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The map label for this gene is yajL [H]

Identifier: 85058638

GI number: 85058638

Start: 1122672

End: 1123436

Strand: Reverse

Name: yajL [H]

Synonym: SG0660

Alternate gene names: 85058638

Gene position: 1123436-1122672 (Counterclockwise)

Preceding gene: 85058639

Following gene: 85058636

Centisome position: 26.93

GC content: 62.48

Gene sequence:

>765_bases
ATGGACAAATCGATTCTTCTCTGTCTGGCCGATGGTAGCGAGGAAACCGAAGCCGTCACGACGTTCGATTTGTTGGTACG
CGCCGGAATGCAGGTACGCGCGGCCAGCGTCAACGGCGATGGCGGATTGACCATCGTCGGTTCGCGCGGCGTACGGCTGC
TGGCCGATGCGCCGCTGGCGCCTTTAGCGGAGCAGCCCTTTGACGCCATTGTCCTCCCCAGCGATATGCAGGGCGCCGAG
TGTTTCCAGCGCAGTCCGCTGCTCCTGGAGTGCGTACGCCGAATGCACCTCGACGGTAAACTGGTGGCGGCGATATGCGC
CGCCCCGGCCTTGGTATTGCAACACCATCAGCTGTTTAGCCAAGCCTATATGACCGGTTTTCCGGCGCTGAAGGACCGTA
TTCCCGCCGATCGCTGGGTGGATCAGCGGGTCGTCCATGATGCGCGTTACCGGCTCCTCACCAGCCAGGGGCCGGGGACG
GCCATGGATTTCGCCCTGAACATTATCGCGTTGCTCTGCGGCCTTCCGGCCGCGGCCGAGGTGGCGGCCGAGGTGGCGGC
ACAGGTTAGTACTACCCCAGGGCATTGCAAATTTTCAAGATTAGCTATGTATCAAACCAGAGGTTCGGCGAGCGCGGGCA
GAATATGCAGGAGGGGGCTGCAAAAGGCCTGCAGCAGGTGCAGGACAACATGGGCAGCGGGGCAAGACACAACCCGCGGC
AGGCGCGGGCCGCATTCTCGCTGGAAGCGCCCGCCGGCAATTTAA

Upstream 100 bases:

>100_bases
TACATTACCGGCCATGTCCTGCGGCGCGCACGTGCGCACGGGCTGAATATGCCGAAGAATCAGCGGCTATTTGATTGGGT
GAAACGCAAGGAGGAAAGCT

Downstream 100 bases:

>100_bases
GGGCGGTAAACCTTCACGTTTTGGAAGCCCTGCTCGCGCAAATAGAGCGCCTGCAAGCGACTCATCACCCCACGGTCGCA
GTACAGTAAGTATAATTTAC

Product: 4-methyl-5(beta-hydroxyethyl)-thiazole synthesis

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MDKSILLCLADGSEETEAVTTFDLLVRAGMQVRAASVNGDGGLTIVGSRGVRLLADAPLAPLAEQPFDAIVLPSDMQGAE
CFQRSPLLLECVRRMHLDGKLVAAICAAPALVLQHHQLFSQAYMTGFPALKDRIPADRWVDQRVVHDARYRLLTSQGPGT
AMDFALNIIALLCGLPAAAEVAAEVAAQVSTTPGHCKFSRLAMYQTRGSASAGRICRRGLQKACSRCRTTWAAGQDTTRG
RRGPHSRWKRPPAI

Sequences:

>Translated_254_residues
MDKSILLCLADGSEETEAVTTFDLLVRAGMQVRAASVNGDGGLTIVGSRGVRLLADAPLAPLAEQPFDAIVLPSDMQGAE
CFQRSPLLLECVRRMHLDGKLVAAICAAPALVLQHHQLFSQAYMTGFPALKDRIPADRWVDQRVVHDARYRLLTSQGPGT
AMDFALNIIALLCGLPAAAEVAAEVAAQVSTTPGHCKFSRLAMYQTRGSASAGRICRRGLQKACSRCRTTWAAGQDTTRG
RRGPHSRWKRPPAI
>Mature_254_residues
MDKSILLCLADGSEETEAVTTFDLLVRAGMQVRAASVNGDGGLTIVGSRGVRLLADAPLAPLAEQPFDAIVLPSDMQGAE
CFQRSPLLLECVRRMHLDGKLVAAICAAPALVLQHHQLFSQAYMTGFPALKDRIPADRWVDQRVVHDARYRLLTSQGPGT
AMDFALNIIALLCGLPAAAEVAAEVAAQVSTTPGHCKFSRLAMYQTRGSASAGRICRRGLQKACSRCRTTWAAGQDTTRG
RRGPHSRWKRPPAI

Specific function: Involved in biogenesis of ribosomal proteins, probably as a ribosomal protein-folding chaperone. Interacts with ribosomal subunits, ribosomes and polysomes. Confers resistance to oxidative stress [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C56 family [H]

Homologues:

Organism=Homo sapiens, GI183227678, Length=185, Percent_Identity=35.6756756756757, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI31543380, Length=185, Percent_Identity=35.6756756756757, Blast_Score=89, Evalue=3e-18,
Organism=Escherichia coli, GI87081736, Length=185, Percent_Identity=61.0810810810811, Blast_Score=224, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI17531319, Length=175, Percent_Identity=32.5714285714286, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17558714, Length=175, Percent_Identity=32.5714285714286, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI28571932, Length=184, Percent_Identity=40.7608695652174, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24653499, Length=187, Percent_Identity=33.6898395721925, Blast_Score=77, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006287
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 27360; Mature: 27360

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKSILLCLADGSEETEAVTTFDLLVRAGMQVRAASVNGDGGLTIVGSRGVRLLADAPLA
CCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEECCCEEEEECCCCC
PLAEQPFDAIVLPSDMQGAECFQRSPLLLECVRRMHLDGKLVAAICAAPALVLQHHQLFS
CHHCCCCCEEEECCCCCHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
QAYMTGFPALKDRIPADRWVDQRVVHDARYRLLTSQGPGTAMDFALNIIALLCGLPAAAE
HHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHCCCHHHH
VAAEVAAQVSTTPGHCKFSRLAMYQTRGSASAGRICRRGLQKACSRCRTTWAAGQDTTRG
HHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
RRGPHSRWKRPPAI
CCCCHHHCCCCCCC
>Mature Secondary Structure
MDKSILLCLADGSEETEAVTTFDLLVRAGMQVRAASVNGDGGLTIVGSRGVRLLADAPLA
CCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEECCCEEEEECCCCC
PLAEQPFDAIVLPSDMQGAECFQRSPLLLECVRRMHLDGKLVAAICAAPALVLQHHQLFS
CHHCCCCCEEEECCCCCHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
QAYMTGFPALKDRIPADRWVDQRVVHDARYRLLTSQGPGTAMDFALNIIALLCGLPAAAE
HHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHCCCHHHH
VAAEVAAQVSTTPGHCKFSRLAMYQTRGSASAGRICRRGLQKACSRCRTTWAAGQDTTRG
HHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
RRGPHSRWKRPPAI
CCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 9592144 [H]