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The map label for this gene is aatA [H]

Identifier: 86748422

GI number: 86748422

Start: 1479172

End: 1480374

Strand: Direct

Name: aatA [H]

Synonym: RPB_1297

Alternate gene names: 86748422

Gene position: 1479172-1480374 (Clockwise)

Preceding gene: 86748418

Following gene: 86748423

Centisome position: 27.74

GC content: 64.59

Gene sequence:

>1203_bases
ATGTCGTTCCTGTCCACCGCGCTCGATCGTGTGAAGCCGTCCGCGACCATCGCGGTCACGGACAAGGCACGTGAGCTGAA
AGCGGCGGGCCGCAACGTCATCGGGCTCGGCTCCGGCGAGCCGGATTTCGACACGCCCGCCAACATCAAGCTGGCGGCGA
TCCACGCCATCGAGGCCGGCAAGACCAAGTACACCGCGGTCGACGGCATTCCGGAGCTGAAGCAGGCGATCATCGACAAG
TTTCAGCGCGAGAACGGCCTGACCTACAAGCCCAACCAGATCATCGTCGGCACCGGCGGCAAGCAGGTGCTGTACAACGC
GCTGATCGCCACCATCAATCCCGGCGACGAGGTGATCATCCCGGCGCCGTATTGGGTCAGCTATCCGGAAATGGTGGCGC
TCGCCGGCGGCGAGTCGGTGCCGGTGGTGTGCCCGGCGGAATCCGGCTTCAAGCTGCAGCCGGCGGCGCTGGAGGCAGCG
ATTACGCCGAAGACCAAGTGGATCATTCTCAATTCGCCGTCGAACCCGACCGGCGCCGCCTATTCGCGCGAAGAGTTGAA
GGCGCTCACCGACGTGCTGGTCAAGCATCCGCACGTCTGGGTGATGACCGACGACATGTACGAGCATCTCGTCTACGACG
ATTTCGACTTCACCACCCCGGCGCAGATCGAGCCGCGTCTGTTCGATCGCACGCTGACCGTGAACGGCGTGTCGAAATCC
TATTGTATGACCGGCTGGCGGATCGGCTATGCGGGCGGCCCGGCGCAATTGATCAAGGCGATGGCGACGATCCAGTCGCA
GTCGACCTCGAACCCGTCCTCGATCGCCCAATGGGCGGCGGTGGAAGCGCTCAACGGCCCGCAGGACTTCATCGCCGCCC
ACAACAAGGTGTTCAAGGAGCGCCGCGACCTCGTGGTGTCGATGCTGAACCAGGCGTCGGGGATCGATTGCCCGCGGCCG
GAAGGGGCGTTCTACGTCTATCCGTCCTGCGCCGGCACGATCGGCAAGACCGCGCCGTCCGGCAAGGTCATCGAGACCGA
TCAGGACTTCGTCACCGAGCTGCTCGAAGCCGAGGGCGTCGCGGTGGTGCAGGGCTCGGCGTTCGGCCTCGGCCCGGCGT
TCCGGATTTCCTACGCGACGAAAACCTCGGATCTCGAAGAAGCCTGCAAGCGCATCCAGCGCTTTTGCGGGAACCTGCGC
TGA

Upstream 100 bases:

>100_bases
TCTTGCGATGCAGCGTGCCGGCGCTTAGTGTGGGGCATCCCCGTCAGAAATCGAAGAGTCGCGCCCTCCGCCGGCTCATG
ACGGCTGCAAGGAGAAGACG

Downstream 100 bases:

>100_bases
AGGTTCAACCGGCCGTTCATTAAAGATCGGCAAGGTTGGTTAGATTTATTCCGGCATCGTGGAAGCGCCTTGTTTTGGAC
AAGACGCTTCCTTCTTGTCG

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MSFLSTALDRVKPSATIAVTDKARELKAAGRNVIGLGSGEPDFDTPANIKLAAIHAIEAGKTKYTAVDGIPELKQAIIDK
FQRENGLTYKPNQIIVGTGGKQVLYNALIATINPGDEVIIPAPYWVSYPEMVALAGGESVPVVCPAESGFKLQPAALEAA
ITPKTKWIILNSPSNPTGAAYSREELKALTDVLVKHPHVWVMTDDMYEHLVYDDFDFTTPAQIEPRLFDRTLTVNGVSKS
YCMTGWRIGYAGGPAQLIKAMATIQSQSTSNPSSIAQWAAVEALNGPQDFIAAHNKVFKERRDLVVSMLNQASGIDCPRP
EGAFYVYPSCAGTIGKTAPSGKVIETDQDFVTELLEAEGVAVVQGSAFGLGPAFRISYATKTSDLEEACKRIQRFCGNLR

Sequences:

>Translated_400_residues
MSFLSTALDRVKPSATIAVTDKARELKAAGRNVIGLGSGEPDFDTPANIKLAAIHAIEAGKTKYTAVDGIPELKQAIIDK
FQRENGLTYKPNQIIVGTGGKQVLYNALIATINPGDEVIIPAPYWVSYPEMVALAGGESVPVVCPAESGFKLQPAALEAA
ITPKTKWIILNSPSNPTGAAYSREELKALTDVLVKHPHVWVMTDDMYEHLVYDDFDFTTPAQIEPRLFDRTLTVNGVSKS
YCMTGWRIGYAGGPAQLIKAMATIQSQSTSNPSSIAQWAAVEALNGPQDFIAAHNKVFKERRDLVVSMLNQASGIDCPRP
EGAFYVYPSCAGTIGKTAPSGKVIETDQDFVTELLEAEGVAVVQGSAFGLGPAFRISYATKTSDLEEACKRIQRFCGNLR
>Mature_399_residues
SFLSTALDRVKPSATIAVTDKARELKAAGRNVIGLGSGEPDFDTPANIKLAAIHAIEAGKTKYTAVDGIPELKQAIIDKF
QRENGLTYKPNQIIVGTGGKQVLYNALIATINPGDEVIIPAPYWVSYPEMVALAGGESVPVVCPAESGFKLQPAALEAAI
TPKTKWIILNSPSNPTGAAYSREELKALTDVLVKHPHVWVMTDDMYEHLVYDDFDFTTPAQIEPRLFDRTLTVNGVSKSY
CMTGWRIGYAGGPAQLIKAMATIQSQSTSNPSSIAQWAAVEALNGPQDFIAAHNKVFKERRDLVVSMLNQASGIDCPRPE
GAFYVYPSCAGTIGKTAPSGKVIETDQDFVTELLEAEGVAVVQGSAFGLGPAFRISYATKTSDLEEACKRIQRFCGNLR

Specific function: Required for symbiotic nitrogen fixation [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=390, Percent_Identity=28.4615384615385, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI56713256, Length=390, Percent_Identity=28.4615384615385, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI95147551, Length=364, Percent_Identity=28.5714285714286, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI169881279, Length=364, Percent_Identity=28.5714285714286, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI169881281, Length=271, Percent_Identity=27.6752767527675, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI4507369, Length=396, Percent_Identity=23.4848484848485, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI1788627, Length=405, Percent_Identity=28.8888888888889, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1786816, Length=378, Percent_Identity=28.3068783068783, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1788722, Length=372, Percent_Identity=30.6451612903226, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1787710, Length=225, Percent_Identity=29.3333333333333, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71994472, Length=364, Percent_Identity=29.1208791208791, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI71994476, Length=364, Percent_Identity=29.1208791208791, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17567369, Length=402, Percent_Identity=26.3681592039801, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17567663, Length=378, Percent_Identity=24.3386243386243, Blast_Score=115, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6322401, Length=311, Percent_Identity=29.2604501607717, Blast_Score=126, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6320317, Length=366, Percent_Identity=25.9562841530055, Blast_Score=96, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6323118, Length=365, Percent_Identity=23.2876712328767, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28573069, Length=399, Percent_Identity=27.3182957393484, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24646114, Length=399, Percent_Identity=27.3182957393484, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI28573067, Length=399, Percent_Identity=27.3182957393484, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI28573065, Length=399, Percent_Identity=27.3182957393484, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI18859735, Length=358, Percent_Identity=24.8603351955307, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI45551451, Length=398, Percent_Identity=25.1256281407035, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641770, Length=398, Percent_Identity=25.1256281407035, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641760, Length=398, Percent_Identity=25.1256281407035, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641768, Length=398, Percent_Identity=25.1256281407035, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641766, Length=398, Percent_Identity=25.1256281407035, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641764, Length=398, Percent_Identity=25.1256281407035, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43102; Mature: 42970

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFLSTALDRVKPSATIAVTDKARELKAAGRNVIGLGSGEPDFDTPANIKLAAIHAIEAG
CCHHHHHHHHCCCCEEEEECCHHHHHHHCCCCEEECCCCCCCCCCCCCEEEEEEEEEECC
KTKYTAVDGIPELKQAIIDKFQRENGLTYKPNQIIVGTGGKQVLYNALIATINPGDEVII
CCEEEEECCCHHHHHHHHHHHHHCCCCEECCCEEEEECCCHHHHHHHHHEEECCCCCEEE
PAPYWVSYPEMVALAGGESVPVVCPAESGFKLQPAALEAAITPKTKWIILNSPSNPTGAA
CCCCCCCCCHHEEECCCCCCCEEECCCCCCEECHHHHHEEECCCEEEEEEECCCCCCCCC
YSREELKALTDVLVKHPHVWVMTDDMYEHLVYDDFDFTTPAQIEPRLFDRTLTVNGVSKS
CCHHHHHHHHHHHHCCCEEEEEECHHHHHHHCCCCCCCCCCCCCHHHCCEEEEECCCCCC
YCMTGWRIGYAGGPAQLIKAMATIQSQSTSNPSSIAQWAAVEALNGPQDFIAAHNKVFKE
HHHCCEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
RRDLVVSMLNQASGIDCPRPEGAFYVYPSCAGTIGKTAPSGKVIETDQDFVTELLEAEGV
HHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCCEEECCHHHHHHHHHCCCE
AVVQGSAFGLGPAFRISYATKTSDLEEACKRIQRFCGNLR
EEEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SFLSTALDRVKPSATIAVTDKARELKAAGRNVIGLGSGEPDFDTPANIKLAAIHAIEAG
CHHHHHHHHCCCCEEEEECCHHHHHHHCCCCEEECCCCCCCCCCCCCEEEEEEEEEECC
KTKYTAVDGIPELKQAIIDKFQRENGLTYKPNQIIVGTGGKQVLYNALIATINPGDEVII
CCEEEEECCCHHHHHHHHHHHHHCCCCEECCCEEEEECCCHHHHHHHHHEEECCCCCEEE
PAPYWVSYPEMVALAGGESVPVVCPAESGFKLQPAALEAAITPKTKWIILNSPSNPTGAA
CCCCCCCCCHHEEECCCCCCCEEECCCCCCEECHHHHHEEECCCEEEEEEECCCCCCCCC
YSREELKALTDVLVKHPHVWVMTDDMYEHLVYDDFDFTTPAQIEPRLFDRTLTVNGVSKS
CCHHHHHHHHHHHHCCCEEEEEECHHHHHHHCCCCCCCCCCCCCHHHCCEEEEECCCCCC
YCMTGWRIGYAGGPAQLIKAMATIQSQSTSNPSSIAQWAAVEALNGPQDFIAAHNKVFKE
HHHCCEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
RRDLVVSMLNQASGIDCPRPEGAFYVYPSCAGTIGKTAPSGKVIETDQDFVTELLEAEGV
HHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCCEEECCHHHHHHHHHCCCE
AVVQGSAFGLGPAFRISYATKTSDLEEACKRIQRFCGNLR
EEEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2019560; 8096210; 11481430 [H]