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The map label for this gene is trkD

Identifier: 85060380

GI number: 85060380

Start: 4121485

End: 4123353

Strand: Reverse

Name: trkD

Synonym: SG2402

Alternate gene names: 85060380

Gene position: 4123353-4121485 (Counterclockwise)

Preceding gene: 85060399

Following gene: 85060379

Centisome position: 98.85

GC content: 53.5

Gene sequence:

>1869_bases
ATGAATAAAGATCATAAGCAGTCGCTGCCGGCGGTCACGCTTGCCGCCATAGGTGTCGTGTATGGTGATATTGGTACCAG
TCCTCTCTATACCTTACGTGAATGTCTTGCCGGCCATTATGGTTTTGGCGTTGAACGCGTGGCGGTATTTGGTTTCTTAT
CCCTCATTTTCTGGCTTCTGATCCTGATCGTTTCCCTGAAATATCTTCTCTTCGTCATGCGCGCCGACAATGCCGGCGAA
GGCGGTATTTTGACGCTAATGTCGCTCGCCGGCAGAAATACCGGCGCCAAATTGACCCCGGTACTGGTGATAATCGGGCT
TATCGGCGGCAGCTTCTTTTACGGCGAGGTCGTTATCACGCCGGCCGTCTCTGTGATGTCGGCGATTGAAGGGCTGCAAA
TCGTGGCCCCCTCGCTACAGGAATTTATCGTTCCTCTCTCCGTGGTGGTGCTGACGTTGCTGTTTTTCATCCAAAAGAAA
GGGACCGGCAGCGTCGGCAAACTTTTCGCGCCGGTGATGTTATTATGGTTTCTCACGCTGGGTGTACTGGGCGTGCGCGG
TATCATCTATAATCCCGAAGTGCTCTATGCCCTTAATCCGAAATGGGCTATCGCCTTTTTTGCCGAATATCGAACCGTCT
CCTTCTTCGCTCTGGGCGCGGTAGTGTTGGCTATCACCGGCGTAGAGGCGTTGTATGCCGATATGGGCCATTTCGGTAAA
TTGCCTATTCGCATCGCTTGGTTTAGCGCGGTGCTACCGTCCTTGGTGCTTAATTATTTCGGTCAGGGCGCGCTGTTATT
GTCCAAGCCGGCGGCAATCAAAAACCCTTTCTTTTTACTCGCCCCCGATTGGGCGATGATTCCATTGCTTATTCTTGCCA
CGCTTGCAACGGTCATCGCTTCACAGGCGGTGATCTCCGGCGTATTTTCCCTGACTCGCCAGGCGGTGCGCCTGGGGTAT
ATGCCGCCGATGCGCATCATTCATACCTCCGAGATGGAGGTGGGCCAGATTTATATTCCTTTCATCAACTGGCTGCTGTA
TATCGCCGTGGTGCTGGTAATTGTCAGCTTTGAGCACTCCAGCAATCTGGCGGCGGCCTACGGTATCGCGGTGACTGGCA
CCATGGTGCTGACCAGCATCCTGTCTTGTACCGTGGCCAGAAAAAACTGGCACTTGAATCTGTTAATTGTGTCCGTGCTG
CTGCTGGCGCTGTTGTGCCTCGATGTGTCTATGTTTGCCGCCAACGCCCTGAAGATTTTCTCTGGCGGCTGGCTACCGTT
GCTGCTGGGTTTCCTGATGTTCATCGCCATGATCACCTGGAAAAGCGAACGGTTCCTCTTGTTGCGACGGATCCATGAAC
ATGGAAATTCCCTGGAAGCGCTGATTGCCTCTTTGGAAAAATCGCCGCCGGTGCGGGTCCCCGGTACGGCCGTGTTTATG
TCGCGCGCTATGAACGTGATCCCGTTTGCCCTGCTACATAACCTCAAGCATAACAAAGTGCTGCATGAGCGCGTTGTGCT
GCTGACGCTGCGTACAGAGGATGCCCCTTTTGTCCATAATGTACGGCGGGTCACTATCGAAGCGCTATCGCCCACTTTCT
GGCGCGTCGTGGCAAGCTATGGTTTCAAAGAGGCGCCGGATATGGAGGAGATTTTCCACAGCTGCGGGCTTGAGGGGCTA
TCCTGCCGGATGATGGAAACGTCCTTTTTCATGTCTCATGAATCGCTTATTCTCGGCAAGCGGCCCTGGTATCTGATGAT
ACGGGGCAAACTTTTCATGGTGTTAAGCCGTAACGCCCTGCGCGCGCCGGATCAATATCTCATACCGCCTAACCGGGTCA
TTGAGTTGGGAACGCAAATAGAGATCTGA

Upstream 100 bases:

>100_bases
ATTAGGGTTTCGGCATTTTTCAGGCATACTGTGCGCTTTTGGTTTTCGAGGAAGTGCATTCACGCATGCTCCTGGACGAC
AAAATAGCTCGGGAAAGGTT

Downstream 100 bases:

>100_bases
CGATTCAATCATTTTCAGCCAGCAACTGCTGGCAGGCGGCGAAAGCGCCCGGACCATCGCCGGCGAAAATGGCATCCACG
ATGGCCTGATGCCGGCCAAG

Product: potassium transport protein Kup

Products: K (I) [Cytoplasm] [C]

Alternate protein names: Kup system potassium uptake protein

Number of amino acids: Translated: 622; Mature: 622

Protein sequence:

>622_residues
MNKDHKQSLPAVTLAAIGVVYGDIGTSPLYTLRECLAGHYGFGVERVAVFGFLSLIFWLLILIVSLKYLLFVMRADNAGE
GGILTLMSLAGRNTGAKLTPVLVIIGLIGGSFFYGEVVITPAVSVMSAIEGLQIVAPSLQEFIVPLSVVVLTLLFFIQKK
GTGSVGKLFAPVMLLWFLTLGVLGVRGIIYNPEVLYALNPKWAIAFFAEYRTVSFFALGAVVLAITGVEALYADMGHFGK
LPIRIAWFSAVLPSLVLNYFGQGALLLSKPAAIKNPFFLLAPDWAMIPLLILATLATVIASQAVISGVFSLTRQAVRLGY
MPPMRIIHTSEMEVGQIYIPFINWLLYIAVVLVIVSFEHSSNLAAAYGIAVTGTMVLTSILSCTVARKNWHLNLLIVSVL
LLALLCLDVSMFAANALKIFSGGWLPLLLGFLMFIAMITWKSERFLLLRRIHEHGNSLEALIASLEKSPPVRVPGTAVFM
SRAMNVIPFALLHNLKHNKVLHERVVLLTLRTEDAPFVHNVRRVTIEALSPTFWRVVASYGFKEAPDMEEIFHSCGLEGL
SCRMMETSFFMSHESLILGKRPWYLMIRGKLFMVLSRNALRAPDQYLIPPNRVIELGTQIEI

Sequences:

>Translated_622_residues
MNKDHKQSLPAVTLAAIGVVYGDIGTSPLYTLRECLAGHYGFGVERVAVFGFLSLIFWLLILIVSLKYLLFVMRADNAGE
GGILTLMSLAGRNTGAKLTPVLVIIGLIGGSFFYGEVVITPAVSVMSAIEGLQIVAPSLQEFIVPLSVVVLTLLFFIQKK
GTGSVGKLFAPVMLLWFLTLGVLGVRGIIYNPEVLYALNPKWAIAFFAEYRTVSFFALGAVVLAITGVEALYADMGHFGK
LPIRIAWFSAVLPSLVLNYFGQGALLLSKPAAIKNPFFLLAPDWAMIPLLILATLATVIASQAVISGVFSLTRQAVRLGY
MPPMRIIHTSEMEVGQIYIPFINWLLYIAVVLVIVSFEHSSNLAAAYGIAVTGTMVLTSILSCTVARKNWHLNLLIVSVL
LLALLCLDVSMFAANALKIFSGGWLPLLLGFLMFIAMITWKSERFLLLRRIHEHGNSLEALIASLEKSPPVRVPGTAVFM
SRAMNVIPFALLHNLKHNKVLHERVVLLTLRTEDAPFVHNVRRVTIEALSPTFWRVVASYGFKEAPDMEEIFHSCGLEGL
SCRMMETSFFMSHESLILGKRPWYLMIRGKLFMVLSRNALRAPDQYLIPPNRVIELGTQIEI
>Mature_622_residues
MNKDHKQSLPAVTLAAIGVVYGDIGTSPLYTLRECLAGHYGFGVERVAVFGFLSLIFWLLILIVSLKYLLFVMRADNAGE
GGILTLMSLAGRNTGAKLTPVLVIIGLIGGSFFYGEVVITPAVSVMSAIEGLQIVAPSLQEFIVPLSVVVLTLLFFIQKK
GTGSVGKLFAPVMLLWFLTLGVLGVRGIIYNPEVLYALNPKWAIAFFAEYRTVSFFALGAVVLAITGVEALYADMGHFGK
LPIRIAWFSAVLPSLVLNYFGQGALLLSKPAAIKNPFFLLAPDWAMIPLLILATLATVIASQAVISGVFSLTRQAVRLGY
MPPMRIIHTSEMEVGQIYIPFINWLLYIAVVLVIVSFEHSSNLAAAYGIAVTGTMVLTSILSCTVARKNWHLNLLIVSVL
LLALLCLDVSMFAANALKIFSGGWLPLLLGFLMFIAMITWKSERFLLLRRIHEHGNSLEALIASLEKSPPVRVPGTAVFM
SRAMNVIPFALLHNLKHNKVLHERVVLLTLRTEDAPFVHNVRRVTIEALSPTFWRVVASYGFKEAPDMEEIFHSCGLEGL
SCRMMETSFFMSHESLILGKRPWYLMIRGKLFMVLSRNALRAPDQYLIPPNRVIELGTQIEI

Specific function: Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system)

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family

Homologues:

Organism=Escherichia coli, GI48994960, Length=622, Percent_Identity=81.5112540192926, Blast_Score=1053, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KUP_SODGM (Q2NQ98)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_456082.1
- STRING:   Q2NQ98
- GeneID:   3868401
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG2402
- NMPDR:   fig|343509.6.peg.5186
- eggNOG:   COG3158
- HOGENOM:   HBG351154
- OMA:   ETINIPR
- PhylomeDB:   Q2NQ98
- ProtClustDB:   PRK10745
- BioCyc:   SGLO343509:SG2402-MONOMER
- HAMAP:   MF_01522
- InterPro:   IPR003855
- InterPro:   IPR023051
- TIGRFAMs:   TIGR00794

Pfam domain/function: PF02705 K_trans

EC number: NA

Molecular weight: Translated: 68540; Mature: 68540

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1094b74c)-; HASH(0x113b27f8)-; HASH(0x10fec0f8)-; HASH(0x1076c098)-; HASH(0x104fac94)-; HASH(0x10fe92b8)-; HASH(0x1079f990)-; HASH(0xf09cd2c)-; HASH(0x113cd980)-; HASH(0x113b2774)-; HASH(0xcf2a2ec)-; HASH(0x113ca74c)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKDHKQSLPAVTLAAIGVVYGDIGTSPLYTLRECLAGHYGFGVERVAVFGFLSLIFWLL
CCCCCHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
ILIVSLKYLLFVMRADNAGEGGILTLMSLAGRNTGAKLTPVLVIIGLIGGSFFYGEVVIT
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEECHHHHH
PAVSVMSAIEGLQIVAPSLQEFIVPLSVVVLTLLFFIQKKGTGSVGKLFAPVMLLWFLTL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
GVLGVRGIIYNPEVLYALNPKWAIAFFAEYRTVSFFALGAVVLAITGVEALYADMGHFGK
HHHHHCCEEECCEEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LPIRIAWFSAVLPSLVLNYFGQGALLLSKPAAIKNPFFLLAPDWAMIPLLILATLATVIA
CCHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHCCCEEEECCCHHHHHHHHHHHHHHHHH
SQAVISGVFSLTRQAVRLGYMPPMRIIHTSEMEVGQIYIPFINWLLYIAVVLVIVSFEHS
HHHHHHHHHHHHHHHHHHCCCCCHHEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCC
SNLAAAYGIAVTGTMVLTSILSCTVARKNWHLNLLIVSVLLLALLCLDVSMFAANALKIF
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGGWLPLLLGFLMFIAMITWKSERFLLLRRIHEHGNSLEALIASLEKSPPVRVPGTAVFM
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHH
SRAMNVIPFALLHNLKHNKVLHERVVLLTLRTEDAPFVHNVRRVTIEALSPTFWRVVASY
HHHHHHHHHHHHHHCHHHHHHHHEEEEEEEECCCCCHHHHHHHHHHHHHCHHHHHHHHHC
GFKEAPDMEEIFHSCGLEGLSCRMMETSFFMSHESLILGKRPWYLMIRGKLFMVLSRNAL
CCCCCCCHHHHHHHCCCCCCEEEEEHHHHHHCCCCEEECCCCEEEEEECEEEEEEECCHH
RAPDQYLIPPNRVIELGTQIEI
CCCCCCCCCCHHHEECCCCCCH
>Mature Secondary Structure
MNKDHKQSLPAVTLAAIGVVYGDIGTSPLYTLRECLAGHYGFGVERVAVFGFLSLIFWLL
CCCCCHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
ILIVSLKYLLFVMRADNAGEGGILTLMSLAGRNTGAKLTPVLVIIGLIGGSFFYGEVVIT
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEECHHHHH
PAVSVMSAIEGLQIVAPSLQEFIVPLSVVVLTLLFFIQKKGTGSVGKLFAPVMLLWFLTL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
GVLGVRGIIYNPEVLYALNPKWAIAFFAEYRTVSFFALGAVVLAITGVEALYADMGHFGK
HHHHHCCEEECCEEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LPIRIAWFSAVLPSLVLNYFGQGALLLSKPAAIKNPFFLLAPDWAMIPLLILATLATVIA
CCHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHCCCEEEECCCHHHHHHHHHHHHHHHHH
SQAVISGVFSLTRQAVRLGYMPPMRIIHTSEMEVGQIYIPFINWLLYIAVVLVIVSFEHS
HHHHHHHHHHHHHHHHHHCCCCCHHEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCC
SNLAAAYGIAVTGTMVLTSILSCTVARKNWHLNLLIVSVLLLALLCLDVSMFAANALKIF
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGGWLPLLLGFLMFIAMITWKSERFLLLRRIHEHGNSLEALIASLEKSPPVRVPGTAVFM
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHH
SRAMNVIPFALLHNLKHNKVLHERVVLLTLRTEDAPFVHNVRRVTIEALSPTFWRVVASY
HHHHHHHHHHHHHHCHHHHHHHHEEEEEEEECCCCCHHHHHHHHHHHHHCHHHHHHHHHC
GFKEAPDMEEIFHSCGLEGLSCRMMETSFFMSHESLILGKRPWYLMIRGKLFMVLSRNAL
CCCCCCCHHHHHHHCCCCCCEEEEEHHHHHHCCCCEEECCCCEEEEEECEEEEEEECCHH
RAPDQYLIPPNRVIELGTQIEI
CCCCCCCCCCHHHEECCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA