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The map label for this gene is mcp4 [H]

Identifier: 86748441

GI number: 86748441

Start: 1499620

End: 1501305

Strand: Direct

Name: mcp4 [H]

Synonym: RPB_1316

Alternate gene names: 86748441

Gene position: 1499620-1501305 (Clockwise)

Preceding gene: 86748440

Following gene: 86748442

Centisome position: 28.13

GC content: 66.31

Gene sequence:

>1686_bases
GTGAAGTTCAGCAGCCTTCGTATCACCCCCAAGATCGGAATCCTGGTCGGCGTTGCCTTGCTCGGCCTGTGCGCCGCCGG
GGCCTATGCCGGCATCATGATGCGTCAGGAATTGCTGAACGCCCGAATCGAACAGGCCAAGTCGATCGCCGAGTCGGCGC
GCAGCATGGCGATCGGCCTACAGAAGCAGGTCGATGCCGGCGAACTGACCAAGGACGCCGCGCTCGCCGAATTCACCCGC
CGGGCCAATAGCCTCACCTACGACAACGGCAATGGTTATTTGTTCGCCTACACCAATGACGGAGTGACCCTGGCGTCGCC
GGACAAGAAGGCGCTCGGCACCAACCGCATCAACACGCCGACCGGCGACCGCTTTCTGGTTCGCGAACTGCGCGACGGCG
TGCTGGCCAAGGGCTACGTGCTGCTCAACTATGAATTCCGCAAGCCCGGCTCGGAAGAGTTGATCCGCAAGATGTCCTAC
GGCGTCGCAATTCCCGGCTGGAACGCTTTCGTCGGCACCGGCGCCTATGTGGACGACATCGATGCCACGGTGAAACCGGT
GGTGTGGATGCTCGGAGTCGGCATCCTGGTCATCGGCGCGATCTCGTCGCTGATCGCCTGGCTGATCGGTCGCAGCATCA
CCAAGCCGCTCGGCGAACTCGGCGCGCGGATGAAATCGCTCGCCTCCGGTGAACTCGAGGCGCCGATCCCCGGGATCGCG
CGCGGCGACGAGGTCGGCGAGATGGCGACCACCGTTCAGGTGTTCAAGGACAATGCGCTGCGGATCCGCGGGCTCGAACA
GCAGGAGGCCGAGGTCAAGCAGCGCGCCGCTGCCGAACGCGCCGCGCTGATGCAGCAGATCGCCGACGATTTCGAGCGCA
GCGTCAACGGCGTGGTGCGCAGCGTGGCGGGCGCGACCGCCGAGCTGCAGACGACGGCGCAGTCGATGACCTCGACCGCG
TCGGACGCCAGCTCGCGCGCCGCCGCGGTCGGCTCCGCATCGGATACGGCGTCGAGCATGGTCGGCACCGTCGCGTCGGC
GTCGGAAGAGCTGTCGGCGTCGGTCGCGGAAATTTCCCGCCAGGTGCATCAGTCGCGCGAAATCGCCAGCAAGGCGGTCG
GCGACGCCGAACGCACCAACGAGACCGTCAAGCTGTTGTCGATCGGCGCCGAGAAGATTGGCGAGGTGGTGCAACTGATC
CATTCGATCGCGTCGCAGACCAACCTCTTGGCGCTCAACGCCACCATCGAGGCGGCCCGCGCCGGCGAATCCGGCCGCGG
CTTCGCGGTGGTCGCCTCCGAAGTGAAGGCGCTGGCGAGCCAGACCGCGAAGGCCACCGAGGAAATCTCCTCGCAAGTGT
CGGCGATGCAATCCTCGACCGCGACCGCGGTGGAGTCGATTAACCACATCACCTCGACGATCGGCGAAATGAACAACATC
ACCATGGCGATTTCTTCCGCCGTGGAGCAGCAGGGCTCGGCGACCCGCGAGATCGCCCGCAACATCCAGTCGGTCGCGGC
CGGGTCGAGCGAAATCAGCAGCCACATCGGCGGCGTCAGCGCCGCGGCGTCGGCGACCGGCGATGCCGCCGCGCAGGTGC
TGACGCATGCCCGCGGTCTCGACGGCCAGTCCGGCGCGTTGCAATCCGCCGTCGACGACTTCCTGCACAAGGTCCGTGCG
GCGTAG

Upstream 100 bases:

>100_bases
ACACAAGCTGTGCAAAGTAACACTATTAAAAGCATCTGTTGCTACCGTCCTGCAACCTGAGCCGCGCGCCCGCGCGGTGA
GTTCGGCGTGGAGACGGTCA

Downstream 100 bases:

>100_bases
TCCGCCGGTCCGATCCCTCCGTCGCTCCGAGCCGAATGCCATCGGCCCGGAGCGACGATCACCAGCGATCTTGGCGACCC
GGGGAGAGAGCAACCGGCGC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 561; Mature: 561

Protein sequence:

>561_residues
MKFSSLRITPKIGILVGVALLGLCAAGAYAGIMMRQELLNARIEQAKSIAESARSMAIGLQKQVDAGELTKDAALAEFTR
RANSLTYDNGNGYLFAYTNDGVTLASPDKKALGTNRINTPTGDRFLVRELRDGVLAKGYVLLNYEFRKPGSEELIRKMSY
GVAIPGWNAFVGTGAYVDDIDATVKPVVWMLGVGILVIGAISSLIAWLIGRSITKPLGELGARMKSLASGELEAPIPGIA
RGDEVGEMATTVQVFKDNALRIRGLEQQEAEVKQRAAAERAALMQQIADDFERSVNGVVRSVAGATAELQTTAQSMTSTA
SDASSRAAAVGSASDTASSMVGTVASASEELSASVAEISRQVHQSREIASKAVGDAERTNETVKLLSIGAEKIGEVVQLI
HSIASQTNLLALNATIEAARAGESGRGFAVVASEVKALASQTAKATEEISSQVSAMQSSTATAVESINHITSTIGEMNNI
TMAISSAVEQQGSATREIARNIQSVAAGSSEISSHIGGVSAAASATGDAAAQVLTHARGLDGQSGALQSAVDDFLHKVRA
A

Sequences:

>Translated_561_residues
MKFSSLRITPKIGILVGVALLGLCAAGAYAGIMMRQELLNARIEQAKSIAESARSMAIGLQKQVDAGELTKDAALAEFTR
RANSLTYDNGNGYLFAYTNDGVTLASPDKKALGTNRINTPTGDRFLVRELRDGVLAKGYVLLNYEFRKPGSEELIRKMSY
GVAIPGWNAFVGTGAYVDDIDATVKPVVWMLGVGILVIGAISSLIAWLIGRSITKPLGELGARMKSLASGELEAPIPGIA
RGDEVGEMATTVQVFKDNALRIRGLEQQEAEVKQRAAAERAALMQQIADDFERSVNGVVRSVAGATAELQTTAQSMTSTA
SDASSRAAAVGSASDTASSMVGTVASASEELSASVAEISRQVHQSREIASKAVGDAERTNETVKLLSIGAEKIGEVVQLI
HSIASQTNLLALNATIEAARAGESGRGFAVVASEVKALASQTAKATEEISSQVSAMQSSTATAVESINHITSTIGEMNNI
TMAISSAVEQQGSATREIARNIQSVAAGSSEISSHIGGVSAAASATGDAAAQVLTHARGLDGQSGALQSAVDDFLHKVRA
A
>Mature_561_residues
MKFSSLRITPKIGILVGVALLGLCAAGAYAGIMMRQELLNARIEQAKSIAESARSMAIGLQKQVDAGELTKDAALAEFTR
RANSLTYDNGNGYLFAYTNDGVTLASPDKKALGTNRINTPTGDRFLVRELRDGVLAKGYVLLNYEFRKPGSEELIRKMSY
GVAIPGWNAFVGTGAYVDDIDATVKPVVWMLGVGILVIGAISSLIAWLIGRSITKPLGELGARMKSLASGELEAPIPGIA
RGDEVGEMATTVQVFKDNALRIRGLEQQEAEVKQRAAAERAALMQQIADDFERSVNGVVRSVAGATAELQTTAQSMTSTA
SDASSRAAAVGSASDTASSMVGTVASASEELSASVAEISRQVHQSREIASKAVGDAERTNETVKLLSIGAEKIGEVVQLI
HSIASQTNLLALNATIEAARAGESGRGFAVVASEVKALASQTAKATEEISSQVSAMQSSTATAVESINHITSTIGEMNNI
TMAISSAVEQQGSATREIARNIQSVAAGSSEISSHIGGVSAAASATGDAAAQVLTHARGLDGQSGALQSAVDDFLHKVRA
A

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=600, Percent_Identity=25.5, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI2367378, Length=351, Percent_Identity=29.3447293447293, Blast_Score=102, Evalue=9e-23,
Organism=Escherichia coli, GI1788194, Length=326, Percent_Identity=27.9141104294479, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788195, Length=234, Percent_Identity=33.7606837606838, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1789453, Length=318, Percent_Identity=26.7295597484277, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58342; Mature: 58342

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFSSLRITPKIGILVGVALLGLCAAGAYAGIMMRQELLNARIEQAKSIAESARSMAIGL
CCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKQVDAGELTKDAALAEFTRRANSLTYDNGNGYLFAYTNDGVTLASPDKKALGTNRINTP
HHCCCCHHHHHHHHHHHHHHHHCCCEEECCCEEEEEEECCCEEECCCCCHHCCCCCCCCC
TGDRFLVRELRDGVLAKGYVLLNYEFRKPGSEELIRKMSYGVAIPGWNAFVGTGAYVDDI
CCHHHHHHHHHCCHHCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCHHHCCCCCHHCC
DATVKPVVWMLGVGILVIGAISSLIAWLIGRSITKPLGELGARMKSLASGELEAPIPGIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
RGDEVGEMATTVQVFKDNALRIRGLEQQEAEVKQRAAAERAALMQQIADDFERSVNGVVR
CCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVAGATAELQTTAQSMTSTASDASSRAAAVGSASDTASSMVGTVASASEELSASVAEISR
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVHQSREIASKAVGDAERTNETVKLLSIGAEKIGEVVQLIHSIASQTNLLALNATIEAAR
HHHHHHHHHHHHCCCHHHCCHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEEEECHHHHHH
AGESGRGFAVVASEVKALASQTAKATEEISSQVSAMQSSTATAVESINHITSTIGEMNNI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TMAISSAVEQQGSATREIARNIQSVAAGSSEISSHIGGVSAAASATGDAAAQVLTHARGL
HHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHCCCHHHHHHHHHHHCCC
DGQSGALQSAVDDFLHKVRAA
CCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKFSSLRITPKIGILVGVALLGLCAAGAYAGIMMRQELLNARIEQAKSIAESARSMAIGL
CCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKQVDAGELTKDAALAEFTRRANSLTYDNGNGYLFAYTNDGVTLASPDKKALGTNRINTP
HHCCCCHHHHHHHHHHHHHHHHCCCEEECCCEEEEEEECCCEEECCCCCHHCCCCCCCCC
TGDRFLVRELRDGVLAKGYVLLNYEFRKPGSEELIRKMSYGVAIPGWNAFVGTGAYVDDI
CCHHHHHHHHHCCHHCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCHHHCCCCCHHCC
DATVKPVVWMLGVGILVIGAISSLIAWLIGRSITKPLGELGARMKSLASGELEAPIPGIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
RGDEVGEMATTVQVFKDNALRIRGLEQQEAEVKQRAAAERAALMQQIADDFERSVNGVVR
CCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVAGATAELQTTAQSMTSTASDASSRAAAVGSASDTASSMVGTVASASEELSASVAEISR
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVHQSREIASKAVGDAERTNETVKLLSIGAEKIGEVVQLIHSIASQTNLLALNATIEAAR
HHHHHHHHHHHHCCCHHHCCHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEEEECHHHHHH
AGESGRGFAVVASEVKALASQTAKATEEISSQVSAMQSSTATAVESINHITSTIGEMNNI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TMAISSAVEQQGSATREIARNIQSVAAGSSEISSHIGGVSAAASATGDAAAQVLTHARGL
HHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHCCCHHHHHHHHHHHCCC
DGQSGALQSAVDDFLHKVRAA
CCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]