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The map label for this gene is aspB [H]

Identifier: 85859444

GI number: 85859444

Start: 1647510

End: 1648712

Strand: Direct

Name: aspB [H]

Synonym: SYN_00908

Alternate gene names: 85859444

Gene position: 1647510-1648712 (Clockwise)

Preceding gene: 85859443

Following gene: 85859445

Centisome position: 51.82

GC content: 49.04

Gene sequence:

>1203_bases
ATGATGATTATGAAACTGGCATCAAGAGTATCTATGATAAAACCTTCACCGACGCTGGTCATAACCGCAAAAGCCGGCGC
CCTGCGTGCTGAGGGGCGGGATATCATCGATTTCGGGGCAGGGGAACCGGATTTCAATACCCCCGATCATATTAAGATGG
CTGCCATCCATGCGGTGGAATCCAATTTTACCCGCTACACGCCTGTCGGAGGAATCGATGAACTGAAAGACGCAATCATC
GGCAAGCTCAAAAGGGATAATTATCTATCCTACAGACGATCGGAAATCATTGTCTCCTGCGGAGCCAAGCATACGCTCTT
CAATCTTTCCCAGGCTCTTTTTGACGAAGGGGATGAGGTCATCATTCCAAGTCCCTACTGGGTTTCCTATCCGGATATCG
TTCTTTTGACGGGCGCCCGGCCTGTAATCGTGGAAACCAGAGAGGAAAACGGCTTTAAAATGACGCCCGCTGAACTGGAA
GCGGCGATCACTAAAAACAGCAAAGCCGTCATAATCAACAGTCCATCAAACCCGACGGGCTGCGTCTACTCGAAAGAAGA
ACTTGCCGCCCTGGCTGAGGTGGTACTCCATCATCAGCTGATTGTCGTTTCCGATGATATTTATGAAAAAATTATCTATG
ATGATTTTCCTTTCTGGAACATAACCGCCGTCAACCCGTCATTGAAAGACCTGACTGTCGTCGTCAACGGGATTTCAAAG
GCCTATGCCATGACCGGATGGAGAATCGGTTATGCCGCAGCTCCCGAATTTCTTATCGCGGCCATGGCAAAGATTCAGAG
TCAGAGTACATCCAATCCCTCCTCGATTTCCCAGAAAGCTGCAGTGGAAGCTCTGACCGGCGATCAGCAGATTATTGCCG
GGATGGTGGCAGAATTTCAAAAACGACGTGATTACGTGGTTTCAACACTGGAGAGTTTCGACGGCATTTCGTGCCTGGAG
CCCCAAGGAGCGTTTTACGTCTTTCCCAATGTGGAGTCCTTGTATGGATTGCGCTGCGGAAATAAGAAAATTTTAGATTC
GACAACACTGGCGGAATATCTTCTTGATGAAGCCGAGGTTGCCGTAGTGCCGGGCATTGCATTTGGGAACGACCGGCATA
TCCGTATTTCCTACGCGACATCCATGGCTCTTATTGAAAAAGGGCTGGAACGAATACGGATGGCCTTGAAACGGTTAAGT
TGA

Upstream 100 bases:

>100_bases
TCAAAGAGGCCTCCCGCCTTGGAGGCTCTCCGAAAGGTCTTGTACCGGAGGTGGTTTTCAGAAAAATGCAGGAAAAATAT
CCACTAATGAATAAGGGTAA

Downstream 100 bases:

>100_bases
CCATAAATTTGAATGATTAAGTTTAAAAAAATTATAAAATTTTACAGGTAAACATGCCATGGGCGGATTATTCGGGGTTG
TTTCCAAGGGAAACTGCATA

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MMIMKLASRVSMIKPSPTLVITAKAGALRAEGRDIIDFGAGEPDFNTPDHIKMAAIHAVESNFTRYTPVGGIDELKDAII
GKLKRDNYLSYRRSEIIVSCGAKHTLFNLSQALFDEGDEVIIPSPYWVSYPDIVLLTGARPVIVETREENGFKMTPAELE
AAITKNSKAVIINSPSNPTGCVYSKEELAALAEVVLHHQLIVVSDDIYEKIIYDDFPFWNITAVNPSLKDLTVVVNGISK
AYAMTGWRIGYAAAPEFLIAAMAKIQSQSTSNPSSISQKAAVEALTGDQQIIAGMVAEFQKRRDYVVSTLESFDGISCLE
PQGAFYVFPNVESLYGLRCGNKKILDSTTLAEYLLDEAEVAVVPGIAFGNDRHIRISYATSMALIEKGLERIRMALKRLS

Sequences:

>Translated_400_residues
MMIMKLASRVSMIKPSPTLVITAKAGALRAEGRDIIDFGAGEPDFNTPDHIKMAAIHAVESNFTRYTPVGGIDELKDAII
GKLKRDNYLSYRRSEIIVSCGAKHTLFNLSQALFDEGDEVIIPSPYWVSYPDIVLLTGARPVIVETREENGFKMTPAELE
AAITKNSKAVIINSPSNPTGCVYSKEELAALAEVVLHHQLIVVSDDIYEKIIYDDFPFWNITAVNPSLKDLTVVVNGISK
AYAMTGWRIGYAAAPEFLIAAMAKIQSQSTSNPSSISQKAAVEALTGDQQIIAGMVAEFQKRRDYVVSTLESFDGISCLE
PQGAFYVFPNVESLYGLRCGNKKILDSTTLAEYLLDEAEVAVVPGIAFGNDRHIRISYATSMALIEKGLERIRMALKRLS
>Mature_400_residues
MMIMKLASRVSMIKPSPTLVITAKAGALRAEGRDIIDFGAGEPDFNTPDHIKMAAIHAVESNFTRYTPVGGIDELKDAII
GKLKRDNYLSYRRSEIIVSCGAKHTLFNLSQALFDEGDEVIIPSPYWVSYPDIVLLTGARPVIVETREENGFKMTPAELE
AAITKNSKAVIINSPSNPTGCVYSKEELAALAEVVLHHQLIVVSDDIYEKIIYDDFPFWNITAVNPSLKDLTVVVNGISK
AYAMTGWRIGYAAAPEFLIAAMAKIQSQSTSNPSSISQKAAVEALTGDQQIIAGMVAEFQKRRDYVVSTLESFDGISCLE
PQGAFYVFPNVESLYGLRCGNKKILDSTTLAEYLLDEAEVAVVPGIAFGNDRHIRISYATSMALIEKGLERIRMALKRLS

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=327, Percent_Identity=28.1345565749235, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI169881279, Length=327, Percent_Identity=28.1345565749235, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI56713254, Length=321, Percent_Identity=29.595015576324, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI56713256, Length=321, Percent_Identity=29.595015576324, Blast_Score=152, Evalue=7e-37,
Organism=Homo sapiens, GI169881281, Length=397, Percent_Identity=21.4105793450882, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI4507369, Length=306, Percent_Identity=19.9346405228758, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1788722, Length=402, Percent_Identity=32.8358208955224, Blast_Score=161, Evalue=7e-41,
Organism=Escherichia coli, GI1786816, Length=371, Percent_Identity=26.9541778975741, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1788627, Length=359, Percent_Identity=27.0194986072423, Blast_Score=138, Evalue=8e-34,
Organism=Escherichia coli, GI1787909, Length=378, Percent_Identity=20.3703703703704, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71994472, Length=371, Percent_Identity=26.1455525606469, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71994476, Length=371, Percent_Identity=26.1455525606469, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17567369, Length=373, Percent_Identity=26.2734584450402, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17567663, Length=385, Percent_Identity=22.5974025974026, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71981209, Length=347, Percent_Identity=23.342939481268, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6322401, Length=397, Percent_Identity=25.9445843828715, Blast_Score=130, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6323118, Length=370, Percent_Identity=23.5135135135135, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320317, Length=331, Percent_Identity=23.8670694864048, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI28573069, Length=326, Percent_Identity=24.8466257668712, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24646114, Length=326, Percent_Identity=24.8466257668712, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI28573067, Length=326, Percent_Identity=24.8466257668712, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI28573065, Length=326, Percent_Identity=24.8466257668712, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI18859735, Length=384, Percent_Identity=23.6979166666667, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24641770, Length=363, Percent_Identity=23.6914600550964, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24641760, Length=363, Percent_Identity=23.6914600550964, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24641768, Length=363, Percent_Identity=23.6914600550964, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24641766, Length=363, Percent_Identity=23.6914600550964, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24641764, Length=363, Percent_Identity=23.6914600550964, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI45551451, Length=363, Percent_Identity=23.6914600550964, Blast_Score=79, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43880; Mature: 43880

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMIMKLASRVSMIKPSPTLVITAKAGALRAEGRDIIDFGAGEPDFNTPDHIKMAAIHAVE
CHHHHHHHHHHHCCCCCCEEEEECCCCEECCCCCEEECCCCCCCCCCCCCEEHHHHHHHH
SNFTRYTPVGGIDELKDAIIGKLKRDNYLSYRRSEIIVSCGAKHTLFNLSQALFDEGDEV
CCCCEECCCCCHHHHHHHHHHHHCCCCHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCCE
IIPSPYWVSYPDIVLLTGARPVIVETREENGFKMTPAELEAAITKNSKAVIINSPSNPTG
EECCCCEECCCCEEEEECCCEEEEEECCCCCCEECHHHHHHHEECCCCEEEEECCCCCCC
CVYSKEELAALAEVVLHHQLIVVSDDIYEKIIYDDFPFWNITAVNPSLKDLTVVVNGISK
CEECHHHHHHHHHHHHHCEEEEEECHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHH
AYAMTGWRIGYAAAPEFLIAAMAKIQSQSTSNPSSISQKAAVEALTGDQQIIAGMVAEFQ
HHHHCCCEECHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
KRRDYVVSTLESFDGISCLEPQGAFYVFPNVESLYGLRCGNKKILDSTTLAEYLLDEAEV
HHHHHHHHHHHHCCCCEEECCCCCEEECCCHHHHHEECCCCCEECCHHHHHHHHHCCCCE
AVVPGIAFGNDRHIRISYATSMALIEKGLERIRMALKRLS
EEECCEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMIMKLASRVSMIKPSPTLVITAKAGALRAEGRDIIDFGAGEPDFNTPDHIKMAAIHAVE
CHHHHHHHHHHHCCCCCCEEEEECCCCEECCCCCEEECCCCCCCCCCCCCEEHHHHHHHH
SNFTRYTPVGGIDELKDAIIGKLKRDNYLSYRRSEIIVSCGAKHTLFNLSQALFDEGDEV
CCCCEECCCCCHHHHHHHHHHHHCCCCHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCCE
IIPSPYWVSYPDIVLLTGARPVIVETREENGFKMTPAELEAAITKNSKAVIINSPSNPTG
EECCCCEECCCCEEEEECCCEEEEEECCCCCCEECHHHHHHHEECCCCEEEEECCCCCCC
CVYSKEELAALAEVVLHHQLIVVSDDIYEKIIYDDFPFWNITAVNPSLKDLTVVVNGISK
CEECHHHHHHHHHHHHHCEEEEEECHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHH
AYAMTGWRIGYAAAPEFLIAAMAKIQSQSTSNPSSISQKAAVEALTGDQQIIAGMVAEFQ
HHHHCCCEECHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
KRRDYVVSTLESFDGISCLEPQGAFYVFPNVESLYGLRCGNKKILDSTTLAEYLLDEAEV
HHHHHHHHHHHHCCCCEEECCCCCEEECCCHHHHHEECCCCCEECCHHHHHHHHHCCCCE
AVVPGIAFGNDRHIRISYATSMALIEKGLERIRMALKRLS
EEECCEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]