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The map label for this gene is siaT [H]

Identifier: 86748418

GI number: 86748418

Start: 1475132

End: 1476454

Strand: Direct

Name: siaT [H]

Synonym: RPB_1293

Alternate gene names: 86748418

Gene position: 1475132-1476454 (Clockwise)

Preceding gene: 86748417

Following gene: 86748422

Centisome position: 27.67

GC content: 65.31

Gene sequence:

>1323_bases
GTGTCTGTCGAACTCCTGACCCTGCTGTTCTTCGGTTCGCTGCTGTTCTTCCTGTTCATCGGCACGCCGCTGGCGTTCAC
GCTCGGCGGCATTTCCGTGGTGTTTCTGTATTTCACCATGGGGCCGGTCGGCTTCTACATCGTCGCGTCGAAATTCTGGG
ACTCGATGACCAGCTTCACGCTGATCGCGATCCCGATGTACGTGTACATGGCGATGTTGCTCGAGAAATCGGGCGTGGCG
CAGGACCTGTACCGGATGATGCACGTCTGGTTCGGCGCGATGCGCGGCGGGCTGGCGATCGGCACGGTGCTGATCTGCGC
GATCTTCGCGGCGATGAGCGGCATCAGCGGCGCCGCCGTGGTCACCATGGGCGCCATCGCGTTGCCGCGGATGCTCGAGC
GCGGTTACGACAAGCGGCTCGCGCTCGGCGCGATCAATGCCGGCGGCGGCTGGGGCGTGCTGATCCCGCCGTCGATCCTG
ATGGTGCTCTACGCGCTGCTGACCGAAGTGTCGGTCGGCCGCCTGTTCGCCTCCGGCATCGGTCCCGGCATTCTGCTCGT
CGTGCTGGTGACGATCTACATCACCGTCCGCGCCTGGCTGCAGCCGTCGCTGGCGCCGGCGCTGCCGGTCGAGGAGCGCG
GCGACTGGGGGCTGAAATTCGCGTCGCTGAAGGCCGTCGTGCTGCCGCTGCTGATCGTGGTGATGGTGCTCGGCGCGATC
TTCGGCGGCTTCGCGACGCCGACCGAAGCCGCGGCGCTCGGCGTGTTCGGCGCGCTGGTCGCCTCCGCGGTGCATCGCAA
GCTGACGCTGGAGGTGCTGACCGACGCCGCGATGCAGACGCTGCGCCTCACCGCGCTGATCATGTGGATCCTGTTCGCCG
CGCACGCGTTCTCGACGGCCTACACCACGCTCGGCGCCAACGAACTGATGAACCATCTGATGACGCTGATTCCCGGCGGC
GAGTGGGGCGCGCTGGCCTTCATCCTGCTCGTGCTGCTGCTGCTCGGCATGGTGCTGGATCCGGTCGGCATCATGCTGAT
CACGCTCCCGGTGTTCATCCCCGTGGTGCAGCTCTACGGCTGGGACCCGGTCTGGTTCGGCGTCGTCTTCATCATCATGA
TGGAGATCGGCTACATGACGCCGCCGTTCGGCTTCAACCTGTTCTACCTCAAGGCGGTGGCGCCGCCCGAGGTCAGCATG
AGCGACATCTACTGGTCGGTCGTGCCGTATGTGCTGGTGACGCTGCTGGGCGTGCTGATCCTGATCATCTTCCCGCAGAT
CGCGCTGTTCTTCCCGAATCTGTTCTTCGGCGTTGCACGCTAG

Upstream 100 bases:

>100_bases
TGTCGCCTCCGACATCCGCACCGTGGCCGGATACGAGAACGACCCCGAAACGTTCGGCAAGCAGGCCGGCGACGATCCCT
CTCACTGAACGGACGGTCTC

Downstream 100 bases:

>100_bases
CGCCGGGGCCGCCGGCTCAGTCCGCGGCCGGCGTCACGCGCAGGATGCGTCCGGCGGCGTTGTCGGTCAGCAGCCACAGC
GCGCCGTCGGGGCCCTGGCG

Product: TRAP dicarboxylate transporter DctM subunit

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MSVELLTLLFFGSLLFFLFIGTPLAFTLGGISVVFLYFTMGPVGFYIVASKFWDSMTSFTLIAIPMYVYMAMLLEKSGVA
QDLYRMMHVWFGAMRGGLAIGTVLICAIFAAMSGISGAAVVTMGAIALPRMLERGYDKRLALGAINAGGGWGVLIPPSIL
MVLYALLTEVSVGRLFASGIGPGILLVVLVTIYITVRAWLQPSLAPALPVEERGDWGLKFASLKAVVLPLLIVVMVLGAI
FGGFATPTEAAALGVFGALVASAVHRKLTLEVLTDAAMQTLRLTALIMWILFAAHAFSTAYTTLGANELMNHLMTLIPGG
EWGALAFILLVLLLLGMVLDPVGIMLITLPVFIPVVQLYGWDPVWFGVVFIIMMEIGYMTPPFGFNLFYLKAVAPPEVSM
SDIYWSVVPYVLVTLLGVLILIIFPQIALFFPNLFFGVAR

Sequences:

>Translated_440_residues
MSVELLTLLFFGSLLFFLFIGTPLAFTLGGISVVFLYFTMGPVGFYIVASKFWDSMTSFTLIAIPMYVYMAMLLEKSGVA
QDLYRMMHVWFGAMRGGLAIGTVLICAIFAAMSGISGAAVVTMGAIALPRMLERGYDKRLALGAINAGGGWGVLIPPSIL
MVLYALLTEVSVGRLFASGIGPGILLVVLVTIYITVRAWLQPSLAPALPVEERGDWGLKFASLKAVVLPLLIVVMVLGAI
FGGFATPTEAAALGVFGALVASAVHRKLTLEVLTDAAMQTLRLTALIMWILFAAHAFSTAYTTLGANELMNHLMTLIPGG
EWGALAFILLVLLLLGMVLDPVGIMLITLPVFIPVVQLYGWDPVWFGVVFIIMMEIGYMTPPFGFNLFYLKAVAPPEVSM
SDIYWSVVPYVLVTLLGVLILIIFPQIALFFPNLFFGVAR
>Mature_439_residues
SVELLTLLFFGSLLFFLFIGTPLAFTLGGISVVFLYFTMGPVGFYIVASKFWDSMTSFTLIAIPMYVYMAMLLEKSGVAQ
DLYRMMHVWFGAMRGGLAIGTVLICAIFAAMSGISGAAVVTMGAIALPRMLERGYDKRLALGAINAGGGWGVLIPPSILM
VLYALLTEVSVGRLFASGIGPGILLVVLVTIYITVRAWLQPSLAPALPVEERGDWGLKFASLKAVVLPLLIVVMVLGAIF
GGFATPTEAAALGVFGALVASAVHRKLTLEVLTDAAMQTLRLTALIMWILFAAHAFSTAYTTLGANELMNHLMTLIPGGE
WGALAFILLVLLLLGMVLDPVGIMLITLPVFIPVVQLYGWDPVWFGVVFIIMMEIGYMTPPFGFNLFYLKAVAPPEVSMS
DIYWSVVPYVLVTLLGVLILIIFPQIALFFPNLFFGVAR

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG4664

COG function: function code Q; TRAP-type mannitol/chloroaromatic compound transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=405, Percent_Identity=29.6296296296296, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 47548; Mature: 47417

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVELLTLLFFGSLLFFLFIGTPLAFTLGGISVVFLYFTMGPVGFYIVASKFWDSMTSFT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIAIPMYVYMAMLLEKSGVAQDLYRMMHVWFGAMRGGLAIGTVLICAIFAAMSGISGAAV
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHH
VTMGAIALPRMLERGYDKRLALGAINAGGGWGVLIPPSILMVLYALLTEVSVGRLFASGI
HHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHCC
GPGILLVVLVTIYITVRAWLQPSLAPALPVEERGDWGLKFASLKAVVLPLLIVVMVLGAI
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FGGFATPTEAAALGVFGALVASAVHRKLTLEVLTDAAMQTLRLTALIMWILFAAHAFSTA
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YTTLGANELMNHLMTLIPGGEWGALAFILLVLLLLGMVLDPVGIMLITLPVFIPVVQLYG
HHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
WDPVWFGVVFIIMMEIGYMTPPFGFNLFYLKAVAPPEVSMSDIYWSVVPYVLVTLLGVLI
CCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
LIIFPQIALFFPNLFFGVAR
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVELLTLLFFGSLLFFLFIGTPLAFTLGGISVVFLYFTMGPVGFYIVASKFWDSMTSFT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIAIPMYVYMAMLLEKSGVAQDLYRMMHVWFGAMRGGLAIGTVLICAIFAAMSGISGAAV
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHH
VTMGAIALPRMLERGYDKRLALGAINAGGGWGVLIPPSILMVLYALLTEVSVGRLFASGI
HHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHCC
GPGILLVVLVTIYITVRAWLQPSLAPALPVEERGDWGLKFASLKAVVLPLLIVVMVLGAI
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FGGFATPTEAAALGVFGALVASAVHRKLTLEVLTDAAMQTLRLTALIMWILFAAHAFSTA
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YTTLGANELMNHLMTLIPGGEWGALAFILLVLLLLGMVLDPVGIMLITLPVFIPVVQLYG
HHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
WDPVWFGVVFIIMMEIGYMTPPFGFNLFYLKAVAPPEVSMSDIYWSVVPYVLVTLLGVLI
CCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
LIIFPQIALFFPNLFFGVAR
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]