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The map label for this gene is gpsA

Identifier: 86605198

GI number: 86605198

Start: 498264

End: 499196

Strand: Reverse

Name: gpsA

Synonym: CYA_0480

Alternate gene names: 86605198

Gene position: 499196-498264 (Counterclockwise)

Preceding gene: 86605201

Following gene: 86605197

Centisome position: 17.02

GC content: 62.38

Gene sequence:

>933_bases
ATGAAAACTAACACAACATCCCCCCAGAAGATCGCCATTCTAGGGGCGGGAGCCTGGGGAAGTACGCTGGCTCTGCTGGC
CCAGGCCCAGGGGCACCGAGTGCAGGTTTGGGACCGGCGCAAAGATCTGGATCTCAAAGAGGTGCTCCAGGGATCCCAAA
TCCTCATCTCGGCAGTCTCGATGGCAGGGGTGCGCCCCGTGGCCGAGGTTGTGCGCCAGGTGGGGATCCCACCGCAGGTT
ATTTTGGTCTCAGCCACTAAGGGACTGGATCCGCTCCAACTTTTGACTCCTGCCCAAATCTGGGGGGCTGCCTTCCCCAA
CCAGCCGTTGGTGGTGCTCTCCGGGCCTAACCTTTCCGCCGAGATCCGCCAGGGTTTGCCGGCAGCAGCAGTGGTAGCCA
GCCGGGATCTCTGGGCAGCCGTGCAGGTGCAGCATGCCCTGGCTTCAGAGCGCTTTCGCCTCTACACCAGCAGCGATCCG
CTGGGGGTGGAGCTGGGAGGCATCCTGAAAAATGTTATCGCCATCGCCGTGGGGGTGTGTGATGCGCTGCACCTGGGCAC
CAATGCTCGGGCTGCCCTGGTTACCCGCGGCTTGGCAGAGATGATCCGGGTGGGATCCCGCTTAGGGGCGCGGCCTGAGA
CCTTCAACGGCCTCTCAGGCCTGGGGGATCTGCTGGCCACCTGTCACAGTCCTCTGAGCCGCAACTACCAGGTGGGCTAC
GGGTTGGGCCAAGGTAGGCCTTTGTCCCAGGTTCTGGCTGAAATCGAGGGCACTGCCGAAGGAGTTTACACCGCTCCTGT
CGTGGTCAAGATCGCCGCCCAACACAACATCCGGGTGCCTATCACCCAGGAGGTGCATCGGTTGTTGCAAGGACAGACCA
CCCCCACTGCTGCCCTGGCCAGGCTGATGGAGCGACAACTCACCTCGGAATAA

Upstream 100 bases:

>100_bases
AACCCATGATTTGGTATCCAACCATACTAACCTTTGTCGCTCTCTTGCTAACGGGGAGTTTAAGGCATCCTGGGAGAGAA
GCTGCGGCTGCAAAGGTCAG

Downstream 100 bases:

>100_bases
GACCCTCACCCCCCTGCCCCTCTCCCTCTGGGAGAGGGGAGTTAGGGATAAACGTTGCATTGCTATTTGAAATGACCATA
GCCGCAAATCCGCGGATGAG

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MKTNTTSPQKIAILGAGAWGSTLALLAQAQGHRVQVWDRRKDLDLKEVLQGSQILISAVSMAGVRPVAEVVRQVGIPPQV
ILVSATKGLDPLQLLTPAQIWGAAFPNQPLVVLSGPNLSAEIRQGLPAAAVVASRDLWAAVQVQHALASERFRLYTSSDP
LGVELGGILKNVIAIAVGVCDALHLGTNARAALVTRGLAEMIRVGSRLGARPETFNGLSGLGDLLATCHSPLSRNYQVGY
GLGQGRPLSQVLAEIEGTAEGVYTAPVVVKIAAQHNIRVPITQEVHRLLQGQTTPTAALARLMERQLTSE

Sequences:

>Translated_310_residues
MKTNTTSPQKIAILGAGAWGSTLALLAQAQGHRVQVWDRRKDLDLKEVLQGSQILISAVSMAGVRPVAEVVRQVGIPPQV
ILVSATKGLDPLQLLTPAQIWGAAFPNQPLVVLSGPNLSAEIRQGLPAAAVVASRDLWAAVQVQHALASERFRLYTSSDP
LGVELGGILKNVIAIAVGVCDALHLGTNARAALVTRGLAEMIRVGSRLGARPETFNGLSGLGDLLATCHSPLSRNYQVGY
GLGQGRPLSQVLAEIEGTAEGVYTAPVVVKIAAQHNIRVPITQEVHRLLQGQTTPTAALARLMERQLTSE
>Mature_310_residues
MKTNTTSPQKIAILGAGAWGSTLALLAQAQGHRVQVWDRRKDLDLKEVLQGSQILISAVSMAGVRPVAEVVRQVGIPPQV
ILVSATKGLDPLQLLTPAQIWGAAFPNQPLVVLSGPNLSAEIRQGLPAAAVVASRDLWAAVQVQHALASERFRLYTSSDP
LGVELGGILKNVIAIAVGVCDALHLGTNARAALVTRGLAEMIRVGSRLGARPETFNGLSGLGDLLATCHSPLSRNYQVGY
GLGQGRPLSQVLAEIEGTAEGVYTAPVVVKIAAQHNIRVPITQEVHRLLQGQTTPTAALARLMERQLTSE

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=295, Percent_Identity=24.0677966101695, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI24307999, Length=331, Percent_Identity=23.2628398791541, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1790037, Length=323, Percent_Identity=36.5325077399381, Blast_Score=170, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI32564399, Length=344, Percent_Identity=24.7093023255814, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI32564403, Length=350, Percent_Identity=24.2857142857143, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI193210136, Length=348, Percent_Identity=24.1379310344828, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193210134, Length=304, Percent_Identity=24.6710526315789, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17507425, Length=341, Percent_Identity=25.2199413489736, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17136202, Length=334, Percent_Identity=23.3532934131737, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI17136204, Length=334, Percent_Identity=23.3532934131737, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI17136200, Length=334, Percent_Identity=23.3532934131737, Blast_Score=78, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_SYNJA (Q2JX02)

Other databases:

- EMBL:   CP000239
- RefSeq:   YP_473961.1
- ProteinModelPortal:   Q2JX02
- SMR:   Q2JX02
- STRING:   Q2JX02
- GeneID:   3897491
- GenomeReviews:   CP000239_GR
- KEGG:   cya:CYA_0480
- TIGR:   CYA_0480
- eggNOG:   COG0240
- HOGENOM:   HBG586392
- OMA:   NYRVGYG
- ProtClustDB:   PRK14619
- BioCyc:   SSP321327:CYA_0480-MONOMER
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 32751; Mature: 32751

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 170-170 BINDING 87-87 BINDING 87-87 BINDING 119-119 BINDING 234-234 BINDING 260-260

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTNTTSPQKIAILGAGAWGSTLALLAQAQGHRVQVWDRRKDLDLKEVLQGSQILISAVS
CCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHCCCHHHHHHHH
MAGVRPVAEVVRQVGIPPQVILVSATKGLDPLQLLTPAQIWGAAFPNQPLVVLSGPNLSA
HHCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHCHHHHHHCCCCCCCEEEEECCCCHH
EIRQGLPAAAVVASRDLWAAVQVQHALASERFRLYTSSDPLGVELGGILKNVIAIAVGVC
HHHCCCCHHHHHHCCHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHH
DALHLGTNARAALVTRGLAEMIRVGSRLGARPETFNGLSGLGDLLATCHSPLSRNYQVGY
HHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEE
GLGQGRPLSQVLAEIEGTAEGVYTAPVVVKIAAQHNIRVPITQEVHRLLQGQTTPTAALA
CCCCCCCHHHHHHHHCCCCCCEEECCEEEEEECCCCCCCCCHHHHHHHHCCCCCHHHHHH
RLMERQLTSE
HHHHHHHCCC
>Mature Secondary Structure
MKTNTTSPQKIAILGAGAWGSTLALLAQAQGHRVQVWDRRKDLDLKEVLQGSQILISAVS
CCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHCCCHHHHHHHH
MAGVRPVAEVVRQVGIPPQVILVSATKGLDPLQLLTPAQIWGAAFPNQPLVVLSGPNLSA
HHCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHCHHHHHHCCCCCCCEEEEECCCCHH
EIRQGLPAAAVVASRDLWAAVQVQHALASERFRLYTSSDPLGVELGGILKNVIAIAVGVC
HHHCCCCHHHHHHCCHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHH
DALHLGTNARAALVTRGLAEMIRVGSRLGARPETFNGLSGLGDLLATCHSPLSRNYQVGY
HHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEE
GLGQGRPLSQVLAEIEGTAEGVYTAPVVVKIAAQHNIRVPITQEVHRLLQGQTTPTAALA
CCCCCCCHHHHHHHHCCCCCCEEECCEEEEEECCCCCCCCCHHHHHHHHCCCCCHHHHHH
RLMERQLTSE
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA