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The map label for this gene is murG

Identifier: 86609599

GI number: 86609599

Start: 2253304

End: 2254407

Strand: Reverse

Name: murG

Synonym: CYB_2152

Alternate gene names: 86609599

Gene position: 2254407-2253304 (Counterclockwise)

Preceding gene: 86609600

Following gene: 86609598

Centisome position: 74.0

GC content: 63.86

Gene sequence:

>1104_bases
GTGGACACACGCGCCAAGGATCCAGCTTCACGCCCTCGGCTGCTGGTTGCTGCCAGCGGCACTGGTGGCCACATTTTTCC
GGCCTTGGCCGTTGCCGAGCAGTTGCCTGACTGGCAGATTGAATGGCTGGGGGTGCCGGATCGCATGGAAGGGAAGCTGG
TGCGGGAGCGGTATCCCTTGCACCGGGTCGTCATGTCGGGCTGGCAGGGATCCCCTCTCCACAGGCTGCAGGCCTTGGCC
CAACTGGCCCGTGCGACCCTACAAGTGCGCCGACTCCTTATGTCGGGACGGTTTGATATTGTCCTGACCACCGGTGGGTA
CATTGCCGCTCCGGCCATTTTGGCCGCCCGTTCGCTGGGGGTGCCGGTGTTGCTGCACGAGTCCAATTGGATCCCGGGCA
AAGTGACCCGTTGGCTGGGGAGATTTTGTCAGGTGGTGGCGCTGGGCATGGCGGAGACGGCAGAGCATTTGCCAGGGGTG
GCCGCCCAAGTGGTGGGCACGCCAGTGCGGGCCGAGTTCTACACGCCCCAGCCTTTCCCTGCCGACCTCCCCATTCCCGA
CGGGGATCCCCTCATTGTGGTCATGGGGGGCAGCCAAGGGGCGCGGGGCCTCAACCGCATGGTGGCCACCTGTGCCCCAG
CTTGGTTGGAGGCGGGGGCCTGGATTGTGCATTTGACCGGCGGCAGCGAAGCTCAAGATCCGGAAGCCAGGATCCCCAGC
CATCCCCGCTACCGGCCCTTTCCTTTCCGTCGAGATGTAGCTGCCTTGTTGCAGCGGGCCAACTTTGCCATTAGCCGCGC
CGGAGCCATGAGCCTGGCGGAGTTGCTGACCACCGCCACCCCGGCCATTTTGATCCCCTATCCCTTTGCTGCAGAAGATC
ATCAGTATCAGAATGCTCTGGCCTTTGTGGGGCGCGGTGGGGGGGTGGTCATGCGAGAATCCGAAGAGAATCTGGACTTG
CTGCGGCAAACGGTGTTGACCTGGTTGGCCCAGCCGCAGGTGGTTGCCCAAATGGCCGCTCGCTTGCAGGCCGCAGCTCC
TCCCAATGCCAGCAAGGTTCTTGCCCGCCTGTTGCAGGAGATCCGCCAGAGTTCTGCCCGTTAA

Upstream 100 bases:

>100_bases
CCCCGAGCAAGGGTTTATTCTGGGGCAACGGGGCACCCTCTTGCGCTATGTCAGCTCCAACAACTCCTGAAGGTCTCAGG
GATCCCTAACCGGCACACGG

Downstream 100 bases:

>100_bases
GCTGTGGTACAGCCAAGATTGGACAGCCTTTCCCAACGCCCGCCTGTGCTCGCCAAAGCGGCGGAGTCCCCTGCCCTGCT
GGCAGAACTCCCGCCCGCTG

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MDTRAKDPASRPRLLVAASGTGGHIFPALAVAEQLPDWQIEWLGVPDRMEGKLVRERYPLHRVVMSGWQGSPLHRLQALA
QLARATLQVRRLLMSGRFDIVLTTGGYIAAPAILAARSLGVPVLLHESNWIPGKVTRWLGRFCQVVALGMAETAEHLPGV
AAQVVGTPVRAEFYTPQPFPADLPIPDGDPLIVVMGGSQGARGLNRMVATCAPAWLEAGAWIVHLTGGSEAQDPEARIPS
HPRYRPFPFRRDVAALLQRANFAISRAGAMSLAELLTTATPAILIPYPFAAEDHQYQNALAFVGRGGGVVMRESEENLDL
LRQTVLTWLAQPQVVAQMAARLQAAAPPNASKVLARLLQEIRQSSAR

Sequences:

>Translated_367_residues
MDTRAKDPASRPRLLVAASGTGGHIFPALAVAEQLPDWQIEWLGVPDRMEGKLVRERYPLHRVVMSGWQGSPLHRLQALA
QLARATLQVRRLLMSGRFDIVLTTGGYIAAPAILAARSLGVPVLLHESNWIPGKVTRWLGRFCQVVALGMAETAEHLPGV
AAQVVGTPVRAEFYTPQPFPADLPIPDGDPLIVVMGGSQGARGLNRMVATCAPAWLEAGAWIVHLTGGSEAQDPEARIPS
HPRYRPFPFRRDVAALLQRANFAISRAGAMSLAELLTTATPAILIPYPFAAEDHQYQNALAFVGRGGGVVMRESEENLDL
LRQTVLTWLAQPQVVAQMAARLQAAAPPNASKVLARLLQEIRQSSAR
>Mature_367_residues
MDTRAKDPASRPRLLVAASGTGGHIFPALAVAEQLPDWQIEWLGVPDRMEGKLVRERYPLHRVVMSGWQGSPLHRLQALA
QLARATLQVRRLLMSGRFDIVLTTGGYIAAPAILAARSLGVPVLLHESNWIPGKVTRWLGRFCQVVALGMAETAEHLPGV
AAQVVGTPVRAEFYTPQPFPADLPIPDGDPLIVVMGGSQGARGLNRMVATCAPAWLEAGAWIVHLTGGSEAQDPEARIPS
HPRYRPFPFRRDVAALLQRANFAISRAGAMSLAELLTTATPAILIPYPFAAEDHQYQNALAFVGRGGGVVMRESEENLDL
LRQTVLTWLAQPQVVAQMAARLQAAAPPNASKVLARLLQEIRQSSAR

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=358, Percent_Identity=33.5195530726257, Blast_Score=165, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_SYNJB (Q2JJR4)

Other databases:

- EMBL:   CP000240
- RefSeq:   YP_478361.1
- ProteinModelPortal:   Q2JJR4
- SMR:   Q2JJR4
- STRING:   Q2JJR4
- GeneID:   3902585
- GenomeReviews:   CP000240_GR
- KEGG:   cyb:CYB_2152
- TIGR:   CYB_2152
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- PhylomeDB:   Q2JJR4
- ProtClustDB:   CLSK2411659
- BioCyc:   SSP321332:CYB_2152-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 39779; Mature: 39779

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTRAKDPASRPRLLVAASGTGGHIFPALAVAEQLPDWQIEWLGVPDRMEGKLVRERYPL
CCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCHHCCHHHHHHCHH
HRVVMSGWQGSPLHRLQALAQLARATLQVRRLLMSGRFDIVLTTGGYIAAPAILAARSLG
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCC
VPVLLHESNWIPGKVTRWLGRFCQVVALGMAETAEHLPGVAAQVVGTPVRAEFYTPQPFP
CEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEECCCCCC
ADLPIPDGDPLIVVMGGSQGARGLNRMVATCAPAWLEAGAWIVHLTGGSEAQDPEARIPS
CCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCC
HPRYRPFPFRRDVAALLQRANFAISRAGAMSLAELLTTATPAILIPYPFAAEDHQYQNAL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHH
AFVGRGGGVVMRESEENLDLLRQTVLTWLAQPQVVAQMAARLQAAAPPNASKVLARLLQE
HEEECCCCEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
IRQSSAR
HHHHCCC
>Mature Secondary Structure
MDTRAKDPASRPRLLVAASGTGGHIFPALAVAEQLPDWQIEWLGVPDRMEGKLVRERYPL
CCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCHHCCHHHHHHCHH
HRVVMSGWQGSPLHRLQALAQLARATLQVRRLLMSGRFDIVLTTGGYIAAPAILAARSLG
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCC
VPVLLHESNWIPGKVTRWLGRFCQVVALGMAETAEHLPGVAAQVVGTPVRAEFYTPQPFP
CEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEECCCCCC
ADLPIPDGDPLIVVMGGSQGARGLNRMVATCAPAWLEAGAWIVHLTGGSEAQDPEARIPS
CCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCC
HPRYRPFPFRRDVAALLQRANFAISRAGAMSLAELLTTATPAILIPYPFAAEDHQYQNAL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHH
AFVGRGGGVVMRESEENLDLLRQTVLTWLAQPQVVAQMAARLQAAAPPNASKVLARLLQE
HEEECCCCEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
IRQSSAR
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA