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The map label for this gene is yeiG [H]

Identifier: 85058934

GI number: 85058934

Start: 1575499

End: 1576335

Strand: Reverse

Name: yeiG [H]

Synonym: SG0956

Alternate gene names: 85058934

Gene position: 1576335-1575499 (Counterclockwise)

Preceding gene: 85058939

Following gene: 85058931

Centisome position: 37.79

GC content: 61.29

Gene sequence:

>837_bases
ATGACCGTCAACGCTGAGCGCATTGCGGCCCACCGCCTGTATGGCAGCTGGCAGTACCGCTACCGACATCGATCCCAGGC
GACCGGCGTGCCGATGACCTATAGCGTCTATGTGCCGCCGGAAGCAGCGGATAAACGGCCGCCTCAGGTGATCTTCTGGT
TGTCGGGCCTGACCTGCACCGATGAAAACTTTAGCACCAAGTCGGGCGCGCAGCGCCTGGCCGCCGAGCTTAATTTGCTG
TTGGTGATGCCCGATACCAGCCCGCGCGGCGAGGCGGTGGCCTACGATCTGGGCCAAGGGGCGGGCTTTTATCTCAACGC
CACGGTCGCGCTCTGGTCATCCCATTATCGGATGTTCGATTACCTCAGCGACGAACTGCCGGCGCTTATCCGCCAACAGT
TCAGCACGGGGGATCGCCAGTCTATCATGGGCCATTCGATGGGCGGCCACGGCGCGCTGTTAATGGCGCTGCGTCATCCG
AGGCGTTATTGCTCGGTGTCGGCTTTTGCGCCGATCGTCAATCCCAGCGAGGTGCCCTGGGGCCGTAAAGCTTTCGGCGA
GTATATGGGTCAGGACGAGAAAGCTTGGCGGCAATGGGACAGCTGCCGACTACTTGCCGACGGCGGCGCGCAGCCGCTGC
CGGTGTTAATAGATCAAGGCGACGCTGATCCGTTCATGCCGGAACAGCTGCAACCGGAAACATGGGCCGCGCTGGCGCGC
CAGCATCAATGGCCGCTGACGTTGCGTATCCAGCCGGGCTATGACCACAGCTATTTCTTTATCGCCAGCTTTATCGATGA
TCACCTGCGGTTCCACGCCGGTTATCTGCACACCTGA

Upstream 100 bases:

>100_bases
TATGGGACTTGAGGCGATAAATGAAGCGTTCAGCCTGATGCATGAAGGCAAATCGATCCGTTCCGTTATCCATTTCGGCC
AGTGATAAAAGGAGACAGCA

Downstream 100 bases:

>100_bases
TCCCTCGCTGTAACACCCTCTGTCCGGAGGAATGACGTTCCCCCGGATGCTAAAATTCGACGACTACCGTCCCCGGCCGG
TGCAGAGAGAGGGGTTCCCC

Product: putative esterase

Products: NA

Alternate protein names: FGH [H]

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MTVNAERIAAHRLYGSWQYRYRHRSQATGVPMTYSVYVPPEAADKRPPQVIFWLSGLTCTDENFSTKSGAQRLAAELNLL
LVMPDTSPRGEAVAYDLGQGAGFYLNATVALWSSHYRMFDYLSDELPALIRQQFSTGDRQSIMGHSMGGHGALLMALRHP
RRYCSVSAFAPIVNPSEVPWGRKAFGEYMGQDEKAWRQWDSCRLLADGGAQPLPVLIDQGDADPFMPEQLQPETWAALAR
QHQWPLTLRIQPGYDHSYFFIASFIDDHLRFHAGYLHT

Sequences:

>Translated_278_residues
MTVNAERIAAHRLYGSWQYRYRHRSQATGVPMTYSVYVPPEAADKRPPQVIFWLSGLTCTDENFSTKSGAQRLAAELNLL
LVMPDTSPRGEAVAYDLGQGAGFYLNATVALWSSHYRMFDYLSDELPALIRQQFSTGDRQSIMGHSMGGHGALLMALRHP
RRYCSVSAFAPIVNPSEVPWGRKAFGEYMGQDEKAWRQWDSCRLLADGGAQPLPVLIDQGDADPFMPEQLQPETWAALAR
QHQWPLTLRIQPGYDHSYFFIASFIDDHLRFHAGYLHT
>Mature_277_residues
TVNAERIAAHRLYGSWQYRYRHRSQATGVPMTYSVYVPPEAADKRPPQVIFWLSGLTCTDENFSTKSGAQRLAAELNLLL
VMPDTSPRGEAVAYDLGQGAGFYLNATVALWSSHYRMFDYLSDELPALIRQQFSTGDRQSIMGHSMGGHGALLMALRHPR
RYCSVSAFAPIVNPSEVPWGRKAFGEYMGQDEKAWRQWDSCRLLADGGAQPLPVLIDQGDADPFMPEQLQPETWAALARQ
HQWPLTLRIQPGYDHSYFFIASFIDDHLRFHAGYLHT

Specific function: Serine hydrolase involved in the detoxification of formaldehyde. Hydrolyzes S-formylglutathione to glutathione and formate [H]

COG id: COG0627

COG function: function code R; Predicted esterase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the esterase D family [H]

Homologues:

Organism=Homo sapiens, GI33413400, Length=279, Percent_Identity=45.8781362007168, Blast_Score=266, Evalue=1e-71,
Organism=Escherichia coli, GI1788477, Length=276, Percent_Identity=63.768115942029, Blast_Score=361, Evalue=1e-101,
Organism=Escherichia coli, GI1786551, Length=276, Percent_Identity=49.2753623188406, Blast_Score=286, Evalue=1e-78,
Organism=Caenorhabditis elegans, GI17510185, Length=281, Percent_Identity=43.7722419928826, Blast_Score=238, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6322393, Length=282, Percent_Identity=41.1347517730496, Blast_Score=209, Evalue=5e-55,
Organism=Drosophila melanogaster, GI45551932, Length=286, Percent_Identity=45.8041958041958, Blast_Score=253, Evalue=1e-67,
Organism=Drosophila melanogaster, GI24648347, Length=279, Percent_Identity=45.8781362007168, Blast_Score=252, Evalue=2e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000801
- InterPro:   IPR014186 [H]

Pfam domain/function: PF00756 Esterase [H]

EC number: =3.1.2.12 [H]

Molecular weight: Translated: 31440; Mature: 31309

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVNAERIAAHRLYGSWQYRYRHRSQATGVPMTYSVYVPPEAADKRPPQVIFWLSGLTCT
CCCCHHHHHHHHHHCCHHEEEECCCCCCCCCEEEEEEECCCCCCCCCCEEEEEECCCEEC
DENFSTKSGAQRLAAELNLLLVMPDTSPRGEAVAYDLGQGAGFYLNATVALWSSHYRMFD
CCCCCCHHHHHHHHHCCEEEEEECCCCCCCCEEEEECCCCCCEEEEEHEEEHHHHHHHHH
YLSDELPALIRQQFSTGDRQSIMGHSMGGHGALLMALRHPRRYCSVSAFAPIVNPSEVPW
HHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHCCHHHHCHHHHCCCCCCCCCCC
GRKAFGEYMGQDEKAWRQWDSCRLLADGGAQPLPVLIDQGDADPFMPEQLQPETWAALAR
CHHHHHHHHCCCHHHHHHHHCEEEEECCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHH
QHQWPLTLRIQPGYDHSYFFIASFIDDHLRFHAGYLHT
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TVNAERIAAHRLYGSWQYRYRHRSQATGVPMTYSVYVPPEAADKRPPQVIFWLSGLTCT
CCCHHHHHHHHHHCCHHEEEECCCCCCCCCEEEEEEECCCCCCCCCCEEEEEECCCEEC
DENFSTKSGAQRLAAELNLLLVMPDTSPRGEAVAYDLGQGAGFYLNATVALWSSHYRMFD
CCCCCCHHHHHHHHHCCEEEEEECCCCCCCCEEEEECCCCCCEEEEEHEEEHHHHHHHHH
YLSDELPALIRQQFSTGDRQSIMGHSMGGHGALLMALRHPRRYCSVSAFAPIVNPSEVPW
HHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHCCHHHHCHHHHCCCCCCCCCCC
GRKAFGEYMGQDEKAWRQWDSCRLLADGGAQPLPVLIDQGDADPFMPEQLQPETWAALAR
CHHHHHHHHCCCHHHHHHHHCEEEEECCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHH
QHQWPLTLRIQPGYDHSYFFIASFIDDHLRFHAGYLHT
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA