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The map label for this gene is ttdA [C]

Identifier: 85857926

GI number: 85857926

Start: 82905

End: 83759

Strand: Direct

Name: ttdA [C]

Synonym: SYN_00159

Alternate gene names: 85857926

Gene position: 82905-83759 (Clockwise)

Preceding gene: 85857925

Following gene: 85857927

Centisome position: 2.61

GC content: 60.47

Gene sequence:

>855_bases
ATGATGAGCCGAATCAGAGAAATTTTCGTGGAGACTGTCACGGATACCGTGCGGGAGCTTTTCATCGCTGCAAACCGCGA
ACTGAGCCGCGACGTGCTGGAAGCTCTGGCAAGGGCGGCGGAAGAGGAAGTGTCGCCCCTGGGACGTTACGCCCTGGAAA
AAATCCTCGAAAATACGGAAGTGGCCAGAGATGATAATATGCCTCTCTGCCAGGATACGGGCCTGGCGGTAGTTTTCGTG
GAAATGGGCCAGGATGTGCACATCGTGGGCGGCGATTTCAATGAAGCCGTTCAGGAGGGCGTCCGACAGGCCTACCGGGA
TGGGTATCTCCGCAAATCCCTTTGTGACCCCCTGTCGCGGCGGAATACGGGCGACAATACTCCGGCGGTGATTTTTACCG
AACTGGTTCCGGGCGACCAGCTCAAGCTGAGTGCGATGCCCAAGGGCGGCGGCAGTGAAAACATGAGCGGCAGTGTCATG
CTGACCCCGGCTGTGGGTGAGGCCGGGATTCGGGCTCATGTTGTGGACTGTGTCCGCAGAGCCGGTTCCAATCCCTGTCC
GCCGGTCGTTGTAGGGGTGGGCATCGGCGGCTCTCTGGAGATGTCCGCCGTTCTGGCGAAAAAGGCCCTGCTCCGGCCGC
TGGGAACGGCCAATGTCCGGGACGAACGTCTGGCTGCCATGGAGCGGGAACTACTGACGGAAATCAACCGGCTGGGAATC
GGGCCGCAGGGGTATGGGGGGCGTGTGACCGCCCTGGCCGTCCATGTGGAAATGATGCCCTGCCATATCGCCAGTCTGCC
CGTTACTGTCAACATCCAGTGTCACGTGGCTCGGCACCGGGAGGCGGTGATTTAA

Upstream 100 bases:

>100_bases
GATCTCCGGTATATGGATCGGATGACCCTGTCCAAATCGCTGGAATTCCGCCGGGGCATGGAGAAAGAGCCGTGAGGCCT
TCAGGAAAGTCGATATCGGA

Downstream 100 bases:

>100_bases
TGATGAGCGAACCGATCCGTCTGGAAACACCCTTAAATGAGGATCTGTGCAGGCGTCTGTCTGTGGGCGACCGGGTTCTT
CTCAACGGAGTCGTCTATAC

Product: fumarate hydratase

Products: NA

Alternate protein names: Fumarase [H]

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MMSRIREIFVETVTDTVRELFIAANRELSRDVLEALARAAEEEVSPLGRYALEKILENTEVARDDNMPLCQDTGLAVVFV
EMGQDVHIVGGDFNEAVQEGVRQAYRDGYLRKSLCDPLSRRNTGDNTPAVIFTELVPGDQLKLSAMPKGGGSENMSGSVM
LTPAVGEAGIRAHVVDCVRRAGSNPCPPVVVGVGIGGSLEMSAVLAKKALLRPLGTANVRDERLAAMERELLTEINRLGI
GPQGYGGRVTALAVHVEMMPCHIASLPVTVNIQCHVARHREAVI

Sequences:

>Translated_284_residues
MMSRIREIFVETVTDTVRELFIAANRELSRDVLEALARAAEEEVSPLGRYALEKILENTEVARDDNMPLCQDTGLAVVFV
EMGQDVHIVGGDFNEAVQEGVRQAYRDGYLRKSLCDPLSRRNTGDNTPAVIFTELVPGDQLKLSAMPKGGGSENMSGSVM
LTPAVGEAGIRAHVVDCVRRAGSNPCPPVVVGVGIGGSLEMSAVLAKKALLRPLGTANVRDERLAAMERELLTEINRLGI
GPQGYGGRVTALAVHVEMMPCHIASLPVTVNIQCHVARHREAVI
>Mature_284_residues
MMSRIREIFVETVTDTVRELFIAANRELSRDVLEALARAAEEEVSPLGRYALEKILENTEVARDDNMPLCQDTGLAVVFV
EMGQDVHIVGGDFNEAVQEGVRQAYRDGYLRKSLCDPLSRRNTGDNTPAVIFTELVPGDQLKLSAMPKGGGSENMSGSVM
LTPAVGEAGIRAHVVDCVRRAGSNPCPPVVVGVGIGGSLEMSAVLAKKALLRPLGTANVRDERLAAMERELLTEINRLGI
GPQGYGGRVTALAVHVEMMPCHIASLPVTVNIQCHVARHREAVI

Specific function: Unknown

COG id: COG1951

COG function: function code C; Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789442, Length=283, Percent_Identity=31.4487632508834, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1790564, Length=258, Percent_Identity=33.3333333333333, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1787897, Length=258, Percent_Identity=33.3333333333333, Blast_Score=114, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004646 [H]

Pfam domain/function: PF05681 Fumerase [H]

EC number: =4.2.1.2 [H]

Molecular weight: Translated: 30634; Mature: 30634

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSRIREIFVETVTDTVRELFIAANRELSRDVLEALARAAEEEVSPLGRYALEKILENTE
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
VARDDNMPLCQDTGLAVVFVEMGQDVHIVGGDFNEAVQEGVRQAYRDGYLRKSLCDPLSR
HCCCCCCCCCCCCCCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHCHHHH
RNTGDNTPAVIFTELVPGDQLKLSAMPKGGGSENMSGSVMLTPAVGEAGIRAHVVDCVRR
CCCCCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHH
AGSNPCPPVVVGVGIGGSLEMSAVLAKKALLRPLGTANVRDERLAAMERELLTEINRLGI
CCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
GPQGYGGRVTALAVHVEMMPCHIASLPVTVNIQCHVARHREAVI
CCCCCCCEEEEEEEEEEEHHHEEECCCEEEEEEEEEECCCCCCC
>Mature Secondary Structure
MMSRIREIFVETVTDTVRELFIAANRELSRDVLEALARAAEEEVSPLGRYALEKILENTE
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
VARDDNMPLCQDTGLAVVFVEMGQDVHIVGGDFNEAVQEGVRQAYRDGYLRKSLCDPLSR
HCCCCCCCCCCCCCCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHCHHHH
RNTGDNTPAVIFTELVPGDQLKLSAMPKGGGSENMSGSVMLTPAVGEAGIRAHVVDCVRR
CCCCCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHH
AGSNPCPPVVVGVGIGGSLEMSAVLAKKALLRPLGTANVRDERLAAMERELLTEINRLGI
CCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
GPQGYGGRVTALAVHVEMMPCHIASLPVTVNIQCHVARHREAVI
CCCCCCCEEEEEEEEEEEHHHEEECCCEEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]