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The map label for this gene is 86361275

Identifier: 86361275

GI number: 86361275

Start: 610533

End: 611819

Strand: Direct

Name: 86361275

Synonym: RHE_PF00546

Alternate gene names: NA

Gene position: 610533-611819 (Clockwise)

Preceding gene: 86361274

Following gene: 86361281

Centisome position: 95.02

GC content: 61.38

Gene sequence:

>1287_bases
ATGTCGTCCACCGAACATCTCGTCACCCGCCGAACTCTTCTTGCCAGCGCCGCCGCTGCCGGCGCGTTGATCATCATGCC
ACAACAAGTGGCGTTCGCCAAAGAAGGCGACGAACGTATCCGCCGCTTCAGCTTCAAGGCCAGCGAAGAGCAGCTCGGCG
ATCTGCGCCGCCGCATCGAGGCAACGCGCTTTCCCGAACCTGAGCTCGTCGCCGACAGCTCGCAAGGCGTCCAGTCCGCA
ACAATCGAAAAGCTGGCGAAATATTGGGCGACGAACTACGATTGGAGAAAGATCGAAGCCAAGCTCAACGAATTGCCGCA
GTTCATCACGGAGATCGACGGCGTCGACATCCACTTCATCCATGTCAAAGCCAAGCATGACGGCGCCCTCCCGATCATCG
TGACGCACGGATGGCCGGGCTCGATCATCGAGCAGATGAAGATCATCGGACCGCTGACGGATCCGACCGCGCATGGCGGC
TCGGCATCCGACGCCTTCGACGTCGTCATCCCTTCTATTCCGGGGTACGGCTTCTCCGGCAAGCCGACCGAAAAGGGTTG
GGATCCGATCCGGATCGCCCATGCGTGGATCGAGCTGATGAAACGTCTTGGCTACGCCAGATACGTGGCCCAGGGCGGCG
ACTGGGGCGATGCGGTGACCGAACAAATGGCGCTGATCGCCCCGCCCGAACTCCTCGGCATCCACGTCAACATGCCGGCA
ACCGTACCGGAGGACATCGCCACGGCCCTGCAGCCTGGCGGCAAGAAGCCGGCGGGATTGTCGCCGGACGAATCCCATGC
CTACGATCAGCTGGCCGACTTCTACGCACACGGCCTCGGCTATGCGATCGAGATGGCGAACCGGCCCCAGACGCTCGTCG
GCATTACGGATTCTCCCGTCGGCCTCGCTGCCTGGATGATCGACCACGACATCCGCAGCTATGAGCTGATCGCTCGTATC
TTTGACGGGAGGACGGAAGGTCTCAGCCGAGACGATATTCTCGATAACATCACCCTCTACTGGCTCACGAACACGGCTGT
TTCGTCGGCGCGGCTGTATTGGGAGAACAAGCTCGCCTTCTTCCAGCCGAAGAACGTCAAGATCCCGGTCGCCGTCAGCG
TCTTCCCCGACGAAATCTACGCCGCGCCGCGAAGCTGGACCGAGAAGGCCTATGCGAACCTGATCCACTTCAACAGGCTC
GACAAGGGCGGCCATTTCGCCGCCTGGGAGCAGACCCAGCTGTTCTGCGAGGAAATGCGAACGTCGTTCCGCACGGTTCG
GAGCTAG

Upstream 100 bases:

>100_bases
CACAAATCCAAAGGTATCGGCGACACCTTGGTGCAATAGATCCTCGCTTCGTCAAGTGTGAAGCTCTCCTGCGTCCAAAC
ACCCATCACAGGAGAACGCC

Downstream 100 bases:

>100_bases
AACGGCCCATCGTTTCTGAATGGAGGCCGGACTCAACCGTGGTTGAGTTCGGCCATCGCAGGAGCCGGCGGCGCGATGAT
GCCTTTCAGGATCTGATGAG

Product: putative epoxide hydrolase protein

Products: NA

Alternate protein names: Epoxide hydratase [H]

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MSSTEHLVTRRTLLASAAAAGALIIMPQQVAFAKEGDERIRRFSFKASEEQLGDLRRRIEATRFPEPELVADSSQGVQSA
TIEKLAKYWATNYDWRKIEAKLNELPQFITEIDGVDIHFIHVKAKHDGALPIIVTHGWPGSIIEQMKIIGPLTDPTAHGG
SASDAFDVVIPSIPGYGFSGKPTEKGWDPIRIAHAWIELMKRLGYARYVAQGGDWGDAVTEQMALIAPPELLGIHVNMPA
TVPEDIATALQPGGKKPAGLSPDESHAYDQLADFYAHGLGYAIEMANRPQTLVGITDSPVGLAAWMIDHDIRSYELIARI
FDGRTEGLSRDDILDNITLYWLTNTAVSSARLYWENKLAFFQPKNVKIPVAVSVFPDEIYAAPRSWTEKAYANLIHFNRL
DKGGHFAAWEQTQLFCEEMRTSFRTVRS

Sequences:

>Translated_428_residues
MSSTEHLVTRRTLLASAAAAGALIIMPQQVAFAKEGDERIRRFSFKASEEQLGDLRRRIEATRFPEPELVADSSQGVQSA
TIEKLAKYWATNYDWRKIEAKLNELPQFITEIDGVDIHFIHVKAKHDGALPIIVTHGWPGSIIEQMKIIGPLTDPTAHGG
SASDAFDVVIPSIPGYGFSGKPTEKGWDPIRIAHAWIELMKRLGYARYVAQGGDWGDAVTEQMALIAPPELLGIHVNMPA
TVPEDIATALQPGGKKPAGLSPDESHAYDQLADFYAHGLGYAIEMANRPQTLVGITDSPVGLAAWMIDHDIRSYELIARI
FDGRTEGLSRDDILDNITLYWLTNTAVSSARLYWENKLAFFQPKNVKIPVAVSVFPDEIYAAPRSWTEKAYANLIHFNRL
DKGGHFAAWEQTQLFCEEMRTSFRTVRS
>Mature_427_residues
SSTEHLVTRRTLLASAAAAGALIIMPQQVAFAKEGDERIRRFSFKASEEQLGDLRRRIEATRFPEPELVADSSQGVQSAT
IEKLAKYWATNYDWRKIEAKLNELPQFITEIDGVDIHFIHVKAKHDGALPIIVTHGWPGSIIEQMKIIGPLTDPTAHGGS
ASDAFDVVIPSIPGYGFSGKPTEKGWDPIRIAHAWIELMKRLGYARYVAQGGDWGDAVTEQMALIAPPELLGIHVNMPAT
VPEDIATALQPGGKKPAGLSPDESHAYDQLADFYAHGLGYAIEMANRPQTLVGITDSPVGLAAWMIDHDIRSYELIARIF
DGRTEGLSRDDILDNITLYWLTNTAVSSARLYWENKLAFFQPKNVKIPVAVSVFPDEIYAAPRSWTEKAYANLIHFNRLD
KGGHFAAWEQTQLFCEEMRTSFRTVRS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

Organism=Homo sapiens, GI4503583, Length=406, Percent_Identity=35.2216748768473, Blast_Score=249, Evalue=5e-66,
Organism=Homo sapiens, GI209862837, Length=406, Percent_Identity=35.2216748768473, Blast_Score=249, Evalue=5e-66,
Organism=Caenorhabditis elegans, GI17564944, Length=400, Percent_Identity=34, Blast_Score=212, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI193207462, Length=399, Percent_Identity=27.0676691729323, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI20130139, Length=420, Percent_Identity=29.5238095238095, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI19922580, Length=395, Percent_Identity=28.6075949367089, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24655327, Length=391, Percent_Identity=28.9002557544757, Blast_Score=160, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =3.3.2.10 [H]

Molecular weight: Translated: 47584; Mature: 47452

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTEHLVTRRTLLASAAAAGALIIMPQQVAFAKEGDERIRRFSFKASEEQLGDLRRRIE
CCCHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHH
ATRFPEPELVADSSQGVQSATIEKLAKYWATNYDWRKIEAKLNELPQFITEIDGVDIHFI
HHCCCCCCEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEE
HVKAKHDGALPIIVTHGWPGSIIEQMKIIGPLTDPTAHGGSASDAFDVVIPSIPGYGFSG
EEEECCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCC
KPTEKGWDPIRIAHAWIELMKRLGYARYVAQGGDWGDAVTEQMALIAPPELLGIHVNMPA
CCCCCCCCHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHCCCCHHEEEEECCCC
TVPEDIATALQPGGKKPAGLSPDESHAYDQLADFYAHGLGYAIEMANRPQTLVGITDSPV
CCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEECCCCC
GLAAWMIDHDIRSYELIARIFDGRTEGLSRDDILDNITLYWLTNTAVSSARLYWENKLAF
HHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHCEEEEEEECCHHHHHEEEEECCEEE
FQPKNVKIPVAVSVFPDEIYAAPRSWTEKAYANLIHFNRLDKGGHFAAWEQTQLFCEEMR
ECCCCEEEEEEEEECCHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHH
TSFRTVRS
HHHHHHCC
>Mature Secondary Structure 
SSTEHLVTRRTLLASAAAAGALIIMPQQVAFAKEGDERIRRFSFKASEEQLGDLRRRIE
CCHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHH
ATRFPEPELVADSSQGVQSATIEKLAKYWATNYDWRKIEAKLNELPQFITEIDGVDIHFI
HHCCCCCCEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEE
HVKAKHDGALPIIVTHGWPGSIIEQMKIIGPLTDPTAHGGSASDAFDVVIPSIPGYGFSG
EEEECCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCC
KPTEKGWDPIRIAHAWIELMKRLGYARYVAQGGDWGDAVTEQMALIAPPELLGIHVNMPA
CCCCCCCCHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHCCCCHHEEEEECCCC
TVPEDIATALQPGGKKPAGLSPDESHAYDQLADFYAHGLGYAIEMANRPQTLVGITDSPV
CCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEECCCCC
GLAAWMIDHDIRSYELIARIFDGRTEGLSRDDILDNITLYWLTNTAVSSARLYWENKLAF
HHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHCEEEEEEECCHHHHHEEEEECCEEE
FQPKNVKIPVAVSVFPDEIYAAPRSWTEKAYANLIHFNRLDKGGHFAAWEQTQLFCEEMR
ECCCCEEEEEEEEECCHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHH
TSFRTVRS
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226695 [H]