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The map label for this gene is degS [H]

Identifier: 86361210

GI number: 86361210

Start: 540684

End: 541916

Strand: Reverse

Name: degS [H]

Synonym: RHE_PF00480

Alternate gene names: 86361210

Gene position: 541916-540684 (Counterclockwise)

Preceding gene: 86361216

Following gene: 86361209

Centisome position: 84.34

GC content: 65.29

Gene sequence:

>1233_bases
ATGCTGCATCTCGCACCGGCAGCCCTGTTCGATCACTATCTCGGCATATCCCGGCTGCTCGCGGGCCAGCTCGACTTTCG
CTCGGCCATCCGGTCGGTGGCTGCCGAGGTCGCTCACATCATTCCGCACGACCATCTCGATGTCTGCGTGCTGCTCGAAG
GCGGCAACTATCACACGGCCTATGAGACGGGCATCGAGACCGCCTGGGGCGAGATTGCCGGTGCGCCCGTTATCAACAGC
CCCATCCGCTCGCTCCTGCGGGGTGAGGTCGACTTTCTGCTCTCGGACGACGCCATGAAAGATCCGCGCTTCCACTTCGA
GGGGGCGTTCAAGCGGCCGATCGTAGAACAATCGCTGAGGAGCCGGCTGCATGTGCCGATGAAGGTGCAAGGCACGATCA
TCGCAGCGCTTTCCTGTTCGTCTCACAGGGCGGGCGTCTATACGATGGAAGACGTCGAGCGCGCCCGCATCATCGCCGAT
CTGCTGACGCCCTATTTCTTCGCGCTGCAGGCGGCCGAGCAGGCGCAGCGCTCAGCGATCGTCGAGGCCGAAGCCCGCGC
CCGCGAAGAGGGGCTGCGGCAAGGTGCGCTGAAGCTGACCGAAGCCCTGGAGCAGGAGCGTCAGCGGATCGGCATGGACC
TTCATGACCAGACGCTTGCCGACCTGACGCGGCTCGCCCGGCGGATCGACCGGTTGTCGCGCAACGGCGAGGTGACGCCC
GAGGCGCTCGAACCTGTTTCGCGGTCCCTGCAGCATTGCATGCAGGATCTGCGGCAGATCATCGAGCAAGCAAAACCCTC
CGTGCTCCAGCTCTTCGGCCTCGCACAGGCGATCGAGCATCATCTCGACCGATCGACCCGCGACACCGGATCGGGCATCG
AATGGGGCCTTGTCGACGAGACGAACGGCGCGCTGGAAAGGCTGGAACCGACCGTCAGCGTCGCCTTGTTCCGAATCGCG
CAGGAGGCGATCAACAATGCCGTGCGCCATGCCGCCCCGCTGGCGATCATGGTGCGGCTCGAAGCCGACGACGAACAGCT
GTCGATCGAAATCTCCGACGACGGGACCGGCCTTGCCAAGACACGGGGGCGGATCGGCGGCGGCATCGACAATATGAAGA
CCCGCGCACGGCTGATCTCGGCGCGCTTTACGATCGGCCCCGGCCATAATAGTCGCGGGACCGCGGTGCGCGTCATGCTG
CCGCTTGGCGGCCCGGCGGGCGAGCCAGACTGA

Upstream 100 bases:

>100_bases
AAGCTGCGGGTTTACGCAAGACGGCGGCCCGTCCGCGGGCGCTTACTGGGAAGCGATCACGGCGGGTTGAGGAGCCTGTC
GTGACGGGGAGGAACTGACA

Downstream 100 bases:

>100_bases
GGAGAAAGGCACGATGAAAGTTTTGATCGTCGAGGACGACCCGCTGCACCGGTCCTATCTGCACGAGGCTGTCAACGCTG
CCCTGCCGGAATGCGACACG

Product: two-component sensor histidine kinase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MLHLAPAALFDHYLGISRLLAGQLDFRSAIRSVAAEVAHIIPHDHLDVCVLLEGGNYHTAYETGIETAWGEIAGAPVINS
PIRSLLRGEVDFLLSDDAMKDPRFHFEGAFKRPIVEQSLRSRLHVPMKVQGTIIAALSCSSHRAGVYTMEDVERARIIAD
LLTPYFFALQAAEQAQRSAIVEAEARAREEGLRQGALKLTEALEQERQRIGMDLHDQTLADLTRLARRIDRLSRNGEVTP
EALEPVSRSLQHCMQDLRQIIEQAKPSVLQLFGLAQAIEHHLDRSTRDTGSGIEWGLVDETNGALERLEPTVSVALFRIA
QEAINNAVRHAAPLAIMVRLEADDEQLSIEISDDGTGLAKTRGRIGGGIDNMKTRARLISARFTIGPGHNSRGTAVRVML
PLGGPAGEPD

Sequences:

>Translated_410_residues
MLHLAPAALFDHYLGISRLLAGQLDFRSAIRSVAAEVAHIIPHDHLDVCVLLEGGNYHTAYETGIETAWGEIAGAPVINS
PIRSLLRGEVDFLLSDDAMKDPRFHFEGAFKRPIVEQSLRSRLHVPMKVQGTIIAALSCSSHRAGVYTMEDVERARIIAD
LLTPYFFALQAAEQAQRSAIVEAEARAREEGLRQGALKLTEALEQERQRIGMDLHDQTLADLTRLARRIDRLSRNGEVTP
EALEPVSRSLQHCMQDLRQIIEQAKPSVLQLFGLAQAIEHHLDRSTRDTGSGIEWGLVDETNGALERLEPTVSVALFRIA
QEAINNAVRHAAPLAIMVRLEADDEQLSIEISDDGTGLAKTRGRIGGGIDNMKTRARLISARFTIGPGHNSRGTAVRVML
PLGGPAGEPD
>Mature_410_residues
MLHLAPAALFDHYLGISRLLAGQLDFRSAIRSVAAEVAHIIPHDHLDVCVLLEGGNYHTAYETGIETAWGEIAGAPVINS
PIRSLLRGEVDFLLSDDAMKDPRFHFEGAFKRPIVEQSLRSRLHVPMKVQGTIIAALSCSSHRAGVYTMEDVERARIIAD
LLTPYFFALQAAEQAQRSAIVEAEARAREEGLRQGALKLTEALEQERQRIGMDLHDQTLADLTRLARRIDRLSRNGEVTP
EALEPVSRSLQHCMQDLRQIIEQAKPSVLQLFGLAQAIEHHLDRSTRDTGSGIEWGLVDETNGALERLEPTVSVALFRIA
QEAINNAVRHAAPLAIMVRLEADDEQLSIEISDDGTGLAKTRGRIGGGIDNMKTRARLISARFTIGPGHNSRGTAVRVML
PLGGPAGEPD

Specific function: Member of the two-component regulatory system degS/degU. Involved in a sensory transduction pathway that affect the production of enzymes that degrade polymeric carbon and nitrogen sources. DegS probably acts as a kinase that phosphorylates degU [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR008595
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR016381 [H]

Pfam domain/function: PF05384 DegS; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 44983; Mature: 44983

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHLAPAALFDHYLGISRLLAGQLDFRSAIRSVAAEVAHIIPHDHLDVCVLLEGGNYHTA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCH
YETGIETAWGEIAGAPVINSPIRSLLRGEVDFLLSDDAMKDPRFHFEGAFKRPIVEQSLR
HHHCHHHHHHHHCCCCCCHHHHHHHHCCCHHEEECCCCCCCCCCCCCCCCCCHHHHHHHH
SRLHVPMKVQGTIIAALSCSSHRAGVYTMEDVERARIIADLLTPYFFALQAAEQAQRSAI
HHCCCCEEECCEEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEAEARAREEGLRQGALKLTEALEQERQRIGMDLHDQTLADLTRLARRIDRLSRNGEVTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCH
EALEPVSRSLQHCMQDLRQIIEQAKPSVLQLFGLAQAIEHHLDRSTRDTGSGIEWGLVDE
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECEEEC
TNGALERLEPTVSVALFRIAQEAINNAVRHAAPLAIMVRLEADDEQLSIEISDDGTGLAK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCEEEEEECCCCCCHHH
TRGRIGGGIDNMKTRARLISARFTIGPGHNSRGTAVRVMLPLGGPAGEPD
HCCCCCCCHHHHHHHHHHHHHEEEECCCCCCCCCEEEEEEECCCCCCCCC
>Mature Secondary Structure
MLHLAPAALFDHYLGISRLLAGQLDFRSAIRSVAAEVAHIIPHDHLDVCVLLEGGNYHTA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCH
YETGIETAWGEIAGAPVINSPIRSLLRGEVDFLLSDDAMKDPRFHFEGAFKRPIVEQSLR
HHHCHHHHHHHHCCCCCCHHHHHHHHCCCHHEEECCCCCCCCCCCCCCCCCCHHHHHHHH
SRLHVPMKVQGTIIAALSCSSHRAGVYTMEDVERARIIADLLTPYFFALQAAEQAQRSAI
HHCCCCEEECCEEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEAEARAREEGLRQGALKLTEALEQERQRIGMDLHDQTLADLTRLARRIDRLSRNGEVTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCH
EALEPVSRSLQHCMQDLRQIIEQAKPSVLQLFGLAQAIEHHLDRSTRDTGSGIEWGLVDE
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECEEEC
TNGALERLEPTVSVALFRIAQEAINNAVRHAAPLAIMVRLEADDEQLSIEISDDGTGLAK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCEEEEEECCCCCCHHH
TRGRIGGGIDNMKTRARLISARFTIGPGHNSRGTAVRVMLPLGGPAGEPD
HCCCCCCCHHHHHHHHHHHHHEEEECCCCCCCCCEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3141378; 3141377; 9384377; 3136143 [H]