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The map label for this gene is era

Identifier: 85860146

GI number: 85860146

Start: 2350712

End: 2351632

Strand: Direct

Name: era

Synonym: SYN_00792

Alternate gene names: 85860146

Gene position: 2350712-2351632 (Clockwise)

Preceding gene: 85860145

Following gene: 85860147

Centisome position: 73.94

GC content: 51.68

Gene sequence:

>921_bases
ATGGACAGAAAAAGTTCAGGAGGTTGCTCCATCATGTTCAAGTCCGGTTTCATCGGAATCATCGGCAGACCCAATGTAGG
AAAATCAACACTTCTCAACGGTATTCTGGGCGAGAAACTGGCCATCATCACCCACAAGCCCCAAACCACACGGAATCGGA
TCATGGGGATAAGAAACGCGGACAACGCCCAGTTTATCTTTGTGGATACCCCGGGGATTCATTCGGCCAGCACTCCCCTG
AACCGGCTCATGGTCCGCACGGCCACGGAAACCTTCACCGATTCCGATATCCTTCTTCTCGTTGTGGAAGCGGGACAGGC
GGTCCACCCGGAAGACCTTCCCATTATCGAGTCCCTGAAAGAGAGCGGGACCATCTCCTTTCTGATTCTCAACAAAATCG
ATCTGATCCGGAAGGAGCAGCTTCTGCCGCTGATGGACGCCTACCGCAATCTGCATTCCTTTGCCGAACTGATCCCGATT
TCCGCTTTGACGGGAGAGGGAATTCCCCTTCTTCTGGATGAACTCTGGAAATACCTGCCTGAAGGCCCCCAATATTTTCC
CGACGACATGATGACCGATCAGAGCGAACGATTTCTTGCCGCGGAGATCATCCGGGAAAAGATTCTCCTGCTCACCCACA
AGGAAATCCCCTATTCTTCCGCCGTCGTCGTCGATGCCTTCAAGGAGGATGAAGCCAGAAATCTCATCCGAATTTCGGCC
ACGATCAACGTGGAAAAGGAATCACAAAAGGGAATCATCATCGGCAAAAAGGGAACCATGCTGAAAGAGATCGGTACAAG
GGCACGGGTGGATATGGAAAAGTTCTTCGCGACCCGGATTTTCCTGGAATTGTTTGTGCGGGTCAGAAAAGACTGGACAA
AGGATCCCAGAATGCTGCGGGAATTCGGGTATAACGAGTAG

Upstream 100 bases:

>100_bases
CAAGTCCGGGAAAATTTTTTAATTTTGCCTGCCCGGATTATCGCGCGATCCTGTATGGCCATCGTATTGTTCCGGTTGCA
GCTCCGGTGAAATCCATGTT

Downstream 100 bases:

>100_bases
GCATGATTTCACGGGAAAACTTTTTCCTTGAAATGGATAAAAAGTTGTGACAGACAGCCGCTTACTCAAAGAGTCCGGAA
ACGCAGATCAATATCAAAAT

Product: GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MDRKSSGGCSIMFKSGFIGIIGRPNVGKSTLLNGILGEKLAIITHKPQTTRNRIMGIRNADNAQFIFVDTPGIHSASTPL
NRLMVRTATETFTDSDILLLVVEAGQAVHPEDLPIIESLKESGTISFLILNKIDLIRKEQLLPLMDAYRNLHSFAELIPI
SALTGEGIPLLLDELWKYLPEGPQYFPDDMMTDQSERFLAAEIIREKILLLTHKEIPYSSAVVVDAFKEDEARNLIRISA
TINVEKESQKGIIIGKKGTMLKEIGTRARVDMEKFFATRIFLELFVRVRKDWTKDPRMLREFGYNE

Sequences:

>Translated_306_residues
MDRKSSGGCSIMFKSGFIGIIGRPNVGKSTLLNGILGEKLAIITHKPQTTRNRIMGIRNADNAQFIFVDTPGIHSASTPL
NRLMVRTATETFTDSDILLLVVEAGQAVHPEDLPIIESLKESGTISFLILNKIDLIRKEQLLPLMDAYRNLHSFAELIPI
SALTGEGIPLLLDELWKYLPEGPQYFPDDMMTDQSERFLAAEIIREKILLLTHKEIPYSSAVVVDAFKEDEARNLIRISA
TINVEKESQKGIIIGKKGTMLKEIGTRARVDMEKFFATRIFLELFVRVRKDWTKDPRMLREFGYNE
>Mature_306_residues
MDRKSSGGCSIMFKSGFIGIIGRPNVGKSTLLNGILGEKLAIITHKPQTTRNRIMGIRNADNAQFIFVDTPGIHSASTPL
NRLMVRTATETFTDSDILLLVVEAGQAVHPEDLPIIESLKESGTISFLILNKIDLIRKEQLLPLMDAYRNLHSFAELIPI
SALTGEGIPLLLDELWKYLPEGPQYFPDDMMTDQSERFLAAEIIREKILLLTHKEIPYSSAVVVDAFKEDEARNLIRISA
TINVEKESQKGIIIGKKGTMLKEIGTRARVDMEKFFATRIFLELFVRVRKDWTKDPRMLREFGYNE

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain

Homologues:

Organism=Escherichia coli, GI1788919, Length=292, Percent_Identity=42.4657534246575, Blast_Score=234, Evalue=7e-63,
Organism=Escherichia coli, GI87082120, Length=164, Percent_Identity=30.4878048780488, Blast_Score=83, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6323665, Length=195, Percent_Identity=28.2051282051282, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ERA_SYNAS (Q2LVR8)

Other databases:

- EMBL:   CP000252
- RefSeq:   YP_462348.1
- ProteinModelPortal:   Q2LVR8
- SMR:   Q2LVR8
- STRING:   Q2LVR8
- GeneID:   3883562
- GenomeReviews:   CP000252_GR
- KEGG:   sat:SYN_00792
- NMPDR:   fig|56780.10.peg.2289
- eggNOG:   COG1159
- HOGENOM:   HBG561652
- OMA:   AKDWQRD
- PhylomeDB:   Q2LVR8
- BioCyc:   SACI56780:SYN_00792-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00367
- InterPro:   IPR003593
- InterPro:   IPR005662
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- SMART:   SM00382
- TIGRFAMs:   TIGR00436
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1; SSF54814 KH_prok

EC number: NA

Molecular weight: Translated: 34549; Mature: 34549

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRKSSGGCSIMFKSGFIGIIGRPNVGKSTLLNGILGEKLAIITHKPQTTRNRIMGIRNA
CCCCCCCCEEEEEECCCEEEEECCCCCHHHHHHHHHCCEEEEEEECCCHHHHHEEECCCC
DNAQFIFVDTPGIHSASTPLNRLMVRTATETFTDSDILLLVVEAGQAVHPEDLPIIESLK
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHHHHH
ESGTISFLILNKIDLIRKEQLLPLMDAYRNLHSFAELIPISALTGEGIPLLLDELWKYLP
HCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
EGPQYFPDDMMTDQSERFLAAEIIREKILLLTHKEIPYSSAVVVDAFKEDEARNLIRISA
CCCCCCCCHHCCCCHHHHHHHHHHHHHHHHEEECCCCCCCEEEEEECCCCCCCCEEEEEE
TINVEKESQKGIIIGKKGTMLKEIGTRARVDMEKFFATRIFLELFVRVRKDWTKDPRMLR
EEEEECCCCCCEEEECCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
EFGYNE
HCCCCC
>Mature Secondary Structure
MDRKSSGGCSIMFKSGFIGIIGRPNVGKSTLLNGILGEKLAIITHKPQTTRNRIMGIRNA
CCCCCCCCEEEEEECCCEEEEECCCCCHHHHHHHHHCCEEEEEEECCCHHHHHEEECCCC
DNAQFIFVDTPGIHSASTPLNRLMVRTATETFTDSDILLLVVEAGQAVHPEDLPIIESLK
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHHHHH
ESGTISFLILNKIDLIRKEQLLPLMDAYRNLHSFAELIPISALTGEGIPLLLDELWKYLP
HCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
EGPQYFPDDMMTDQSERFLAAEIIREKILLLTHKEIPYSSAVVVDAFKEDEARNLIRISA
CCCCCCCCHHCCCCHHHHHHHHHHHHHHHHEEECCCCCCCEEEEEECCCCCCCCEEEEEE
TINVEKESQKGIIIGKKGTMLKEIGTRARVDMEKFFATRIFLELFVRVRKDWTKDPRMLR
EEEEECCCCCCEEEECCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
EFGYNE
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA