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The map label for this gene is resE [H]

Identifier: 86606824

GI number: 86606824

Start: 2203378

End: 2204712

Strand: Reverse

Name: resE [H]

Synonym: CYA_2184

Alternate gene names: 86606824

Gene position: 2204712-2203378 (Counterclockwise)

Preceding gene: 86606825

Following gene: 86606823

Centisome position: 75.18

GC content: 63.37

Gene sequence:

>1335_bases
ATGTTCCAGGCAACGCGGCGGTGGTTGGCCCTCTGGTACACCGTGGTAACAGGGGTGTTTTTGTTGCTGTTTGCCGGCAG
CTTCTACTGGTATGTGCAGTCAACCCTGATCGAGCGGGTGGACGACACGCTGGGCCATGTGGTGGAAATTGTCGAGCGCT
CCCTGGTGGTGGACGAGAGCCTCTTGGATCCACAGCAGGCCCGCCAGAGCTTAGAGGCCAGCTTTCGGGATGATCCCAGC
ACCCTGGAGGACGACCACATCGACCTGGAGTGGTTTGATCCCCAGGGATCCCTCATCTGGTCCACGGTGCCCGGCGGCAT
CCCTGCCCCCCTGCTGACCGAGGGATCCCTGCACACCGCCCGCATCGCGCCTGGGTATTGGCTGCGCCAGTTCACCGAGC
CGATCCTGGCCGGTGGGAAGCTGCTGGGGTATTTGCGGGTCAGCCACCCCTGGTTTGAGGTGAGCAAGCCGACACGCCAG
CTCATTCGGGATCTCAGCCTCTGGGTAGTGGCCAGTTTGGCCTGTGTGGGGGGAATCGGCTGGCTGCTCTCCGGTTTGGC
CATGCAGCCCATCCGCCAGTCTTACCAGCAGCTCAAGCAATTTACCGCCGATGCCTCCCACGAGCTGCGCAGCCCCTTGG
CCAGCATTCAAACCACGGTACAGGTGGCTTTGGCCGATCCGCACCTGGACGCCGACACCCGCCAGCGCTGGCAGATGGTG
GAGCGGCTGTGTTTGCGGCTGGGCCGCCTGGTGGACGACCTGCTGTTTCTGGCCCGCCACGACAGCGGCATGGTGCCTTT
CCAGCCCCGCTGCTGTGCGCTGGATGCTCTGCTGCTGCAGGTGGTAGAGGAGTTGCAAGGGCTGGCCAACCAGAAAGGGA
TCCACCTCAAGCTGGACATTGTCACCCCCGACGAGGAAGCAGAGGGCTATCCCTTCGCCTTTTGGGGAGATGAAGACCTG
TTGGCCCGCCTGTTCACCAACCTGATCGAAAACGCCCTTCTCCACACTCCCTCTGGCGGCGAGGTGCAGGTGCGCCTTAG
GCAGCGGCTGCGCTCCGGATCCCCAGAACTGGTGCTTCAGGTGCAAGATAGCGGGCCGGGGATCCCACCCCAGGCGCTGC
CCCACCTGTTCGACCGTTTCTACCGGGTGGATCCGGCCCGCAGCGGGGATCCCAATCGGCGGTCGGGATCGGGTTTGGGG
CTGGCCATTGTCAAAAGCATCGCCGAGCAGCATCGGGGGCAGGTGCAGGTGGAGAGCGAGGTGGGGCAGGGATCCACCTT
TGAGGTGATTTTGCCCCAGCGACAATTGGAAACTTGCACTCCAGAAACCCTCTGA

Upstream 100 bases:

>100_bases
CGGCTGGACACCCTGCTGCAGGTGGAAGCGGAGATTTTATCGACCCTTCACCCTGAGCCTCGTGTCCACAGCTAACCCAT
CCCCTTCCCGCGCAACCCCC

Downstream 100 bases:

>100_bases
AAGTGCTCCAGAAAACAGACAATTCTTGGACAGTATGTTAAGTTCAAGCTAAAGTTCAATTGTTCTTTACTTAGAGAGCT
TTACTTTGGGGCTTTAGGTC

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MFQATRRWLALWYTVVTGVFLLLFAGSFYWYVQSTLIERVDDTLGHVVEIVERSLVVDESLLDPQQARQSLEASFRDDPS
TLEDDHIDLEWFDPQGSLIWSTVPGGIPAPLLTEGSLHTARIAPGYWLRQFTEPILAGGKLLGYLRVSHPWFEVSKPTRQ
LIRDLSLWVVASLACVGGIGWLLSGLAMQPIRQSYQQLKQFTADASHELRSPLASIQTTVQVALADPHLDADTRQRWQMV
ERLCLRLGRLVDDLLFLARHDSGMVPFQPRCCALDALLLQVVEELQGLANQKGIHLKLDIVTPDEEAEGYPFAFWGDEDL
LARLFTNLIENALLHTPSGGEVQVRLRQRLRSGSPELVLQVQDSGPGIPPQALPHLFDRFYRVDPARSGDPNRRSGSGLG
LAIVKSIAEQHRGQVQVESEVGQGSTFEVILPQRQLETCTPETL

Sequences:

>Translated_444_residues
MFQATRRWLALWYTVVTGVFLLLFAGSFYWYVQSTLIERVDDTLGHVVEIVERSLVVDESLLDPQQARQSLEASFRDDPS
TLEDDHIDLEWFDPQGSLIWSTVPGGIPAPLLTEGSLHTARIAPGYWLRQFTEPILAGGKLLGYLRVSHPWFEVSKPTRQ
LIRDLSLWVVASLACVGGIGWLLSGLAMQPIRQSYQQLKQFTADASHELRSPLASIQTTVQVALADPHLDADTRQRWQMV
ERLCLRLGRLVDDLLFLARHDSGMVPFQPRCCALDALLLQVVEELQGLANQKGIHLKLDIVTPDEEAEGYPFAFWGDEDL
LARLFTNLIENALLHTPSGGEVQVRLRQRLRSGSPELVLQVQDSGPGIPPQALPHLFDRFYRVDPARSGDPNRRSGSGLG
LAIVKSIAEQHRGQVQVESEVGQGSTFEVILPQRQLETCTPETL
>Mature_444_residues
MFQATRRWLALWYTVVTGVFLLLFAGSFYWYVQSTLIERVDDTLGHVVEIVERSLVVDESLLDPQQARQSLEASFRDDPS
TLEDDHIDLEWFDPQGSLIWSTVPGGIPAPLLTEGSLHTARIAPGYWLRQFTEPILAGGKLLGYLRVSHPWFEVSKPTRQ
LIRDLSLWVVASLACVGGIGWLLSGLAMQPIRQSYQQLKQFTADASHELRSPLASIQTTVQVALADPHLDADTRQRWQMV
ERLCLRLGRLVDDLLFLARHDSGMVPFQPRCCALDALLLQVVEELQGLANQKGIHLKLDIVTPDEEAEGYPFAFWGDEDL
LARLFTNLIENALLHTPSGGEVQVRLRQRLRSGSPELVLQVQDSGPGIPPQALPHLFDRFYRVDPARSGDPNRRSGSGLG
LAIVKSIAEQHRGQVQVESEVGQGSTFEVILPQRQLETCTPETL

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786783, Length=248, Percent_Identity=32.6612903225806, Blast_Score=125, Evalue=8e-30,
Organism=Escherichia coli, GI1786600, Length=237, Percent_Identity=34.5991561181435, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788393, Length=243, Percent_Identity=34.5679012345679, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI48994928, Length=232, Percent_Identity=30.6034482758621, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788279, Length=245, Percent_Identity=30.2040816326531, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1789149, Length=243, Percent_Identity=27.5720164609054, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI145693157, Length=251, Percent_Identity=27.8884462151394, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1789403, Length=219, Percent_Identity=33.7899543378995, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790346, Length=234, Percent_Identity=27.3504273504274, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790551, Length=218, Percent_Identity=30.2752293577982, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI87081816, Length=258, Percent_Identity=30.6201550387597, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1790436, Length=244, Percent_Identity=28.2786885245902, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788713, Length=239, Percent_Identity=24.6861924686192, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787374, Length=243, Percent_Identity=25.9259259259259, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787894, Length=234, Percent_Identity=29.4871794871795, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788549, Length=235, Percent_Identity=25.9574468085106, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1786912, Length=239, Percent_Identity=28.4518828451883, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1790861, Length=328, Percent_Identity=25.9146341463415, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1790567, Length=122, Percent_Identity=40.1639344262295, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49690; Mature: 49690

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQATRRWLALWYTVVTGVFLLLFAGSFYWYVQSTLIERVDDTLGHVVEIVERSLVVDES
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLDPQQARQSLEASFRDDPSTLEDDHIDLEWFDPQGSLIWSTVPGGIPAPLLTEGSLHTA
HCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCEE
RIAPGYWLRQFTEPILAGGKLLGYLRVSHPWFEVSKPTRQLIRDLSLWVVASLACVGGIG
EECCHHHHHHHHHHHHHCCHHEEEEEECCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
WLLSGLAMQPIRQSYQQLKQFTADASHELRSPLASIQTTVQVALADPHLDADTRQRWQMV
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHH
ERLCLRLGRLVDDLLFLARHDSGMVPFQPRCCALDALLLQVVEELQGLANQKGIHLKLDI
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
VTPDEEAEGYPFAFWGDEDLLARLFTNLIENALLHTPSGGEVQVRLRQRLRSGSPELVLQ
ECCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHEECCCCCEEEHHHHHHHHCCCCEEEEE
VQDSGPGIPPQALPHLFDRFYRVDPARSGDPNRRSGSGLGLAIVKSIAEQHRGQVQVESE
ECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECC
VGQGSTFEVILPQRQLETCTPETL
CCCCCEEEEECCHHHHHCCCCCCC
>Mature Secondary Structure
MFQATRRWLALWYTVVTGVFLLLFAGSFYWYVQSTLIERVDDTLGHVVEIVERSLVVDES
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLDPQQARQSLEASFRDDPSTLEDDHIDLEWFDPQGSLIWSTVPGGIPAPLLTEGSLHTA
HCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCEE
RIAPGYWLRQFTEPILAGGKLLGYLRVSHPWFEVSKPTRQLIRDLSLWVVASLACVGGIG
EECCHHHHHHHHHHHHHCCHHEEEEEECCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
WLLSGLAMQPIRQSYQQLKQFTADASHELRSPLASIQTTVQVALADPHLDADTRQRWQMV
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHH
ERLCLRLGRLVDDLLFLARHDSGMVPFQPRCCALDALLLQVVEELQGLANQKGIHLKLDI
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
VTPDEEAEGYPFAFWGDEDLLARLFTNLIENALLHTPSGGEVQVRLRQRLRSGSPELVLQ
ECCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHEECCCCCEEEHHHHHHHHCCCCEEEEE
VQDSGPGIPPQALPHLFDRFYRVDPARSGDPNRRSGSGLGLAIVKSIAEQHRGQVQVESE
ECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECC
VGQGSTFEVILPQRQLETCTPETL
CCCCCEEEEECCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]