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The map label for this gene is trkA

Identifier: 85860672

GI number: 85860672

Start: 2847536

End: 2848882

Strand: Direct

Name: trkA

Synonym: SYN_02618

Alternate gene names: 85860672

Gene position: 2847536-2848882 (Clockwise)

Preceding gene: 85860667

Following gene: 85860673

Centisome position: 89.56

GC content: 56.42

Gene sequence:

>1347_bases
ATGCGGATCATTATTGTCGGAGCTGGAGAGGTGGGTTCCCATCTGAGTGAGAGTCTCTCCCTCGAAGGCCATGAGGTTGT
GCTGATCGATCGGAACACGGAACGGATCCGGTATCTGGAAAAGAAGCTGGACGTGCTGACCATTGTCGGAAACGGCGCTT
CGGCGCAGGTTCTGGAGCACGGAGGCATCAAGGATACCGACCTCTTCATCGCCGTAACCGATATCGATGAAGTCAATCTG
GTGGCTTCCATCCTCGCCCGGGAATACCATGTGAAACATCGCGTGGCCCGTGTCCGCAACGAGGAATTCCTTTCCCCGGG
GTCTCCGCTCAATGAAACTCGATTGGGTCTGGATCTGCTCATCAATCCGGACCGGGTCATGGCCGAGGAAATCCTGAGGC
TTGTCGATCTCTCCGAGGCCTTCGATTTCTTTGAATTTGCCGACGGCCAGGTGGTTCTGTTGGGATACCGCATCAAGGAA
AATAATCCGATCTGTGGCCTGACCATGCAGGAACTCGGGGAAATCCGAGGAATCTACGATTTCGTGATCGTTTCCATCCT
TCGGGGCAATCAGGCATTGATCCCGCGCGGCCCCGATGTCATCGAGGCCGGCGACAGCATCTACCTGACAGCCCGTCGTT
CGGAAATCCCCAACGTGGAGTACCTCCTGAATCTTTCCAGCAAGGCCCCCAAACGGATTTTCATCATTGGAGGCGGACGG
GTGGGTTCTCTGGTGGCCCGGCAGATGGAAAGCCGTCGGGTCGATGTCCGCCTCGTCGAGAAGGATTCTGACCGCTGCCA
GAAGTTATCCGAGGTTTTAGAAAAAACCATTCTTCTGAATCTGGACGGCATGGATTCAAGAGAATTGCTGGAAGAGGGCA
TTGACCGCGCCGACCTGGTCATTGCCGTCACCGGCGATGACGATGTAAATATCCTGTCAAGCCTGCTGGCAAAGCACCAT
GGCACGGCCAAGTGCATAACCCGCATCGACCGCCCGGACTTCATCCCTCTGCTGGAAAAACTGGGGGTCGACATGGCCCT
GAGCCCCAGACTGCTCGCCGCCGGCACCATTCTGAAGTTCGTGAGGCGCGGCTCAATTCGCGCGGTGGCCAACATCCTGA
GAGTCGATGCGGAAGTTCTGGAAATGGTCGTGCCCGACAAGCCGCATTTCCGGCAACAGCCGATCAGGAAATTAAGGTTC
CCCGACAGAGCGATCATGGGGGCGGTCGTCCGCAAAGACCGGGTGCTGATTCCCACCGGCGACACGATTCTGGAACCGAA
GGATGATGTCATCATCTTTGCTCTCCACGATGCGATTCCGGAAGTGGAACTCTTCTTCGAGCCATGA

Upstream 100 bases:

>100_bases
CGAAAATCGACGTCTTTATCGACTCAGTTTTTTCTGAGAAGATGTCATCATGAACGATATTCTCCGGACAGGCGAAGCCT
TGTCGAAGGGCATCTGAACC

Downstream 100 bases:

>100_bases
AAACCGGGACGGTCCTGCACATCCTCGGCGGATTGCTGCTGTTTCTGTCGGCCGCCCTCCTTATTCCCACCCCGTTCAGT
TATTATTATCAGGACGGCCA

Product: potassium transporter peripheral membrane component

Products: NA

Alternate protein names: K(+)-uptake protein trkA homolog 1 [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MRIIIVGAGEVGSHLSESLSLEGHEVVLIDRNTERIRYLEKKLDVLTIVGNGASAQVLEHGGIKDTDLFIAVTDIDEVNL
VASILAREYHVKHRVARVRNEEFLSPGSPLNETRLGLDLLINPDRVMAEEILRLVDLSEAFDFFEFADGQVVLLGYRIKE
NNPICGLTMQELGEIRGIYDFVIVSILRGNQALIPRGPDVIEAGDSIYLTARRSEIPNVEYLLNLSSKAPKRIFIIGGGR
VGSLVARQMESRRVDVRLVEKDSDRCQKLSEVLEKTILLNLDGMDSRELLEEGIDRADLVIAVTGDDDVNILSSLLAKHH
GTAKCITRIDRPDFIPLLEKLGVDMALSPRLLAAGTILKFVRRGSIRAVANILRVDAEVLEMVVPDKPHFRQQPIRKLRF
PDRAIMGAVVRKDRVLIPTGDTILEPKDDVIIFALHDAIPEVELFFEP

Sequences:

>Translated_448_residues
MRIIIVGAGEVGSHLSESLSLEGHEVVLIDRNTERIRYLEKKLDVLTIVGNGASAQVLEHGGIKDTDLFIAVTDIDEVNL
VASILAREYHVKHRVARVRNEEFLSPGSPLNETRLGLDLLINPDRVMAEEILRLVDLSEAFDFFEFADGQVVLLGYRIKE
NNPICGLTMQELGEIRGIYDFVIVSILRGNQALIPRGPDVIEAGDSIYLTARRSEIPNVEYLLNLSSKAPKRIFIIGGGR
VGSLVARQMESRRVDVRLVEKDSDRCQKLSEVLEKTILLNLDGMDSRELLEEGIDRADLVIAVTGDDDVNILSSLLAKHH
GTAKCITRIDRPDFIPLLEKLGVDMALSPRLLAAGTILKFVRRGSIRAVANILRVDAEVLEMVVPDKPHFRQQPIRKLRF
PDRAIMGAVVRKDRVLIPTGDTILEPKDDVIIFALHDAIPEVELFFEP
>Mature_448_residues
MRIIIVGAGEVGSHLSESLSLEGHEVVLIDRNTERIRYLEKKLDVLTIVGNGASAQVLEHGGIKDTDLFIAVTDIDEVNL
VASILAREYHVKHRVARVRNEEFLSPGSPLNETRLGLDLLINPDRVMAEEILRLVDLSEAFDFFEFADGQVVLLGYRIKE
NNPICGLTMQELGEIRGIYDFVIVSILRGNQALIPRGPDVIEAGDSIYLTARRSEIPNVEYLLNLSSKAPKRIFIIGGGR
VGSLVARQMESRRVDVRLVEKDSDRCQKLSEVLEKTILLNLDGMDSRELLEEGIDRADLVIAVTGDDDVNILSSLLAKHH
GTAKCITRIDRPDFIPLLEKLGVDMALSPRLLAAGTILKFVRRGSIRAVANILRVDAEVLEMVVPDKPHFRQQPIRKLRF
PDRAIMGAVVRKDRVLIPTGDTILEPKDDVIIFALHDAIPEVELFFEP

Specific function: Part of a potassium transport system [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Peripherally Bound To The Inner Side Of The Inner Membrane Via The Trkg And Trkh Proteins [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 RCK N-terminal domains [H]

Homologues:

Organism=Escherichia coli, GI1789685, Length=455, Percent_Identity=34.0659340659341, Blast_Score=247, Evalue=1e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 49956; Mature: 49956

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIIIVGAGEVGSHLSESLSLEGHEVVLIDRNTERIRYLEKKLDVLTIVGNGASAQVLEH
CEEEEEECCHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHCCEEEEEECCCCHHHHHC
GGIKDTDLFIAVTDIDEVNLVASILAREYHVKHRVARVRNEEFLSPGSPLNETRLGLDLL
CCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHCCEEEE
INPDRVMAEEILRLVDLSEAFDFFEFADGQVVLLGYRIKENNPICGLTMQELGEIRGIYD
ECCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCEEECCHHHHHHHHHHHH
FVIVSILRGNQALIPRGPDVIEAGDSIYLTARRSEIPNVEYLLNLSSKAPKRIFIIGGGR
HHHHHHHCCCEEECCCCCCCEECCCEEEEEEECCCCCCEEEEEECCCCCCCEEEEEECCC
VGSLVARQMESRRVDVRLVEKDSDRCQKLSEVLEKTILLNLDGMDSRELLEEGIDRADLV
HHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHEEEECCCCCHHHHHHHCCCCEEEE
IAVTGDDDVNILSSLLAKHHGTAKCITRIDRPDFIPLLEKLGVDMALSPRLLAAGTILKF
EEEECCCCHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHCCCCEECCCHHHHHHHHHHH
VRRGSIRAVANILRVDAEVLEMVVPDKPHFRQQPIRKLRFPDRAIMGAVVRKDRVLIPTG
HHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCEEEEECC
DTILEPKDDVIIFALHDAIPEVELFFEP
CCCCCCCCCEEEEEECCCCCCEEEEECC
>Mature Secondary Structure
MRIIIVGAGEVGSHLSESLSLEGHEVVLIDRNTERIRYLEKKLDVLTIVGNGASAQVLEH
CEEEEEECCHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHCCEEEEEECCCCHHHHHC
GGIKDTDLFIAVTDIDEVNLVASILAREYHVKHRVARVRNEEFLSPGSPLNETRLGLDLL
CCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHCCEEEE
INPDRVMAEEILRLVDLSEAFDFFEFADGQVVLLGYRIKENNPICGLTMQELGEIRGIYD
ECCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCEEECCHHHHHHHHHHHH
FVIVSILRGNQALIPRGPDVIEAGDSIYLTARRSEIPNVEYLLNLSSKAPKRIFIIGGGR
HHHHHHHCCCEEECCCCCCCEECCCEEEEEEECCCCCCEEEEEECCCCCCCEEEEEECCC
VGSLVARQMESRRVDVRLVEKDSDRCQKLSEVLEKTILLNLDGMDSRELLEEGIDRADLV
HHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHEEEECCCCCHHHHHHHCCCCEEEE
IAVTGDDDVNILSSLLAKHHGTAKCITRIDRPDFIPLLEKLGVDMALSPRLLAAGTILKF
EEEECCCCHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHCCCCEECCCHHHHHHHHHHH
VRRGSIRAVANILRVDAEVLEMVVPDKPHFRQQPIRKLRFPDRAIMGAVVRKDRVLIPTG
HHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCEEEEECC
DTILEPKDDVIIFALHDAIPEVELFFEP
CCCCCCCCCEEEEEECCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8268235; 12125824 [H]