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The map label for this gene is pilQ [H]

Identifier: 86607978

GI number: 86607978

Start: 496114

End: 498204

Strand: Reverse

Name: pilQ [H]

Synonym: CYB_0484

Alternate gene names: 86607978

Gene position: 498204-496114 (Counterclockwise)

Preceding gene: 86607979

Following gene: 86607976

Centisome position: 16.35

GC content: 55.33

Gene sequence:

>2091_bases
ATGATGAACCGTCGAGTTGCTTATGGGTGTGCGTTGGGCTTGATCCTGTCCCTGCCCCCATTGGCCTTAGAAAGCCGGGT
CAATGAGGCAGCCGCTCAACAGTTGACCTCCGCAAACCCGCAACGCCTCAGCCGCATCACAGATATCCGCCTGGTGCCCA
ACGGCAACCGCATGCAGTTGGAGATCAACACCGAAGGGGGCGCTCGCCCACAGGTGTTCTTTACCCAGCAGGGACAATCT
TGGATCGGGGACATCACCAATGCTCAATTGAGCGGAAGCCAGGGCCGCTATCGCCAAGAGTCTCCCCTGCCAGGGGTGCG
CTTCATTGAGGCCTGGCAGTTGAGCAACGACAGCGTGCGGATAGAAATAGCCGGTGTGGCCGCAGCTCCCCAAGGCTTGC
TGGCTCGGCGCAGCCCGACGCAGTTGGTCTTCGACTTTGAGGGCCTACCCTCTGCTCCACCGGCCCCCCTAGCGGCGGTT
CCCCCTCAACCCTCGTCCAACCCAGTAGCGCCCGGCCAACCGGCGTCACTAAACCGACCTCAGCCCGTGGCTCCTGCTCC
TCAGCCCGCAGCTCCTGCCCCTGCCTCCCAACCGGTCGCTCAAAACCCTGCCCCTCCGCAGACAACTCAAGCGGCTCCTC
CTGCACCTGCTGTTCCTGCTGCACCCGTGATTTCTCAGGTCCCCCCTGTGGGCCAGCTCAACCAACCTCAATTGCCGCCG
GGAAGTTTGCCCACCGAATCTCCTTTTCAGGGGAGAGCTGTGGCTCCTCCTGCTGGCGATATTGCCGTTGGCACAATCCT
GCCTGATCCACCTACAGTGGATCTCGGATCCAATGCCAGGATTAGCTTGACCTTGAAAGATGCTCCTGTGGGCGATGTGC
TGAGCTTGTTGGTGCGGCGAGCAGGGTTGAATGTGGTGCTCAACGACGTCCCACCCGATCTAACCATCTCTCTGGATGTG
CAAGACTCGCCCTTACAGGAGACATTCAACTTTATCTTGCGGCTAAAACAGTTGCAAGCCCAGCGAAGGGGCCAAACCGT
ATTTGTTGGACAAAACCTGCCAGGGGTGACTGGGATCCTGGTGCGCAATTACCGCGTGAATCAGGCAGTCGCCACCGATT
TGGCCAGTCGGCTGGAAGAAGTTTTGAACGCCGTTGCTCCCGGTGCCCAATTCGTTGTGGACGAGCGCACCAACTCCATT
ACGGTGATCGGCAACTCGCGGCAGCAGGACATCGCGGCTGCTCAGATTGCCCAATTGGATGTGCGTCGGCGACAGGTTTT
GATTTCCCTGAGAGCAGTTGATATTCGCTTGGACAAAAACGAAAGCTTATCAGTTAACTTGGGAGGGGCATCTGGCAACT
TTGCCCTTGGAACCTTGGGAGACGCCAACTTTGGTGGACGACCGCTCAATCAACCTGCGGGATCCTCGGTAAGCTCTATC
GGCCCTGCAGGCCCATCAGGATCCATCACGGGAATATTTAACACTCTCAACCGGCTGCAGCAGTCTTTGGCTCTAAGAGT
GCAGTCTGCAATACAAAATGGAACTGGAAAAATTCTAACTGACCCCAAAGTTGTGGTGGCAGATGGCGGATCCAGTCGAA
TTAGCATTGCAACCAGCGTGCCCGTTAACGTTGAAACCATCACCATACCCCAGGGCGAAAACCAGCCTCCAGTTGTTACT
CAGCGTTTGCAGCGAGAGGATGCTGGGGTTATCCTTGACGTCTCAGAAGTTAGAATAGATGACAATGGGTTTGTTACCCT
GACCATTCAGCCGGAAATTTCTATTCCTGTACCCAGTCAAATATTGGGAGGCGGAGACTTTGCAGGCATTCTACTTTTCA
ATATTGACAGGAGGCAGCTACAAGCATCTCAGCTCAGGTTAAGAGATGGGCAAACCTTTATTATTGCTGGCCTCATTCAA
GACAGGGACATCGTTGACGTTCAAAAAGTGCCTTTCCTAGGCGACTTGCCTCTTTTGGGTGCTTTGTTCCGCTCTCAGAG
TGTGAATAACGAGCGCAATGAGGTGGTCTTCATGCTAACGCCCTACATTATGGATGATAATGTTGCTTTTGGTCTTCCTC
CCAATCCGTAA

Upstream 100 bases:

>100_bases
ATTTCGGCTTTGATCAGGGAAGCACGGGGTGAACGAGGCCAAAGGCACCCGTGGCGAGGTGAAGCAAGAATACGACTGGG
TGAAGGAGTGAGGTGTGAGG

Downstream 100 bases:

>100_bases
AATTCCCAATCCGTAAAATAGGGTTATGCCGAACTGCCAAGTTTCGTGACATCCTCCTAACACTGATACTATAGGCACAG
CGCAGGACCCATAGCTCCCC

Product: type IV pilus secretin PilQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 696; Mature: 696

Protein sequence:

>696_residues
MMNRRVAYGCALGLILSLPPLALESRVNEAAAQQLTSANPQRLSRITDIRLVPNGNRMQLEINTEGGARPQVFFTQQGQS
WIGDITNAQLSGSQGRYRQESPLPGVRFIEAWQLSNDSVRIEIAGVAAAPQGLLARRSPTQLVFDFEGLPSAPPAPLAAV
PPQPSSNPVAPGQPASLNRPQPVAPAPQPAAPAPASQPVAQNPAPPQTTQAAPPAPAVPAAPVISQVPPVGQLNQPQLPP
GSLPTESPFQGRAVAPPAGDIAVGTILPDPPTVDLGSNARISLTLKDAPVGDVLSLLVRRAGLNVVLNDVPPDLTISLDV
QDSPLQETFNFILRLKQLQAQRRGQTVFVGQNLPGVTGILVRNYRVNQAVATDLASRLEEVLNAVAPGAQFVVDERTNSI
TVIGNSRQQDIAAAQIAQLDVRRRQVLISLRAVDIRLDKNESLSVNLGGASGNFALGTLGDANFGGRPLNQPAGSSVSSI
GPAGPSGSITGIFNTLNRLQQSLALRVQSAIQNGTGKILTDPKVVVADGGSSRISIATSVPVNVETITIPQGENQPPVVT
QRLQREDAGVILDVSEVRIDDNGFVTLTIQPEISIPVPSQILGGGDFAGILLFNIDRRQLQASQLRLRDGQTFIIAGLIQ
DRDIVDVQKVPFLGDLPLLGALFRSQSVNNERNEVVFMLTPYIMDDNVAFGLPPNP

Sequences:

>Translated_696_residues
MMNRRVAYGCALGLILSLPPLALESRVNEAAAQQLTSANPQRLSRITDIRLVPNGNRMQLEINTEGGARPQVFFTQQGQS
WIGDITNAQLSGSQGRYRQESPLPGVRFIEAWQLSNDSVRIEIAGVAAAPQGLLARRSPTQLVFDFEGLPSAPPAPLAAV
PPQPSSNPVAPGQPASLNRPQPVAPAPQPAAPAPASQPVAQNPAPPQTTQAAPPAPAVPAAPVISQVPPVGQLNQPQLPP
GSLPTESPFQGRAVAPPAGDIAVGTILPDPPTVDLGSNARISLTLKDAPVGDVLSLLVRRAGLNVVLNDVPPDLTISLDV
QDSPLQETFNFILRLKQLQAQRRGQTVFVGQNLPGVTGILVRNYRVNQAVATDLASRLEEVLNAVAPGAQFVVDERTNSI
TVIGNSRQQDIAAAQIAQLDVRRRQVLISLRAVDIRLDKNESLSVNLGGASGNFALGTLGDANFGGRPLNQPAGSSVSSI
GPAGPSGSITGIFNTLNRLQQSLALRVQSAIQNGTGKILTDPKVVVADGGSSRISIATSVPVNVETITIPQGENQPPVVT
QRLQREDAGVILDVSEVRIDDNGFVTLTIQPEISIPVPSQILGGGDFAGILLFNIDRRQLQASQLRLRDGQTFIIAGLIQ
DRDIVDVQKVPFLGDLPLLGALFRSQSVNNERNEVVFMLTPYIMDDNVAFGLPPNP
>Mature_696_residues
MMNRRVAYGCALGLILSLPPLALESRVNEAAAQQLTSANPQRLSRITDIRLVPNGNRMQLEINTEGGARPQVFFTQQGQS
WIGDITNAQLSGSQGRYRQESPLPGVRFIEAWQLSNDSVRIEIAGVAAAPQGLLARRSPTQLVFDFEGLPSAPPAPLAAV
PPQPSSNPVAPGQPASLNRPQPVAPAPQPAAPAPASQPVAQNPAPPQTTQAAPPAPAVPAAPVISQVPPVGQLNQPQLPP
GSLPTESPFQGRAVAPPAGDIAVGTILPDPPTVDLGSNARISLTLKDAPVGDVLSLLVRRAGLNVVLNDVPPDLTISLDV
QDSPLQETFNFILRLKQLQAQRRGQTVFVGQNLPGVTGILVRNYRVNQAVATDLASRLEEVLNAVAPGAQFVVDERTNSI
TVIGNSRQQDIAAAQIAQLDVRRRQVLISLRAVDIRLDKNESLSVNLGGASGNFALGTLGDANFGGRPLNQPAGSSVSSI
GPAGPSGSITGIFNTLNRLQQSLALRVQSAIQNGTGKILTDPKVVVADGGSSRISIATSVPVNVETITIPQGENQPPVVT
QRLQREDAGVILDVSEVRIDDNGFVTLTIQPEISIPVPSQILGGGDFAGILLFNIDRRQLQASQLRLRDGQTFIIAGLIQ
DRDIVDVQKVPFLGDLPLLGALFRSQSVNNERNEVVFMLTPYIMDDNVAFGLPPNP

Specific function: Essential for the formation of pili. Involved in the biogenesis of type 4 fimbriae probably by serving as a "porthole" allowing passage of the fimbrae through the outer membrane [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI87082242, Length=361, Percent_Identity=28.5318559556787, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1789793, Length=428, Percent_Identity=24.7663551401869, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 73579; Mature: 73579

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNRRVAYGCALGLILSLPPLALESRVNEAAAQQLTSANPQRLSRITDIRLVPNGNRMQL
CCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCEEEEECCCCCEEEE
EINTEGGARPQVFFTQQGQSWIGDITNAQLSGSQGRYRQESPLPGVRFIEAWQLSNDSVR
EEECCCCCCCEEEEECCCCCHHCCCCCCEECCCCCCCCCCCCCCCCEEEEEEEECCCCEE
IEIAGVAAAPQGLLARRSPTQLVFDFEGLPSAPPAPLAAVPPQPSSNPVAPGQPASLNRP
EEEEEECCCCCHHHCCCCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCC
QPVAPAPQPAAPAPASQPVAQNPAPPQTTQAAPPAPAVPAAPVISQVPPVGQLNQPQLPP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCC
GSLPTESPFQGRAVAPPAGDIAVGTILPDPPTVDLGSNARISLTLKDAPVGDVLSLLVRR
CCCCCCCCCCCCEECCCCCCEEEEEECCCCCCEECCCCCEEEEEECCCCHHHHHHHHHHH
AGLNVVLNDVPPDLTISLDVQDSPLQETFNFILRLKQLQAQRRGQTVFVGQNLPGVTGIL
CCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEE
VRNYRVNQAVATDLASRLEEVLNAVAPGAQFVVDERTNSITVIGNSRQQDIAAAQIAQLD
EECEECHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHH
VRRRQVLISLRAVDIRLDKNESLSVNLGGASGNFALGTLGDANFGGRPLNQPAGSSVSSI
HHHHHEEEEEEEEEEEECCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHC
GPAGPSGSITGIFNTLNRLQQSLALRVQSAIQNGTGKILTDPKVVVADGGSSRISIATSV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCEEEEECCCCCEEEEEEEC
PVNVETITIPQGENQPPVVTQRLQREDAGVILDVSEVRIDDNGFVTLTIQPEISIPVPSQ
CCEEEEEEECCCCCCCCHHHHHHHHCCCCEEEEEHHEEECCCCEEEEEECCCCCCCCCHH
ILGGGDFAGILLFNIDRRQLQASQLRLRDGQTFIIAGLIQDRDIVDVQKVPFLGDLPLLG
HHCCCCEEEEEEEECCHHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHCCCCCCCCHHHH
ALFRSQSVNNERNEVVFMLTPYIMDDNVAFGLPPNP
HHHHHCCCCCCCCCEEEEEECEEECCCEEECCCCCC
>Mature Secondary Structure
MMNRRVAYGCALGLILSLPPLALESRVNEAAAQQLTSANPQRLSRITDIRLVPNGNRMQL
CCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCEEEEECCCCCEEEE
EINTEGGARPQVFFTQQGQSWIGDITNAQLSGSQGRYRQESPLPGVRFIEAWQLSNDSVR
EEECCCCCCCEEEEECCCCCHHCCCCCCEECCCCCCCCCCCCCCCCEEEEEEEECCCCEE
IEIAGVAAAPQGLLARRSPTQLVFDFEGLPSAPPAPLAAVPPQPSSNPVAPGQPASLNRP
EEEEEECCCCCHHHCCCCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCC
QPVAPAPQPAAPAPASQPVAQNPAPPQTTQAAPPAPAVPAAPVISQVPPVGQLNQPQLPP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCC
GSLPTESPFQGRAVAPPAGDIAVGTILPDPPTVDLGSNARISLTLKDAPVGDVLSLLVRR
CCCCCCCCCCCCEECCCCCCEEEEEECCCCCCEECCCCCEEEEEECCCCHHHHHHHHHHH
AGLNVVLNDVPPDLTISLDVQDSPLQETFNFILRLKQLQAQRRGQTVFVGQNLPGVTGIL
CCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEE
VRNYRVNQAVATDLASRLEEVLNAVAPGAQFVVDERTNSITVIGNSRQQDIAAAQIAQLD
EECEECHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHH
VRRRQVLISLRAVDIRLDKNESLSVNLGGASGNFALGTLGDANFGGRPLNQPAGSSVSSI
HHHHHEEEEEEEEEEEECCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHC
GPAGPSGSITGIFNTLNRLQQSLALRVQSAIQNGTGKILTDPKVVVADGGSSRISIATSV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCEEEEECCCCCEEEEEEEC
PVNVETITIPQGENQPPVVTQRLQREDAGVILDVSEVRIDDNGFVTLTIQPEISIPVPSQ
CCEEEEEEECCCCCCCCHHHHHHHHCCCCEEEEEHHEEECCCCEEEEEECCCCCCCCCHH
ILGGGDFAGILLFNIDRRQLQASQLRLRDGQTFIIAGLIQDRDIVDVQKVPFLGDLPLLG
HHCCCCEEEEEEEECCHHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHCCCCCCCCHHHH
ALFRSQSVNNERNEVVFMLTPYIMDDNVAFGLPPNP
HHHHHCCCCCCCCCEEEEEECEEECCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7901733; 10984043 [H]