCGCATGCTGGCGATGTACAAGAAGAAGCAGAA
GTGA

Upstream 100 bases:

>100_bases
GGCGGTGAATTGGGACGACGATCTGGTCAAGGCCACCGCGCTGACGCGCGACGGCGCCGTCGTTCACCCGAACTTCCAGC
CGAAATAAAGGAAAGCCGCC

Downstream 100 bases:

>100_bases
TTAGGGGCCGTCGATGAACGCCAATCTTTCCGCACTTCTGTATCTGATCGCCGGCGTCCTGTTCATTCTGTCGCTGCGTG
GTCTGTCGTCGCCGGCCACC

Product: nicotinamide nucleotide transhydrogenase, subunit alpha2

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit alpha 2; Proton-translocating transhydrogenase component 2; Pyridine nucleotide transhydrogenase subunit alpha 2; dII [H]

Number of amino acids: Translated: 107; Mature: 107

Protein sequence:

>107_residues
MEHVVQAVDPFVFRLSIFVLAVFVGYFVVWAVTPALHTPLMSVTNAISSVIVVGALLAVGVSLVGSDNGPLWARGFGFVA
LIFACINIFGGFLVTQRMLAMYKKKQK

Sequences:

>Translated_107_residues
MEHVVQAVDPFVFRLSIFVLAVFVGYFVVWAVTPALHTPLMSVTNAISSVIVVGALLAVGVSLVGSDNGPLWARGFGFVA
LIFACINIFGGFLVTQRMLAMYKKKQK
>Mature_107_residues
MEHVVQAVDPFVFRLSIFVLAVFVGYFVVWAVTPALHTPLMSVTNAISSVIVVGALLAVGVSLVGSDNGPLWARGFGFVA
LIFACINIFGGFLVTQRMLAMYKKKQK

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG3288

COG function: function code C; NAD/NADP transhydrogenase alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI122939155, Length=94, Percent_Identity=50, Blast_Score=86, Evalue=8e-18,
Organism=Homo sapiens, GI122939153, Length=94, Percent_Identity=50, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1787887, Length=99, Percent_Identity=54.5454545454545, Blast_Score=100, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17550456, Length=104, Percent_Identity=45.1923076923077, Blast_Score=89, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 11576; Mature: 11576

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHVVQAVDPFVFRLSIFVLAVFVGYFVVWAVTPALHTPLMSVTNAISSVIVVGALLAVG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSLVGSDNGPLWARGFGFVALIFACINIFGGFLVTQRMLAMYKKKQK
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEHVVQAVDPFVFRLSIFVLAVFVGYFVVWAVTPALHTPLMSVTNAISSVIVVGALLAVG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSLVGSDNGPLWARGFGFVALIFACINIFGGFLVTQRMLAMYKKKQK
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]