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The map label for this gene is mcp4 [H]

Identifier: 86748442

GI number: 86748442

Start: 1501512

End: 1503194

Strand: Direct

Name: mcp4 [H]

Synonym: RPB_1317

Alternate gene names: 86748442

Gene position: 1501512-1503194 (Clockwise)

Preceding gene: 86748441

Following gene: 86748443

Centisome position: 28.16

GC content: 66.73

Gene sequence:

>1683_bases
GTGCACTTCAGCAATCTTCGCATCACGCCGAAATTGAGCATTCTCGTCGCTGTGGCGATGCTCGGCCTGATTGCCGCCGG
TGTGTTCGCCGCATCCATTCTGCATCGCGAGATGCGTGCCGGTCGCTTCGAGCAGACCAAGGCGATGGTCGAGACCGCGC
TGAACATGGCGATCGGGCTGCAGAAGCAGGTCGATGCCGGCAAGCTGACCAAGGATCAGGCGATCTCCGACTTCCAGCAG
CGCGCCCAGGCGATGACCTATGACGGCGCCAACGGCTATTTCTTCGCCTACAAGATGGACGGAGAGGTCGTGCTGCTGCC
GGGGGTGAAGCCCGGCACGAACCGGCTCGACGTCGAGACGGCCGGCCGCAAGATCGTCCGCGAATTGCGTGATGGCGTCG
CCGCCAAGGGCAACGTCACGCTGTTCTACGAATTCAAGAAGCCGGGCGGCGACGAACTGCTCAGCAAGGTATCGTATGCG
GCCGCGATCCCCGGCTGGAACGTCTTCGTCGGCACCGGCGTCTATCTGCAGGACATCGACGCCAAGCTGAAGCCGATCAT
GATGTGGCTCGGGCTCGCCATTCTCGGCATCGGCGCCGTCTGCTCGCTGGTCGCCTGGCTGATCAGCCGCAGCATCACCA
AGCCGCTCGGCCGTCTCGGTGCACGGATGAAGTCGCTCGCCGGCGGCCAGATCGATGCGCCGATCCCGGGTGTCGACCGC
GGCGACGAGGTCGGCGAGATGGCGAAGACGGTGCAGGTGTTCCAGGACAATGCCATCCGCATCCGCGGCCTCGAGCAGCA
GGAGCAGGAAGCGCAGCAGCGCGCGGGCGCCGAGCGGCGGGCGCTGATGGAGAACATCGCCGACGATTTCGAGCGCAGCG
TCAACGGCGTGGTGCGCAGCGTGGCCGATGCGACCAAGGAAATGCAGGCGACCGCACAATCGATGACCGCGACCGCCTCG
GATGCGAGTTTGCGCGCCGGGGCTGTCGGTGCCGCGTCGGAAGCGTCCGCCGGGATGGTCGGCACCGTCGCCTCGGCGTC
CGAACAACTATCCGCGTCGGTCCATGAGATTTCCCGGCAGGTGCAGCAGTCGCGCGAGATCGCCGGCAAGGCCGTCAGCG
ACGCCGAGCACACCAACGAGACGGTGATGCAGCTCTCGGTCAGCGCCGAGAAGATCGGCGAAGTGGTGCAACTGATCCAT
TCGATCGCGTCGCAGACCAACCTGCTGGCGCTGAACGCCACCATCGAGGCGGCGCGCGCCGGCGAATCCGGCCGCGGCTT
CGCGGTGGTCGCCTCCGAAGTGAAGGCGCTGGCGGGCCAGACCGCGAAGGCGACCGAGGAGATTTCGGCGCAGGTGTCGG
CGATGCAGGCGTCGACCGCGAACGCGGTGGATTCGATCAGTGGAATCACCTCCACCATCGGGCAGATGAGCGAGATCACC
ATGGCGATCTCCAGCGCCGTCGAGCAGCAGGGCGCGGCGACGCGCGACATCGCCCGCAATATCCAGTCGGTTGCGGCCGG
GTCGAGCGAGATCAGCGGCCATATCAGCGGCGTCAGCGACGCGGCGGCCGCGACCGGCGAAGCCGCGGCGCAGGTGCTCG
CGCATGCGGGCGAACTGGACGGCCAGTCCGATGCGCTGCAATCGGCGGTCGATGACTTCCTGCAGAAGGTCCGCGCCGCC
TGA

Upstream 100 bases:

>100_bases
CCTCGTGCTTCTACGGGGAGGCATTTAAACGGGTTGGATACCCGATGCCGCTACGCGTTGATGGCTGCGCGATCACCGCG
CCGGCTTCGGAGTCGTCCCC

Downstream 100 bases:

>100_bases
CGCGACGGCGCGAGGCGCCGCCGTCACGGTCGGCCCCTTCCAACGATGCGAGAACGCGCACTGCAGCGACGGCGCGCATT
CTGATCGGCCGGGCGGCGCA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 560; Mature: 560

Protein sequence:

>560_residues
MHFSNLRITPKLSILVAVAMLGLIAAGVFAASILHREMRAGRFEQTKAMVETALNMAIGLQKQVDAGKLTKDQAISDFQQ
RAQAMTYDGANGYFFAYKMDGEVVLLPGVKPGTNRLDVETAGRKIVRELRDGVAAKGNVTLFYEFKKPGGDELLSKVSYA
AAIPGWNVFVGTGVYLQDIDAKLKPIMMWLGLAILGIGAVCSLVAWLISRSITKPLGRLGARMKSLAGGQIDAPIPGVDR
GDEVGEMAKTVQVFQDNAIRIRGLEQQEQEAQQRAGAERRALMENIADDFERSVNGVVRSVADATKEMQATAQSMTATAS
DASLRAGAVGAASEASAGMVGTVASASEQLSASVHEISRQVQQSREIAGKAVSDAEHTNETVMQLSVSAEKIGEVVQLIH
SIASQTNLLALNATIEAARAGESGRGFAVVASEVKALAGQTAKATEEISAQVSAMQASTANAVDSISGITSTIGQMSEIT
MAISSAVEQQGAATRDIARNIQSVAAGSSEISGHISGVSDAAAATGEAAAQVLAHAGELDGQSDALQSAVDDFLQKVRAA

Sequences:

>Translated_560_residues
MHFSNLRITPKLSILVAVAMLGLIAAGVFAASILHREMRAGRFEQTKAMVETALNMAIGLQKQVDAGKLTKDQAISDFQQ
RAQAMTYDGANGYFFAYKMDGEVVLLPGVKPGTNRLDVETAGRKIVRELRDGVAAKGNVTLFYEFKKPGGDELLSKVSYA
AAIPGWNVFVGTGVYLQDIDAKLKPIMMWLGLAILGIGAVCSLVAWLISRSITKPLGRLGARMKSLAGGQIDAPIPGVDR
GDEVGEMAKTVQVFQDNAIRIRGLEQQEQEAQQRAGAERRALMENIADDFERSVNGVVRSVADATKEMQATAQSMTATAS
DASLRAGAVGAASEASAGMVGTVASASEQLSASVHEISRQVQQSREIAGKAVSDAEHTNETVMQLSVSAEKIGEVVQLIH
SIASQTNLLALNATIEAARAGESGRGFAVVASEVKALAGQTAKATEEISAQVSAMQASTANAVDSISGITSTIGQMSEIT
MAISSAVEQQGAATRDIARNIQSVAAGSSEISGHISGVSDAAAATGEAAAQVLAHAGELDGQSDALQSAVDDFLQKVRAA
>Mature_560_residues
MHFSNLRITPKLSILVAVAMLGLIAAGVFAASILHREMRAGRFEQTKAMVETALNMAIGLQKQVDAGKLTKDQAISDFQQ
RAQAMTYDGANGYFFAYKMDGEVVLLPGVKPGTNRLDVETAGRKIVRELRDGVAAKGNVTLFYEFKKPGGDELLSKVSYA
AAIPGWNVFVGTGVYLQDIDAKLKPIMMWLGLAILGIGAVCSLVAWLISRSITKPLGRLGARMKSLAGGQIDAPIPGVDR
GDEVGEMAKTVQVFQDNAIRIRGLEQQEQEAQQRAGAERRALMENIADDFERSVNGVVRSVADATKEMQATAQSMTATAS
DASLRAGAVGAASEASAGMVGTVASASEQLSASVHEISRQVQQSREIAGKAVSDAEHTNETVMQLSVSAEKIGEVVQLIH
SIASQTNLLALNATIEAARAGESGRGFAVVASEVKALAGQTAKATEEISAQVSAMQASTANAVDSISGITSTIGQMSEIT
MAISSAVEQQGAATRDIARNIQSVAAGSSEISGHISGVSDAAAATGEAAAQVLAHAGELDGQSDALQSAVDDFLQKVRAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=340, Percent_Identity=28.8235294117647, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI2367378, Length=336, Percent_Identity=28.2738095238095, Blast_Score=102, Evalue=9e-23,
Organism=Escherichia coli, GI1788195, Length=318, Percent_Identity=28.9308176100629, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1787690, Length=383, Percent_Identity=28.7206266318538, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1789453, Length=364, Percent_Identity=26.3736263736264, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58475; Mature: 58475

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFSNLRITPKLSILVAVAMLGLIAAGVFAASILHREMRAGRFEQTKAMVETALNMAIGL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
QKQVDAGKLTKDQAISDFQQRAQAMTYDGANGYFFAYKMDGEVVLLPGVKPGTNRLDVET
HHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEEECCCCCCCCCCCHHH
AGRKIVRELRDGVAAKGNVTLFYEFKKPGGDELLSKVSYAAAIPGWNVFVGTGVYLQDID
HHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHHH
AKLKPIMMWLGLAILGIGAVCSLVAWLISRSITKPLGRLGARMKSLAGGQIDAPIPGVDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GDEVGEMAKTVQVFQDNAIRIRGLEQQEQEAQQRAGAERRALMENIADDFERSVNGVVRS
CHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
VADATKEMQATAQSMTATASDASLRAGAVGAASEASAGMVGTVASASEQLSASVHEISRQ
HHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VQQSREIAGKAVSDAEHTNETVMQLSVSAEKIGEVVQLIHSIASQTNLLALNATIEAARA
HHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHC
GESGRGFAVVASEVKALAGQTAKATEEISAQVSAMQASTANAVDSISGITSTIGQMSEIT
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MAISSAVEQQGAATRDIARNIQSVAAGSSEISGHISGVSDAAAATGEAAAQVLAHAGELD
HHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
GQSDALQSAVDDFLQKVRAA
CHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHFSNLRITPKLSILVAVAMLGLIAAGVFAASILHREMRAGRFEQTKAMVETALNMAIGL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
QKQVDAGKLTKDQAISDFQQRAQAMTYDGANGYFFAYKMDGEVVLLPGVKPGTNRLDVET
HHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEEECCCCCCCCCCCHHH
AGRKIVRELRDGVAAKGNVTLFYEFKKPGGDELLSKVSYAAAIPGWNVFVGTGVYLQDID
HHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHHH
AKLKPIMMWLGLAILGIGAVCSLVAWLISRSITKPLGRLGARMKSLAGGQIDAPIPGVDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GDEVGEMAKTVQVFQDNAIRIRGLEQQEQEAQQRAGAERRALMENIADDFERSVNGVVRS
CHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
VADATKEMQATAQSMTATASDASLRAGAVGAASEASAGMVGTVASASEQLSASVHEISRQ
HHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VQQSREIAGKAVSDAEHTNETVMQLSVSAEKIGEVVQLIHSIASQTNLLALNATIEAARA
HHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHC
GESGRGFAVVASEVKALAGQTAKATEEISAQVSAMQASTANAVDSISGITSTIGQMSEIT
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MAISSAVEQQGAATRDIARNIQSVAAGSSEISGHISGVSDAAAATGEAAAQVLAHAGELD
HHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
GQSDALQSAVDDFLQKVRAA
CHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]