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The map label for this gene is aroC

Identifier: 86605056

GI number: 86605056

Start: 355019

End: 356155

Strand: Reverse

Name: aroC

Synonym: CYA_0336

Alternate gene names: 86605056

Gene position: 356155-355019 (Counterclockwise)

Preceding gene: 86605057

Following gene: 86605055

Centisome position: 12.14

GC content: 67.99

Gene sequence:

>1137_bases
ATGGCCAACGGCAACTCCTTCGGCGTCTTGTTTTGCGTCACCACCTACGGCGAGTCCCACGGGGGGGCGGTGGGGGTGGT
GGTGGACGGCTGCCCGCCGCGGCTGCCCTTGAGCGAGGCCGACATCCAGGCGGAGCTGGATCGGCGCCGTCCCGGCCAGA
GCCACATCACCACGCCGCGCCAGGAGGCGGATCGCTGCCAGATCCTCTCCGGGGTTTTCCAAGGCTTTACCCTCGGCACC
CCCATCCACATCCTGGTGCGCAACCAGGACGCCCGCCCCCAGGATTACAGCGAGATGGCCACCACCTTCCGCCCTTCCCA
TGCCGATGCCACCTACCAGGCCAAGTACGGCATCCGCAACTGGCAGGGGGGAGGGCGGGCCTCGGCGCGGGAGACCATTG
GCCGGGTGGCCGCCGGGGCCATCGCCAAGAAGATCCTGCGCCTGGCAGCAGGGGTAGAGATCCTGGCCTATGTGCAGCGG
GTCCAAGACGTAGAGGCCCAGGTGGATCCCAGCTCCGTGACGGCGGAGCAGGTGGAAGCCAACATCGTCCGCTGCCCCGA
TCCAGCCGCGGCGGCGGCGATGATTGAAAAAATTGAAGCAGCGGCGCGGGAAGGAGATTCTCTCGGGGGAGTGGTGGAAT
GTGTGGCCCGCAATGTGCCCCGCGGGCTGGGCTGCCCGGTGTTCGACAAATTGGAGGCCGACCTGGCCAAGGCGGTGATG
TCGCTGCCGGCCAGCAAGGGGTTTGAGATCGGTTCGGGGTTTGCCGGCACCTACCTGACGGGCAAGCAGCACAACGACGA
GTTCTACATGACCCCCAGCGGCTGGCGCACCCGCAGCAACCGCTCCGGCGGCATCCAGGGGGGCATCAGCAACGGGGAAG
ACATCGTCCTGCGGGTGGCCTTCAAGCCCACCGCCACCATTCGCCAGCCCCAAAGCACCGTCACCCTCGACGGGCAGGAG
ACGGTTTTGGCGGCGCGGGGGCGCCACGATCCCTGCGTGCTGCCGCGGGCGGTGCCGATGGTGGAGGCGATGGTGGCTTT
GGTGCTCTGTGACCATCTGCTGCGCCACCACGCCCAGTGCCGATCCCTGGCCTTGCCAGAGGTGCCCATTCCCGCCGTTC
CCCTGCCCCACAGCTAG

Upstream 100 bases:

>100_bases
CCGTCAGTTGCACCGCGTCGTCCGCAAGCCTTCTGGTGCAGAATAGAAGACAGTCTCTCCCAGCCGCCTGCGAGCGGGCA
GCTTCTTGCTCAGGGATCCC

Downstream 100 bases:

>100_bases
CGGCAGCCGGTCGGAGTCCTTGTATCCTAAGAAAGAGGCGGGATCCCTGTTCATGGCCAAGGCCAAAACCGTCTGGGAGT
GCAGCCAGTGCGGCGAGCGC

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MANGNSFGVLFCVTTYGESHGGAVGVVVDGCPPRLPLSEADIQAELDRRRPGQSHITTPRQEADRCQILSGVFQGFTLGT
PIHILVRNQDARPQDYSEMATTFRPSHADATYQAKYGIRNWQGGGRASARETIGRVAAGAIAKKILRLAAGVEILAYVQR
VQDVEAQVDPSSVTAEQVEANIVRCPDPAAAAAMIEKIEAAAREGDSLGGVVECVARNVPRGLGCPVFDKLEADLAKAVM
SLPASKGFEIGSGFAGTYLTGKQHNDEFYMTPSGWRTRSNRSGGIQGGISNGEDIVLRVAFKPTATIRQPQSTVTLDGQE
TVLAARGRHDPCVLPRAVPMVEAMVALVLCDHLLRHHAQCRSLALPEVPIPAVPLPHS

Sequences:

>Translated_378_residues
MANGNSFGVLFCVTTYGESHGGAVGVVVDGCPPRLPLSEADIQAELDRRRPGQSHITTPRQEADRCQILSGVFQGFTLGT
PIHILVRNQDARPQDYSEMATTFRPSHADATYQAKYGIRNWQGGGRASARETIGRVAAGAIAKKILRLAAGVEILAYVQR
VQDVEAQVDPSSVTAEQVEANIVRCPDPAAAAAMIEKIEAAAREGDSLGGVVECVARNVPRGLGCPVFDKLEADLAKAVM
SLPASKGFEIGSGFAGTYLTGKQHNDEFYMTPSGWRTRSNRSGGIQGGISNGEDIVLRVAFKPTATIRQPQSTVTLDGQE
TVLAARGRHDPCVLPRAVPMVEAMVALVLCDHLLRHHAQCRSLALPEVPIPAVPLPHS
>Mature_377_residues
ANGNSFGVLFCVTTYGESHGGAVGVVVDGCPPRLPLSEADIQAELDRRRPGQSHITTPRQEADRCQILSGVFQGFTLGTP
IHILVRNQDARPQDYSEMATTFRPSHADATYQAKYGIRNWQGGGRASARETIGRVAAGAIAKKILRLAAGVEILAYVQRV
QDVEAQVDPSSVTAEQVEANIVRCPDPAAAAAMIEKIEAAAREGDSLGGVVECVARNVPRGLGCPVFDKLEADLAKAVMS
LPASKGFEIGSGFAGTYLTGKQHNDEFYMTPSGWRTRSNRSGGIQGGISNGEDIVLRVAFKPTATIRQPQSTVTLDGQET
VLAARGRHDPCVLPRAVPMVEAMVALVLCDHLLRHHAQCRSLALPEVPIPAVPLPHS

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=356, Percent_Identity=53.0898876404494, Blast_Score=340, Evalue=1e-94,
Organism=Saccharomyces cerevisiae, GI6321290, Length=367, Percent_Identity=55.5858310626703, Blast_Score=403, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_SYNJA (Q2JXD0)

Other databases:

- EMBL:   CP000239
- RefSeq:   YP_473819.1
- HSSP:   P63611
- ProteinModelPortal:   Q2JXD0
- SMR:   Q2JXD0
- STRING:   Q2JXD0
- GeneID:   3898004
- GenomeReviews:   CP000239_GR
- KEGG:   cya:CYA_0336
- TIGR:   CYA_0336
- eggNOG:   COG0082
- HOGENOM:   HBG292336
- OMA:   TATIGKE
- ProtClustDB:   PRK05382
- BioCyc:   SSP321327:CYA_0336-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 40328; Mature: 40197

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANGNSFGVLFCVTTYGESHGGAVGVVVDGCPPRLPLSEADIQAELDRRRPGQSHITTPR
CCCCCCEEEEEEEEECCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCH
QEADRCQILSGVFQGFTLGTPIHILVRNQDARPQDYSEMATTFRPSHADATYQAKYGIRN
HHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHCCCCCCCCEEEECCCCCC
WQGGGRASARETIGRVAAGAIAKKILRLAAGVEILAYVQRVQDVEAQVDPSSVTAEQVEA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHC
NIVRCPDPAAAAAMIEKIEAAAREGDSLGGVVECVARNVPRGLGCPVFDKLEADLAKAVM
CEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
SLPASKGFEIGSGFAGTYLTGKQHNDEFYMTPSGWRTRSNRSGGIQGGISNGEDIVLRVA
HCCCCCCCCCCCCCCCCEECCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEE
FKPTATIRQPQSTVTLDGQETVLAARGRHDPCVLPRAVPMVEAMVALVLCDHLLRHHAQC
ECCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RSLALPEVPIPAVPLPHS
HHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ANGNSFGVLFCVTTYGESHGGAVGVVVDGCPPRLPLSEADIQAELDRRRPGQSHITTPR
CCCCCEEEEEEEEECCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCH
QEADRCQILSGVFQGFTLGTPIHILVRNQDARPQDYSEMATTFRPSHADATYQAKYGIRN
HHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHCCCCCCCCEEEECCCCCC
WQGGGRASARETIGRVAAGAIAKKILRLAAGVEILAYVQRVQDVEAQVDPSSVTAEQVEA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHC
NIVRCPDPAAAAAMIEKIEAAAREGDSLGGVVECVARNVPRGLGCPVFDKLEADLAKAVM
CEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
SLPASKGFEIGSGFAGTYLTGKQHNDEFYMTPSGWRTRSNRSGGIQGGISNGEDIVLRVA
HCCCCCCCCCCCCCCCCEECCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEE
FKPTATIRQPQSTVTLDGQETVLAARGRHDPCVLPRAVPMVEAMVALVLCDHLLRHHAQC
ECCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RSLALPEVPIPAVPLPHS
HHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA