Click here to switch to the map view.

The map label for this gene is thiL [H]

Identifier: 86609323

GI number: 86609323

Start: 1950554

End: 1951576

Strand: Reverse

Name: thiL [H]

Synonym: CYB_1867

Alternate gene names: 86609323

Gene position: 1951576-1950554 (Counterclockwise)

Preceding gene: 86609324

Following gene: 86609322

Centisome position: 64.06

GC content: 63.15

Gene sequence:

>1023_bases
TTGTTCTCCGGTCTTCCTGACAGTGCTTCCCCACAAAACGGCAATCCTTCCCCCCTACCCATCTCGGCAATTGGGGAGGC
AGGGCTGCTGCAGATCGTGCAGCGCTACTGTCCGGCCCAGGTGGTGGGAGACGATGCGGCGGTGTTGGCTGCTCCGGAGG
GGCAGTTGGTGGTGACAACCGATGTGTTGGTGGAGGGAGTTCACTTCAGCGATCTGACGACCCCGGCCCATGCGGTGGGC
TGGCGCGCGGTGGCCGCCAATCTGTCGGATCTGGCCGCGATGGGATCCCGTCCGCAGGCGTTGGTGGTGGGTTTGGGCTT
GCCGGGCTCCACACCGGTTGCTTGGGTGGAGGAGCTTTATCAAGGGATGCGGGACTGTTGCGCCCGCTGGGAATGCCAAC
TGGTGGGAGGGGATCTGTGTCGGTCGCCGCATCGATTTGTGGCAATCACGGCCCTGGGATCGGTGCAGCCGGGGCGGGCC
ATTCAGCGCAGACGGGCTCAACCCGGCGATTGGCTGGTGGTAACAGGGCCCCACGGAGATGCGCGGGCAGGCTTGGAGCT
GCTTCTCCATCCTGAACAGGGATCCTCAGCTACGGCGGCCGAGCGCGAGCAGTTGATCAGGGCTCACCAATACCCACGCC
CGCGCCTGGATCTGGTGCCCCTCTTGGAAAGGATCCCGGATCCCTTGCGCATTGCCGGCATGGATACCAGCGACGGTTTG
GCAGATGCCCTGGTGCAGGTGTGTCAGGCCAGTGGGGTGGAGGCAAGGATTGCCGTGGAGCGGATCCCGATTTCAGAAGC
TTTGCGGCAGGCTTTTCCGGCCCAAGCCTTGGAATGGGCGCTTTATGGGGGCGAAGATTTTGAGCTGCTCCTCAGTGCCG
AGGTGTCGGTGGCCAAGCATCTGTTGGAAAGATTGCCGGGGGCCGTTTGGATTGGAGAAGTGACAGGCTGGGATCCGCAG
GGAACCGTCTGGCTGAAGGACGGGCAGGCCCTCAGTCGTCAGCAAGCCTTCCAGCATTTCTAA

Upstream 100 bases:

>100_bases
CCTGTGGCGTGCAGGCGGGATCCTTGGAAATATCCAACAAGAACCCATCATCCATCAGCTTTTTCAGCTTTGCTATCCTC
GCTACCCTCAGAGGTCTGTC

Downstream 100 bases:

>100_bases
GAGGCGTTGTGCTGCAGGATGGTCACCCAAACTGCCAACAGTTGAAAACAAATCGACTTGTGGGAGAAAACAAGCCCTAG
GAAGGATTCGATAACCTAGA

Product: thiamine monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MFSGLPDSASPQNGNPSPLPISAIGEAGLLQIVQRYCPAQVVGDDAAVLAAPEGQLVVTTDVLVEGVHFSDLTTPAHAVG
WRAVAANLSDLAAMGSRPQALVVGLGLPGSTPVAWVEELYQGMRDCCARWECQLVGGDLCRSPHRFVAITALGSVQPGRA
IQRRRAQPGDWLVVTGPHGDARAGLELLLHPEQGSSATAAEREQLIRAHQYPRPRLDLVPLLERIPDPLRIAGMDTSDGL
ADALVQVCQASGVEARIAVERIPISEALRQAFPAQALEWALYGGEDFELLLSAEVSVAKHLLERLPGAVWIGEVTGWDPQ
GTVWLKDGQALSRQQAFQHF

Sequences:

>Translated_340_residues
MFSGLPDSASPQNGNPSPLPISAIGEAGLLQIVQRYCPAQVVGDDAAVLAAPEGQLVVTTDVLVEGVHFSDLTTPAHAVG
WRAVAANLSDLAAMGSRPQALVVGLGLPGSTPVAWVEELYQGMRDCCARWECQLVGGDLCRSPHRFVAITALGSVQPGRA
IQRRRAQPGDWLVVTGPHGDARAGLELLLHPEQGSSATAAEREQLIRAHQYPRPRLDLVPLLERIPDPLRIAGMDTSDGL
ADALVQVCQASGVEARIAVERIPISEALRQAFPAQALEWALYGGEDFELLLSAEVSVAKHLLERLPGAVWIGEVTGWDPQ
GTVWLKDGQALSRQQAFQHF
>Mature_340_residues
MFSGLPDSASPQNGNPSPLPISAIGEAGLLQIVQRYCPAQVVGDDAAVLAAPEGQLVVTTDVLVEGVHFSDLTTPAHAVG
WRAVAANLSDLAAMGSRPQALVVGLGLPGSTPVAWVEELYQGMRDCCARWECQLVGGDLCRSPHRFVAITALGSVQPGRA
IQRRRAQPGDWLVVTGPHGDARAGLELLLHPEQGSSATAAEREQLIRAHQYPRPRLDLVPLLERIPDPLRIAGMDTSDGL
ADALVQVCQASGVEARIAVERIPISEALRQAFPAQALEWALYGGEDFELLLSAEVSVAKHLLERLPGAVWIGEVTGWDPQ
GTVWLKDGQALSRQQAFQHF

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=307, Percent_Identity=37.785016286645, Blast_Score=162, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 36343; Mature: 36343

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSGLPDSASPQNGNPSPLPISAIGEAGLLQIVQRYCPAQVVGDDAAVLAAPEGQLVVTT
CCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHCCCEEECCCCEEEECCCCCEEEEH
DVLVEGVHFSDLTTPAHAVGWRAVAANLSDLAAMGSRPQALVVGLGLPGSTPVAWVEELY
HHHHCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHH
QGMRDCCARWECQLVGGDLCRSPHRFVAITALGSVQPGRAIQRRRAQPGDWLVVTGPHGD
HHHHHHHHCCEEEEECCHHCCCCCCEEEEEEECCCCCCHHHHHHCCCCCCEEEEECCCCC
ARAGLELLLHPEQGSSATAAEREQLIRAHQYPRPRLDLVPLLERIPDPLRIAGMDTSDGL
CCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEECCCCCCCH
ADALVQVCQASGVEARIAVERIPISEALRQAFPAQALEWALYGGEDFELLLSAEVSVAKH
HHHHHHHHHHCCCEEEEEEECCCHHHHHHHHCCHHHHHEEEECCCCEEEEEEHHHHHHHH
LLERLPGAVWIGEVTGWDPQGTVWLKDGQALSRQQAFQHF
HHHHCCCEEEEECCCCCCCCCEEEEECCHHHHHHHHHHCC
>Mature Secondary Structure
MFSGLPDSASPQNGNPSPLPISAIGEAGLLQIVQRYCPAQVVGDDAAVLAAPEGQLVVTT
CCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHCCCEEECCCCEEEECCCCCEEEEH
DVLVEGVHFSDLTTPAHAVGWRAVAANLSDLAAMGSRPQALVVGLGLPGSTPVAWVEELY
HHHHCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHH
QGMRDCCARWECQLVGGDLCRSPHRFVAITALGSVQPGRAIQRRRAQPGDWLVVTGPHGD
HHHHHHHHCCEEEEECCHHCCCCCCEEEEEEECCCCCCHHHHHHCCCCCCEEEEECCCCC
ARAGLELLLHPEQGSSATAAEREQLIRAHQYPRPRLDLVPLLERIPDPLRIAGMDTSDGL
CCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEECCCCCCCH
ADALVQVCQASGVEARIAVERIPISEALRQAFPAQALEWALYGGEDFELLLSAEVSVAKH
HHHHHHHHHHCCCEEEEEEECCCHHHHHHHHCCHHHHHEEEECCCCEEEEEEHHHHHHHH
LLERLPGAVWIGEVTGWDPQGTVWLKDGQALSRQQAFQHF
HHHHCCCEEEEECCCCCCCCCEEEEECCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA