Click here to switch to the map view.

The map label for this gene is trpG [H]

Identifier: 86609852

GI number: 86609852

Start: 2514222

End: 2514875

Strand: Direct

Name: trpG [H]

Synonym: CYB_2417

Alternate gene names: 86609852

Gene position: 2514222-2514875 (Clockwise)

Preceding gene: 86609849

Following gene: 86609853

Centisome position: 82.52

GC content: 58.41

Gene sequence:

>654_bases
GTGCTGGTCGTCATCGACAACTACGACAGCTTTACCTACAACTTGGTGCAGTACCTGGGGGAGTTGGGAGCTCAGCTTCA
GGTTTTTCGCAATGACCAGCTCTCCGTTGACGACCTGCGCCGAATGCAGCCGCAAGCTGTAGTTATCTCTCCTGGGCCAG
GGCGGCCAGAAGATGCTGGGATCTCGCTGGAGTTGATTCGGGAGCTGGGGCCAGAGCTGCCGATTTTGGGGGTTTGTCTG
GGGCACCAGTGCATTGGCCAGGTCTATGGTGGTCAGATCGTGCGCGCACCTGAGCTGATGCATGGCAAAACCTCGCTCAT
TTACCATCGAGGGGTGGGGGTGTTTGAGGGGTTGAGCCAGCCTTTCACGGCCACCCGCTACCACAGCTTGGTGATCGAGC
CTTCTACGTGTCCTGACGAGCTGGAGGTGACGGCTCAAACAGGCGATGGGATCATCATGGGGGTACGCCACCGCCGCTAT
CCCCACGTTCAGGGCGTGCAGTTCCACCCGGAGAGCATCTTGACTGCAGAGGGCAAGCGCTTGTTGAGCAACTTCCTGCG
CAGCGCCAAAGCCTCAACTGCTGCTCAGCCCAATGTTTCGCAGAAACCTCAGGAAACCGTTGCCGTTGTTACATCAGGGA
TCCCCACTCCATGA

Upstream 100 bases:

>100_bases
GACTGCTCCCCTGCAAAAAGCGCCAGTTACTCTGCTTCTTTGGATCAAGAACAGCAGCTCAAGCAAGTGCTAAAATGGGG
TGCCGTTGCCGGATGCTATC

Downstream 100 bases:

>100_bases
AGCGTCGCCAGCTTCTGCAAGCCAGCGCTGGGCTACTGGGATCGATGGCCGTGAACCTGGCCAGAGGGCGCAAAGCGGGC
GCTCAGACAGCGCCGGCACA

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amidotransferase; Anthranilate phosphoribosyltransferase [H]

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MLVVIDNYDSFTYNLVQYLGELGAQLQVFRNDQLSVDDLRRMQPQAVVISPGPGRPEDAGISLELIRELGPELPILGVCL
GHQCIGQVYGGQIVRAPELMHGKTSLIYHRGVGVFEGLSQPFTATRYHSLVIEPSTCPDELEVTAQTGDGIIMGVRHRRY
PHVQGVQFHPESILTAEGKRLLSNFLRSAKASTAAQPNVSQKPQETVAVVTSGIPTP

Sequences:

>Translated_217_residues
MLVVIDNYDSFTYNLVQYLGELGAQLQVFRNDQLSVDDLRRMQPQAVVISPGPGRPEDAGISLELIRELGPELPILGVCL
GHQCIGQVYGGQIVRAPELMHGKTSLIYHRGVGVFEGLSQPFTATRYHSLVIEPSTCPDELEVTAQTGDGIIMGVRHRRY
PHVQGVQFHPESILTAEGKRLLSNFLRSAKASTAAQPNVSQKPQETVAVVTSGIPTP
>Mature_217_residues
MLVVIDNYDSFTYNLVQYLGELGAQLQVFRNDQLSVDDLRRMQPQAVVISPGPGRPEDAGISLELIRELGPELPILGVCL
GHQCIGQVYGGQIVRAPELMHGKTSLIYHRGVGVFEGLSQPFTATRYHSLVIEPSTCPDELEVTAQTGDGIIMGVRHRRY
PHVQGVQFHPESILTAEGKRLLSNFLRSAKASTAAQPNVSQKPQETVAVVTSGIPTP

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=186, Percent_Identity=57.5268817204301, Blast_Score=228, Evalue=2e-61,
Organism=Escherichia coli, GI1787517, Length=192, Percent_Identity=44.2708333333333, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI1786215, Length=161, Percent_Identity=26.7080745341615, Blast_Score=62, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71992717, Length=145, Percent_Identity=29.6551724137931, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71992710, Length=145, Percent_Identity=29.6551724137931, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI133901714, Length=145, Percent_Identity=29.6551724137931, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322638, Length=187, Percent_Identity=49.1978609625668, Blast_Score=198, Evalue=5e-52,
Organism=Saccharomyces cerevisiae, GI6324361, Length=209, Percent_Identity=30.1435406698565, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase; PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =4.1.3.27; =2.4.2.18 [H]

Molecular weight: Translated: 23680; Mature: 23680

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVVIDNYDSFTYNLVQYLGELGAQLQVFRNDQLSVDDLRRMQPQAVVISPGPGRPEDAG
CEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHCCCCEEEECCCCCCCCCCC
ISLELIRELGPELPILGVCLGHQCIGQVYGGQIVRAPELMHGKTSLIYHRGVGVFEGLSQ
CHHHHHHHCCCCCCEEHHHHHHHHHHHHHCCEEEECCHHHCCCEEEEEECCCCHHHCCCC
PFTATRYHSLVIEPSTCPDELEVTAQTGDGIIMGVRHRRYPHVQGVQFHPESILTAEGKR
CCCCCEEEEEEECCCCCCCCEEEEEECCCEEEEECCCCCCCCCCCCEECCCHHHHHHHHH
LLSNFLRSAKASTAAQPNVSQKPQETVAVVTSGIPTP
HHHHHHHHHHCCCCCCCCCCCCCHHHHEEEECCCCCC
>Mature Secondary Structure
MLVVIDNYDSFTYNLVQYLGELGAQLQVFRNDQLSVDDLRRMQPQAVVISPGPGRPEDAG
CEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHCCCCEEEECCCCCCCCCCC
ISLELIRELGPELPILGVCLGHQCIGQVYGGQIVRAPELMHGKTSLIYHRGVGVFEGLSQ
CHHHHHHHCCCCCCEEHHHHHHHHHHHHHCCEEEECCHHHCCCEEEEEECCCCHHHCCCC
PFTATRYHSLVIEPSTCPDELEVTAQTGDGIIMGVRHRRYPHVQGVQFHPESILTAEGKR
CCCCCEEEEEEECCCCCCCCEEEEEECCCEEEEECCCCCCCCCCCCEECCCHHHHHHHHH
LLSNFLRSAKASTAAQPNVSQKPQETVAVVTSGIPTP
HHHHHHHHHHCCCCCCCCCCCCCHHHHEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685830; 10360571; 7556082 [H]