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The map label for this gene is ymxG [H]

Identifier: 86608215

GI number: 86608215

Start: 751292

End: 752581

Strand: Reverse

Name: ymxG [H]

Synonym: CYB_0731

Alternate gene names: 86608215

Gene position: 752581-751292 (Counterclockwise)

Preceding gene: 86608216

Following gene: 86608214

Centisome position: 24.7

GC content: 61.24

Gene sequence:

>1290_bases
ATGAACTCTGCTCTGCTTGCCACCCAACGTGGCCGTTTACAGCGCGTCCTTTTGGCCAATGGCATCACGCTGTTGCTGGG
CCAGAACCCAACGGTGGAGATCTTGGCTGCCCACTGTTTTTTCCGCGGTGGTAGCCGGGCAGAGCGGCCGCAACAGGCGG
GGGTGAGCCACTTGATGGCGGCTGTCCTCACCAAAGGCACGCATCGGCGCAACTCCCAGGCCATTGCTGCTGCGGTGGAA
TCGCTGGGAGCCTCGCTATCGGTGGACAGTTCTGCCGACTATTTCGAGGTGAGCCTGCGCTGTGTGGCTGCCGATTTCCC
GGAGTTGCTGGATTTGCTTGCGGAGACGCTGCGGGATCCCAGTTTTCCTGAAGAGGAGGTGGCGCGAGAGCAGGGGTTGA
TGCTGCAGGCCATCCGCGCCCAACAGGAACGGCCCTTCAGCTTGGCTTTCGAGCAGGTGCAACAAGCCCTCTATGGGGAT
CATCCCTACGCTCTGCCGGGGTTGGGACGGCTGGAAACGGTGGGATCCCTGACCCGCGAGGATTTGGTAGCCTATCACGC
GGCCTACTGTCGTCCCAATGGAATGGTGATGGTGGTGATCGGCCCAGAGCCGCCGGAGCAGATGGCTGCCCAGGTGGAAG
CGGCTTTGGGAGACTGGGTTGTTCCCGGCCCCTCTCCAGAGGATCGGGATGTTCCCCTGCCCCCTCTGAGGGATCCCCAA
CTGCTGAGGTTGCCCCAGCCCACTCAGCAGACAACAATCTTGATTGGGTTTCGCGGATCCCCTGCTGCTTCTGCGGATTA
TCCGGCCCTGAAACTGTTGGCCACCTACTTGGGCAGCGGTCTATCCAGCCGTCTGTTTGTGGAACTGCGGGAGCGCTGTG
GCCTGGCCTATGAGGTCTCGGCTTTTTTTGCCACCCGCCGGGATCCCGCCCCTTTTGGGGTTTACATGGGCACTGCAGCA
GAGAACACCCAGGTGGCTCTGGAACGCCTACAAGCAGAAATCCACCGTCTGCAGGCCAATCCGCTCGACCTGGCAGAGGT
GGAAATGGCGCAGCGCAAACTTCTGGGCCAGTATGCCCTCAGCAAACAAACCAATGCCCAGGTGGCTCAACTGGCGGGCT
GGTACGAGATTTTGGGCTTGGGCATGGAGTTTGACCGGCAGTATTTGCAGGGGGTCAGGCAGCTCACCCCAGAGCAGCTC
CACCAAGCCGCAAAGACCTACCTGACCCCCCCGGCCATTGCTCTGGTGGGGCCGGAAGCCGCCTTGGCAGAGGTTGAGCT
GGTGTTTTAA

Upstream 100 bases:

>100_bases
TACAGCGGCGGCTTCGGAGCTGCAACTGGCTTGCCGTTAAGCGCCGCCTTGGCGCTCCGGACTCTTGATTTTCGGATTTT
GGACGGGATCCCTTGCCTGC

Downstream 100 bases:

>100_bases
GCTGAGCAAACCATGAGGAAAACTAAGATCTGGCAAACATGGCCATTTCGATTCAAACGGGGACATTGCGCCCACACCTC
AATAAAACACCTAAATAAAA

Product: M16 family peptidase

Products: NA

Alternate protein names: ORFP [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MNSALLATQRGRLQRVLLANGITLLLGQNPTVEILAAHCFFRGGSRAERPQQAGVSHLMAAVLTKGTHRRNSQAIAAAVE
SLGASLSVDSSADYFEVSLRCVAADFPELLDLLAETLRDPSFPEEEVAREQGLMLQAIRAQQERPFSLAFEQVQQALYGD
HPYALPGLGRLETVGSLTREDLVAYHAAYCRPNGMVMVVIGPEPPEQMAAQVEAALGDWVVPGPSPEDRDVPLPPLRDPQ
LLRLPQPTQQTTILIGFRGSPAASADYPALKLLATYLGSGLSSRLFVELRERCGLAYEVSAFFATRRDPAPFGVYMGTAA
ENTQVALERLQAEIHRLQANPLDLAEVEMAQRKLLGQYALSKQTNAQVAQLAGWYEILGLGMEFDRQYLQGVRQLTPEQL
HQAAKTYLTPPAIALVGPEAALAEVELVF

Sequences:

>Translated_429_residues
MNSALLATQRGRLQRVLLANGITLLLGQNPTVEILAAHCFFRGGSRAERPQQAGVSHLMAAVLTKGTHRRNSQAIAAAVE
SLGASLSVDSSADYFEVSLRCVAADFPELLDLLAETLRDPSFPEEEVAREQGLMLQAIRAQQERPFSLAFEQVQQALYGD
HPYALPGLGRLETVGSLTREDLVAYHAAYCRPNGMVMVVIGPEPPEQMAAQVEAALGDWVVPGPSPEDRDVPLPPLRDPQ
LLRLPQPTQQTTILIGFRGSPAASADYPALKLLATYLGSGLSSRLFVELRERCGLAYEVSAFFATRRDPAPFGVYMGTAA
ENTQVALERLQAEIHRLQANPLDLAEVEMAQRKLLGQYALSKQTNAQVAQLAGWYEILGLGMEFDRQYLQGVRQLTPEQL
HQAAKTYLTPPAIALVGPEAALAEVELVF
>Mature_429_residues
MNSALLATQRGRLQRVLLANGITLLLGQNPTVEILAAHCFFRGGSRAERPQQAGVSHLMAAVLTKGTHRRNSQAIAAAVE
SLGASLSVDSSADYFEVSLRCVAADFPELLDLLAETLRDPSFPEEEVAREQGLMLQAIRAQQERPFSLAFEQVQQALYGD
HPYALPGLGRLETVGSLTREDLVAYHAAYCRPNGMVMVVIGPEPPEQMAAQVEAALGDWVVPGPSPEDRDVPLPPLRDPQ
LLRLPQPTQQTTILIGFRGSPAASADYPALKLLATYLGSGLSSRLFVELRERCGLAYEVSAFFATRRDPAPFGVYMGTAA
ENTQVALERLQAEIHRLQANPLDLAEVEMAQRKLLGQYALSKQTNAQVAQLAGWYEILGLGMEFDRQYLQGVRQLTPEQL
HQAAKTYLTPPAIALVGPEAALAEVELVF

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=413, Percent_Identity=23.0024213075061, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI46593007, Length=226, Percent_Identity=24.3362831858407, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71999683, Length=327, Percent_Identity=22.0183486238532, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17553678, Length=366, Percent_Identity=21.3114754098361, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6323192, Length=403, Percent_Identity=23.5732009925558, Blast_Score=100, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6321813, Length=356, Percent_Identity=25, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21357875, Length=178, Percent_Identity=23.5955056179775, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24646943, Length=178, Percent_Identity=23.5955056179775, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 46730; Mature: 46730

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSALLATQRGRLQRVLLANGITLLLGQNPTVEILAAHCFFRGGSRAERPQQAGVSHLMA
CCCCCEEHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
AVLTKGTHRRNSQAIAAAVESLGASLSVDSSADYFEVSLRCVAADFPELLDLLAETLRDP
HHHHCCCCCCCHHHHHHHHHHHCCCEECCCCCCEEHHHHHHHHCCHHHHHHHHHHHHCCC
SFPEEEVAREQGLMLQAIRAQQERPFSLAFEQVQQALYGDHPYALPGLGRLETVGSLTRE
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
DLVAYHAAYCRPNGMVMVVIGPEPPEQMAAQVEAALGDWVVPGPSPEDRDVPLPPLRDPQ
HHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCEECCCCCCCCCCCCCCCCCCCC
LLRLPQPTQQTTILIGFRGSPAASADYPALKLLATYLGSGLSSRLFVELRERCGLAYEVS
EEECCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEHH
AFFATRRDPAPFGVYMGTAAENTQVALERLQAEIHRLQANPLDLAEVEMAQRKLLGQYAL
HHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
SKQTNAQVAQLAGWYEILGLGMEFDRQYLQGVRQLTPEQLHQAAKTYLTPPAIALVGPEA
CCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEECCCH
ALAEVELVF
HHHEEEEEC
>Mature Secondary Structure
MNSALLATQRGRLQRVLLANGITLLLGQNPTVEILAAHCFFRGGSRAERPQQAGVSHLMA
CCCCCEEHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
AVLTKGTHRRNSQAIAAAVESLGASLSVDSSADYFEVSLRCVAADFPELLDLLAETLRDP
HHHHCCCCCCCHHHHHHHHHHHCCCEECCCCCCEEHHHHHHHHCCHHHHHHHHHHHHCCC
SFPEEEVAREQGLMLQAIRAQQERPFSLAFEQVQQALYGDHPYALPGLGRLETVGSLTRE
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
DLVAYHAAYCRPNGMVMVVIGPEPPEQMAAQVEAALGDWVVPGPSPEDRDVPLPPLRDPQ
HHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCEECCCCCCCCCCCCCCCCCCCC
LLRLPQPTQQTTILIGFRGSPAASADYPALKLLATYLGSGLSSRLFVELRERCGLAYEVS
EEECCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEHH
AFFATRRDPAPFGVYMGTAAENTQVALERLQAEIHRLQANPLDLAEVEMAQRKLLGQYAL
HHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
SKQTNAQVAQLAGWYEILGLGMEFDRQYLQGVRQLTPEQLHQAAKTYLTPPAIALVGPEA
CCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEECCCH
ALAEVELVF
HHHEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 8098035 [H]