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The map label for this gene is cat [H]

Identifier: 85060079

GI number: 85060079

Start: 3629358

End: 3630827

Strand: Reverse

Name: cat [H]

Synonym: SG2101

Alternate gene names: 85060079

Gene position: 3630827-3629358 (Counterclockwise)

Preceding gene: 85060082

Following gene: 85060075

Centisome position: 87.05

GC content: 55.99

Gene sequence:

>1470_bases
ATGAAAGATAAAACGCTGTTAACTACCGCCAGCGGTATCCCGGTGGCCGATAATCAGAACTCCCGATCCGCCGGAGCGCG
GGGGCCATTGATGCTGGACGATTTTCATCTGGTGGAAAAACTGGCCCATTTTAACCGCGAAGTGATTCCCGAGCGGCGCG
TGCATGCCAAAGGGTCCGGCGCCTATGGGACGTTTCGCGTGACTCAGGACATCCGCCGGCTGACTACCGCGTCGCCCTTT
GAGCACATCGGCAAAGAGACGCCGGTATTACTGCGTTTTTCAACCGTGGGTGGCGAGCGTGGCTCGGCGGACACCGAGCG
GGATCCACGCGGTTTTGCGCTGAAATTTTATACCGAACAGGGTAACTGGGATGTGGTGGGTAATAACACACCGGTCTTTT
TTATCCGCGATCCGCTGAAATTTCCTGATTTTATCCATACCCAAAAACGGGATCCGGCGACGAATCTGAAATCCCCCCAG
ATGATGTGGGACTTCTGGTCTTTATCGCCGGAGTCGATGCATCAAGTCACCATTTTGTTTTCCGATCGCGGTATTCCCGA
TGGTTACCGTTTTATGCACGGTTTTGGCAGCCATACCTATAGCCTGATCAATGCTGACGGCGAGCGAGTGTTTATTAAAT
GGCATTTTAAAACGCTTCAGGGCATCAAAAACCTGACGGTGGAAGAGGCCGGCCGTCTGGCGGGCAGCGATCCGGATTAT
GCACAGCGCGATCTGTTCAGCGCTATCGAGCGGGGCGATTGTCCGCGCTGGCGGGTTTGCATCCAGCTCATGACCGAGCA
GGAAGCCGCACAGCGTCAGGAAAATCCGTTCGATGTCACCAAAGTTTGGTCGCAGAAAACCCATCCGTTGCAGGAGGTGG
GTATCCTGGAACTTAATCGTAACCCGGACAACTATTTCGCGGAGGTCGAACAGGCGGCGTTCGCGCCTAGCAATGTGGTA
CCCGGCATCGGCCTGTCGCCGGATAAGATGCTGCAGGGACGGGTATTCGCCTATGCCGACGCCCAACGTTACCGCATCGG
TACCAATTACCAGCAGCTACCGGTTAACGCGCCGCACTGCCCCTATCACAATTATCAGCGTGACGGCGCCATGCGTTTTG
ACGCTAACGGCGGCGGAACGCCTAATTACGAGCCGAATAGGTATGCTACCTCGCAGCAGCAGGCACCAGGGTTTAGGGAG
CCACCGCTGAATTTCAGCGGCGCGGCGGATCGTTATGACCATCGCGTGGATGAAGATTATTACAGCCAGGCTGGTGATCT
TTATCGATTGATGGACTCACAGCAGAAAACGCTGCTGACGGCCAATCTGGTCAGGGCCCTGGCGCCGGTAACCCGGGACG
TCCAACTGCGACAAATTGCGCATTTCCTGCGGGCGGATGTTGATTACGGCCGCGCGGTGGCGCAAGGGCTGGGAATTGAA
GACGAGATACTGACCTCGGTCGGCGTTTAA

Upstream 100 bases:

>100_bases
TCAGCTATTGAGTTGATAGATGCAATGAATTAGCCACCTTAGCCGCTGCGCTATAAAGTGGGCTCAGAGTTCCCTTTCCT
TTACCGTGAGCCTGAATATT

Downstream 100 bases:

>100_bases
AGGATCTCGGCGCCGTGGGGCTGATGTCTTACAGGTTAGGCGTTGGCGCCGGCGCGCCCTTCAGGCTTAGGGCGATTGGC
CCGTGCACGCGCTTTCAGGG

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MKDKTLLTTASGIPVADNQNSRSAGARGPLMLDDFHLVEKLAHFNREVIPERRVHAKGSGAYGTFRVTQDIRRLTTASPF
EHIGKETPVLLRFSTVGGERGSADTERDPRGFALKFYTEQGNWDVVGNNTPVFFIRDPLKFPDFIHTQKRDPATNLKSPQ
MMWDFWSLSPESMHQVTILFSDRGIPDGYRFMHGFGSHTYSLINADGERVFIKWHFKTLQGIKNLTVEEAGRLAGSDPDY
AQRDLFSAIERGDCPRWRVCIQLMTEQEAAQRQENPFDVTKVWSQKTHPLQEVGILELNRNPDNYFAEVEQAAFAPSNVV
PGIGLSPDKMLQGRVFAYADAQRYRIGTNYQQLPVNAPHCPYHNYQRDGAMRFDANGGGTPNYEPNRYATSQQQAPGFRE
PPLNFSGAADRYDHRVDEDYYSQAGDLYRLMDSQQKTLLTANLVRALAPVTRDVQLRQIAHFLRADVDYGRAVAQGLGIE
DEILTSVGV

Sequences:

>Translated_489_residues
MKDKTLLTTASGIPVADNQNSRSAGARGPLMLDDFHLVEKLAHFNREVIPERRVHAKGSGAYGTFRVTQDIRRLTTASPF
EHIGKETPVLLRFSTVGGERGSADTERDPRGFALKFYTEQGNWDVVGNNTPVFFIRDPLKFPDFIHTQKRDPATNLKSPQ
MMWDFWSLSPESMHQVTILFSDRGIPDGYRFMHGFGSHTYSLINADGERVFIKWHFKTLQGIKNLTVEEAGRLAGSDPDY
AQRDLFSAIERGDCPRWRVCIQLMTEQEAAQRQENPFDVTKVWSQKTHPLQEVGILELNRNPDNYFAEVEQAAFAPSNVV
PGIGLSPDKMLQGRVFAYADAQRYRIGTNYQQLPVNAPHCPYHNYQRDGAMRFDANGGGTPNYEPNRYATSQQQAPGFRE
PPLNFSGAADRYDHRVDEDYYSQAGDLYRLMDSQQKTLLTANLVRALAPVTRDVQLRQIAHFLRADVDYGRAVAQGLGIE
DEILTSVGV
>Mature_489_residues
MKDKTLLTTASGIPVADNQNSRSAGARGPLMLDDFHLVEKLAHFNREVIPERRVHAKGSGAYGTFRVTQDIRRLTTASPF
EHIGKETPVLLRFSTVGGERGSADTERDPRGFALKFYTEQGNWDVVGNNTPVFFIRDPLKFPDFIHTQKRDPATNLKSPQ
MMWDFWSLSPESMHQVTILFSDRGIPDGYRFMHGFGSHTYSLINADGERVFIKWHFKTLQGIKNLTVEEAGRLAGSDPDY
AQRDLFSAIERGDCPRWRVCIQLMTEQEAAQRQENPFDVTKVWSQKTHPLQEVGILELNRNPDNYFAEVEQAAFAPSNVV
PGIGLSPDKMLQGRVFAYADAQRYRIGTNYQQLPVNAPHCPYHNYQRDGAMRFDANGGGTPNYEPNRYATSQQQAPGFRE
PPLNFSGAADRYDHRVDEDYYSQAGDLYRLMDSQQKTLLTANLVRALAPVTRDVQLRQIAHFLRADVDYGRAVAQGLGIE
DEILTSVGV

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=472, Percent_Identity=54.6610169491525, Blast_Score=529, Evalue=1e-150,
Organism=Escherichia coli, GI48994891, Length=495, Percent_Identity=43.8383838383838, Blast_Score=392, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI71998444, Length=472, Percent_Identity=52.5423728813559, Blast_Score=517, Evalue=1e-147,
Organism=Caenorhabditis elegans, GI25151141, Length=476, Percent_Identity=50, Blast_Score=492, Evalue=1e-139,
Organism=Caenorhabditis elegans, GI25147792, Length=476, Percent_Identity=49.5798319327731, Blast_Score=490, Evalue=1e-139,
Organism=Saccharomyces cerevisiae, GI6320462, Length=487, Percent_Identity=48.2546201232033, Blast_Score=434, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6321525, Length=536, Percent_Identity=38.2462686567164, Blast_Score=361, Evalue=1e-100,
Organism=Drosophila melanogaster, GI17981717, Length=480, Percent_Identity=51.875, Blast_Score=507, Evalue=1e-144,
Organism=Drosophila melanogaster, GI19920968, Length=478, Percent_Identity=47.907949790795, Blast_Score=465, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 55221; Mature: 55221

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDKTLLTTASGIPVADNQNSRSAGARGPLMLDDFHLVEKLAHFNREVIPERRVHAKGSG
CCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHCHHHCCCHHCCCCCCC
AYGTFRVTQDIRRLTTASPFEHIGKETPVLLRFSTVGGERGSADTERDPRGFALKFYTEQ
CCEEEHHHHHHHHHHCCCCHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEEEEC
GNWDVVGNNTPVFFIRDPLKFPDFIHTQKRDPATNLKSPQMMWDFWSLSPESMHQVTILF
CCEEEECCCCCEEEEECCCCCCHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCCEEEEEEE
SDRGIPDGYRFMHGFGSHTYSLINADGERVFIKWHFKTLQGIKNLTVEEAGRLAGSDPDY
ECCCCCCHHHHHHHCCCCEEEEEECCCCEEEEEEECHHHHHHHHCCHHHHHCCCCCCCCH
AQRDLFSAIERGDCPRWRVCIQLMTEQEAAQRQENPFDVTKVWSQKTHPLQEVGILELNR
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHCCEEEECC
NPDNYFAEVEQAAFAPSNVVPGIGLSPDKMLQGRVFAYADAQRYRIGTNYQQLPVNAPHC
CCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCEEEEEECCHHEEECCCCCCCCCCCCCC
PYHNYQRDGAMRFDANGGGTPNYEPNRYATSQQQAPGFREPPLNFSGAADRYDHRVDEDY
CCCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCHHHHHHCCHHH
YSQAGDLYRLMDSQQKTLLTANLVRALAPVTRDVQLRQIAHFLRADVDYGRAVAQGLGIE
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHCCCCC
DEILTSVGV
HHHHHHCCC
>Mature Secondary Structure
MKDKTLLTTASGIPVADNQNSRSAGARGPLMLDDFHLVEKLAHFNREVIPERRVHAKGSG
CCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHCHHHCCCHHCCCCCCC
AYGTFRVTQDIRRLTTASPFEHIGKETPVLLRFSTVGGERGSADTERDPRGFALKFYTEQ
CCEEEHHHHHHHHHHCCCCHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEEEEC
GNWDVVGNNTPVFFIRDPLKFPDFIHTQKRDPATNLKSPQMMWDFWSLSPESMHQVTILF
CCEEEECCCCCEEEEECCCCCCHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCCEEEEEEE
SDRGIPDGYRFMHGFGSHTYSLINADGERVFIKWHFKTLQGIKNLTVEEAGRLAGSDPDY
ECCCCCCHHHHHHHCCCCEEEEEECCCCEEEEEEECHHHHHHHHCCHHHHHCCCCCCCCH
AQRDLFSAIERGDCPRWRVCIQLMTEQEAAQRQENPFDVTKVWSQKTHPLQEVGILELNR
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHCCEEEECC
NPDNYFAEVEQAAFAPSNVVPGIGLSPDKMLQGRVFAYADAQRYRIGTNYQQLPVNAPHC
CCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCEEEEEECCHHEEECCCCCCCCCCCCCC
PYHNYQRDGAMRFDANGGGTPNYEPNRYATSQQQAPGFREPPLNFSGAADRYDHRVDEDY
CCCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCHHHHHHCCHHH
YSQAGDLYRLMDSQQKTLLTANLVRALAPVTRDVQLRQIAHFLRADVDYGRAVAQGLGIE
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHCCCCC
DEILTSVGV
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA