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The map label for this gene is yfbQ [C]

Identifier: 85860426

GI number: 85860426

Start: 2593528

End: 2594874

Strand: Direct

Name: yfbQ [C]

Synonym: SYN_02699

Alternate gene names: 85860426

Gene position: 2593528-2594874 (Clockwise)

Preceding gene: 85860424

Following gene: 85860427

Centisome position: 81.58

GC content: 56.2

Gene sequence:

>1347_bases
TTGAGAACCACTGAATCGCAGCGAGGTGTTTGCCTAATGAGACTCGATATAGCCAAAGGCGGAACCGGTCTGGTTTATGA
GATCCGCAACATCGTCAACGTCGCCAACCGGCTTAAGGAATATGGAATTGATGTGATCTGGGAAAATATCGGCGATCCCA
TCCAGAAAGGGGAGCAGCTTCCCGGCTGGATGAAGGAGACCCTGACCGAAATCATGCAGGACGACCGCTCCTACGGGTAC
TCGCCGACAAAAGGCATGCTGGAAACCCGCAAATTTCTGGCGGAAAAGGTCAACGCCCGGGGGAAGGTCCAGATCACACC
GGAGGACATCCTGTTCTTCAACGGCCTGGGGGACGCCATCGCCCGGTCCTACAGCGCGATCCGCGTCGACGCCCGCATCA
TCATGCCGGAGCCGACCTACTCCACCCATTTTCTGGCCGAAGTCCTGCACGCCTCCTTCCCGCCCAACACCTACCGGATG
AATCCCTACCGGGACTGGCATCCGGACATCCACGAACTGGAGCACAAGGTCCGAAGCTACGGGTCCATCGTGGGCATCCT
GGTGATCAATCCCGATAACCCCACCGGGTTCGTCTATTCCGAGGAATCCCTGCGGAAAATCGTGGACATCGCCCGAAAAT
ACGATCTTTTTCTCGTCTTTGACGAGACGTACCACAACATTGTCTACAACGGCAGGGAAACCCTTCCCCTGTCGGACATC
ATCGGCGACGTGCCGGGTGTCAGCCTGAAGGGAATCTCCAAGGAATTCCCCTGGCCGGGTTCGCGATGCGGCTGGATGGA
GATCTACAACGCCGACAAGGATGAATGCTTCGCCCGCTATATGAAGGCCATCCTGGATCAGAAAATGTCCGAGGTCTGCT
CAACCACGCTGCCCCAGATCGCTATCCCGAAGATCATGAGCCATCCGGAATACAAGAATTACCTCAACCAGCGGCTCCAC
CACTACGAACGGTTCTCCAACATCGCCTACGAGCTGCTGAAGGACGTCCCCTACATCATGGTGAACAAGCCCAACGGCGC
TTTTTACCTGAGCATCGTCTTCAACGAAGCAGTCCTGAACGGCAGGCAGCGCCTGAAAATCGAACACCCCGAAATCCGCC
GGTACATCGAAAGCATCATGACGGAGTCGATCGAATACGACAAGCGCTTTGTCTACTATCTCCTCGGCGCCACCGGCATC
TGCGTGGTTCCTCTGACGTCCTTCTTTACCGCCCTCCCCGGATTCCGGATGACCCTCCTGAGCCAGGATGAGGCCAAGTT
CGAGTACACCGTGCGCACAATCGCCGAAAAGGTCGTGGAATATATCGAATCAGGAAACCAAGGCTGA

Upstream 100 bases:

>100_bases
AATATGCAATGAAGTCATCAACTAAAGTTGGGGAGGGCGTCACAAAAAAAATGTGGATATTTTCTTGGAAGTATAATAGT
CATCAAGTTTCTATCTCTGA

Downstream 100 bases:

>100_bases
AAAAGAGGGACAGCGCCCTTTTTCGTGTTCAATGTTCAAGGTTCGATGTTCGACGTTCAAGGTTTCGGGTTCGAGGTTAT
TGTGAAAAACAAGGGGGGTT

Product: aminotransferase

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MRTTESQRGVCLMRLDIAKGGTGLVYEIRNIVNVANRLKEYGIDVIWENIGDPIQKGEQLPGWMKETLTEIMQDDRSYGY
SPTKGMLETRKFLAEKVNARGKVQITPEDILFFNGLGDAIARSYSAIRVDARIIMPEPTYSTHFLAEVLHASFPPNTYRM
NPYRDWHPDIHELEHKVRSYGSIVGILVINPDNPTGFVYSEESLRKIVDIARKYDLFLVFDETYHNIVYNGRETLPLSDI
IGDVPGVSLKGISKEFPWPGSRCGWMEIYNADKDECFARYMKAILDQKMSEVCSTTLPQIAIPKIMSHPEYKNYLNQRLH
HYERFSNIAYELLKDVPYIMVNKPNGAFYLSIVFNEAVLNGRQRLKIEHPEIRRYIESIMTESIEYDKRFVYYLLGATGI
CVVPLTSFFTALPGFRMTLLSQDEAKFEYTVRTIAEKVVEYIESGNQG

Sequences:

>Translated_448_residues
MRTTESQRGVCLMRLDIAKGGTGLVYEIRNIVNVANRLKEYGIDVIWENIGDPIQKGEQLPGWMKETLTEIMQDDRSYGY
SPTKGMLETRKFLAEKVNARGKVQITPEDILFFNGLGDAIARSYSAIRVDARIIMPEPTYSTHFLAEVLHASFPPNTYRM
NPYRDWHPDIHELEHKVRSYGSIVGILVINPDNPTGFVYSEESLRKIVDIARKYDLFLVFDETYHNIVYNGRETLPLSDI
IGDVPGVSLKGISKEFPWPGSRCGWMEIYNADKDECFARYMKAILDQKMSEVCSTTLPQIAIPKIMSHPEYKNYLNQRLH
HYERFSNIAYELLKDVPYIMVNKPNGAFYLSIVFNEAVLNGRQRLKIEHPEIRRYIESIMTESIEYDKRFVYYLLGATGI
CVVPLTSFFTALPGFRMTLLSQDEAKFEYTVRTIAEKVVEYIESGNQG
>Mature_448_residues
MRTTESQRGVCLMRLDIAKGGTGLVYEIRNIVNVANRLKEYGIDVIWENIGDPIQKGEQLPGWMKETLTEIMQDDRSYGY
SPTKGMLETRKFLAEKVNARGKVQITPEDILFFNGLGDAIARSYSAIRVDARIIMPEPTYSTHFLAEVLHASFPPNTYRM
NPYRDWHPDIHELEHKVRSYGSIVGILVINPDNPTGFVYSEESLRKIVDIARKYDLFLVFDETYHNIVYNGRETLPLSDI
IGDVPGVSLKGISKEFPWPGSRCGWMEIYNADKDECFARYMKAILDQKMSEVCSTTLPQIAIPKIMSHPEYKNYLNQRLH
HYERFSNIAYELLKDVPYIMVNKPNGAFYLSIVFNEAVLNGRQRLKIEHPEIRRYIESIMTESIEYDKRFVYYLLGATGI
CVVPLTSFFTALPGFRMTLLSQDEAKFEYTVRTIAEKVVEYIESGNQG

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=332, Percent_Identity=25.9036144578313, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI4885351, Length=425, Percent_Identity=23.5294117647059, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI1788627, Length=331, Percent_Identity=30.5135951661631, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1788722, Length=247, Percent_Identity=26.3157894736842, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17567663, Length=325, Percent_Identity=30.4615384615385, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71981209, Length=441, Percent_Identity=24.4897959183673, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320317, Length=379, Percent_Identity=28.4960422163588, Blast_Score=104, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6323118, Length=379, Percent_Identity=25.5936675461741, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI18859735, Length=420, Percent_Identity=25.2380952380952, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI45551451, Length=375, Percent_Identity=24.8, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24641770, Length=375, Percent_Identity=24.8, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24641760, Length=375, Percent_Identity=24.8, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24641768, Length=375, Percent_Identity=24.8, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24641766, Length=375, Percent_Identity=24.8, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24641764, Length=375, Percent_Identity=24.8, Blast_Score=84, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 51577; Mature: 51577

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTTESQRGVCLMRLDIAKGGTGLVYEIRNIVNVANRLKEYGIDVIWENIGDPIQKGEQL
CCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHCCCCC
PGWMKETLTEIMQDDRSYGYSPTKGMLETRKFLAEKVNARGKVQITPEDILFFNGLGDAI
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEECHHHEEEECCCCHHH
ARSYSAIRVDARIIMPEPTYSTHFLAEVLHASFPPNTYRMNPYRDWHPDIHELEHKVRSY
HHCHHHEEEEEEEEECCCCCHHHHHHHHHHCCCCCCCEECCCCCCCCCCHHHHHHHHHHC
GSIVGILVINPDNPTGFVYSEESLRKIVDIARKYDLFLVFDETYHNIVYNGRETLPLSDI
CCEEEEEEECCCCCCCEEECHHHHHHHHHHHHHCCEEEEECCCHHHHEECCCCCCCHHHH
IGDVPGVSLKGISKEFPWPGSRCGWMEIYNADKDECFARYMKAILDQKMSEVCSTTLPQI
HCCCCCCEECCCCCCCCCCCCCCCHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
AIPKIMSHPEYKNYLNQRLHHYERFSNIAYELLKDVPYIMVNKPNGAFYLSIVFNEAVLN
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEEEHHHHHC
GRQRLKIEHPEIRRYIESIMTESIEYDKRFVYYLLGATGICVVPLTSFFTALPGFRMTLL
CCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHCCCCEEEEE
SQDEAKFEYTVRTIAEKVVEYIESGNQG
CCCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRTTESQRGVCLMRLDIAKGGTGLVYEIRNIVNVANRLKEYGIDVIWENIGDPIQKGEQL
CCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHCCCCC
PGWMKETLTEIMQDDRSYGYSPTKGMLETRKFLAEKVNARGKVQITPEDILFFNGLGDAI
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEECHHHEEEECCCCHHH
ARSYSAIRVDARIIMPEPTYSTHFLAEVLHASFPPNTYRMNPYRDWHPDIHELEHKVRSY
HHCHHHEEEEEEEEECCCCCHHHHHHHHHHCCCCCCCEECCCCCCCCCCHHHHHHHHHHC
GSIVGILVINPDNPTGFVYSEESLRKIVDIARKYDLFLVFDETYHNIVYNGRETLPLSDI
CCEEEEEEECCCCCCCEEECHHHHHHHHHHHHHCCEEEEECCCHHHHEECCCCCCCHHHH
IGDVPGVSLKGISKEFPWPGSRCGWMEIYNADKDECFARYMKAILDQKMSEVCSTTLPQI
HCCCCCCEECCCCCCCCCCCCCCCHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
AIPKIMSHPEYKNYLNQRLHHYERFSNIAYELLKDVPYIMVNKPNGAFYLSIVFNEAVLN
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEEEHHHHHC
GRQRLKIEHPEIRRYIESIMTESIEYDKRFVYYLLGATGICVVPLTSFFTALPGFRMTLL
CCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHCCCCEEEEE
SQDEAKFEYTVRTIAEKVVEYIESGNQG
CCCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]