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The map label for this gene is ymxG [H]

Identifier: 86608216

GI number: 86608216

Start: 752642

End: 753946

Strand: Reverse

Name: ymxG [H]

Synonym: CYB_0732

Alternate gene names: 86608216

Gene position: 753946-752642 (Counterclockwise)

Preceding gene: 86608217

Following gene: 86608215

Centisome position: 24.75

GC content: 61.23

Gene sequence:

>1305_bases
TTGAACCGCTTTCCTCGTCTCTTGCCCGCCTACACCCACCGACTGAGCAACGGGCTAGGCGTTATCGTTCATCCCATCCC
AATTGCCGATTCTGTAACCGTTGACGTCTGGGTACGGACAGGTGGACGCCATGAGCCGCCGGAGTGGCTGGGCCTATCCC
ATTTTTTGGAACACATGGTGTTTAAGGGCAGCGAGCGGCTGGCCCCTGGTGAGCTGGATTGGGCCGTGGAAGGACGGGGC
GGAGTTACCAATGCTGCCACCGGCCAAGACTACACCCATTACTACATTACGGTGGCTGCTGCTGACCTAGCGGATACCTT
GCCCTACTTGGCAGAGGTGGTTTTGCGGGCCGGGATCCCGGATCCAGAGTTTGAGCGGGAGCGGCAGGTGGTTCTGGAGG
AAATTCGCCGCGCCGCCGACAACCCTGATTACACGGCCTATCAGCTTTTGATGCAGACTGCCTATGGGGAGCATCCCTAT
GGACGACCGGTGTTGGGCACACCGGAAAGCTTGATGCAACTGACCCCTGAGGTGATGCGCGCTTACCACCGCGCTTGGTA
TCGGCCTGAATCCATGACGGTGGTGGTGACGGGTGGCATCGATCCCGAGCGGGCGTTGGCCTTGGTGGAGGAGCAGTTTG
GCAGCTCTGCCGCCGGGCCAGCACCGGCCAGCCCCCCCATCCCGCCCCAGCCTCGTCCCCAAGGGATCCTGCGCCGGGAG
AGCGACCATGCCCGCTTGGAGCAAGCCCGTCTGAAATTGGCCTGGCCTACCGTTGGCATTGACGATTGGCAGCAAGCCTG
TGGCCTGGAGATGTTGGCTTCTCTGCTGGGAGATGGCCGTACTTCGCGGCTGGTGCATCTGCTGCGGGAACAGCGGGGCT
GGGTGAGGGCCATTGGCTGTTCTTCGCTGGTGTTGAAGGAGGGGGGACTGTTTTGTATCGGCGCTCAGCTGGAGCCGAAG
GATGTGGCGCGGGTGGAGGCGACGATCCTGCACGAGATTGAAAAGCTGCAGCAGGATGGCATCGGCCAAGCGGAGTTGGA
TCGCACCCGGCGTATGCTCACCCATGAGTTCCTGTTCTCCGCCGAGTCCCCCAGCCAATTGGCGGGCATCTATGGCTACT
ACGAGACGTTGGGCGGGGTGCAACGCATTCAAGAGTACCTGGAGCTGGTGCAATCTTTTACCCCGGCTCAGATCCGGGAA
TTGGCCCAGCAGTACTTGTCTTTGGAGGCCTATGTGGTCACCGTTCTCAAGCCGACTGCCCTGGGTACAGCGGCGGCTTC
GGAGCTGCAACTGGCTTGCCGTTAA

Upstream 100 bases:

>100_bases
GCAAGCCGGGGAGAGAAGACCAAGAAAAGTAGTCTCAGATACTATTTCCGGGAGACCCTCTCCATCTACAATTAAGACTG
TTCTCCATCAATTAAGAATT

Downstream 100 bases:

>100_bases
GCGCCGCCTTGGCGCTCCGGACTCTTGATTTTCGGATTTTGGACGGGATCCCTTGCCTGCATGAACTCTGCTCTGCTTGC
CACCCAACGTGGCCGTTTAC

Product: M16B family peptidase

Products: NA

Alternate protein names: ORFP [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MNRFPRLLPAYTHRLSNGLGVIVHPIPIADSVTVDVWVRTGGRHEPPEWLGLSHFLEHMVFKGSERLAPGELDWAVEGRG
GVTNAATGQDYTHYYITVAAADLADTLPYLAEVVLRAGIPDPEFERERQVVLEEIRRAADNPDYTAYQLLMQTAYGEHPY
GRPVLGTPESLMQLTPEVMRAYHRAWYRPESMTVVVTGGIDPERALALVEEQFGSSAAGPAPASPPIPPQPRPQGILRRE
SDHARLEQARLKLAWPTVGIDDWQQACGLEMLASLLGDGRTSRLVHLLREQRGWVRAIGCSSLVLKEGGLFCIGAQLEPK
DVARVEATILHEIEKLQQDGIGQAELDRTRRMLTHEFLFSAESPSQLAGIYGYYETLGGVQRIQEYLELVQSFTPAQIRE
LAQQYLSLEAYVVTVLKPTALGTAAASELQLACR

Sequences:

>Translated_434_residues
MNRFPRLLPAYTHRLSNGLGVIVHPIPIADSVTVDVWVRTGGRHEPPEWLGLSHFLEHMVFKGSERLAPGELDWAVEGRG
GVTNAATGQDYTHYYITVAAADLADTLPYLAEVVLRAGIPDPEFERERQVVLEEIRRAADNPDYTAYQLLMQTAYGEHPY
GRPVLGTPESLMQLTPEVMRAYHRAWYRPESMTVVVTGGIDPERALALVEEQFGSSAAGPAPASPPIPPQPRPQGILRRE
SDHARLEQARLKLAWPTVGIDDWQQACGLEMLASLLGDGRTSRLVHLLREQRGWVRAIGCSSLVLKEGGLFCIGAQLEPK
DVARVEATILHEIEKLQQDGIGQAELDRTRRMLTHEFLFSAESPSQLAGIYGYYETLGGVQRIQEYLELVQSFTPAQIRE
LAQQYLSLEAYVVTVLKPTALGTAAASELQLACR
>Mature_434_residues
MNRFPRLLPAYTHRLSNGLGVIVHPIPIADSVTVDVWVRTGGRHEPPEWLGLSHFLEHMVFKGSERLAPGELDWAVEGRG
GVTNAATGQDYTHYYITVAAADLADTLPYLAEVVLRAGIPDPEFERERQVVLEEIRRAADNPDYTAYQLLMQTAYGEHPY
GRPVLGTPESLMQLTPEVMRAYHRAWYRPESMTVVVTGGIDPERALALVEEQFGSSAAGPAPASPPIPPQPRPQGILRRE
SDHARLEQARLKLAWPTVGIDDWQQACGLEMLASLLGDGRTSRLVHLLREQRGWVRAIGCSSLVLKEGGLFCIGAQLEPK
DVARVEATILHEIEKLQQDGIGQAELDRTRRMLTHEFLFSAESPSQLAGIYGYYETLGGVQRIQEYLELVQSFTPAQIRE
LAQQYLSLEAYVVTVLKPTALGTAAASELQLACR

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=229, Percent_Identity=28.82096069869, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI155969707, Length=384, Percent_Identity=26.0416666666667, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI46593007, Length=184, Percent_Identity=28.2608695652174, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI24308013, Length=421, Percent_Identity=23.9904988123515, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI1787770, Length=369, Percent_Identity=24.6612466124661, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI2367164, Length=370, Percent_Identity=23.2432432432432, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71999683, Length=341, Percent_Identity=24.0469208211144, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17553678, Length=409, Percent_Identity=23.4718826405868, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI72001443, Length=210, Percent_Identity=26.1904761904762, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI25146566, Length=193, Percent_Identity=26.4248704663212, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71994338, Length=193, Percent_Identity=26.4248704663212, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI25146563, Length=193, Percent_Identity=26.4248704663212, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI32566665, Length=193, Percent_Identity=26.4248704663212, Blast_Score=75, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6323192, Length=222, Percent_Identity=27.4774774774775, Blast_Score=110, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6323421, Length=311, Percent_Identity=23.1511254019293, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6321813, Length=227, Percent_Identity=24.2290748898678, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21357875, Length=210, Percent_Identity=28.0952380952381, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24646943, Length=210, Percent_Identity=28.0952380952381, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI221513245, Length=371, Percent_Identity=23.4501347708895, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 48130; Mature: 48130

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00107 PROTEIN_KINASE_ATP ; PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRFPRLLPAYTHRLSNGLGVIVHPIPIADSVTVDVWVRTGGRHEPPEWLGLSHFLEHMV
CCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEEECCCCCCCHHHCCHHHHHHHHH
FKGSERLAPGELDWAVEGRGGVTNAATGQDYTHYYITVAAADLADTLPYLAEVVLRAGIP
HCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHCCCC
DPEFERERQVVLEEIRRAADNPDYTAYQLLMQTAYGEHPYGRPVLGTPESLMQLTPEVMR
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCHHHHH
AYHRAWYRPESMTVVVTGGIDPERALALVEEQFGSSAAGPAPASPPIPPQPRPQGILRRE
HHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCC
SDHARLEQARLKLAWPTVGIDDWQQACGLEMLASLLGDGRTSRLVHLLREQRGWVRAIGC
CHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECC
SSLVLKEGGLFCIGAQLEPKDVARVEATILHEIEKLQQDGIGQAELDRTRRMLTHEFLFS
HHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHC
AESPSQLAGIYGYYETLGGVQRIQEYLELVQSFTPAQIRELAQQYLSLEAYVVTVLKPTA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEEECCHH
LGTAAASELQLACR
HHHHHHHHHHHHCC
>Mature Secondary Structure
MNRFPRLLPAYTHRLSNGLGVIVHPIPIADSVTVDVWVRTGGRHEPPEWLGLSHFLEHMV
CCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEEECCCCCCCHHHCCHHHHHHHHH
FKGSERLAPGELDWAVEGRGGVTNAATGQDYTHYYITVAAADLADTLPYLAEVVLRAGIP
HCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHCCCC
DPEFERERQVVLEEIRRAADNPDYTAYQLLMQTAYGEHPYGRPVLGTPESLMQLTPEVMR
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCHHHHH
AYHRAWYRPESMTVVVTGGIDPERALALVEEQFGSSAAGPAPASPPIPPQPRPQGILRRE
HHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCC
SDHARLEQARLKLAWPTVGIDDWQQACGLEMLASLLGDGRTSRLVHLLREQRGWVRAIGC
CHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECC
SSLVLKEGGLFCIGAQLEPKDVARVEATILHEIEKLQQDGIGQAELDRTRRMLTHEFLFS
HHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHC
AESPSQLAGIYGYYETLGGVQRIQEYLELVQSFTPAQIRELAQQYLSLEAYVVTVLKPTA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEEECCHH
LGTAAASELQLACR
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 8098035 [H]