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The map label for this gene is ccmF

Identifier: 86361225

GI number: 86361225

Start: 560469

End: 561830

Strand: Reverse

Name: ccmF

Synonym: RHE_PF00496

Alternate gene names: 86361225

Gene position: 561830-560469 (Counterclockwise)

Preceding gene: 86361226

Following gene: 86361224

Centisome position: 87.44

GC content: 63.95

Gene sequence:

>1362_bases
ATGATCATCGAGATCGGCCATTACGCTCTGGTGCTGGCGCTGGCGACGGCGCTGATCGTCTCGATCGTGCCTGTCATCGG
CGCCCGCCGTCATGATCCGGCGCTGATGGATGTGGCGACATCAGGTTCGCTGGCGATGTTTGCCCTTGTCGCCTTTGCCT
TCGCCGTCTTGACCTATGCCCATGTCGTCTCCGACTTCTCCGTCGAGAACGTCTGGGAGAATTCGCATTCGCTGGTGCCG
CTGATCTACAAATATTCTGGCGTCTGGGGCAATCACGAGGGATCGATGATGCTCTGGCTGTTGATCCTGGCGCTGTTCAG
CGCGCTGGTCGCGATCTTCGGCGCCAATCTGCCGGAGATGCTGAAGGCCAATGTGCTTGCCGTGCAGGCCTGGATCTCGC
TCGCCTTCACCCTGTTCATCCTTTTGACCTCCAATCCCTTCCTGCGGCTCGATCCGGCCCCGGCCGAGGGCCGCGATCTC
AATCCGGTGCTGCAGGATGTCGGGCTCGCCATCCACCCGCCGCTGCTCTATCTCGGCTATGTCGGCTTTTCCGTCTGCTT
CTCCTTCGCCGTTGCCGCCCTCATTGAAGGCCGCATCGACGCCGCCTGGGCGCGCTGGGTCCGGCCCTGGACGCTCGCCG
CCTGGACCTGCCTGACATTAGGCATCGCCATGGGCTCCTACTGGGCCTATTACGAGCTCGGCTGGGGCGGCTGGTGGTTC
TGGGACCCGGTGGAAAACGCCTCGTTCATGCCGTGGCTCGCCGGCACCGCGCTGCTGCATTCGGCTCTCGTCATGGAAAA
GCGCGAGGCGCTGAAGATCTGGACGGTGCTGCTCGCCATCCTGACCTTCTCGCTGTCGCTGATGGGCACCTTCCTGGTGC
GCTCCGGGGTGCTGACCTCGGTGCATGCCTTTGCCAGCGATCCCACCCGCGGCGTCTTCATCCTGTCGATCCTGCTGATC
TTCATCGGCGGAGCGCTGTCGCTGTTTGCCCTGCGGGCGCCGAAGCTTGCGGCCGGCGGGCTGTTTGCGCCGATCTCGCG
CGAGGGGGCGCTCGTCCTCAACAATCTGATCCTGACGGTCGCCTGCGGCACGGTGCTGACCGGCACGCTCTATCCGCTGC
TGTTGGAAACGCTGACCGGCGACAAGATCTCCGTCGGGCCGCCCTTCTTCAACCTGACCTTCGGCCTGCTGATGGCGCCG
CTGCTCGTCATCGTGGCAGGGTCGCGCTTCTTTCGCGGCCGGCTGCGGAGCGGCGCGTCGGCGTCTCCGAGCAGCGGCTG
GGCGGGCTTGCGAGGCGGCTTTGTCATACCGCCAGTTGCTCAGCCAATTCTTAAAAGGCAATTGGCCCAGATTGAGTATT
GA

Upstream 100 bases:

>100_bases
CCAAGCATGACGAGACCTATATGCCGAAGGAGGTGGCCGACCGACTAAAGTCGCAGGGGCTGTGGCAGGAAGGCAAGGGG
CAGGAGGCGAAGGCGACGCC

Downstream 100 bases:

>100_bases
CGCTTCGTAAGTGCCCGGCGGGGAAAACAGTTCGGCTGTCTTGACCTGCTGAGGGAGGGTTATATCTAAATAAGTAGTCT
CCCCCATGGAATACGGAATG

Product: cytochrome c-type biogenesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MIIEIGHYALVLALATALIVSIVPVIGARRHDPALMDVATSGSLAMFALVAFAFAVLTYAHVVSDFSVENVWENSHSLVP
LIYKYSGVWGNHEGSMMLWLLILALFSALVAIFGANLPEMLKANVLAVQAWISLAFTLFILLTSNPFLRLDPAPAEGRDL
NPVLQDVGLAIHPPLLYLGYVGFSVCFSFAVAALIEGRIDAAWARWVRPWTLAAWTCLTLGIAMGSYWAYYELGWGGWWF
WDPVENASFMPWLAGTALLHSALVMEKREALKIWTVLLAILTFSLSLMGTFLVRSGVLTSVHAFASDPTRGVFILSILLI
FIGGALSLFALRAPKLAAGGLFAPISREGALVLNNLILTVACGTVLTGTLYPLLLETLTGDKISVGPPFFNLTFGLLMAP
LLVIVAGSRFFRGRLRSGASASPSSGWAGLRGGFVIPPVAQPILKRQLAQIEY

Sequences:

>Translated_453_residues
MIIEIGHYALVLALATALIVSIVPVIGARRHDPALMDVATSGSLAMFALVAFAFAVLTYAHVVSDFSVENVWENSHSLVP
LIYKYSGVWGNHEGSMMLWLLILALFSALVAIFGANLPEMLKANVLAVQAWISLAFTLFILLTSNPFLRLDPAPAEGRDL
NPVLQDVGLAIHPPLLYLGYVGFSVCFSFAVAALIEGRIDAAWARWVRPWTLAAWTCLTLGIAMGSYWAYYELGWGGWWF
WDPVENASFMPWLAGTALLHSALVMEKREALKIWTVLLAILTFSLSLMGTFLVRSGVLTSVHAFASDPTRGVFILSILLI
FIGGALSLFALRAPKLAAGGLFAPISREGALVLNNLILTVACGTVLTGTLYPLLLETLTGDKISVGPPFFNLTFGLLMAP
LLVIVAGSRFFRGRLRSGASASPSSGWAGLRGGFVIPPVAQPILKRQLAQIEY
>Mature_453_residues
MIIEIGHYALVLALATALIVSIVPVIGARRHDPALMDVATSGSLAMFALVAFAFAVLTYAHVVSDFSVENVWENSHSLVP
LIYKYSGVWGNHEGSMMLWLLILALFSALVAIFGANLPEMLKANVLAVQAWISLAFTLFILLTSNPFLRLDPAPAEGRDL
NPVLQDVGLAIHPPLLYLGYVGFSVCFSFAVAALIEGRIDAAWARWVRPWTLAAWTCLTLGIAMGSYWAYYELGWGGWWF
WDPVENASFMPWLAGTALLHSALVMEKREALKIWTVLLAILTFSLSLMGTFLVRSGVLTSVHAFASDPTRGVFILSILLI
FIGGALSLFALRAPKLAAGGLFAPISREGALVLNNLILTVACGTVLTGTLYPLLLETLTGDKISVGPPFFNLTFGLLMAP
LLVIVAGSRFFRGRLRSGASASPSSGWAGLRGGFVIPPVAQPILKRQLAQIEY

Specific function: Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase [H]

COG id: COG1138

COG function: function code O; Cytochrome c biogenesis factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ccmF/cycK/ccl1/nrfE/ccsA family [H]

Homologues:

Organism=Escherichia coli, GI1788524, Length=418, Percent_Identity=54.3062200956938, Blast_Score=404, Evalue=1e-114,
Organism=Escherichia coli, GI1790511, Length=391, Percent_Identity=47.0588235294118, Blast_Score=272, Evalue=3e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003567
- InterPro:   IPR003568 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 48963; Mature: 48963

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIEIGHYALVLALATALIVSIVPVIGARRHDPALMDVATSGSLAMFALVAFAFAVLTYA
CEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHH
HVVSDFSVENVWENSHSLVPLIYKYSGVWGNHEGSMMLWLLILALFSALVAIFGANLPEM
HHHHCCHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHH
LKANVLAVQAWISLAFTLFILLTSNPFLRLDPAPAEGRDLNPVLQDVGLAIHPPLLYLGY
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHCCCCCCCHHHHHHH
VGFSVCFSFAVAALIEGRIDAAWARWVRPWTLAAWTCLTLGIAMGSYWAYYELGWGGWWF
HHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEE
WDPVENASFMPWLAGTALLHSALVMEKREALKIWTVLLAILTFSLSLMGTFLVRSGVLTS
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VHAFASDPTRGVFILSILLIFIGGALSLFALRAPKLAAGGLFAPISREGALVLNNLILTV
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
ACGTVLTGTLYPLLLETLTGDKISVGPPFFNLTFGLLMAPLLVIVAGSRFFRGRLRSGAS
HHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCC
ASPSSGWAGLRGGFVIPPVAQPILKRQLAQIEY
CCCCCCCCCCCCCEECCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIIEIGHYALVLALATALIVSIVPVIGARRHDPALMDVATSGSLAMFALVAFAFAVLTYA
CEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHH
HVVSDFSVENVWENSHSLVPLIYKYSGVWGNHEGSMMLWLLILALFSALVAIFGANLPEM
HHHHCCHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHH
LKANVLAVQAWISLAFTLFILLTSNPFLRLDPAPAEGRDLNPVLQDVGLAIHPPLLYLGY
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHCCCCCCCHHHHHHH
VGFSVCFSFAVAALIEGRIDAAWARWVRPWTLAAWTCLTLGIAMGSYWAYYELGWGGWWF
HHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEE
WDPVENASFMPWLAGTALLHSALVMEKREALKIWTVLLAILTFSLSLMGTFLVRSGVLTS
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VHAFASDPTRGVFILSILLIFIGGALSLFALRAPKLAAGGLFAPISREGALVLNNLILTV
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
ACGTVLTGTLYPLLLETLTGDKISVGPPFFNLTFGLLMAPLLVIVAGSRFFRGRLRSGAS
HHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCC
ASPSSGWAGLRGGFVIPPVAQPILKRQLAQIEY
CCCCCCCCCCCCCEECCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7715602; 11481430 [H]