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The map label for this gene is pntB [H]

Identifier: 86748562

GI number: 86748562

Start: 1625423

End: 1626826

Strand: Direct

Name: pntB [H]

Synonym: RPB_1437

Alternate gene names: 86748562

Gene position: 1625423-1626826 (Clockwise)

Preceding gene: 86748561

Following gene: 86748565

Centisome position: 30.49

GC content: 65.38

Gene sequence:

>1404_bases
ATGAACGCCAATCTTTCCGCACTTCTGTATCTGATCGCCGGCGTCCTGTTCATTCTGTCGCTGCGTGGTCTGTCGTCGCC
GGCCACCAGCCGTCAGGGCAACCTGATGGGCATGACCGGCATGGGGATCGCGATCCTCACCACGCTGGCCGGCCATCCGC
CCGCCGACTTCCTCGGCTGGGTGCTCGTCATCCTCGGCATCGCCATCGGCGGCGGCATCGGCGCGGTGATCGCCAAGCGG
GTGCCGATGACCTCGATGCCCGAACTGGTCGCGGCCTTCCACTCGCTGGTCGGCATGGCCGCGGTGCTGGTCGCCGCCGG
CGCGTTCTATGCGCCCGCAGCCTTCGACATCGGCGTGCCCGGCAACATCCACGGCGCGAGCCTGGTCGAAATGTCGCTCG
GCGTCGCCATCGGTGCGCTGACCTTCACCGGCTCGGTGATCGCATTCCTCAAGCTGTCCGGCCGCATGAGCGGCGCGCCG
ATCATCTTGCCGGCGCGTCACGTGGTGAACATCACGCTCGGTGTCATCATGGTGGTTGCGATCATCGTGCTGGTGATCAC
CGGCCACGAATACGCCTTCTGGGTGATCACCGCCGTCGCGCTGCTGCTCGGCATCCTGATGATCATCCCGATCGGCGGCG
CCGACATGCCGGTCGTGATCTCGATGCTGAACTCGTATTCCGGCTGGGCCGCCGCCGGCATCGGCTTCACGCTCGGCAAC
TCGGCGCTGATCATCACCGGCGCGCTGGTCGGCTCCTCGGGCGCGATTCTGTCCTACATCATGTGCAAGGGCATGAACCG
CTCCTTCATCTCGGTGATCCTCGGCGGCTTCGGCGGCGAGACCGCGGCTGCCGGCGGTGGCGGTGGCGAACAGCGTCCGG
CCAAGCTCGGCTCGGCCGACGACGCCGCCTTCATCATGAAGAACGCCCAGAAGGTCATCATCGTGCCGGGCTACGGCATG
GCGGTGGCGCAGGCCCAGCACGCGCTGCGCGAGATGGCCGACACGCTGAAGAAGGAAGGCGTCGAGGTGAAGTACGCGAT
TCATCCGGTCGCCGGCCGTATGCCGGGCCACATGAACGTGCTGCTCGCCGAAGCCAACGTGCCCTACGACGAGGTGTTCG
AACTCGAGGACATCAACTCGGAATTCGCGCAGGCCGACGTGGCCTTCGTGATCGGCGCCAACGACGTCACCAACCCGGCC
GCCGAAGAGGATCCGACCTCGCCGATCTACGGCATGCCGGTGCTGCAGGTGTGGAAGGCCGGCACCGTGATGTTCATCAA
GCGGTCGCTGGCGTCGGGTTACGCCGGCATCGACAACCCGCTGTTCTATCGCGACAATACGATGATGCTGCTCGGCGACG
CCAAGAAGATGACCGAGAACATCGTCAAGGCGATGAATCACTAA

Upstream 100 bases:

>100_bases
GCGCTGATCTTCGCGTGTATCAACATCTTCGGCGGTTTCCTTGTCACCCAGCGCATGCTGGCGATGTACAAGAAGAAGCA
GAAGTGATTAGGGGCCGTCG

Downstream 100 bases:

>100_bases
TTCGACGAATCAAGACGCTTCGACGTCTCGAACGACAACGCCCGGCCGCAAGGCCGGGCGTTTTGCATTTGGGACATCGT
CGTTGCGAGGAGCACCCGGA

Product: NAD(P) transhydrogenase, beta subunit

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Proton-translocating transhydrogenase NADP(H)-binding component; Pyridine nucleotide transhydrogenase subunit beta; dIII [H]

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MNANLSALLYLIAGVLFILSLRGLSSPATSRQGNLMGMTGMGIAILTTLAGHPPADFLGWVLVILGIAIGGGIGAVIAKR
VPMTSMPELVAAFHSLVGMAAVLVAAGAFYAPAAFDIGVPGNIHGASLVEMSLGVAIGALTFTGSVIAFLKLSGRMSGAP
IILPARHVVNITLGVIMVVAIIVLVITGHEYAFWVITAVALLLGILMIIPIGGADMPVVISMLNSYSGWAAAGIGFTLGN
SALIITGALVGSSGAILSYIMCKGMNRSFISVILGGFGGETAAAGGGGGEQRPAKLGSADDAAFIMKNAQKVIIVPGYGM
AVAQAQHALREMADTLKKEGVEVKYAIHPVAGRMPGHMNVLLAEANVPYDEVFELEDINSEFAQADVAFVIGANDVTNPA
AEEDPTSPIYGMPVLQVWKAGTVMFIKRSLASGYAGIDNPLFYRDNTMMLLGDAKKMTENIVKAMNH

Sequences:

>Translated_467_residues
MNANLSALLYLIAGVLFILSLRGLSSPATSRQGNLMGMTGMGIAILTTLAGHPPADFLGWVLVILGIAIGGGIGAVIAKR
VPMTSMPELVAAFHSLVGMAAVLVAAGAFYAPAAFDIGVPGNIHGASLVEMSLGVAIGALTFTGSVIAFLKLSGRMSGAP
IILPARHVVNITLGVIMVVAIIVLVITGHEYAFWVITAVALLLGILMIIPIGGADMPVVISMLNSYSGWAAAGIGFTLGN
SALIITGALVGSSGAILSYIMCKGMNRSFISVILGGFGGETAAAGGGGGEQRPAKLGSADDAAFIMKNAQKVIIVPGYGM
AVAQAQHALREMADTLKKEGVEVKYAIHPVAGRMPGHMNVLLAEANVPYDEVFELEDINSEFAQADVAFVIGANDVTNPA
AEEDPTSPIYGMPVLQVWKAGTVMFIKRSLASGYAGIDNPLFYRDNTMMLLGDAKKMTENIVKAMNH
>Mature_467_residues
MNANLSALLYLIAGVLFILSLRGLSSPATSRQGNLMGMTGMGIAILTTLAGHPPADFLGWVLVILGIAIGGGIGAVIAKR
VPMTSMPELVAAFHSLVGMAAVLVAAGAFYAPAAFDIGVPGNIHGASLVEMSLGVAIGALTFTGSVIAFLKLSGRMSGAP
IILPARHVVNITLGVIMVVAIIVLVITGHEYAFWVITAVALLLGILMIIPIGGADMPVVISMLNSYSGWAAAGIGFTLGN
SALIITGALVGSSGAILSYIMCKGMNRSFISVILGGFGGETAAAGGGGGEQRPAKLGSADDAAFIMKNAQKVIIVPGYGM
AVAQAQHALREMADTLKKEGVEVKYAIHPVAGRMPGHMNVLLAEANVPYDEVFELEDINSEFAQADVAFVIGANDVTNPA
AEEDPTSPIYGMPVLQVWKAGTVMFIKRSLASGYAGIDNPLFYRDNTMMLLGDAKKMTENIVKAMNH

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG1282

COG function: function code C; NAD/NADP transhydrogenase beta subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNT beta subunit family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=471, Percent_Identity=45.859872611465, Blast_Score=381, Evalue=1e-106,
Organism=Homo sapiens, GI122939153, Length=471, Percent_Identity=45.859872611465, Blast_Score=381, Evalue=1e-106,
Organism=Escherichia coli, GI1787886, Length=471, Percent_Identity=54.140127388535, Blast_Score=481, Evalue=1e-137,
Organism=Caenorhabditis elegans, GI17550456, Length=464, Percent_Identity=46.1206896551724, Blast_Score=382, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012136
- InterPro:   IPR004003 [H]

Pfam domain/function: PF02233 PNTB [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 48281; Mature: 48281

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNANLSALLYLIAGVLFILSLRGLSSPATSRQGNLMGMTGMGIAILTTLAGHPPADFLGW
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHHHHHCCCCCHHHHHH
VLVILGIAIGGGIGAVIAKRVPMTSMPELVAAFHSLVGMAAVLVAAGAFYAPAAFDIGVP
HHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHCCCEEECCCC
GNIHGASLVEMSLGVAIGALTFTGSVIAFLKLSGRMSGAPIILPARHVVNITLGVIMVVA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHH
IIVLVITGHEYAFWVITAVALLLGILMIIPIGGADMPVVISMLNSYSGWAAAGIGFTLGN
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHCCCEEECC
SALIITGALVGSSGAILSYIMCKGMNRSFISVILGGFGGETAAAGGGGGEQRPAKLGSAD
CEEEEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
DAAFIMKNAQKVIIVPGYGMAVAQAQHALREMADTLKKEGVEVKYAIHPVAGRMPGHMNV
CHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEE
LLAEANVPYDEVFELEDINSEFAQADVAFVIGANDVTNPAAEEDPTSPIYGMPVLQVWKA
EEEECCCCHHHHHHHHHCCHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHCC
GTVMFIKRSLASGYAGIDNPLFYRDNTMMLLGDAKKMTENIVKAMNH
CHHHHHHHHHHCCCCCCCCCEEEECCEEEEEECHHHHHHHHHHHHCC
>Mature Secondary Structure
MNANLSALLYLIAGVLFILSLRGLSSPATSRQGNLMGMTGMGIAILTTLAGHPPADFLGW
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHHHHHCCCCCHHHHHH
VLVILGIAIGGGIGAVIAKRVPMTSMPELVAAFHSLVGMAAVLVAAGAFYAPAAFDIGVP
HHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHCCCEEECCCC
GNIHGASLVEMSLGVAIGALTFTGSVIAFLKLSGRMSGAPIILPARHVVNITLGVIMVVA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHH
IIVLVITGHEYAFWVITAVALLLGILMIIPIGGADMPVVISMLNSYSGWAAAGIGFTLGN
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHCCCEEECC
SALIITGALVGSSGAILSYIMCKGMNRSFISVILGGFGGETAAAGGGGGEQRPAKLGSAD
CEEEEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
DAAFIMKNAQKVIIVPGYGMAVAQAQHALREMADTLKKEGVEVKYAIHPVAGRMPGHMNV
CHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEE
LLAEANVPYDEVFELEDINSEFAQADVAFVIGANDVTNPAAEEDPTSPIYGMPVLQVWKA
EEEECCCCHHHHHHHHHCCHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHCC
GTVMFIKRSLASGYAGIDNPLFYRDNTMMLLGDAKKMTENIVKAMNH
CHHHHHHHHHHCCCCCCCCCEEEECCEEEEEECHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]