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The map label for this gene is mdtJ

Identifier: 85058608

GI number: 85058608

Start: 1074592

End: 1074972

Strand: Reverse

Name: mdtJ

Synonym: SG0630

Alternate gene names: 85058608

Gene position: 1074972-1074592 (Counterclockwise)

Preceding gene: 85058609

Following gene: 85058607

Centisome position: 25.77

GC content: 51.44

Gene sequence:

>381_bases
ATGATTTACTGGATCTTTTTAGCACTCGCCATAACGGCCGAAGTTATCGGCACGCTGTCGATGAAATATGCCACCGTCAA
CGGCCAAATAACCGGTCATATTGTGATGTACATTATGATCACCGCCTCCTACATCCTGTTATCGCTGGCGATTAAACGGG
TAGCGTTGGGGGTCGCCTATGCGCTGTGGGAAGGCATCGGTATTCTGTTTATTACTCTGTTCAGCGTGATGTGGTTCGAT
GAGCCCTTTTCGTTGACCAAGCTGGCGGGGCTGGCCATTTTAGTCATCGGCATTGTGATGCTGAAATCCGGCACCCGTAA
AGCGCAGGGCGATAGCGGTCTGAAAGCGCGGCAGAAGGAGCGCCATCATGCAACAGTTTGA

Upstream 100 bases:

>100_bases
AGCTTAATCCCCGCCGGCAGCAATCCGTGACTGGCCCTCTGGCCGCACATCCCCCGGCATAAATGCCCCGACATGCGTGT
TATCCGTCGGGAGAATTACC

Downstream 100 bases:

>100_bases
TCTCTATCACTCCGGTTTCCTAGCGTCGGCGGTGGTATTGGAAATTTTGGCCAACATTTTGCTCAAAATGTCGGACGGTT
TTCGTAAATTGTGGCTGGGC

Product: multidrug efflux system protein MdtJ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 126; Mature: 126

Protein sequence:

>126_residues
MIYWIFLALAITAEVIGTLSMKYATVNGQITGHIVMYIMITASYILLSLAIKRVALGVAYALWEGIGILFITLFSVMWFD
EPFSLTKLAGLAILVIGIVMLKSGTRKAQGDSGLKARQKERHHATV

Sequences:

>Translated_126_residues
MIYWIFLALAITAEVIGTLSMKYATVNGQITGHIVMYIMITASYILLSLAIKRVALGVAYALWEGIGILFITLFSVMWFD
EPFSLTKLAGLAILVIGIVMLKSGTRKAQGDSGLKARQKERHHATV
>Mature_126_residues
MIYWIFLALAITAEVIGTLSMKYATVNGQITGHIVMYIMITASYILLSLAIKRVALGVAYALWEGIGILFITLFSVMWFD
EPFSLTKLAGLAILVIGIVMLKSGTRKAQGDSGLKARQKERHHATV

Specific function: Catalyzes the excretion of spermidine

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. MdtJ subfamily

Homologues:

Organism=Escherichia coli, GI1787884, Length=125, Percent_Identity=60, Blast_Score=140, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MDTJ_SODGM (Q2NVC0)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_454310.1
- STRING:   Q2NVC0
- GeneID:   3868449
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG0630
- NMPDR:   fig|343509.6.peg.1382
- eggNOG:   COG2076
- HOGENOM:   HBG740972
- OMA:   AFWEGLG
- PhylomeDB:   Q2NVC0
- ProtClustDB:   PRK10452
- BioCyc:   SGLO343509:SG0630-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01598
- InterPro:   IPR000390

Pfam domain/function: PF00893 Multi_Drug_Res

EC number: NA

Molecular weight: Translated: 13847; Mature: 13847

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xd938a14)-; HASH(0xdb0a79c)-; HASH(0xdee6a04)-; HASH(0xd745790)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYWIFLALAITAEVIGTLSMKYATVNGQITGHIVMYIMITASYILLSLAIKRVALGVAY
CHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALWEGIGILFITLFSVMWFDEPFSLTKLAGLAILVIGIVMLKSGTRKAQGDSGLKARQKE
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
RHHATV
HCCCCH
>Mature Secondary Structure
MIYWIFLALAITAEVIGTLSMKYATVNGQITGHIVMYIMITASYILLSLAIKRVALGVAY
CHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALWEGIGILFITLFSVMWFDEPFSLTKLAGLAILVIGIVMLKSGTRKAQGDSGLKARQKE
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
RHHATV
HCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA