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The map label for this gene is moeZ [H]

Identifier: 86609523

GI number: 86609523

Start: 2171192

End: 2172361

Strand: Direct

Name: moeZ [H]

Synonym: CYB_2075

Alternate gene names: 86609523

Gene position: 2171192-2172361 (Clockwise)

Preceding gene: 86609522

Following gene: 86609524

Centisome position: 71.26

GC content: 59.4

Gene sequence:

>1170_bases
ATGTTGAACCTGGATACCAGCCAAGTCAGCCTCTCCCGCGAGGAGATGGAGCGGTTTTCTCGGCATTTGATCCTGCCCGA
GGTGGGCCTAGAAGGACAGAAGCGGCTGAAAGCGGGCAAAGTGCTGTGCATCGGCACAGGCGGCCTTGGCTCGCCCCTGT
TGCTGTACTTGGCGGCAGCCGGCGTGGGGCGGATTGGCATTGTCGATTTTGATGTGGTGGATGTGTCCAACCTGCAGCGG
CAGGTGATCCACGGCACCTCCTGGGTGGGCAAGCCGAAGGTGGAATCGGCCAAGAACCGCATCCTGGAGATCAACCCCCA
CTGTCAAGTGGATGTTTACAACACCGCCCTGAAGGCCCACAACGCACTGGAGCTGTTTGCCAACTATGACGTGATTGTGG
ATGGCACCGATAACTTCCCCACCCGTTACCTGGTGAACGATGCCTGTGTGTTGACGGGCAAGCCCAATGTCTACGGCTCG
ATCTTCCGCTTCGAGGGACAAGCGACGGTCTTCAACTACGAAGATGGGCCCAACTACCGGGATCTCTACCCCGAGCCGCC
CCCACCAGGACTGGTGCCCTCCTGCGCCGAAGGGGGAGTGTTGGGGATCCTCCCCGGCATCATCGGTGTTATTCAAGCTA
CCGAAACCGTGAAGATCCTGCTGGGCGTGGGCACAACCCTAAGTGGGCGGCTGCTGCTTTACGATGCCCTGAACATGAGC
TTCCGGGAGCTGAAGCTGCGCAAAAACCCTGCCACTCCTCCCATCACCCAGCTTATCGACTATGAGCAGTTCTGCGGGAT
CCCGCCAGCCCAAGCCACAGAACAAGCTGGCCAGACAGAGATCCCCGAGATCACTGTGGCCGAGCTGAAAGCGCGGATGG
ATGCTCACCAAGACTTTGTGTTGGTCGATGTGCGCAACCCAAATGAGTGGGAGATAGGCCGGATCCCTGGTGCTCACCTG
ATCCCCCTGCCCCAAATTGAAAACGGCGACGGGGTGGAGCAGGTGCGTCGCCTCCTTAACGGCTCAGAGCTGATCGTCCA
CTGCAAGAGTGGGGCACGCTCGGCCAAAGCCCTGAAGATCCTACAAGCTGCTGGGATCCAAGGAAAAAACCTGCGCGGGG
GGATCCTCGCCTGGGCAGAGGCTTACGATCCCTCGATTCCCAAGTACTGA

Upstream 100 bases:

>100_bases
ACGACGAGGATGTGCGCACGTTGCCCCAAGGCAACAACACCCCCGTGGGAGAACAAGCCGTCATCAGCATCGTTCCCGCT
ATTGCTGGAGGGTTGTGAGC

Downstream 100 bases:

>100_bases
CTCTGCCTTGGGATCCCTACCTGTCGCCCGGTTTGCTCTAGCATAGATCCGGCAGATCCGGTGCCCAGAGCCGGCTGTGC
CAGGTTTTCCCTTTTTGCGT

Product: hypothetical protein

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MLNLDTSQVSLSREEMERFSRHLILPEVGLEGQKRLKAGKVLCIGTGGLGSPLLLYLAAAGVGRIGIVDFDVVDVSNLQR
QVIHGTSWVGKPKVESAKNRILEINPHCQVDVYNTALKAHNALELFANYDVIVDGTDNFPTRYLVNDACVLTGKPNVYGS
IFRFEGQATVFNYEDGPNYRDLYPEPPPPGLVPSCAEGGVLGILPGIIGVIQATETVKILLGVGTTLSGRLLLYDALNMS
FRELKLRKNPATPPITQLIDYEQFCGIPPAQATEQAGQTEIPEITVAELKARMDAHQDFVLVDVRNPNEWEIGRIPGAHL
IPLPQIENGDGVEQVRRLLNGSELIVHCKSGARSAKALKILQAAGIQGKNLRGGILAWAEAYDPSIPKY

Sequences:

>Translated_389_residues
MLNLDTSQVSLSREEMERFSRHLILPEVGLEGQKRLKAGKVLCIGTGGLGSPLLLYLAAAGVGRIGIVDFDVVDVSNLQR
QVIHGTSWVGKPKVESAKNRILEINPHCQVDVYNTALKAHNALELFANYDVIVDGTDNFPTRYLVNDACVLTGKPNVYGS
IFRFEGQATVFNYEDGPNYRDLYPEPPPPGLVPSCAEGGVLGILPGIIGVIQATETVKILLGVGTTLSGRLLLYDALNMS
FRELKLRKNPATPPITQLIDYEQFCGIPPAQATEQAGQTEIPEITVAELKARMDAHQDFVLVDVRNPNEWEIGRIPGAHL
IPLPQIENGDGVEQVRRLLNGSELIVHCKSGARSAKALKILQAAGIQGKNLRGGILAWAEAYDPSIPKY
>Mature_389_residues
MLNLDTSQVSLSREEMERFSRHLILPEVGLEGQKRLKAGKVLCIGTGGLGSPLLLYLAAAGVGRIGIVDFDVVDVSNLQR
QVIHGTSWVGKPKVESAKNRILEINPHCQVDVYNTALKAHNALELFANYDVIVDGTDNFPTRYLVNDACVLTGKPNVYGS
IFRFEGQATVFNYEDGPNYRDLYPEPPPPGLVPSCAEGGVLGILPGIIGVIQATETVKILLGVGTTLSGRLLLYDALNMS
FRELKLRKNPATPPITQLIDYEQFCGIPPAQATEQAGQTEIPEITVAELKARMDAHQDFVLVDVRNPNEWEIGRIPGAHL
IPLPQIENGDGVEQVRRLLNGSELIVHCKSGARSAKALKILQAAGIQGKNLRGGILAWAEAYDPSIPKY

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=412, Percent_Identity=42.9611650485437, Blast_Score=288, Evalue=7e-78,
Organism=Homo sapiens, GI4885649, Length=134, Percent_Identity=30.5970149253731, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI38045942, Length=189, Percent_Identity=30.6878306878307, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI38045944, Length=189, Percent_Identity=30.6878306878307, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1787048, Length=248, Percent_Identity=43.1451612903226, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI87082356, Length=245, Percent_Identity=36.734693877551, Blast_Score=146, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17540406, Length=403, Percent_Identity=38.4615384615385, Blast_Score=261, Evalue=6e-70,
Organism=Caenorhabditis elegans, GI71984476, Length=163, Percent_Identity=34.3558282208589, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193203301, Length=163, Percent_Identity=27.6073619631902, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321903, Length=408, Percent_Identity=37.7450980392157, Blast_Score=238, Evalue=1e-63,
Organism=Saccharomyces cerevisiae, GI6320598, Length=140, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24582879, Length=394, Percent_Identity=40.8629441624365, Blast_Score=308, Evalue=4e-84,
Organism=Drosophila melanogaster, GI24660640, Length=136, Percent_Identity=30.8823529411765, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 42330; Mature: 42330

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNLDTSQVSLSREEMERFSRHLILPEVGLEGQKRLKAGKVLCIGTGGLGSPLLLYLAAA
CCCCCCHHHHCCHHHHHHHHHEEECCCCCCCCHHHHCCCCEEEEECCCCCHHHHHHHHHC
GVGRIGIVDFDVVDVSNLQRQVIHGTSWVGKPKVESAKNRILEINPHCQVDVYNTALKAH
CCCEEEEEEEEEECHHHHHHHHHCCCCCCCCCCHHHHCCCEEEECCCEEEEEHHHHHHHC
NALELFANYDVIVDGTDNFPTRYLVNDACVLTGKPNVYGSIFRFEGQATVFNYEDGPNYR
CCEEEEECCEEEEECCCCCCCEEEECCEEEEECCCCCEEEEEEECCCEEEEECCCCCCCC
DLYPEPPPPGLVPSCAEGGVLGILPGIIGVIQATETVKILLGVGTTLSGRLLLYDALNMS
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCEEEEEHHCCC
FRELKLRKNPATPPITQLIDYEQFCGIPPAQATEQAGQTEIPEITVAELKARMDAHQDFV
CEEHEECCCCCCCCHHHHHCHHHHCCCCCCHHHHHCCCCCCCCCHHHHHHHHHCCCCCEE
LVDVRNPNEWEIGRIPGAHLIPLPQIENGDGVEQVRRLLNGSELIVHCKSGARSAKALKI
EEEECCCCCEEEECCCCCCEEECCCCCCCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHH
LQAAGIQGKNLRGGILAWAEAYDPSIPKY
HHHCCCCCCCCCCCEEEEEHHCCCCCCCC
>Mature Secondary Structure
MLNLDTSQVSLSREEMERFSRHLILPEVGLEGQKRLKAGKVLCIGTGGLGSPLLLYLAAA
CCCCCCHHHHCCHHHHHHHHHEEECCCCCCCCHHHHCCCCEEEEECCCCCHHHHHHHHHC
GVGRIGIVDFDVVDVSNLQRQVIHGTSWVGKPKVESAKNRILEINPHCQVDVYNTALKAH
CCCEEEEEEEEEECHHHHHHHHHCCCCCCCCCCHHHHCCCEEEECCCEEEEEHHHHHHHC
NALELFANYDVIVDGTDNFPTRYLVNDACVLTGKPNVYGSIFRFEGQATVFNYEDGPNYR
CCEEEEECCEEEEECCCCCCCEEEECCEEEEECCCCCEEEEEEECCCEEEEECCCCCCCC
DLYPEPPPPGLVPSCAEGGVLGILPGIIGVIQATETVKILLGVGTTLSGRLLLYDALNMS
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCEEEEEHHCCC
FRELKLRKNPATPPITQLIDYEQFCGIPPAQATEQAGQTEIPEITVAELKARMDAHQDFV
CEEHEECCCCCCCCHHHHHCHHHHCCCCCCHHHHHCCCCCCCCCHHHHHHHHHCCCCCEE
LVDVRNPNEWEIGRIPGAHLIPLPQIENGDGVEQVRRLLNGSELIVHCKSGARSAKALKI
EEEECCCCCEEEECCCCCCEEECCCCCCCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHH
LQAAGIQGKNLRGGILAWAEAYDPSIPKY
HHHCCCCCCCCCCCEEEEEHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]