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The map label for this gene is coaX

Identifier: 86605057

GI number: 86605057

Start: 356210

End: 356944

Strand: Reverse

Name: coaX

Synonym: CYA_0337

Alternate gene names: 86605057

Gene position: 356944-356210 (Counterclockwise)

Preceding gene: 86605058

Following gene: 86605056

Centisome position: 12.17

GC content: 68.44

Gene sequence:

>735_bases
ATGAGTTCTGAGGCAGAGCGGTGGCTGGCCGCCGTGGTGGGCAACACCCACGTGCGCTGGGGCTGGTTTGCTGGCGAGAG
CTTGGTGAAGGTGGAGCAGTTTCCCGCCCACCAACCCCTATCCTGGCCAGAAGAGACGGAGCTGTGGCTAGCTGCCGTTG
GCTCTGCCCCTTTGCCGCCCCGATCCCCCTGGGTGCATTGCCTTGAGCTCTCCCAGGTGCCGCTGCGGGATCCCTACCCA
AGCCTGGGGCTGGATCGGGCACTAGCTCTGTGGGCCGCCGGGATCCGCTACGGCTGGCCCTGCTTGGTCATCGACGCCGG
CACCGCCTTGACCCTGACGGGAGCTGACGCCGAGGGATCCCTGGTGGGAGGAGCGATCCTGCCCGGCCTGGGGTTGCAGG
CGCAGGCGCTGGCCGACCACACCGCCCGGCTGCCCAAAGTGGAGTGGGATCCCGGCGCTCCCATACCCCCCCGCTGGGCC
AGGAACACTGGGGCCGCCATCCGCAGCGGCATTCTTCATACCCTGCTGGCCGGCTTGCGGGATTTTCTGGCCGACTGGCG
CCGCCGCTTTCCCCAAGGCCCGCTGCTAGTAACCGGCGGCGATGGCGAGCTACTCTACCCCCACCTGCGGCCCCTTGACG
CAGAGCTGCGCTGGGATCCCCACCTGGTGTTGCGGGGGATTGCCGGCTGCCGTCAGTTGCACCGCGTCGTCCGCAAGCCT
TCTGGTGCAGAATAG

Upstream 100 bases:

>100_bases
GCTCTGACGACGGCCTGGCAGCTCTCCACCGCCAAGCAATTGGCCGGGATCCCTGCCGATCAGCCGGTGGAGCTGTTTCG
CGTGGAGGCGGAGCTGTTGC

Downstream 100 bases:

>100_bases
AAGACAGTCTCTCCCAGCCGCCTGCGAGCGGGCAGCTTCTTGCTCAGGGATCCCATGGCCAACGGCAACTCCTTCGGCGT
CTTGTTTTGCGTCACCACCT

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MSSEAERWLAAVVGNTHVRWGWFAGESLVKVEQFPAHQPLSWPEETELWLAAVGSAPLPPRSPWVHCLELSQVPLRDPYP
SLGLDRALALWAAGIRYGWPCLVIDAGTALTLTGADAEGSLVGGAILPGLGLQAQALADHTARLPKVEWDPGAPIPPRWA
RNTGAAIRSGILHTLLAGLRDFLADWRRRFPQGPLLVTGGDGELLYPHLRPLDAELRWDPHLVLRGIAGCRQLHRVVRKP
SGAE

Sequences:

>Translated_244_residues
MSSEAERWLAAVVGNTHVRWGWFAGESLVKVEQFPAHQPLSWPEETELWLAAVGSAPLPPRSPWVHCLELSQVPLRDPYP
SLGLDRALALWAAGIRYGWPCLVIDAGTALTLTGADAEGSLVGGAILPGLGLQAQALADHTARLPKVEWDPGAPIPPRWA
RNTGAAIRSGILHTLLAGLRDFLADWRRRFPQGPLLVTGGDGELLYPHLRPLDAELRWDPHLVLRGIAGCRQLHRVVRKP
SGAE
>Mature_243_residues
SSEAERWLAAVVGNTHVRWGWFAGESLVKVEQFPAHQPLSWPEETELWLAAVGSAPLPPRSPWVHCLELSQVPLRDPYPS
LGLDRALALWAAGIRYGWPCLVIDAGTALTLTGADAEGSLVGGAILPGLGLQAQALADHTARLPKVEWDPGAPIPPRWAR
NTGAAIRSGILHTLLAGLRDFLADWRRRFPQGPLLVTGGDGELLYPHLRPLDAELRWDPHLVLRGIAGCRQLHRVVRKPS
GAE

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_SYNJA (Q2JXC9)

Other databases:

- EMBL:   CP000239
- RefSeq:   YP_473820.1
- ProteinModelPortal:   Q2JXC9
- SMR:   Q2JXC9
- STRING:   Q2JXC9
- GeneID:   3898005
- GenomeReviews:   CP000239_GR
- KEGG:   cya:CYA_0337
- TIGR:   CYA_0337
- eggNOG:   COG1521
- HOGENOM:   HBG634537
- OMA:   WPEETEL
- ProtClustDB:   PRK13331
- BioCyc:   SSP321327:CYA_0337-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 26573; Mature: 26442

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: ACT_SITE 85-85 BINDING 79-79 BINDING 108-108 BINDING 163-163

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSEAERWLAAVVGNTHVRWGWFAGESLVKVEQFPAHQPLSWPEETELWLAAVGSAPLPP
CCCHHHHHHHHHHCCCEEEEEEECCCCCEEHHHCCCCCCCCCCCHHCEEEEEECCCCCCC
RSPWVHCLELSQVPLRDPYPSLGLDRALALWAAGIRYGWPCLVIDAGTALTLTGADAEGS
CCCHHEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCEEEEECCCCCCC
LVGGAILPGLGLQAQALADHTARLPKVEWDPGAPIPPRWARNTGAAIRSGILHTLLAGLR
EECCHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
DFLADWRRRFPQGPLLVTGGDGELLYPHLRPLDAELRWDPHLVLRGIAGCRQLHRVVRKP
HHHHHHHHHCCCCCEEEECCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
SGAE
CCCC
>Mature Secondary Structure 
SSEAERWLAAVVGNTHVRWGWFAGESLVKVEQFPAHQPLSWPEETELWLAAVGSAPLPP
CCHHHHHHHHHHCCCEEEEEEECCCCCEEHHHCCCCCCCCCCCHHCEEEEEECCCCCCC
RSPWVHCLELSQVPLRDPYPSLGLDRALALWAAGIRYGWPCLVIDAGTALTLTGADAEGS
CCCHHEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCEEEEECCCCCCC
LVGGAILPGLGLQAQALADHTARLPKVEWDPGAPIPPRWARNTGAAIRSGILHTLLAGLR
EECCHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
DFLADWRRRFPQGPLLVTGGDGELLYPHLRPLDAELRWDPHLVLRGIAGCRQLHRVVRKP
HHHHHHHHHCCCCCEEEECCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
SGAE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA