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The map label for this gene is engA

Identifier: 85860147

GI number: 85860147

Start: 2351845

End: 2353188

Strand: Direct

Name: engA

Synonym: SYN_00791

Alternate gene names: 85860147

Gene position: 2351845-2353188 (Clockwise)

Preceding gene: 85860146

Following gene: 85860149

Centisome position: 73.97

GC content: 54.32

Gene sequence:

>1344_bases
TTGGAAAGAAACACGATAGTTGCCATTGTTGGACGACCCAACGTGGGCAAATCAACATTGTTCAACCGACTGTCACAGAA
AAGCAAGGCAATCGTCATTGACGTGCCGGGAGCCACGCGGGACCGGAATTATGCGGACTGCACCTGGCATGGACGACGAT
ACACCCTCATCGACACGGGAGGATTTGAACCGGCATCCACGGAAACCATTCTCATTCAGATGAGGGAACAGACTCATCTG
GCCATTGAAGAAGCCGACATCATCATCTTCCTGATGGATGGACGGGACGGTCTGACCCCTGCCGATATTGAAATCGTGCA
ATTGTTGCGCGAAGGAGGGAAAAAGGTTTTTTATGCCGTCAACAAGGTGGACGGTCCCCGGCATGAGGGCCTCCTGCCGG
AATTCTACCGTCTTGGAGTCTCCCGTATCCATGACATCTCAGCCCAGCATGGCCTGGGCATCGATGAACTGATGGAGGAC
CTGTCGGCCTGTCTCCCTGAGGAAGCAGCGTCTGCCGGCGAAGAAGGAGAAGAGGAGGACCGGATCCGGATCGCCCTGAT
CGGCAAGCCCAATGTGGGCAAGTCATCACTGCTCAATAAAATCCTGGGCTACGAACGGACCATCGCCAATCCCACGCCGG
GCACCACGCGGGATGCCATCGACACCCCCTTTGAATTCGACGGTCACAGGTATCTGCTGATCGACACAGCCGGCATCCGC
AAAAAGAGCCGGATCAGCCTGAGTCTCGAAAAATACAGCGTCATTCAGGCACTGAAGACCCTGGACCGATGTGATATCGC
CCTGCTGCTCATCGACGCGGAAGAGGGAATCACCGATCAGGACACCAAAATCGCCGGGCTGGCCTTTGAAAAGGGCAGAG
CCGTCATTATCGTGGTGAACAAATGGGACCTCGTCGCCAAGGACAACAGCACGGTGGGACGTTACGTGCGGGACATTAAG
GATCGGCTGAAATTCATGGATTTTTCCCCCATCATCTTTGTCTCCGCCCTGTCCGGTCAGCGGGTGACGCGGATTTTCGC
TCTGGTGCAGGAGGTTTATCGTCAGTACACGACCCGGATCAGCACGGGGGAGCTGAACCGGAAAGTGATGGAGATTGTGT
CCAAAAATCCGCCGCCCCAGTATCAGCAAAAGGCGCATCCCTTCAATTATGTTACCCAGGTGTCCATCAAGCCTCCCACC
TTTGCCTTTTTTGTCGGCAAGCCTGCTGAAATCCATTTTTCCTACGAACGTTACCTGATTAACTCCCTGAGGGAAGCCTT
AGGTTTCACTACGGTTCCCATAAGGCTCGTCTTCCGGAGAAAGCATCGTAATATCGGTTCATGA

Upstream 100 bases:

>100_bases
TTCCCGTCCGTTTCGTTCAGCAAGAAGCCCTGTTTCACGGGACATTCCCCTTCCACCCTTAACAGGAACTGCTGGATGAA
TCGTTCATAAGGAGTATTTT

Downstream 100 bases:

>100_bases
TTACCGTTCCGGATCAGGAATGATCTCAAGACGCCCGGCCTGTTTTCATCTTGACACCCCCTGACTTTTTAAGTAGTCCG
TCCTGAAAAATAGGATGTGA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MERNTIVAIVGRPNVGKSTLFNRLSQKSKAIVIDVPGATRDRNYADCTWHGRRYTLIDTGGFEPASTETILIQMREQTHL
AIEEADIIIFLMDGRDGLTPADIEIVQLLREGGKKVFYAVNKVDGPRHEGLLPEFYRLGVSRIHDISAQHGLGIDELMED
LSACLPEEAASAGEEGEEEDRIRIALIGKPNVGKSSLLNKILGYERTIANPTPGTTRDAIDTPFEFDGHRYLLIDTAGIR
KKSRISLSLEKYSVIQALKTLDRCDIALLLIDAEEGITDQDTKIAGLAFEKGRAVIIVVNKWDLVAKDNSTVGRYVRDIK
DRLKFMDFSPIIFVSALSGQRVTRIFALVQEVYRQYTTRISTGELNRKVMEIVSKNPPPQYQQKAHPFNYVTQVSIKPPT
FAFFVGKPAEIHFSYERYLINSLREALGFTTVPIRLVFRRKHRNIGS

Sequences:

>Translated_447_residues
MERNTIVAIVGRPNVGKSTLFNRLSQKSKAIVIDVPGATRDRNYADCTWHGRRYTLIDTGGFEPASTETILIQMREQTHL
AIEEADIIIFLMDGRDGLTPADIEIVQLLREGGKKVFYAVNKVDGPRHEGLLPEFYRLGVSRIHDISAQHGLGIDELMED
LSACLPEEAASAGEEGEEEDRIRIALIGKPNVGKSSLLNKILGYERTIANPTPGTTRDAIDTPFEFDGHRYLLIDTAGIR
KKSRISLSLEKYSVIQALKTLDRCDIALLLIDAEEGITDQDTKIAGLAFEKGRAVIIVVNKWDLVAKDNSTVGRYVRDIK
DRLKFMDFSPIIFVSALSGQRVTRIFALVQEVYRQYTTRISTGELNRKVMEIVSKNPPPQYQQKAHPFNYVTQVSIKPPT
FAFFVGKPAEIHFSYERYLINSLREALGFTTVPIRLVFRRKHRNIGS
>Mature_447_residues
MERNTIVAIVGRPNVGKSTLFNRLSQKSKAIVIDVPGATRDRNYADCTWHGRRYTLIDTGGFEPASTETILIQMREQTHL
AIEEADIIIFLMDGRDGLTPADIEIVQLLREGGKKVFYAVNKVDGPRHEGLLPEFYRLGVSRIHDISAQHGLGIDELMED
LSACLPEEAASAGEEGEEEDRIRIALIGKPNVGKSSLLNKILGYERTIANPTPGTTRDAIDTPFEFDGHRYLLIDTAGIR
KKSRISLSLEKYSVIQALKTLDRCDIALLLIDAEEGITDQDTKIAGLAFEKGRAVIIVVNKWDLVAKDNSTVGRYVRDIK
DRLKFMDFSPIIFVSALSGQRVTRIFALVQEVYRQYTTRISTGELNRKVMEIVSKNPPPQYQQKAHPFNYVTQVSIKPPT
FAFFVGKPAEIHFSYERYLINSLREALGFTTVPIRLVFRRKHRNIGS

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Homo sapiens, GI193082991, Length=134, Percent_Identity=31.3432835820896, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI193082988, Length=134, Percent_Identity=31.3432835820896, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI87082120, Length=459, Percent_Identity=39.4335511982571, Blast_Score=328, Evalue=3e-91,
Organism=Escherichia coli, GI1788919, Length=166, Percent_Identity=34.3373493975904, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI2367268, Length=99, Percent_Identity=41.4141414141414, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17507259, Length=171, Percent_Identity=32.1637426900585, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=252, Percent_Identity=28.1746031746032, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI45550813, Length=95, Percent_Identity=40, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 50291; Mature: 50291

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERNTIVAIVGRPNVGKSTLFNRLSQKSKAIVIDVPGATRDRNYADCTWHGRRYTLIDTG
CCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEECCCEEEEEECC
GFEPASTETILIQMREQTHLAIEEADIIIFLMDGRDGLTPADIEIVQLLREGGKKVFYAV
CCCCCCCCEEEEEEECCCEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEE
NKVDGPRHEGLLPEFYRLGVSRIHDISAQHGLGIDELMEDLSACLPEEAASAGEEGEEED
ECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHCCCCCCCCCC
RIRIALIGKPNVGKSSLLNKILGYERTIANPTPGTTRDAIDTPFEFDGHRYLLIDTAGIR
CEEEEEEECCCCCHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCEECCEEEEEEECCCCC
KKSRISLSLEKYSVIQALKTLDRCDIALLLIDAEEGITDQDTKIAGLAFEKGRAVIIVVN
CCCEEEEEHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEEEECCCEEEEEEE
KWDLVAKDNSTVGRYVRDIKDRLKFMDFSPIIFVSALSGQRVTRIFALVQEVYRQYTTRI
CCEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCC
STGELNRKVMEIVSKNPPPQYQQKAHPFNYVTQVSIKPPTFAFFVGKPAEIHFSYERYLI
CCCHHHHHHHHHHHCCCCCCHHHCCCCCCEEEEEEECCCEEEEEECCCEEEEEHHHHHHH
NSLREALGFTTVPIRLVFRRKHRNIGS
HHHHHHHCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MERNTIVAIVGRPNVGKSTLFNRLSQKSKAIVIDVPGATRDRNYADCTWHGRRYTLIDTG
CCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEECCCEEEEEECC
GFEPASTETILIQMREQTHLAIEEADIIIFLMDGRDGLTPADIEIVQLLREGGKKVFYAV
CCCCCCCCEEEEEEECCCEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEE
NKVDGPRHEGLLPEFYRLGVSRIHDISAQHGLGIDELMEDLSACLPEEAASAGEEGEEED
ECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHCCCCCCCCCC
RIRIALIGKPNVGKSSLLNKILGYERTIANPTPGTTRDAIDTPFEFDGHRYLLIDTAGIR
CEEEEEEECCCCCHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCEECCEEEEEEECCCCC
KKSRISLSLEKYSVIQALKTLDRCDIALLLIDAEEGITDQDTKIAGLAFEKGRAVIIVVN
CCCEEEEEHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEEEECCCEEEEEEE
KWDLVAKDNSTVGRYVRDIKDRLKFMDFSPIIFVSALSGQRVTRIFALVQEVYRQYTTRI
CCEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCC
STGELNRKVMEIVSKNPPPQYQQKAHPFNYVTQVSIKPPTFAFFVGKPAEIHFSYERYLI
CCCHHHHHHHHHHHCCCCCCHHHCCCCCCEEEEEEECCCEEEEEECCCEEEEEHHHHHHH
NSLREALGFTTVPIRLVFRRKHRNIGS
HHHHHHHCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA