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The map label for this gene is coaD

Identifier: 85373943

GI number: 85373943

Start: 1156812

End: 1157324

Strand: Direct

Name: coaD

Synonym: ELI_05580

Alternate gene names: 85373943

Gene position: 1156812-1157324 (Clockwise)

Preceding gene: 85373942

Following gene: 85373944

Centisome position: 37.9

GC content: 59.65

Gene sequence:

>513_bases
ATGAACGAGCGCATCGGGGTCTATCCCGGCACATTCGACCCGATCACGCGAGGCCACCGCGACATCATCCGGCGCGGGGC
CAAGCTGGTCGATACCCTCATAATCGGTGTCACCACCAACCCGTCGAAGAACCCGATGTTCACGCCGGAAGAGCGGATGG
AGATGGTGAAAAAGGAACTCGCCGACATGGGCCTCGACAACACCGAGGTTGTCGGGTTCGATGCGTTGTTGATGAAATTC
GCGAAGAAGCAGAATGCAAACGTGATCGTGCGCGGGCTGCGCGCCGTCGCCGATTTCGAATACGAATACCAGATGGCGGG
CATGAACCAGCAGATCGATGCCGATATCGAGACGGTCTTCCTCATGGCCGACGTCTCGCTGCAGCCGATCGCGTCCAAGC
TGGTCAAGGAAATCGCGCTCTATGGCGGCGATATCTCGCCCTTCGTCAGCCCGGCGGTCAAAGCTCAGGTCGAGGCAAGG
GTCGAGAAAATCGGCCGCCGCGGGGACTATTGA

Upstream 100 bases:

>100_bases
GCGCACTGGTGGACCACGCGGTCGGCCACCTCGGGCAATATGGAGAAGATGCTGCGGTGCTGCGGGCACTCGCGCGCTAC
ATCGTCGAGAGGGACCGATA

Downstream 100 bases:

>100_bases
GGTCCGCGCGCATTTCCCCAAGCTATTAATTGCGGAGACAGCGCGGCGCGGTTAATGCGCGGGCAGACACGCCCCAACAC
TTCAGGATATCCATGATCAA

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT [H]

Number of amino acids: Translated: 170; Mature: 170

Protein sequence:

>170_residues
MNERIGVYPGTFDPITRGHRDIIRRGAKLVDTLIIGVTTNPSKNPMFTPEERMEMVKKELADMGLDNTEVVGFDALLMKF
AKKQNANVIVRGLRAVADFEYEYQMAGMNQQIDADIETVFLMADVSLQPIASKLVKEIALYGGDISPFVSPAVKAQVEAR
VEKIGRRGDY

Sequences:

>Translated_170_residues
MNERIGVYPGTFDPITRGHRDIIRRGAKLVDTLIIGVTTNPSKNPMFTPEERMEMVKKELADMGLDNTEVVGFDALLMKF
AKKQNANVIVRGLRAVADFEYEYQMAGMNQQIDADIETVFLMADVSLQPIASKLVKEIALYGGDISPFVSPAVKAQVEAR
VEKIGRRGDY
>Mature_170_residues
MNERIGVYPGTFDPITRGHRDIIRRGAKLVDTLIIGVTTNPSKNPMFTPEERMEMVKKELADMGLDNTEVVGFDALLMKF
AKKQNANVIVRGLRAVADFEYEYQMAGMNQQIDADIETVFLMADVSLQPIASKLVKEIALYGGDISPFVSPAVKAQVEAR
VEKIGRRGDY

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate [H]

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family [H]

Homologues:

Organism=Escherichia coli, GI1790065, Length=159, Percent_Identity=45.9119496855346, Blast_Score=158, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.3 [H]

Molecular weight: Translated: 18939; Mature: 18939

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNERIGVYPGTFDPITRGHRDIIRRGAKLVDTLIIGVTTNPSKNPMFTPEERMEMVKKEL
CCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHHH
ADMGLDNTEVVGFDALLMKFAKKQNANVIVRGLRAVADFEYEYQMAGMNQQIDADIETVF
HHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHCCCCCCCCCCCHHEEE
LMADVSLQPIASKLVKEIALYGGDISPFVSPAVKAQVEARVEKIGRRGDY
EEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNERIGVYPGTFDPITRGHRDIIRRGAKLVDTLIIGVTTNPSKNPMFTPEERMEMVKKEL
CCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHHH
ADMGLDNTEVVGFDALLMKFAKKQNANVIVRGLRAVADFEYEYQMAGMNQQIDADIETVF
HHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHCCCCCCCCCCCHHEEE
LMADVSLQPIASKLVKEIALYGGDISPFVSPAVKAQVEARVEKIGRRGDY
EEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA