BacMap

Definition	Sodalis glossinidius str. 'morsitans', complete genome.
Accession	NC_007712
Length	4,171,146

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The map label for this gene is znuC

Identifier: 85059241

GI number: 85059241

Start: 2124185

End: 2124952

Strand: Reverse

Name: znuC

Synonym: SG1263

Alternate gene names: 85059241

Gene position: 2124952-2124185 (Counterclockwise)

Preceding gene: 85059244

Following gene: 85059234

Centisome position: 50.94

GC content: 56.51

Gene sequence:

>768_bases
ATGACCGACTTGGTAGCCCTTGAACACATTGCCGTCGCCTTCGGGCGAAAAGCGGTACTGCACGATATCTCATTTACCCT
GCGCCACGGACACATTCTCACCCTGCTCAGCCCGAATGGCGCCGGTAAATCGACGCTGGTGTGGGTAGTGCTCAGCCTTA
TTGCGCCCGATGCCCGCACAATAAGGCGCCAGCCTAAACTGCGCGTGGGTTATGTGCCGCAGAAAATTCATATTGATCCC
ACGCTGCCGCTGACGGTCGAACGCTTCATGCGTCTGCATCCGGGGGTGAAGAAAGGCGATATTGGACCGGCGCTCGCGCG
GGTGCAGGCGCAGCATTTGCATCAGGCTCCAATGCAGAAGCTATCCGGCGGTGAAATGCAATGGGTGCTGCTGGCGCGCG
CCCTGCTCAATTCACCACAACTCTTGGTGCTGGATGAGCCTACTCAAGGCGTGGACGTCAACGGTCAGGTGGCGCTGTAT
GATTTAATCGACAACCTTCGCCATACGCTCGGTTACGGCGTATTAATGGTGTCCCACGATTTACATCTGGTGATGGCGAA
AATCGATGAAATGCTGTGCCTTAATCGCCATATCTGCTGTTCCGGTACTCCGGAAGTGGTCTCGGCCCATCCGGATTTTA
TTGCCATGTTCGGCTATCGTGAATCATCGCAGCTCGCCATTTACCGCCATCATCACAATCACCGCCACGATTTACAGGGC
GAGGTCATGCCGGCCGCGCAGCCGCACGGAGAGTGCCGCCATGATTGA

Upstream 100 bases:

>100_bases
CACGACGGTGGAAAGGGAGGCGGGCATGGCAATATTCTCATCGGTAACCAAGCAGATTGTTATGTTATAGTAACGCGGCA
ATTTAACAATCGTAATCATC

Downstream 100 bases:

>100_bases
ATTATTGCTGCCCGGCTGGGTTGCTGGCCTGCTGCTTTCGCTGGCGGCGGGTCCACTCGGCGCCTTCGTGGTCTGGCGCA
AGATGTCGTATTTTGGCGAT

Product: high-affinity zinc transporter ATPase

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MTDLVALEHIAVAFGRKAVLHDISFTLRHGHILTLLSPNGAGKSTLVWVVLSLIAPDARTIRRQPKLRVGYVPQKIHIDP
TLPLTVERFMRLHPGVKKGDIGPALARVQAQHLHQAPMQKLSGGEMQWVLLARALLNSPQLLVLDEPTQGVDVNGQVALY
DLIDNLRHTLGYGVLMVSHDLHLVMAKIDEMLCLNRHICCSGTPEVVSAHPDFIAMFGYRESSQLAIYRHHHNHRHDLQG
EVMPAAQPHGECRHD

Sequences:

>Translated_255_residues
MTDLVALEHIAVAFGRKAVLHDISFTLRHGHILTLLSPNGAGKSTLVWVVLSLIAPDARTIRRQPKLRVGYVPQKIHIDP
TLPLTVERFMRLHPGVKKGDIGPALARVQAQHLHQAPMQKLSGGEMQWVLLARALLNSPQLLVLDEPTQGVDVNGQVALY
DLIDNLRHTLGYGVLMVSHDLHLVMAKIDEMLCLNRHICCSGTPEVVSAHPDFIAMFGYRESSQLAIYRHHHNHRHDLQG
EVMPAAQPHGECRHD
>Mature_254_residues
TDLVALEHIAVAFGRKAVLHDISFTLRHGHILTLLSPNGAGKSTLVWVVLSLIAPDARTIRRQPKLRVGYVPQKIHIDPT
LPLTVERFMRLHPGVKKGDIGPALARVQAQHLHQAPMQKLSGGEMQWVLLARALLNSPQLLVLDEPTQGVDVNGQVALYD
LIDNLRHTLGYGVLMVSHDLHLVMAKIDEMLCLNRHICCSGTPEVVSAHPDFIAMFGYRESSQLAIYRHHHNHRHDLQGE
VMPAAQPHGECRHD

Specific function: Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system

COG id: COG1121

COG function: function code P; ABC-type Mn/Zn transport systems, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain

Homologues:

Organism=Homo sapiens, GI27436953, Length=226, Percent_Identity=29.646017699115, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI27477115, Length=216, Percent_Identity=27.3148148148148, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI153792144, Length=195, Percent_Identity=28.7179487179487, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI6005701, Length=215, Percent_Identity=27.906976744186, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI31657092, Length=212, Percent_Identity=29.2452830188679, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI27881506, Length=199, Percent_Identity=25.6281407035176, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI10947137, Length=199, Percent_Identity=25.6281407035176, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI148612853, Length=196, Percent_Identity=30.6122448979592, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1788165, Length=243, Percent_Identity=73.2510288065844, Blast_Score=360, Evalue=1e-101,
Organism=Escherichia coli, GI1790739, Length=223, Percent_Identity=31.8385650224215, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1789593, Length=224, Percent_Identity=29.0178571428571, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI87081709, Length=232, Percent_Identity=28.448275862069, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1788506, Length=217, Percent_Identity=30.4147465437788, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788761, Length=226, Percent_Identity=29.2035398230088, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787370, Length=235, Percent_Identity=27.6595744680851, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI87081834, Length=186, Percent_Identity=33.3333333333333, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1789864, Length=247, Percent_Identity=25.5060728744939, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789891, Length=191, Percent_Identity=30.8900523560209, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1786319, Length=221, Percent_Identity=28.0542986425339, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1790544, Length=238, Percent_Identity=24.7899159663866, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1787182, Length=192, Percent_Identity=31.25, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1787041, Length=208, Percent_Identity=26.9230769230769, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI48994883, Length=225, Percent_Identity=27.1111111111111, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786803, Length=236, Percent_Identity=26.6949152542373, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788450, Length=248, Percent_Identity=27.0161290322581, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1790190, Length=203, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87081791, Length=230, Percent_Identity=27.3913043478261, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI48995001, Length=226, Percent_Identity=26.5486725663717, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789991, Length=204, Percent_Identity=25.9803921568627, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789873, Length=220, Percent_Identity=29.0909090909091, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790467, Length=230, Percent_Identity=28.2608695652174, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789751, Length=190, Percent_Identity=27.8947368421053, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI48994943, Length=217, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789962, Length=227, Percent_Identity=25.5506607929515, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1786703, Length=217, Percent_Identity=29.0322580645161, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI87081782, Length=231, Percent_Identity=25.974025974026, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788897, Length=206, Percent_Identity=27.6699029126214, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1786345, Length=222, Percent_Identity=26.5765765765766, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1786975, Length=206, Percent_Identity=28.6407766990291, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1786872, Length=223, Percent_Identity=26.457399103139, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788225, Length=236, Percent_Identity=24.1525423728814, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788472, Length=87, Percent_Identity=33.3333333333333, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=188, Percent_Identity=28.1914893617021, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17555318, Length=201, Percent_Identity=30.3482587064677, Blast_Score=78, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6321121, Length=180, Percent_Identity=32.7777777777778, Blast_Score=80, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24666092, Length=193, Percent_Identity=27.979274611399, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24642252, Length=182, Percent_Identity=30.2197802197802, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI18859989, Length=182, Percent_Identity=30.2197802197802, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24641342, Length=189, Percent_Identity=28.042328042328, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI116007184, Length=186, Percent_Identity=25.8064516129032, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI221500365, Length=186, Percent_Identity=25.8064516129032, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24650853, Length=169, Percent_Identity=31.9526627218935, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24650855, Length=169, Percent_Identity=31.9526627218935, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ZNUC_SODGM (Q2NTI7)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_454943.1
- ProteinModelPortal:   Q2NTI7
- SMR:   Q2NTI7
- STRING:   Q2NTI7
- GeneID:   3867870
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG1263
- NMPDR:   fig|343509.6.peg.2608
- eggNOG:   COG1121
- HOGENOM:   HBG758042
- OMA:   AGIAHML
- PhylomeDB:   Q2NTI7
- ProtClustDB:   PRK09544
- BioCyc:   SGLO343509:SG1263-MONOMER
- HAMAP:   MF_01725
- InterPro:   IPR003439
- InterPro:   IPR017882
- InterPro:   IPR003593
- SMART:   SM00382

Pfam domain/function: PF00005 ABC_tran

EC number: NA

Molecular weight: Translated: 28414; Mature: 28282

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: PS00211 ABC_TRANSPORTER_1; PS50893 ABC_TRANSPORTER_2; PS51298 ZNUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLVALEHIAVAFGRKAVLHDISFTLRHGHILTLLSPNGAGKSTLVWVVLSLIAPDART
CCCHHHHHHHHHHHCCHHHHHHHHEEEECCEEEEEECCCCCCCHHHHHHHHHHHCCCHHH
IRRQPKLRVGYVPQKIHIDPTLPLTVERFMRLHPGVKKGDIGPALARVQAQHLHQAPMQK
HHCCCCEEECCCCCEEEECCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LSGGEMQWVLLARALLNSPQLLVLDEPTQGVDVNGQVALYDLIDNLRHTLGYGVLMVSHD
HCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHEEEEEECC
LHLVMAKIDEMLCLNRHICCSGTPEVVSAHPDFIAMFGYRESSQLAIYRHHHNHRHDLQG
HHHHHHHHHHHHHHCCCEECCCCCHHEECCCCEEEEECCCCCCCEEEEECCCCCCCCCCC
EVMPAAQPHGECRHD
CCCCCCCCCCCCCCC
>Mature Secondary Structure 
TDLVALEHIAVAFGRKAVLHDISFTLRHGHILTLLSPNGAGKSTLVWVVLSLIAPDART
CCHHHHHHHHHHHCCHHHHHHHHEEEECCEEEEEECCCCCCCHHHHHHHHHHHCCCHHH
IRRQPKLRVGYVPQKIHIDPTLPLTVERFMRLHPGVKKGDIGPALARVQAQHLHQAPMQK
HHCCCCEEECCCCCEEEECCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LSGGEMQWVLLARALLNSPQLLVLDEPTQGVDVNGQVALYDLIDNLRHTLGYGVLMVSHD
HCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHEEEEEECC
LHLVMAKIDEMLCLNRHICCSGTPEVVSAHPDFIAMFGYRESSQLAIYRHHHNHRHDLQG
HHHHHHHHHHHHHHCCCEECCCCCHHEECCCCEEEEECCCCCCCEEEEECCCCCCCCCCC
EVMPAAQPHGECRHD
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA