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The map label for this gene is trkH [H]

Identifier: 85860673

GI number: 85860673

Start: 2848879

End: 2850366

Strand: Direct

Name: trkH [H]

Synonym: SYN_02617

Alternate gene names: 85860673

Gene position: 2848879-2850366 (Clockwise)

Preceding gene: 85860672

Following gene: 85860676

Centisome position: 89.61

GC content: 57.26

Gene sequence:

>1488_bases
ATGAAAACCGGGACGGTCCTGCACATCCTCGGCGGATTGCTGCTGTTTCTGTCGGCCGCCCTCCTTATTCCCACCCCGTT
CAGTTATTATTATCAGGACGGCCAGATCGCCTCTTTTCTCTGGTCGGCCCTGATCACCGCTCTTGCCGGTTTCCTGCTGC
GCAGCCTTTTCGTCCCGGAAGGCGACCTGGGTTTTCGGGACGGATTTGCCATTGTCACCCTCGGATGGCTGGGAGCTGCC
TTTTTCGGCGCCCTGCCCTTTCACTTCTCCGGGGAATTTTCGGGCTTTCTGGATTGTTTTTTTGAATCCATGTCCGGCTT
CACCACCACCGGCTCTTCGGTCCTGGAAAAAGTGGAGGTGCTGGCTCCCAGTACTCACTTCTGGCGAACCTTCATTCAGT
GGCTGGGAGGCATGGGAATCATCGTCCTTTCTCTGGCCATCCTGCCCGTCCTGGGCATCGGGGGAATGCAGCTTTTTCAG
GCGGAGGTTCCAGGACCTACCAAGGACCGCCTCTCACCCCGGATCCGCGATACGGCGCGGATACTCTGGGCGGTGTATCT
TCTCCTGACCCTTTTTGAAACAGGGCTGCTCATGGCCGGGGGGCTCTCGGCATTCGATGCCCTTTGCCACTCCTTTGCCA
CTCTGGCCACCGGGGGATTTTCCCTGTACACTCCCAGTATCGGCAAGTTCAACAGTCTGTGGGTGGAATGCGTGGTGGCG
TTCTTCATGTTTGCCGCGGGCGTCAATTTCACCCTCCATTATTACGTTATGCAGGGACGGGGTTCCGCCTATTGGAAAAG
CGATGAGTTCCGTTTTTACCTTTTCCTGACCCTGCTGGCCACGGCCCTGCTCACCGTTTTCAACTTTGCGGGCAAAGCCT
ACGGGAGCCTTGGGGAAAGCCTTCGCTACAGCCTTTTCCAGGTCTGTTCAATCATGACCACCACCGGGTTTGCCACAGCT
GATTTTGACCAATGGCCTTATGTGTCCAGGTTTCTGCTTGTCTGCCTGATGTTTTTCGGAGGGTGTGCCGGCTCGACGGC
AGGTGGGATTAAGCATGTGCGGGTTCTGCTCCTTTGGAGGCACTTCAGATTACAGGTGTTCCAGTTGCTGCACCCCAAGG
CGGTCAAGGCCGTCAAACTGGACGGGACAAAAGTCGCCCCGGCGGTCATGCAGGCCGTCCTGGGTTTCTTTTTCCTCTAT
ATTGGCGTGTTTGCCTCGGCCAGTATGGCGGTCTGCGCCCAGGGCGTGGATTTGATCACCGCCGTCAGCGCCGTGGCCAC
CACCCTGAACAACATCGGCCCGGGCCTGGGCGGAGTTGGTCCCATGGCGAATTTCGGAAACCTGCCCGACTTCTCCAAAC
TGGTCCTGTCCGTCTGCATGCTGGTCGGCCGGCTTGAGTTGTTCACCGTGATGGTCCTCCTTTTCCCCTCCTTCTGGAAG
GAAACCCGGAAACCGCTCTGGTTCTGGCAAAGGAAGAAATTAAAGTAA

Upstream 100 bases:

>100_bases
TGCTGATTCCCACCGGCGACACGATTCTGGAACCGAAGGATGATGTCATCATCTTTGCTCTCCACGATGCGATTCCGGAA
GTGGAACTCTTCTTCGAGCC

Downstream 100 bases:

>100_bases
TTGAAATGATTTCAGCCGAAGAGAATTCTCTTTTTGAAAAGGCTGGCTTCTTCAGTTCTTTGCCGCTTTGTTTCTTCCTG
TAGTCGTTCATTTTGAATTT

Product: trk system potassium uptake protein

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 495

Protein sequence:

>495_residues
MKTGTVLHILGGLLLFLSAALLIPTPFSYYYQDGQIASFLWSALITALAGFLLRSLFVPEGDLGFRDGFAIVTLGWLGAA
FFGALPFHFSGEFSGFLDCFFESMSGFTTTGSSVLEKVEVLAPSTHFWRTFIQWLGGMGIIVLSLAILPVLGIGGMQLFQ
AEVPGPTKDRLSPRIRDTARILWAVYLLLTLFETGLLMAGGLSAFDALCHSFATLATGGFSLYTPSIGKFNSLWVECVVA
FFMFAAGVNFTLHYYVMQGRGSAYWKSDEFRFYLFLTLLATALLTVFNFAGKAYGSLGESLRYSLFQVCSIMTTTGFATA
DFDQWPYVSRFLLVCLMFFGGCAGSTAGGIKHVRVLLLWRHFRLQVFQLLHPKAVKAVKLDGTKVAPAVMQAVLGFFFLY
IGVFASASMAVCAQGVDLITAVSAVATTLNNIGPGLGGVGPMANFGNLPDFSKLVLSVCMLVGRLELFTVMVLLFPSFWK
ETRKPLWFWQRKKLK

Sequences:

>Translated_495_residues
MKTGTVLHILGGLLLFLSAALLIPTPFSYYYQDGQIASFLWSALITALAGFLLRSLFVPEGDLGFRDGFAIVTLGWLGAA
FFGALPFHFSGEFSGFLDCFFESMSGFTTTGSSVLEKVEVLAPSTHFWRTFIQWLGGMGIIVLSLAILPVLGIGGMQLFQ
AEVPGPTKDRLSPRIRDTARILWAVYLLLTLFETGLLMAGGLSAFDALCHSFATLATGGFSLYTPSIGKFNSLWVECVVA
FFMFAAGVNFTLHYYVMQGRGSAYWKSDEFRFYLFLTLLATALLTVFNFAGKAYGSLGESLRYSLFQVCSIMTTTGFATA
DFDQWPYVSRFLLVCLMFFGGCAGSTAGGIKHVRVLLLWRHFRLQVFQLLHPKAVKAVKLDGTKVAPAVMQAVLGFFFLY
IGVFASASMAVCAQGVDLITAVSAVATTLNNIGPGLGGVGPMANFGNLPDFSKLVLSVCMLVGRLELFTVMVLLFPSFWK
ETRKPLWFWQRKKLK
>Mature_495_residues
MKTGTVLHILGGLLLFLSAALLIPTPFSYYYQDGQIASFLWSALITALAGFLLRSLFVPEGDLGFRDGFAIVTLGWLGAA
FFGALPFHFSGEFSGFLDCFFESMSGFTTTGSSVLEKVEVLAPSTHFWRTFIQWLGGMGIIVLSLAILPVLGIGGMQLFQ
AEVPGPTKDRLSPRIRDTARILWAVYLLLTLFETGLLMAGGLSAFDALCHSFATLATGGFSLYTPSIGKFNSLWVECVVA
FFMFAAGVNFTLHYYVMQGRGSAYWKSDEFRFYLFLTLLATALLTVFNFAGKAYGSLGESLRYSLFQVCSIMTTTGFATA
DFDQWPYVSRFLLVCLMFFGGCAGSTAGGIKHVRVLLLWRHFRLQVFQLLHPKAVKAVKLDGTKVAPAVMQAVLGFFFLY
IGVFASASMAVCAQGVDLITAVSAVATTLNNIGPGLGGVGPMANFGNLPDFSKLVLSVCMLVGRLELFTVMVLLFPSFWK
ETRKPLWFWQRKKLK

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=485, Percent_Identity=41.0309278350515, Blast_Score=313, Evalue=1e-86,
Organism=Escherichia coli, GI1787626, Length=419, Percent_Identity=37.708830548926, Blast_Score=280, Evalue=2e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 54240; Mature: 54240

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTGTVLHILGGLLLFLSAALLIPTPFSYYYQDGQIASFLWSALITALAGFLLRSLFVPE
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
GDLGFRDGFAIVTLGWLGAAFFGALPFHFSGEFSGFLDCFFESMSGFTTTGSSVLEKVEV
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHH
LAPSTHFWRTFIQWLGGMGIIVLSLAILPVLGIGGMQLFQAEVPGPTKDRLSPRIRDTAR
HCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHCCCHHHHHHH
ILWAVYLLLTLFETGLLMAGGLSAFDALCHSFATLATGGFSLYTPSIGKFNSLWVECVVA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHH
FFMFAAGVNFTLHYYVMQGRGSAYWKSDEFRFYLFLTLLATALLTVFNFAGKAYGSLGES
HHHHHCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRYSLFQVCSIMTTTGFATADFDQWPYVSRFLLVCLMFFGGCAGSTAGGIKHVRVLLLWR
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
HFRLQVFQLLHPKAVKAVKLDGTKVAPAVMQAVLGFFFLYIGVFASASMAVCAQGVDLIT
HHHHHHHHHHCHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AVSAVATTLNNIGPGLGGVGPMANFGNLPDFSKLVLSVCMLVGRLELFTVMVLLFPSFWK
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETRKPLWFWQRKKLK
HHCCCHHHHHHHCCC
>Mature Secondary Structure
MKTGTVLHILGGLLLFLSAALLIPTPFSYYYQDGQIASFLWSALITALAGFLLRSLFVPE
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
GDLGFRDGFAIVTLGWLGAAFFGALPFHFSGEFSGFLDCFFESMSGFTTTGSSVLEKVEV
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHH
LAPSTHFWRTFIQWLGGMGIIVLSLAILPVLGIGGMQLFQAEVPGPTKDRLSPRIRDTAR
HCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHCCCHHHHHHH
ILWAVYLLLTLFETGLLMAGGLSAFDALCHSFATLATGGFSLYTPSIGKFNSLWVECVVA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHH
FFMFAAGVNFTLHYYVMQGRGSAYWKSDEFRFYLFLTLLATALLTVFNFAGKAYGSLGES
HHHHHCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRYSLFQVCSIMTTTGFATADFDQWPYVSRFLLVCLMFFGGCAGSTAGGIKHVRVLLLWR
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
HFRLQVFQLLHPKAVKAVKLDGTKVAPAVMQAVLGFFFLYIGVFASASMAVCAQGVDLIT
HHHHHHHHHHCHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AVSAVATTLNNIGPGLGGVGPMANFGNLPDFSKLVLSVCMLVGRLELFTVMVLLFPSFWK
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETRKPLWFWQRKKLK
HHCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]